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                <text>&lt;strong&gt;Potential of Red Winemaking Byproducts as Health-Promoting Food Ingredients&lt;/strong&gt;</text>
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                <text>&lt;p&gt;The reduction of the environmental impact represents an important challenge&lt;br /&gt;for the winemaking industry. Red grape by-products are composed of several&lt;br /&gt;health-promoting components such as polyphenols and dietary fiber, which may&lt;br /&gt;be employed as sustainable food ingredients. Although the bioactive properties&lt;br /&gt;of red grape pomace, one of the most abundant byproducts of the winemaking&lt;br /&gt;industry worldwide, have been extensively documented by in vitro studies,&lt;br /&gt;there is a lack of information on the bioaccessibility, bioavailability and food&lt;br /&gt;applications that will subsequently affect the contribution of grape byproduct&lt;br /&gt;bioactive compounds to these properties. Therefore, the present chapter aimed&lt;br /&gt;to present some of the latest grape byproducts in vitro bioactive properties,&lt;br /&gt;as well as novel and updated knowledge related to its bioaccessibility,&lt;br /&gt;bioavailability and food applications.&lt;/p&gt;</text>
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                <text>Sustainable Innovation in Food Product Design / Maria Margarida Cortez Vieira, Lorenzo Pastrana y Jos&amp;eacute; Aguilera, eds. --&amp;nbsp;Cham : Springer , 2021. --&amp;nbsp;pp. 205-248</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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        <name>Bioaccesibilidad</name>
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        <name>Nutrición</name>
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        <name>Orujo de Uva</name>
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                <text>&lt;span&gt;The stereoselective synthesis of several components of the aggregation pheromones of numerous longhorn beetle species is described. These attractants consist of 3-hydroxy-2-alkanones and 2,3-alkyldiols&amp;shy; with chain lengths varying from six to ten carbons. The 3&lt;/span&gt;&lt;span class="i"&gt;R&lt;/span&gt;&lt;span&gt;- and 3&lt;/span&gt;&lt;span class="i"&gt;S&lt;/span&gt;&lt;span&gt;-series are generated by organocatalytic &amp;alpha;-hydroxylation of alkyl ketones with nitrosobenzene in the presence of&amp;nbsp;&lt;/span&gt;&lt;span class="sc"&gt;l&lt;/span&gt;&lt;span&gt;- or&amp;nbsp;&lt;/span&gt;&lt;span class="sc"&gt;d&lt;/span&gt;&lt;span&gt;-proline, respectively, to obtain the hydroxyketones in high enantiomeric excess. Further reduction and chromatographic separation lead to the enantiomerically pure diols that complete the library.&lt;/span&gt;</text>
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                <text>&lt;strong&gt;do Carmo, Hugo&lt;/strong&gt;</text>
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                <text>Synthesis (Germany),&amp;nbsp;v. 53, n&amp;deg;23, 2021. -- pp. 4501-4506</text>
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                <text>Synthesis (Germany),&amp;nbsp;v. 53, 2021. -- pp. 4501-4506</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;p&gt;Whey is an abundantand sustainable source of bioactive peptides obtained from cheese making process. Whey proteins such as &amp;alpha;-lactalbumin can be biologically active when the bioactive peptides encrypted in the amino acid sequence of the native protein are released by enzymatic hydrolysis. In&lt;br /&gt;the present work, the identification, sequence analysis, and antioxidant activity of bioaccessible peptides from &amp;alpha;-lactalbumin alcalase-hydrolysate was assessed.&lt;br /&gt;Antioxidant activity (ABTS, ORAC, andHORAC) of &amp;alpha;-lactalbumin showed a significant increase (p &amp;lt; 0.05) after the enzymatic treatment with alcalase and this capacity increased even more after the simulation of the gastrointestinal digestion&lt;br /&gt;process. Peptides contained in the gastrointestinal digest of &amp;alpha;-lactalbumin hydrolysate were separated by preparative RP-HPLC (55 fractions), and three peptides were identified by LC-MS/MS analysis from selected fractions: IWCKDDQNPH&lt;br /&gt;(MW: 1254.54 Da) f(59-68), KFLDDDLTDDIM (MW: 1439.64 Da) f(79-90), DKFLDDDLTDDIM (MW: 1554.67 Da) f(78-90). Among the chemically synthesized peptides, IWCKDDQNPH showed the highest antioxidant capacity determined byORAC,ABTS, andHORAC assays (IC50 0.015&amp;plusmn; 0.002, 0.45 &amp;plusmn; 0.02, and 1.30 &amp;plusmn; 0.05 mg/ml, respectively) and this activitymay be related to the amino acid sequence. This is the first report where these bioaccessible peptides from &amp;alpha;-&lt;br /&gt;lactalbumin hydrolysate were identified. The &amp;alpha;-lactalbumin hydrolysate could be employed as a functional antioxidant ingredient.&lt;/p&gt;</text>
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                <text>Journal of Food Science,&amp;nbsp;v. 86, n&amp;deg; 10, 2021. -- pp. 4479-4490.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;Phage-borne peptides and antibody fragments isolated from phage display libraries have proven to be versatile and&lt;br /&gt;valuable reagents for immunoassay development. Due to the lack of convenient and mild-condition methods for the labeling of the phage particles, isolated peptide/protein affinity ligands are commonly removed from the viral particles and conjugated to protein tracers or nanoparticles for analytical use. This abolishes the advantage of isolating ready-to-use affinity binders and creates the risk of affecting the polypeptide activity. To circumvent this problem, we optimized the phage display system to produce phage particles that express the affinity binder on pIII and a polyglycine short peptide fused to pVIII that allows the covalent attachment of tracer molecules employing sortase A. Using a llama heavy chain only variable domain (VHH) against the herbicide 2,4-D on pIII as the&lt;br /&gt;model, we showed that the phage can be extensively decorated with a rhodamine-LPETGG peptide conjugate or the protein&lt;br /&gt;nanoluciferase (Nluc) equipped with a C-terminal LPETGG peptide. The maximum labeling amounts of rhodamine-LPETGG and Nluc-LPETGG were 1238 &amp;plusmn; 63 and 102 &amp;plusmn; 16 per phage, respectively. The Nluc-labeled dual display phage was employed to develop a phage bioluminescent immunoassay (P-BLEIA) for the detection of 2,4-D. The limit of detection and 50% inhibition&lt;br /&gt;concentration of P-BLEIA were 0.491 and 2.15 ng mL&amp;minus;1, respectively, which represent 16-fold and 8-fold improvement compared to the phage enzyme-linked immunosorbent assay. In addition, the P-BLEIA showed good accuracy for the detection of 2,4-D in spiked samples.&lt;/p&gt;</text>
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                <text>Analytical Chemistry,&amp;nbsp;v. 93, n&amp;deg; 34, 2021 .-- pp. 11800-11808.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Characterization of melanoidins and color development in Dulce de Leche, a confectionary dairy product with high sucrose content:&amp;nbsp;evaluation of pH effect, an essential manufacturing process parameter&lt;/strong&gt;</text>
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                <text>&lt;p&gt;The effect on color of the initial pH employed in dulce de leche (DL) production was evaluated through physicochemical and spectroscopical characterization of the melanoidins formed in the process. Melanoidins originated at pH values of 6.5, 7.0,&lt;br /&gt;and 7.5, and they were released by the enzymatic hydrolysis of the protein backbone and purified by gel filtration. They showed a significant degree of polydispersity, in general, with molecular weights (MWs) below 1,800 Da. DL produced at a higher pH&lt;br /&gt;released melanoidins with higher average MW after the enzymatic hydrolysis. They also presented darker colors (dE&amp;lowast;ab, C&amp;lowast;), more closely resembling those typical of the commercial product. Analysis of the fractions isolated by gel filtration using HPLC-DAD and multinuclear NMR showed an heterogeneous and complex composition. Even though structurally related, the 1H NMR spectra of melanoidins showed a higher degree of aromaticity at higher pH values. In conclusion, the pH employed in DL production affects the amount and structure of the colored products originated by MR reactions, and thus the color of the final product.&lt;/p&gt;</text>
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                <text>Frontiers in Nutrition&amp;nbsp;v. 8, 2021. --e753476</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Monitoring the transition period in dairy cows through 1H NMR-based untargeted metabolomics&lt;/strong&gt;</text>
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                <text>&lt;p&gt;The metabolic alterations associated with the increase in milk production make the transition period critical to the health of dairy cows, usually leading to a higher incidence of disease in periparturient animals. In this manuscript, we describe the use of NMR-based untargeted metabolomics to follow how these changes impact the serum metabolome in a group of 28 transition dairy cows with no initial clinical diseases. Principal component analysis (PCA) of serum 1H NMR data from&lt;br /&gt;four weeks before calving to 8 weeks after parturition allowed us to clearly identify four stages during the transition period. Pairwise comparisons using orthogonal partial least square discriminant analysis (OPLS-DA) and univariate data analysis led to the identification of 18 metabolites that varied significantly through these stages. Species such as acetate, betaine, and creatine are observed early after calving, while other markers of metabolic stress, including acetone, �-hydroxybutyrate (BHB), and choline, accumulate significantly at the height of milk production. Furthermore, marked&lt;br /&gt;variations in the levels of lactate, allantoin, alanine, and other amino acids reveal the activation of different gluconeogenic pathways following parturition. Concomitant with a return to homeostasis, a gradual normalization of the serum metabolome occurs 8 weeks after calving. Correlations of metabolite levels with dietary and metabolic adaptations based on animal parity could also be identified. Overall, these results show that NMR-based chemometric methods are ideally suited to monitor manifestations of metabolic diseases throughout the transition period and to assess the impact of nutritional management schemes on the metabolism of dairy cows.&lt;/p&gt;</text>
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                <text>Diary,&amp;nbsp;v.2, 2021. --pp. 356.366</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                <text>&lt;strong&gt;Analysis of the policy process for the implementation of nutritional warning labels in Uruguay&lt;/strong&gt;</text>
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                <text>2021</text>
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                <text>Objective: To analyse the process for the development and implementation of&amp;nbsp;mandatory nutritional warning labels inUruguay, in order to inform future nutrition&amp;nbsp;policy making and strategic engagement by public health actors.&lt;br /&gt;Design: The study design drew on policy analysis methodology&amp;nbsp; and case study&amp;nbsp;research methodology. Two main sources of information were selected and analysed&amp;nbsp;for the current study: eighteen official documents from the Uruguayan government&lt;br /&gt;and 259 news reports, published between June 2017 and February 2021.&lt;br /&gt;Setting: Uruguay, Latin America.&lt;br /&gt;Results: The Uruguayan Ministry of Public Health led a cross-sectoral working&amp;nbsp;group composed of diverse governmental stakeholders, international organisations&amp;nbsp;and the academia to develop the front-of-package nutrition labelling policy.&lt;br /&gt;A robust evidence-based approach, based on rigorous scientific knowledge generated&amp;nbsp;in the country, was followed. However, changes in the systemic governing&amp;nbsp;coalition as a consequence of a change in government led to a delay in the entry into force and changes in the regulation. The food industry was the main opponent&amp;nbsp;to the warning label regulation and relied on widely reported corporate political&amp;nbsp;activities to influence the policy process: information and messaging, legal action,&amp;nbsp;policy substitution, opposition, fragmentation and destabilisation.&lt;br /&gt;Conclusions: Key insights to inform future policy action in Uruguay and other jurisdictions&amp;nbsp;were derived. Results stressed the importance of an evidence-based&amp;nbsp;approach for policy design and the early engagement with actors from all the political&lt;br /&gt;system.</text>
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                <text>Public Health Nutrition,&amp;nbsp;v. 24, n&amp;deg; 17, 2021. -- pp. 5927&amp;ndash;5940</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;T- and pH-Dependent Kinetics of the Reactions of &amp;middot;OH(aq) with Glutaric and Adipic Acid for Atmospheric Aqueous-Phase Chemistry&lt;/strong&gt;</text>
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                <text>CINETICA DE COMPETENCIA</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>&lt;p&gt;Glutaric acid and adipic acid are dicarboxylic acids (DCAs) that are commonly found in atmospheric aerosols and cloud droplets. Within this study, the temperature- and pH-dependent rate constants of aqueous-phase OH radical reactions&lt;br /&gt;of these two DCAs were determined through the competition kinetics method. The following Arrhenius expressions were derived for the temperature dependency of the OH radical reaction with glutaric acid: k(T, H2A) = (3.9 &amp;plusmn; 0.1) &amp;times; 1010 &amp;times; exp[(&amp;minus;1270 &amp;plusmn; 200 K)/T], k(T, HA&amp;minus;) = (2.3 &amp;plusmn; 0.1) &amp;times; 1011 &amp;times; exp[(&amp;minus;1660 &amp;plusmn; 190 K)/T], k(T, A2&amp;minus;) = (1.4 &amp;plusmn; 0.1) &amp;times; 1011 &amp;times; exp[(&amp;minus;1400 &amp;plusmn; 170 K)/T]. Similarly, for adipic acid: k(T, H2A)&lt;br /&gt;= (7.5 &amp;plusmn; 0.2) &amp;times; 1010 &amp;times; exp[(&amp;minus;1210 &amp;plusmn; 170 K)/T], k(T, HA&amp;minus;) = (9.5 &amp;plusmn; 0.3) &amp;times; 1010 &amp;times; exp[(&amp;minus;1200 &amp;plusmn; 200 K)/T], k(T, A2&amp;minus;) = (8.7 &amp;plusmn; 0.2) &amp;times; 1010 &amp;times; exp[(&amp;minus;1100 &amp;plusmn; 170 K)/T] (in units of L mol&amp;minus;1 s&amp;minus;1). Density functional theory (DFT) calculations were performed to calculate the energy barrier of the H atom abstraction. The calculation results show that the energy barriers at the C&amp;beta;-atoms of the two DCAs are much lower than those at the C&amp;alpha;-atoms, indicating that the H atom abstractions predominantly occur at the C&amp;beta;-atoms. The increased &amp;middot;OH rate constant in the case of the deprotonated form can be explained by the reduction of energy barrier, which is predominately caused by the variation of the inductive effect of the carboxyl group. As an important sink in the atmosphere, the degradation of glutaric acid and adipic acid by &amp;middot;OH under atmospheric conditions can be accurately described by the Arrhenius expressions obtained.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Wen, Liang&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Schaefer, Thomas&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;He, Lin&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Zhang, Yimu&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Sun, Xiaomin&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Herrmann, Hartmut&lt;/strong&gt;</text>
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                <text>ACS Earth and Space Chemistry,&amp;nbsp;v. 5, n&amp;deg; 8, 2021. -- pp. 1854-1864.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p align="JUSTIFY"&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Arial, sans-serif;"&gt;&lt;span style="font-size: small;"&gt;&lt;span&gt;10.1021/acsearthspacechem.1c00163&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;</text>
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        <name>Ácido adípico</name>
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        <name>Cinética de competencia</name>
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                <text>&lt;strong&gt;Is COVID-19 a threat or an opportunity for healthy eating?:&amp;nbsp;an exploration of the factors that moderate the impact of the pandemic on eating habits in Uruguay&lt;/strong&gt;</text>
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                <text>&lt;p&gt;In May 2020, Uruguay was one of the few Latin American countries that had managed to control the outbreak of&lt;br /&gt;COVID-19 without mandatory curfews or quarantines. However, several social distancing measures created a major disruption in different aspects of the daily life of Uruguayan citizens. In this context, the objectives of the present work were i) to identify changes in eating habits perceived by Uruguayan citizens as a consequence of the COVID-19 pandemic, and ii) to explore factors associated with different perceived changes on eating habits. A cross-sectional online study was conducted with 891 participants, recruited using an advertisement on Facebook&lt;br /&gt;and Instagram. Fifty-one percent of the participants indicated that their eating habits had changed since the detection of the first cases of COVID-19 in Uruguay. Large heterogeneity in the categorization of the changes existed: 45% of the participants regarded the changes as positive, 32% as negative and 23% as neither positive nor negative. A multinomial logistic regression analysis was used to study the influence of explanatory variables in the likelihood of belonging to groups who reported different changes in eating habits (no changes, positive,&lt;br /&gt;negative, or neither positive nor negative changes). Household income and reliance on instrumental and emotional support increased the likelihood of reporting positive changes in eating habits, whereas negative changes were associated with a reduction in household income due to COVID-19 and the coping strategies selfdistraction and self-blaming. Insights for policy making to reinforce positive effects and minimize threats to&lt;br /&gt;healthy eating are discussed.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?e13bee77c03cddbef59b397e314055a6622de73c70417f3162757bfad754bfa8ad01125204736ed535ca050230cfa514a6e43d3d2464b7fea2cb77f4995d0c4b" target="_blank"&gt;&lt;strong&gt;Vidal, Leticia&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Brunet, Ger&amp;oacute;nimo&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Curutchet, Mar&amp;iacute;a Rosa&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Girona, Alejandra&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pardi&amp;ntilde;as, Valeria&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Guerra, Daniella&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Platero, Estefan&amp;iacute;a&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Machado, Luc&amp;iacute;a&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Gonz&amp;aacute;lez, Fernanda&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Gugliucci, Vanessa&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?e41ee09b825f22635cb8a1e9b42b334d75d1c2be0ccaad4f086d148a0ebac442b4a82cfb05ef977a8fe31965e28ee4bb8889f1ccb549f56f20a9403e2c02a0cf" target="_blank"&gt;&lt;strong&gt;Ares, Gast&amp;oacute;n&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Appetite,&amp;nbsp;v. 167, 2021. -- e105651</text>
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                <text>&lt;p&gt;In the search of antimicrobial agents a novel bisthiazole ligand containing a methylamine linker (ethyl 2-((2-methylthiazole-4-yl)methylamino)thiazole-4-carboxylate (BTa) and its copper(II) complex [CuCl2BTa]&amp;sdot;2H2O were synthetized. Both compounds were characterized by analytical and spectroscopic methods. Single crystal Xray diffraction of copper complex evidence a pentacoordinated copper(II) center of intermediate geometry&lt;br /&gt;forming 5 and 7 membered chelate rings with BTa acting as a tridentate ligand leaving the amine N&amp;ndash;H group in the thiazole linker available for participation in intermolecular interactions. Structure packing was analyzed by means of Hirshfeld surfaces, 2D fingerprint plots and lattice interaction energies were assessed. In order to deepen the understanding of the coordination to the flexible ligand DFT studies were carried out at the B3LYP/LANL2DZ level of theory. Calculated FTIR frequencies were used to perform a Vibrational Energy Distribution Analysis (VEDA) where potential energy distribution of vibrational was determined. Minimum inhibitory concentrations for BTa and CuBTa on E. coli ATCC 25922, S. aureus ATCC 25923, P. aeruginosa ATCC 9027 and C. albicans ATCC 10231 were determined.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Zero-trans fats designed by enzyme-catalyzed interesterification of rice bran oil and fully hydrogenated rice bran oil&amp;nbsp;&lt;/strong&gt;</text>
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                <text>&lt;p&gt;Zero-trans edible fats attractive to be used for shortenings or margarines were designed solely from rice bran oil (RBO). For this purpose, RBO was fully hydrogenated, blended with the original oil at different percentages, and finally, blends were interesterified by an enzyme-catalyzed process. The&lt;br /&gt;interesterification process reduced the concentration of trisaturated and triunsaturated triglycerides and increased the concentration of medium saturation degree molecules, thus increasing their compatibility and causing the moderation of the melting point, as compared with blends. Conversely to blends, products showed a high tendency to crystallize under the b&amp;rsquo; polymorph, which is the preferred one for products destined for many edible applications. Results demonstrated that the proper combination of different technologies (total hydrogenation, blending and interesterification) is a versatile and useful technology for designing zero-trans fats from RBO, attractive for the confection of shortenings or margarines for different&lt;br /&gt;applications depending on the proportion of each component in the starting blend. This strategy offers an attractive alternative for the diversification of RBO utilization, a valuable vegetable oil still underexploited, providing attractive fats useful for structuring different type of foods.&lt;/p&gt;</text>
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                <text>(2021) OCL - Oilseeds and fats, Crops and Lipids,&amp;nbsp;v. 28, 2021. -- e46</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;span id="docs-internal-guid-edad6986-7fff-fa72-407a-12749912c0a9"&gt;&lt;span&gt;10.1051/ocl/2021036&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Heteroleptic oxidovanadium(V) complexes with activity against infective and non-infective stages of Trypanosoma cruzi&amp;nbsp;&lt;/strong&gt;</text>
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                <text>VANADIO</text>
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                <text>&lt;p&gt;Five heteroleptic compounds, [VVO(IN-2H)(L-H)], where L are 8-hydroxyquinoline derivatives and IN is a Schiff base ligand, were synthesized and characterized in both the solid and solution state. The compounds were evaluated on epimastigotes and trypomastigotes of Trypanosoma cruzi as well as on VERO cells, as a mammalian cell model. Compounds showed activity against trypomastigotes with IC50 values of 0.29&amp;ndash;3.02 �M. IN ligand and the new [VVO2(IN-H)] complex showed negligible activity. The most active compound [VVO(IN-2H)(L2-H)], with L2 = 5-chloro-7-iodo- 8-hydroxyquinoline, showed good selectivity towards the parasite and was selected to carry out further biological studies. Stability studies suggested a partial decomposition in solution. [VVO(IN-2H)(L2-H)] affects the infection potential of cell-derived trypomastigotes. Low total vanadium uptake by parasites and preferential accumulation in the soluble proteins fraction were determined. A trypanocide effect was observed when incubating epimastigotes with 10 � IC50 values of [VVO(IN-2H)(L2-H)] and the generation of ROS after treatments was suggested. Fluorescence competition measurements with DNA:ethidium bromide adduct showed a moderate DNA interaction of the complexes. In vivo toxicity study on C. elegans model showed no toxicity up to a 100 �M concentration of [VVO(IN-2H)(L2-H)]. This compound could be considered a prospective anti-T. cruzi agent that deserves further research.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?30f70e9dfd00c43ffab403face2bbb4fd0f8853410743d6fa48798782e4078d5bf0735c77ca026b5828f7194ff3401bbfd4bd422c0ea61fda7a3ceb0a5af09f8" target="_blank"&gt;&lt;strong&gt;Scalese, Gonzalo&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?6bb5dcce3e2559101357796ca4a2b2d4c9ba6b3a978a0bd4c5dab0107081b73e1ff46dcf49a7de2b571ff7980c4a01789f09f1d7eac1b879a8553641f940b9a5" target="_blank"&gt;&lt;strong&gt;Gambino, Dinorah&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Molecules, v. 26, n&amp;deg; 17, 2021. -- e5375</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Raman spectroscopy signatures for monomeric, dimeric and trimeric zinc dimethoxide with tetrahydrofuran adduct and early:&lt;/strong&gt;</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>&lt;p&gt;It is widely accepted that the use of alkyl zinc and alkyl zinc alkoxide precursors are usually preferred instead of the popularly used zinc acetate precursor to obtaining better control on the synthesis of different zinc-oxo clusters and nanostructures. However, there are very few reports about zinc dialkoxides precursors and not many ones studying these precursors in a typical hydrolysiscondensation route. In the present report, we focus on the study of zinc dimethoxide structural features and their Raman spectroscopy signatures in the absence and presence of tetrahydrofuran (THF) adduct. Our theoretical calculations using Density Functional Theory (DFT) reveal that monomeric, dimeric and trimeric zinc dimethoxide exhibit distinctive Raman signatures, particularly at the low frequency region. In addition, some particular vibrational modes of zinc dimethoxide also evidenced some characteristic shifting and splitting in the presence of explicit THF coordination molecules. Our experimental approach using&lt;br /&gt;surface-enhanced Raman spectroscopy (SERS) reveals a quite complex combination of Raman signatures associated to zinc&lt;br /&gt;dimethoxide clusters corroborating tetrahydrofuran coordination and further early hydrolysis-condensation scenario. We aim to&lt;br /&gt;shed some light on the chemical structure of this particular zinc dimethoxide precursor and some of its early hydrolysis condensation products employing a powerful, popular and versatile technique such as Raman spectroscopy as it can be a&lt;br /&gt;promising candidate to access and simultaneously monitor the formation of novel zinc-oxo clusters and nanostructures.&lt;/p&gt;</text>
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                <text>Journal of Sol-Gel Science and Technology, 2021.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;span id="docs-internal-guid-ae7c466c-7fff-af01-4111-ef838e40387e"&gt;&lt;span&gt;10.1007/s10971-021-05607-w&lt;/span&gt;&lt;/span&gt;</text>
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                  <text>Bibliografía Nacional Química</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                <text>&lt;strong&gt;Synthesis and characterization of a bovine collagen:&amp;nbsp;GAG scaffold with Uruguayan raw material for tissue engineering&lt;/strong&gt;</text>
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                <text>CELULAS MADRE</text>
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                <text>&lt;p&gt;Tissue engineering (TE) and regenerative medicine offer strategies to improve damaged tissues by using scaffolds and cells. The use of collagen-based biomaterials in the field of TE has been intensively growing over the past decades. Mesenchymal stromal cells (MSCs) and dental pulp stem cells (DPSCs) are promising cell candidates for development of clinical composites. In this study, we proposed the development&lt;br /&gt;of a bovine collagen type I: chondroitin-6-sulphate (CG) scaffold, obtained from Uruguayan raw material (certified as free bovine spongiform encephalopathy), with CG crosslinking enhancement using different gamma radiation doses. Structural, biomechanical and chemical characteristics of the&lt;br /&gt;scaffolds were assessed by Scanning Electron Microscopy,&lt;br /&gt;axial tensile tests, FT-IR and Raman Spectroscopy,&lt;br /&gt;respectively. Once we selected the most appropriate scaffold for future use as a TE product, we studied the behavior of MSCs and DPSCs cultured on the scaffold by cytotoxicity, proliferation and differentiation assays. Among the diverse porous scaffolds&lt;br /&gt;obtained, the one with the most adequate properties was the one exposed to 15 kGy of gamma radiation.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Echarte, L.&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?78facf0d0598ff2d59e7d90838f411b31afeb5a103be562009253ef1cc970564aee3fa56b166096dc30501ce91cad2f944cbf24dc7018b21d346c5edead388b2" target="_blank"&gt;&lt;strong&gt;Romero, M.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Grazioli, G.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;P&amp;eacute;rez Campos, H.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Francia, A.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Vicentino, W.&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?1b0a087e3c87093cbc890b5bf91c399442e82cecc6f88c2cf9bc2d893c994b60b23ca38b16378acce4a04af7b21e8aad8d2952e078de5c23f190942588f4006c" target="_blank"&gt;&lt;strong&gt;Mombr&amp;uacute;, &amp;Aacute;lvaro W.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?2f2e59581473324400ee29ded741b9090cc25a893e73d02669ebfbc674c9e8b9b51bb30e2bca064dc7ebbd5c39aa3c844e86e507301e912aa1b0a5ae17423fa2" target="_blank"&gt;&lt;strong&gt;Faccio, Ricardo&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;&amp;Aacute;lvarez, I.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Touri&amp;ntilde;o, C.&lt;/strong&gt;</text>
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                <text>Cell and Tissue Banking, 2021.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Crystal structure and magnetic properties of 3,5-pyridinedicarboxylatebridged Re(II)M(II) heterodinuclear complexes (M = Cu, Ni and Co)&lt;/strong&gt;</text>
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                <text>&lt;p&gt;The use of the mononuclear rhenium(II) precursor NBu4[Re(NO)Br4(H2pydc)]&amp;sdot;i-PrOH (1) (H2pydc = 3,5-pyridinedicarboxylic acid) as a metalloligand towards Cu(II), Ni(II) and Co(II) afforded three new heterobimetallic&lt;br /&gt;complexes [Re(NO)Br4(&amp;mu;-Hpydc)Cu(4,4&amp;prime; dmbipy)2]&amp;sdot;(CH3)2CO&amp;sdot;0.25MeCN (2), [Re(NO)Br4(&amp;mu;-Hpydc)Ni&lt;br /&gt;(dmphen)2]&amp;sdot;MeCN (3) and [Re(NO)Br4(&amp;mu; Hpydc)Co(dmphen)2]&amp;sdot;2H2O (4), respectively [4,4&amp;prime; -dmbipy = 4,4&amp;prime; -dimethyl-2,2&amp;prime; -bipyridine, dmphen = 2,9-dimethyl-1,10-phenanthroline and Bu4N+ = tetra-n-butylammonium].&lt;br /&gt;The crystal structures of 1 and 2 are reported herein together with the cryomagnetic investigation of 1&amp;ndash;4 in the&lt;br /&gt;temperature range of 2.0&amp;ndash;300 K. 1 is a mononuclear compound whose structure is made of [Re(NO) Br4(H2pydc)]- complex anions, tetra-n-butylammonium cations and isopropanol molecules of crystallization. Each rhenium(II) ion in 1 is six-coordinate with four bromide ligands in the equatorial positions and a nitrosyl group and one pyridyl-nitrogen atom from an H2pydc ligand filling the axial sites. 2 is a neutral heterobimetallic compound where the [Re(NO)Br4(Hpydc)]2- complex anion acts as a monodentate ligand towards the [Cu(4,4&amp;prime; -dmbipy)2]2+ complex cation through one carboxylate&amp;ndash;oxygen atom. The rhenium(II) ion is six-coordinate in a somewhat distorted octahedral surrounding similar to that in 1. The copper(II) ion in 2 is five-coordinate with four nitrogen atoms from two bidentate 4,4&amp;prime; -dmbipy ligands and one carboxylate&amp;ndash;oxygen atom, describing a surrounding intermediate between square pyramidal and trigonal bipyramidal. Compound 1 behaves as a quasimagnetically&lt;br /&gt;isolated spin doublet with weak antiferromagnetic interactions through space Br⋯Br contacts, ligand field, spin&amp;ndash;orbit coupling, tetragonal distortion, and covalence effects considered as variable parameters in a successful simulation of the magnetic data. Compounds 2&amp;ndash;4 exhibit also weak intramolecular antiferromagnetic interactions (J) covering the range - 0.60(1) to - 1.50(1) cm- 1 with the Hamiltonian being defined as&lt;br /&gt;H = -JSReSM, M = Cu (2), Ni (3) and Co (4).&lt;/p&gt;</text>
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                <text>Polyhedron,&amp;nbsp;v. 208, 2021. -- e115414</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;span id="docs-internal-guid-e97ce1da-7fff-a760-ebfb-d30bbe0864e6"&gt;&lt;span&gt;10.1016/j.poly.2021.115414&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;The rod-shaped and Gram-stain-negative bacterial strain 16FT, isolated from an air sample collected at King George Island, maritime Antarctica, was investigated to determine its taxonomic status.&lt;br /&gt;Strain 16FT is strictly aerobic, catalase positive, oxidase positive and non-motile. Strain 16FT hydrolyses casein, lecithin, Tween 20, 60 and 80, but not aesculin, gelatin and starch. Growth of strain 16FT is observed at 0&amp;ndash;20 �C (optimum 10 �C), pH 5.0&amp;ndash;8.0 (optimum pH 6.0), and in the presence of 0&amp;ndash;2.0% NaCl (optimum 0.5%). The predominant menaquinone is MK-6, and the major fatty acids comprise anteiso-C15:0 and iso-C15:0. The major polar lipids are&lt;br /&gt;phosphatidylethanolamine, ornithine lipid OL2, unidentified phospholipid PL1 and the unidentified lipids L3 and L6 lacking functional groups. The DNA G ? C content based on the draft genome sequence is 32.3 mol%. Sequence analysis of the 16S rRNA gene indicates the highest similarity to Kaistella palustris&lt;br /&gt;3A10T (95.4%), Kaistella chaponensis Sa 1147-06 T&lt;br /&gt;(95.2%), Kaistella antarctica AT1013T (95.1%), Kaistella carnis NCTC 13525 T (95.1%) and below 95.0% to other species with validly published names. Phylogenetic analysis based on 16S rRNA gene and whole-genome sequences places strain 16FT in a distinct branch, indicating a separate lineage within the family Weeksellaceae. Based on the data from our polyphasic approach, 16FT represents a novel species of a new genus, for which the name Frigoriflavimonas asaccharolytica gen. nov, sp. nov. is proposed. The type strain is 16FT (= CCM 8975 T = CGMCC No.1.16844 T).&lt;/p&gt;</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Influence of the support and SnO2 content on the electrocatalytic properties of PdSn/C electrocatalysts for EOR in alkaline medium&amp;nbsp;&lt;/strong&gt;</text>
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                <text>&lt;p&gt;An in-house synthesized activated biocarbon (aBC) and commercial Vulcan carbon (V) were studied as PdSn catalyst&lt;br /&gt;supports for the ethanol oxidation reaction (EOR) in an alkaline medium. The results obtained showed that the PdSn/V&lt;br /&gt;electrocatalyst presented much higher catalytic performance than the PdSn/aBC. These results can be associated with the&lt;br /&gt;fact that the catalyst particles in the PdSn/V electrocatalyst presented a higher SnO2 concentration compared to PdSn/aBC. The presence of SnO2 has an electronic effect that accelerates the adsorption of ethanol on the surface of Pd, thus enhancing the ethanol oxidation kinetics and contributing to a significant improvement in the PdSn/V catalytic activity. However, nosignificant differences were observed in the EOR mechanism.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?5fa926816feec12a1150ae110081844c" target="_blank"&gt;&lt;strong&gt;Leal da Silva, Elen&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Cadorin, Martina&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Radtke, Claudio&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Castilho Rodrigues Siqueli, Aline&lt;/strong&gt;</text>
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                <text>Waste and Biomass Valorization, 2021.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;2-Mercaptomethyl thiazolidines (MMTZs) inhibit all Metallo-&amp;beta;- lactamase classes by maintaining a conserved binding mode&lt;/strong&gt;</text>
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                <text>&lt;p&gt;Metallo-&amp;beta;-lactamase (MBL) production in Gram-negative&lt;br /&gt;bacteria is an important contributor to &amp;beta;-lactam antibiotic&lt;br /&gt;resistance. Combining &amp;beta;-lactams with &amp;beta;-lactamase inhibitors (BLIs) is a validated route to overcoming resistance, but MBL inhibitors are not available in the clinic. On the basis of zinc utilization and sequence, MBLs are divided into three subclasses, B1, B2, and B3, whose differing active-site architectures hinder development of BLIs capable of &amp;ldquo;crossclass&amp;rdquo; MBL inhibition. We previously described 2-mercaptomethyl thiazolidines (MMTZs) as B1 MBL inhibitors (e.g., NDM-1) and here show that inhibition extends to the clinically relevant B2 (Sfh-I) and B3 (L1) enzymes. MMTZs inhibit purified MBLs in vitro (e.g., Sfh-I, Ki 0.16 &amp;mu;M) and potentiate &amp;beta;-lactam activity against producer strains. X-ray crystallography reveals that inhibition involves direct&lt;br /&gt;interaction of the MMTZ thiol with the mono- or dizinc centers of Sfh-I/L1, respectively. This is further enhanced by sulfur-&amp;pi;&lt;br /&gt;interactions with a conserved active site tryptophan. Computational studies reveal that the stereochemistry at chiral centers is critical, showing less potent MMTZ stereoisomers (up to 800-fold) as unable to replicate sulfur-&amp;pi; interactions in Sfh-I, largely through steric constraints in a compact active site. Furthermore, in silico replacement of the thiazolidine sulfur with oxygen (forming an oxazolidine) resulted in less favorable aromatic interactions with B2 MBLs, though the effect is less than that previously observed for the subclass B1 enzyme NDM-1. In the B3 enzyme L1, these effects are offset by additional MMTZ interactions with the protein main chain. MMTZs can therefore inhibit all MBL classes by maintaining conserved binding modes through different routes.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Hinchliffe, Philip&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Moreno, Diego M.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Rossi, Maria Agustina&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cvsni/?urlId=42fe119c34983a789c36c408f562cd5f77d193c08040c24e2c0dcd69721abe8668e45b666fbf9beae3ffd8a615c89500897f4f8242fac3b393c1234a61254446&amp;amp;convocatoria=21&amp;amp;formato=html" target="_blank"&gt;&lt;strong&gt;Martinez, Veronica&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?39341dbccf2067a2ebdf27cd39859aec" target="_blank"&gt;&lt;strong&gt;Villamil, Valentina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Spellberg, Brad&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Drusano, George L.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Banchio, Claudia&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?11f116dbdcd0917430c764781820c3ae07133f652f4972256dc46f54fda1a3fcf8ce8ef0955ba2079acd7eb19d1ee52d88035eacfdec3666f5e20b2b35381b70" target="_blank"&gt;&lt;strong&gt;Mahler, Graciela&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Bonomo, Robert A.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Vila, Alejandro J.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Spencer, James&lt;/strong&gt;</text>
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                <text>ACS Infectious Diseases,&amp;nbsp;v. 7, n&amp;deg; 9, 2021. -- pp. 2697-2706.</text>
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                <text>American Chemical Society</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;span id="docs-internal-guid-9b5a01a0-7fff-dbe8-dcb6-45516e3cf435"&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;span&gt;10.1021/acsinfecdis.1c00194&lt;/span&gt;&lt;/span&gt;</text>
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                  <text>Bibliografía Nacional Química</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                  <text>Departamento de Documentación y Biblioteca</text>
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                  <text>RIQUIM</text>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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                <text>&lt;strong&gt;Fe(III)-Complex-Imprinted polymers for the green oxidative degradation of the methyl orange dye pollutant&lt;/strong&gt;</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2021</text>
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                <text>&lt;p&gt;One of the biggest problems worldwide is the pollution of natural water bodies by dyes coming from effluents used in the textile industry. In the quest for novel effluent treatment alternatives, the aim of this work was to immobilize Fe(III) complexes in molecularly imprinted polymers (MIPs) to produce efficient Fenton-like heterogeneous catalysts for the green oxidative degradation of the methyl orange (MO) dye pollutant. Different metal complexes bearing commercial and low-cost&lt;br /&gt;ligands were assayed and their catalytic activity levels towards the discoloration of MO by H2O2 were assessed. The best candidates were Fe(III)-BMPA (BMPA = di-(2-picolyl)amine) and Fe(III)-NTP (NTP = 3,30,3&amp;rdquo;-nitrilotripropionic acid), displaying above 70% MO degradation in 3 h. Fe(III)-BMPA&lt;br /&gt;caused the oxidative degradation through two first-order stages, related to the formation of BMPAFe- OOH and the generation of reactive oxygen species. Only the first of these stages was detected for Fe(III)-NTP. Both complexes were then employed to imprint catalytic cavities into MIPs. The polymers showed catalytic profiles that were highly dependent on the crosslinking agent employed, with N,N-methylenebisacrylamide (MBAA) being the crosslinker that rendered polymers with optimal oxidative performance (&amp;gt;95% conversion). The obtained ion-imprinted polymers constitute cheap and robust solid matrices, with the potential to be coupled to dye-containing effluent treatment systems with synchronous H2O2 injection.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?4891bc251f76efde9a01116117d527c1" target="_blank"&gt;&lt;strong&gt;Haller, Paulina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?5c1ca4d55a5933a1752b3fc23d7cad09c4e5df59004aa474d3d272c7b6b5d79efe1957de15b2f0c75050b8d88b94dc89f36f3a8703836670d171bb4291eb6134" target="_blank"&gt;&lt;strong&gt;Machado, Ignacio&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?750e9b353a1a0eefb2ebafb09948ec8ad0aaf80f89b11beeaec5c09b63f96eaba9e18ada7bbd99aa41fb5465563fac0dc417bfd7ca15c0e1b30c90239c1b2ecb" target="_blank"&gt;&lt;strong&gt;Torres, Julia&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?4a66380a391f31c3cebb316911e1ebfd812f0fdb9e1d82ab7b2bdbaf01254ffd7849dfab6b129d8c0ae152068bb656dc52e516bb19f5ec21387308336faad237" target="_blank"&gt;&lt;strong&gt;Vila, Agustina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?5ad3267f4b4cb5190a6d9a3f5877923f528b6603e8a436c2005a31c5f35cd644629532a16ae958823cff6464fe03287baebd3b8724cc14f8d05da74957fe496d" target="_blank"&gt;&lt;strong&gt;Veiga, Nicol&amp;aacute;s&lt;/strong&gt;&lt;/a&gt;</text>
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              <elementText elementTextId="621596">
                <text>Polymers, v. 13, n&amp;deg; 18, 2021. -- e3127</text>
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                <text>MDPI</text>
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                <text>2021</text>
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            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="621599">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;Antibiotic resistance is a major threat to global public health. &amp;beta;-lactamases, which catalyze breakdown of &amp;beta;-lactam antibiotics, are a principal cause. Metallo &amp;beta;-lactamases (MBLs) represent a particular challenge because they hydrolyze almost all &amp;beta;-lactams and to date no MBL inhibitor has been approved for clinical use. Molecular simulations can aid drug discovery, for example, predicting inhibitor complexes, but empirical&lt;br /&gt;molecular mechanics (MM) methods often perform poorly for metalloproteins. Here we present a multiscale approach to model thiol inhibitor binding to IMP-1, a clinically important MBL containing two catalytic zinc ions, and predict the binding&lt;br /&gt;mode of a 2-mercaptomethyl thiazolidine (MMTZ) inhibitor. Inhibitors were first docked into the IMP-1 active site, testing different docking programs and scoring functions on multiple crystal structures. Complexes were then subjected to molecular&lt;br /&gt;dynamics (MD) simulations and subsequently refined through QM/MM optimization with a density functional theory (DFT) method, B3LYP/6-31G(d), increasing the accuracy of the method with successive steps. This workflow was tested on two IMP-1: MMTZ complexes, for which it reproduced crystallographically observed binding, and applied to predict the binding mode of a third MMTZ inhibitor for which a complex&lt;br /&gt;structure was crystallographically intractable. We also tested a 12-6-4 nonbonded interaction model in MD simulations and optimization with a SCC-DFTB QM/MM approach. The results show the limitations of empirical models for treating these systems and indicate the need for higher level calculations, for example, DFT/MM, for reliable structural predictions. This study demonstrates a reliable computational pipeline that can be applied to inhibitor design for MBLs and other zinc-metalloenzyme systems.&lt;/p&gt;</text>
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                <text>Proteins: Structure, Function, and Bioinformatics,&amp;nbsp;2021. -- pp. 1-13</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;In continuation our effort to research the chemical space of aryloxy-naphthoquinones as potential anti-Chagas agents, we synthesized nine derivatives and these compounds were evaluated in vitro against the epimastigote and trypomastigote forms of Mexican strains of Trypanosoma cruzi (T. cruzi). Most of these derivatives are highly active against epimastigote forms (IC50 &amp;lt; 1.0 &amp;mu;M) compared to the reference drug benznidazole (Bzn). Then these were evaluated on trypomastigotes, which is showing better potency results than Bzn for compounds 3b and 3g. In addition, the cytotoxicity of these compounds was determined on the murine macrophage cell line J774. 3b and 3i were the most selective compounds&lt;br /&gt;against NINOA trypomastigote and INC-5 epimastigote forms, respectively. Further these compounds also have good oral bioavailability according to theoretical predictions. Finally, we were able to determine optimal substitution patterns using pharmacophoric models. All these results are provided very useful structural information to continue our designing of naphthoquinone derivatives against T. cruzi.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Toledo, Sof&amp;iacute;a&lt;/strong&gt;</text>
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                <text>Medicinal Chemistry Research, 2021</text>
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                <text>&lt;strong&gt;Crystal structure and magnetic study of the complex salt [RuCp(PTA)2&amp;ndash;l-CN-1jC:2jN&amp;ndash;RuCp(PTA)2]- [Re(NO)Br4(EtOH)0.5(MeOH)0.5] /&lt;/strong&gt;</text>
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                <text>&lt;p&gt;A new RuII&amp;ndash;ReII complex salt, �-cyanido-�2C:N-bis[(�5-cyclopentadienyl)bis- (3,5,7 triazaphosphaadamantane -�P)ruthenium(II)]tetrabromido(ethanol/methanol-�O)nitrosylrhenate(II), [Ru(CN)(C5H5)2(C6H12N3P)4][ReBr4(NO)-&lt;br /&gt;(CH4O)0.5(C2H6O)0.5] or [RuCp(PTA)2&amp;ndash;�-CN&amp;ndash;1�C:2�2N-RuCp(PTA)2]-[Re(NO)Br4(EtOH)0.5(MeOH)0.5] (PTA = 3,5,7-triazaphosphaadamantane) was obtained and characterized by single-crystal X-ray diffraction, elemental analysis and infrared spectroscopy. The title salt was obtained by liquid&amp;ndash;liquid&lt;br /&gt;diffusion of methanol/DMSO solutions of (NBu4)[Re(NO)Br4(EtOH)] and[(PTA)2CpRu&amp;ndash;�-CN&amp;ndash;1�C:2�2N-RuCp(PTA)2](CF3SO3). The RuII and ReII independent moieties correspond to a binuclear and mononuclear complex ion, respectively. A deep geometrical parameter analysis was performed, and no significant differences were found with earlier reports containing similar molecules. The magnetic properties were investigated in the temperature range 2.0&amp;ndash;300 K, and the complex behaves as a quasi-magnetically isolated spin doublet with weak antiferromagnetic interactions.&lt;/p&gt;</text>
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                <text>Acta Crystallographica Section E: Crystallographic Communications,&amp;nbsp;v. 77, 2021. -- pp. 749-754.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;p&gt;Classic acetyl thioester protection/deprotection methodologies are widely used in organic synthesis, but deprotection step usually requires harsh conditions not suitable for labile substrates. In this work, a new method for thioester deprotection using a thiotransesterification approach is described. Firstly, thioglycolic acid (TGA) was identified as a good deprotecting reagent in solution. In order to develop a thiol polymer-supported reagent, TGA was anchored to a PEG-based resin through an amide bond (TG-NCOSH).&lt;br /&gt;Both homogeneous and heterogeneous approaches were conveniently carried out at room temperature, in aqueous buffer at pH 8. The mild conditions were suitable for alkyl and phenyl thioesters. Moreover labile thioesters containing thiazolidine and oxazolidine scaffolds, bearing amine, ester and&lt;br /&gt;acetal functionalities were also deprotected. The polymer-supported TGA gave better deprotection yields compared to TGA in solution, yields ranging from 61 to 90%. The feasibility of the recovery and reuse of TG-NCO-SH reagent was explored, showing it can be reused at least five times without lossing the&lt;br /&gt;activity.&lt;/p&gt;</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;CATA (check-all-that-apply) questions enjoy high popularity for sensory product characterization with consumers. Amidst extensive methodological characterization, the meaning of term citation frequency has received modest attention only,&lt;br /&gt;possibly hindering further uptake. The present research performed a more detailed exploration of the relationship between CATA responses and perceived intensity of sensory attributes. In addition, the following question was addressed:&lt;br /&gt;How many consumers are necessary to interpret differences in CATA citation proportions as a proxy of differences in perceived intensity? The present research includes new empirical data from four consumer studies conducted in New Zealand and China under central location test conditions and a re-analysis of&lt;br /&gt;one consumer study. When dealing with samples with clear differences, the percentage of consumers selecting a sensory term for describing samples tended to be linearly correlated to average intensity ratings. A median of 15 consumers was&lt;br /&gt;needed for CATA to show good linear correlations with average intensity ratings, and the minimum number of consumers needed to reach the threshold for a good correlation was generally lower than 30.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?e13bee77c03cddbef59b397e314055a6622de73c70417f3162757bfad754bfa8ad01125204736ed535ca050230cfa514a6e43d3d2464b7fea2cb77f4995d0c4b" target="_blank"&gt;&lt;strong&gt;Vidal, Leticia&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Journal of Sensory Studies,&amp;nbsp;v. 36, N&amp;deg; 5, 2021. -- pp. 1-8</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;A simple composite scheme is presented and benchmarked against the 38 reactions in Truhlar's HTBH38/08 and NHTBH38/08 databases. Mean unsigned deviation&lt;br /&gt;(MUD) for the complete set of 68 independent barriers is 0.40 kcal mol-1, compared to 1.31 kcal mol-1 for G4 and 1.62 kcal mol-1 for the M06-2X-D3 method. The MUD of the new scheme on the barriers in the DBH24/08 subset (12 out of the 38&lt;br /&gt;reactions in the other sets) is 0.27 kcal mol-1, better than that obtained at the expensive CCSD(T,full)/aug-cc-pCV(T+d)Z level (0.46 kcal mol-1) and comparable to the most exact (and costly) Wn calculations (MUD = 0.14 kcal mol-1). The method was further tested against a subset of reactions, for which the geometry and energies of all species were determined at the much more demanding CCSD(T)-F12//pVQZ-F12 level. The SVECV-f12 procedure on this database results in RMSE and MUD values of only 0.21 and 0.16 kcal mol-1.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?a7868d1a46654e7a04ba7167141502086fa0cfad8b13463f75d90af715685994bc8f3eafaad6f6d2f6647277c9782143df93695c8a7d8e14295323ca2e2847d3" target="_blank"&gt;&lt;strong&gt;Ventura, Oscar N.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?3b42b7e942dfb5f7df70519237eaaff6c2386ae787c326a44ea0b3fd7743a688179c666dcbaf076a09d0b0b9dd9a085c7d061a8ec6f0e53bdd5460731aa560b2" target="_blank"&gt;&lt;strong&gt;Kieninger, Martina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?9820276cf16af85d33b82163df7cb1c9c0b2ac718050062d216ef9983705ded94bd9fe0d6f77a4367a0b189c0dfbaf46eaf78ae3d8b36e38799312bcc9c3950f" target="_blank"&gt;&lt;strong&gt;Katz, Aline&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?672abfaee668d8143a7b356856ae2d1b3876cb1cb1c28383aef4dbd8dbc4cdfa469351307b069733b0b4f90bb0616b9bcaaad88bf8c2b817274a4dc98aa1ae9a" target="_blank"&gt;&lt;strong&gt;Vega Teijido, Mauricio&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?b91c406aeb51fdd23183363e0573b5c98e5aba93ce6a3d6a23fbff94f65e632f4cbfbfef3dfef31ceb6dcb3244c892f2632afa50f0f6c7f729346ce8aa435d14" target="_blank"&gt;&lt;strong&gt;Segovia, Marc&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Irving, Kenneth&lt;/strong&gt;</text>
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                <text>International Journal of Quantum Chemistry,&amp;nbsp;v. 121, n&amp;deg; 18, 2021. -- pp. 1-19. -- e26745</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
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                <text>&lt;p dir="ltr"&gt;&lt;span&gt;10.1002/qua.26745&amp;nbsp;&lt;/span&gt;&lt;/p&gt;&#13;
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