<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/">
<rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5970">
    <dcterms:title><![CDATA[<strong>An&aacute;lisis arqueom&eacute;trico de pigmentos del sitio arqueol&oacute;gico Tambo Colorado por difracci&oacute;n de rayos X sincrotr&oacute;n</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PIGMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ARQUEOLOGIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[DIFRACCION DE RAYOS X]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANALISIS ARQUEOMETRICO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[A pesar de la excepcional arquitectura y policrom&iacute;a del sitio arqueol&oacute;gico de Tambo Colorado, no ha habido trabajos de conservaci&oacute;n ni en las estructuras arquitect&oacute;nicas de tierra cruda, ni en las superficies. Estos trabajos requieren una comprensi&oacute;n adecuada del estado de conservaci&oacute;n de la arquitectura del sitio y el an&aacute;lisis de los materiales utilizados. Con este prop&oacute;sito, los resultados del presente estudio pretenden explicar la naturaleza de los materiales (pigmentos) utilizados en las pinturas murales, as&iacute; como determinar las fuentes de estos materiales (canteras). Para ello, pigmentos de cantera fueron investigados por la t&eacute;cnica de difracci&oacute;n de rayos X, usando radiaci&oacute;n sincrotr&oacute;n, y refinamiento estructural por el m&eacute;todo de Rietveld. Se determin&oacute; la composici&oacute;n de los pigmentos, identificando las fases de anortita, hematita, cuarzo, clorita, halita, yeso, ortoclasa, illita, jarosita, calcita, caolinita, zinwaldita, cristobalita, anhidrita y albita. El refinamiento Rietveld confirm&oacute; la presencia de estas fases y determin&oacute; el porcentaje en peso de cada una de ellas.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Zeballos Vel&aacute;squez, Elvira</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wright, V&eacute;ronique</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=a6f6b983eb02f40fe8e9784a71115fd267d30ff3d5997288d688b4c247e99d4e992cc6c5f422970aefe50e0211ce803a6f4322d3eda65e95887a20dd9a4e39fd&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Suescun, Leopoldo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Asto, Esteban</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Revista Materia&nbsp; v. 24, no. 1, 2019. --p. 1-8.--e12321]]></dcterms:source>
    <dcterms:publisher><![CDATA[Laborat&oacute;rio de Hidrog&ecirc;nio PEMM/COPPE/UFRJ]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&egrave;s]]></dcterms:language>
    <dcterms:type><![CDATA[Artículo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1590/s1517-707620190001.0604]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5971">
    <dcterms:title><![CDATA[<strong>Does message framing matter for promoting the use of nutritional warnings in decision making?</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[INFORMACION NUTRICIONAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[POLITICAS PUBLICAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ETIQUETADO]]></dcterms:subject>
    <dcterms:subject><![CDATA[ETIQUETAS DE ADVERTENCIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[OBJECTIVE: To evaluate the impact of message framing on attitudes towards messages aimed at promoting the use of nutritional warnings, behavioural intention and actual behaviour, evaluated through visual attention to nutritional warnings and the choice of a snack product during a real choice task. DESIGN: Following a between-subjects design, participants were exposed to loss-framed nutrition messages, gain-framed nutrition messages or non-nutrition-related messages (control group). After evaluating the messages, participants were asked to select a snack product as a compensation for their participation. The experiment was conducted using an eye tracker. SETTING: Montevideo (Uruguay). PARTICIPANTS: Convenience sample of 201 people (18-51 years old, 58 % female). RESULTS: The average percentage of participants who fixated their gaze on the nutritional warnings during the choice task was slightly but significantly higher for participants who attended to nutrition messages (regardless of their framing) compared with the control group. Participants who attended to loss-framed messages fixated their gaze on the warnings for the longest period of time. In addition, the healthfulness of the snack choices was higher for participants exposed to nutrition-related messages compared with the control group. CONCLUSIONS: Results from the present work suggest that nutrition messages aimed at increasing awareness of nutritional warnings may increase consumers' visual attention and encourage more heathful choices. The framing of the messages only had a minor effect on their efficacy.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Vidal, Gabriela</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mach&iacute;n, Leandro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Aschemann-Witzel, Jessica</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiUu6uN17_mAhWcEbkGHZWqAO8QFjAAegQIBBAE&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3De41ee09b825f22635cb8a1e9b42b334d75d1c2be0ccaad4f086d148a0ebac442b4a82cfb05ef977a8fe31965e28ee4bb8889f1ccb549f56f20a9403e2c02a0cf%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw2b6EcmcyrtNMCI5VJlC4Az" target="_self"><strong>Ares, Gast&oacute;n.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Public Health Nutrition v. 22, no. 16, 2019. -- p. 3025-3034]]></dcterms:source>
    <dcterms:publisher><![CDATA[Cambridge University Press]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1017/S1368980019002507]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5972">
    <dcterms:title><![CDATA[<strong>Structural characterisation of new immunoadjuvant saponins from leaves and the first study of saponins from the bark of Quillaja brasiliensis by liquid chromatography electrospray ionisation ion trap mass spectrometry</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[SAPONINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANALISIS DE MONOSACARIDOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESPECTROMETRIA DE MASAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[QUILLAJA BRASILIENSIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Introduction Quillaja brasiliensis (St. A. ‐Hil. &amp; Tul) Mart (Quillajaceae) is a species native to South America, which is rich in saponins. Saponins are used in different industries, so there is a constant demand for this type of compound. Based on the wide range of applications for the saponins found in this species, notably as immunoadjuvants, we conducted a comprehensive study of this tree and its saponins. Objective The purpose of this work is to complete the characterisation of the immunoadjuvant saponin fraction from Q. brasiliensis leaves and further study the saponin fraction obtained from Q. brasiliensis bark. Methodology Saponin fractions were studied using mass spectrometry in combination with classical methods of monosaccharide and methylation analysis. We performed direct infusion and liquid chromatography/electrospray ionisation ion trap multiple‐stage mass spectrometry (DI‐ESI‐IT‐MSn and LC‐ESI‐IT‐MS2). Results Seventy‐five saponins, 21 from leaves and 54 from bark, were tentatively identified according to their molecular mass, fragmentation pattern and chromatographic behaviour. This work represents the first investigation of saponins from the bark of Q. brasiliensis and some of them presented new structural motifs not previously reported in the genus Quillaja. Conclusion The efficiency and selectivity of the data dependent LC‐MS2 method allowed the rapid profiling of saponins from Q. brasiliensis. The results of the monosaccharide and methylation analysis performed in saponins from Q. brasiliensis fractions and Q. saponaria Molina (Quillajaceae) fraction gives further support to the structures proposed according to the mass spectral data, validating the strategy used in the present work.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Wallace, Federico</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bennadji, Zohra</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiGk83Y3L_mAhVuIbkGHbYXCOwQFjAAegQIAxAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D83599915c2932d7ab87a1eb547042501ece38f26e6163f01a8a8aa642db67da505e5a1cb01f616571f4202b7d0c69a4823a7bdd022d839b2ff14f463b04195b3%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw1XjRVBgSdzxxVH1EdfAlFh" target="_self"><strong>Ferreira, Fernando.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Olivaro, Cristina</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Phytochemical Analysis v. 30, no.6, 2019. -- p. 644-652]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1002/pca.2837]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5973">
    <dcterms:title><![CDATA[<strong>Online pre-laboratory tools for first-year undergraduate chemistry course in Uruguay : student preferences and implications on student performance</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ENSE&Ntilde;ANZA]]></dcterms:subject>
    <dcterms:subject><![CDATA[RENDIMIENTO ESTUDIANTIL]]></dcterms:subject>
    <dcterms:subject><![CDATA[URUGUAY]]></dcterms:subject>
    <dcterms:subject><![CDATA[CURSO DE PREGRADO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[As a fundamental part of their chemical education, first-year undergraduate students are substantially involved in laboratory activities. Despite the specific teaching staff choices on the main laboratory aims, students normally receive a vast amount of information during these activities. Apart from understanding theoretical content, fundamental skills such as manipulation, data collection and interpretation should be developed. In this context, learners could feel overwhelmed since they can only process a few pieces of information at a time. Indeed, our experience at the Universidad de la Rep&uacute;blica (Uruguayan public university) shows that many first-year students are in fact not able to cope with all the information they receive during laboratory activities. As a result, many of them only follow the experimental protocol automatically, without gaining significant knowledge or developing the necessary skills. In this work, we assessed the use of new online interactive pre-laboratory activities implemented for 252 first-year university students enrolled in a 12-module General Chemistry laboratory course. The student choice of interactive versus more traditional material was evaluated together with observed preferences regarding the different interactive tools offered. Besides, an online pre-laboratory discussion forum was also implemented and assessed. Both the interactive material and the discussion forum were chosen freely by the majority of students (61% and 79%, respectively). Interestingly, the choice was to some extent modulated by student previous performance. Interactive pre-laboratory material was more frequently chosen by low previous performance students, whereas pre-laboratory forum was preferentially used by high previous performance students. Finally, the influence of these new materials on student laboratory performance was statistically analyzed. Other personal and academic variables were also taken into account. Interactive material access was positively correlated with the final laboratory marks for medium previous performance learners. On the other hand, for lower previous performance students, the academic discussion between teachers and partners promoted by the online forum was positively correlated with their academic performance.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="Veiga,%20Nicol&aacute;s%20https://exportcvuy.anii.org.uy/CvEstatico/?urlId=5ad3267f4b4cb5190a6d9a3f5877923f528b6603e8a436c2005a31c5f35cd644629532a16ae958823cff6464fe03287baebd3b8724cc14f8d05da74957fe496d&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Veiga, Nicol&aacute;s</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Luzardo, Florencia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Irving, Kenneth</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwjg1uvf57_mAhUbHbkGHZ3QDX8QFjAAegQIBRAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3Da76978aac0adea0e9091a69c13f1012ce9a1e8822b0a3b1b45ae8df4b552da5d211a38071d123c36e3b63c69180af51fa4ce5b9aade70e2dd5df76d76cb62989%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw1aRv5EyfAOeFqKW5i4fuHX" target="_self"><strong>Rodr&iacute;guez Ay&aacute;n, Mar&iacute;a Noel.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=750e9b353a1a0eefb2ebafb09948ec8ad0aaf80f89b11beeaec5c09b63f96eaba9e18ada7bbd99aa41fb5465563fac0dc417bfd7ca15c0e1b30c90239c1b2ecb&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Torres, Julia</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chemistry Education Research and Practice v. 20, no. 1, 2019. -- p. 229-245]]></dcterms:source>
    <dcterms:publisher><![CDATA[Royal Society of Chemistry]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ing&egrave;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1039/C8RP00204E]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5974">
    <dcterms:title><![CDATA[<strong>Development and evaluation of a 99mTc(V)-nitrido complex derived from estradiol for breast cancer imaging</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ESTROGENOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[TECNECIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[CANCER DE MAMA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESTROGENOS-RECEPTORES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[As a fundamental part of their chemical education, first-year undergraduate students are substantially involved in laboratory activities. Despite the specific teaching staff choices on the main laboratory aims, students normally receive a vast amount of information during these activities. Apart from understanding theoretical content, fundamental skills such as manipulation, data collection and interpretation should be developed. In this context, learners could feel overwhelmed since they can only process a few pieces of information at a time. Indeed, our experience at the Universidad de la Rep&uacute;blica (Uruguayan public university) shows that many first-year students are in fact not able to cope with all the information they receive during laboratory activities. As a result, many of them only follow the experimental protocol automatically, without gaining significant knowledge or developing the necessary skills. In this work, we assessed the use of new online interactive pre-laboratory activities implemented for 252 first-year university students enrolled in a 12-module General Chemistry laboratory course. The student choice of interactive versus more traditional material was evaluated together with observed preferences regarding the different interactive tools offered. Besides, an online pre-laboratory discussion forum was also implemented and assessed. Both the interactive material and the discussion forum were chosen freely by the majority of students (61% and 79%, respectively). Interestingly, the choice was to some extent modulated by student previous performance. Interactive pre-laboratory material was more frequently chosen by low previous performance students, whereas pre-laboratory forum was preferentially used by high previous performance students. Finally, the influence of these new materials on student laboratory performance was statistically analyzed. Other personal and academic variables were also taken into account. Interactive material access was positively correlated with the final laboratory marks for medium previous performance learners. On the other hand, for lower previous performance students, the academic discussion between teachers and partners promoted by the online forum was positively correlated with their academic performance.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Tejer&iacute;a, Emilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=2&amp;ved=2ahUKEwi9y_Pd3b_mAhWHIbkGHY0LA4AQFjABegQIBRAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D44fdd0a91803ce0502eee9f4ffadef292fcbecefdc292eac0c76afbdce088c91cd8be39ea544d8e9e9dbafc0d21627b25fe4e21ceccb4fe0015cc1e361df511f%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw3n-yKijxCG7ZXzNdNZaGK2" target="_self"><strong>Giglio, Javier</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fern&aacute;ndez, Leticia.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiXraqg57_mAhWeDrkGHY_XCY8QFjAAegQIBBAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3Dea7cf9391caf5c3b3ad7a354aba47fe929d27dad6170b5a2afe0aba2c5c3d8f3f172551a6091ced17d399e33814eb2648c775b9a3979d424ff3d2c4efd990ec3%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw2B_qXBayHY0fd_Eg2W9sgq" target="_self"><strong>Rey, Ana.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Applied Radiation and Isotopes v. 154, 2019.-- p. 1-8.--e108854]]></dcterms:source>
    <dcterms:publisher><![CDATA[Royal Society of Chemistry]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1039/C8RP00204E]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5975">
    <dcterms:title><![CDATA[Structure and specificity of several triclocarban-binding single domain camelid antibody fragments]]></dcterms:title>
    <dcterms:subject><![CDATA[NANOCUERPOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESTRUCTURA CRISTALINA]]></dcterms:subject>
    <dcterms:subject><![CDATA[TRICLOCARBAN]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The variable VHH domains of camelid single chain antibodies have been useful in numerous biotechnology applications due to their simplicity, biophysical properties, and abilities to bind to their cognate antigens with high affinities and specificity. Their interactions with proteins have been well-studied, but considerably less work has been done to characterize their ability to bind haptens. A high-resolution structural study of three nanobodies (T4, T9, and T10) which have been shown to bind triclocarban (TCC, 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea) with near-nanomolar affinity shows that binding occurs in a tunnel largely formed by CDR1 rather than a surface or lateral binding mode seen in other nanobody-hapten interactions. Additional significant interactions are formed with a non-hypervariable loop, sometimes dubbed "CDR4". A comparison of apo and holo forms of T9 and T10 shows that the binding site undergoes little conformational change upon binding of TCC. Structures of three nanobody-TCC complexes demonstrated there was not a standard binding mode. T4 and T9 have a high degree of sequence identity and bind the hapten in a nearly identical manner, while the more divergent T10 binds TCC in a slightly displaced orientation with the urea moiety rotated approximately 180&deg; along the long axis of the molecule. In addition to methotrexate, this is the second report of haptens binding in a tunnel formed by CDR1, suggesting that compounds with similar hydrophobicity and shape could be recognized by nanobodies in analogous fashion. Structure-guided mutations failed to improve binding affinity for T4 and T9 underscoring the high degree of natural optimization.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Tabares da Rosa, Sof&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wogulis, Linda A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wogulis, Mark D.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=f843e2759f6ee96f8a16e51ceccfaeb41eb83154ba5da266ce35c9e64d7ad49b7ee8622e336b48ac9846dbe51b76b49fb1d2738fdaf473a4c75dea6e4f1afd20&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Gonz&aacute;lez Sapienza, Gualberto.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wilson, David K.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Molecular Recognition v. 32, no. 1, 2019. -- p. 1-9.--e2755]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1002/jmr.2755]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5977">
    <dcterms:title><![CDATA[<strong>Multiple Introductions of Tomato Pathogen Clavibacter michiganensis subsp. michiganensis into Iran as Revealed by a Global-Scale Phylogeographic Analysis</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[TOMATE]]></dcterms:subject>
    <dcterms:subject><![CDATA[AGENTES PATOGENOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[IRAN]]></dcterms:subject>
    <dcterms:subject><![CDATA[CULTIVOS SOLANACEOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[CLAVIBACTER MICHIGANENSIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Tomato bacterial canker caused by Clavibacter michiganensis subsp. michiganensis is one of the most important seed-borne tomato diseases around the globe. The disease was initially reported in 1993 in Iran, and it became a rising threat for the multibillion dollar tomato industry of the country during the last decade. In this study, using phylogeographic analyses, we determined genetic diversity and geographic distribution of C. michiganensis subsp. michiganensis in Iran. Our field surveys showed that the pathogen is expanding into the southern and eastern areas of the country. Furthermore, multilocus sequence analysis and typing (MLSA/MLST) using the sequences of five housekeeping genes (atpD, gyrB, ppk, recA, and rpoB) revealed that 37 C. michiganensis subsp. michiganensis strains isolated in Iran had high genetic diversity and placed in 15 sequence types (STs), while all the available 184 worldwide C. michiganensis subsp. michiganensis sequences were placed in 43 STs. MLSA divided the worldwide C. michiganensis subsp. michiganensis strains into two phylogroups (I and II). Among the 37 strains isolated in Iran, 30 strains clustered in phylogroup I, while 7 strains clustered in phylogroup II. Phylogeographic data inferred from the allelic profile of the five housekeeping genes suggested multiple introductions of C. michiganensis subsp. michiganensis inoculum into Iran, while the geographic origin of the Iranian C. michiganensis subsp. michiganensis strains remains undetermined. Further analyses using higher numbers of strains are warranted to decipher the evolutionary history of C. michiganensis subsp. michiganensis in Iran. Additionally, stricter seed/transplant inspections are recommended to reduce the risk of pathogen expansion to areas with no history of the disease]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Ansari, Maryam</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Taghavi, S. Mohsen</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Hamzehzarghani, Habiballah</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Valenzuela, Myryam</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Siri, Mar&iacute;a In&eacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Osdaghi, Ebrahim</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Applied and Environmental Microbiology v. 85, no. 24, 2019. -- e02098-19]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Society for Microbiology]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1128/AEM.02098-19]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5978">
    <dcterms:title><![CDATA[<strong>Chemoenzymatic Total Synthesis and Structural Revision of Ampelomins B, D, E, and epi-ampelomin B</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[SINTESIS QUIMIOENZIMATICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[AMPELOMINS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Enantioselective synthesis of ampelomin B and epi-ampelomin B, D, and E was accomplished starting from toluene, through a chemoenzymatic sequence, in which stereoselective hydrogenation, Mitsunobu reaction, and regio- and stereoselective nucleophilic opening of an epoxide were used as the main transformations. Structural revision and absolute configuration of the natural compounds were carried out.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Brindisi, Carolina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>V&aacute;zquez, Silvana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=a6f6b983eb02f40fe8e9784a71115fd267d30ff3d5997288d688b4c247e99d4e992cc6c5f422970aefe50e0211ce803a6f4322d3eda65e95887a20dd9a4e39fd&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Suescun, Leopoldo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=cbfccfdb54596e6cb04c5c403027fe4eababcb01435d93575e63367c06474cc7c5897f2b080448c7cf73d21a359e87a044d9cc552bdb2f20cedca29dba1930fd&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Seoane, Gustavo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Sotero Mart&iacute;n, V&iacute;ctor</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Brovetto, Margarita</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Organic Chemistry v. 84, no. 24, 2019. -- p. 15997-16002]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Chemical Society]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1021/acs.joc.9b02472]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5979">
    <dcterms:title><![CDATA[<strong>Theoretical investigation of various aspects of two dimensional holey boroxine, B3O3</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[BERILIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BORO]]></dcterms:subject>
    <dcterms:subject><![CDATA[PROPIEDADES ELECTRICAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PROPIEDADES ELECTRONICAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PROPIEDADES OPTICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[INVESTIGACION TEORICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[By means of first-principles calculations, we study the structural, electronic and mechanical properties of the newly synthesized boron&ndash;oxygen holey framework (Chem. Comm. 2018, 54, 3971). It has a planar structure formed by B3O3 hexagons, which are joined via strong covalent boron&ndash;boron bonds. The six B3O3 units are connected with six-fold symmetry exhibiting a large hole with a surface area of 23 &Aring;2, which is ideal for the adsorption of alkalis. For neutral alkalis, we found that the adsorption energy of potassium is 14 and 12 kcal mol&minus;1 larger than those determined for sodium and lithium, respectively. In contrast, for alkali cations, there is a clear preference for lithium over sodium and potassium. With regard to its electronic properties, it is an insulator with an electronic band gap of 5.3 eV, at the HSE level of theory. We further investigate the effect of strain on the band gap and find it a less efficient technique to tune the electronic properties. The wide optical gap of B3O3 can be utilized in ultraviolet (UV) applications, such as UV photodetectors, etc. Additionally, the 2D elastic modulus of B3O3 (53.9 N m&minus;1) is larger than that of Be3N2, silicene, and germanene. Besides, we also report bilayer and graphite-like bulk B3O3 and furthermore, find that the optoelectronic properties of the bilayer can be tuned with an external electric field. The great tunability of optical properties from UV to the visible range offers a vast range of applications in optoelectronics.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwjAzt352r_mAhUBErkGHSG_ALIQFjAAegQIBBAG&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2Fcv%2F%3F5838628233fef1a83df67e2235d927c4a69fd08d7b3b2cbd45f825b3b0327f2f869df055be96ee401aec1ab3995b9905c1339dbf8b5b1059582d0221c61fa4ea&amp;usg=AOvVaw1-3bMhJ1paRert553HzPBB" target="_self"><strong>Denis, Pablo A.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ullah, Saif<br /></strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Sato, Fernando</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[RSC Advances v. 9, no. 64, 2019. -- p. 37526-37536]]></dcterms:source>
    <dcterms:publisher><![CDATA[Royal Society of Chemistry]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1039/C9RA07338H]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5980">
    <dcterms:title><![CDATA[<strong>99mTc labelling strategies for the development of potential nitroimidazolic hypoxia imaging agents</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[TECNECIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[HIPOXIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESTRATEGIAS DE ETIQUETADO]]></dcterms:subject>
    <dcterms:subject><![CDATA[NITROIMIDAZOLES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Technetium-99m has a rich coordination chemistry that offers many possibilities in terms of oxidation states and donor atom sets. Modifications in the structure of the technetium complexes could be very useful for fine tuning the physicochemical and biological properties of potential 99mTc radiopharmaceuticals. However, systematic study of the influence of the labelling strategy on the &ldquo;in vitro&rdquo; and &ldquo;in vivo&rdquo; behaviour is necessary for a rational design of radiopharmaceuticals. Herein we present a review of the influence of the Tc complexes&rsquo; molecular structure on the biodistribution and the interaction with the biological target of potential nitroimidazolic hypoxia imaging radiopharmaceuticals presented in the literature from 2010 to the present. Comparison with the gold standard [18F]Fluoromisonidazole (FMISO) is also presented]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=2&amp;ved=2ahUKEwi9y_Pd3b_mAhWHIbkGHY0LA4AQFjABegQIBRAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D44fdd0a91803ce0502eee9f4ffadef292fcbecefdc292eac0c76afbdce088c91cd8be39ea544d8e9e9dbafc0d21627b25fe4e21ceccb4fe0015cc1e361df511f%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw3n-yKijxCG7ZXzNdNZaGK2" target="_self"><strong>Giglio, Javier</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiXraqg57_mAhWeDrkGHY_XCY8QFjAAegQIBBAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3Dea7cf9391caf5c3b3ad7a354aba47fe929d27dad6170b5a2afe0aba2c5c3d8f3f172551a6091ced17d399e33814eb2648c775b9a3979d424ff3d2c4efd990ec3%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw2B_qXBayHY0fd_Eg2W9sgq" target="_self"><strong>Rey, Ana.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Inorganics v. 7, no. 11, 2019.-- p. 1-16.--e7110128]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[Pdf]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.3390/inorganics7110128]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5981">
    <dcterms:title><![CDATA[<strong>Genomic and Transcriptomic Basis of Hanseniaspora vineae&rsquo;s Impact on Flavor Diversity and Wine Quality</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[VINO]]></dcterms:subject>
    <dcterms:subject><![CDATA[AROMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[GENOMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Hanseniaspora is the main genus of the apiculate yeast group that represents approximately 70% of the grape-associated microflora. Hanseniaspora vineae is emerging as a promising species for quality wine production compared to other non-Saccharomyces species. Wines produced by H. vineae with Saccharomyces cerevisiae consistently exhibit more intense fruity flavors and complexity than wines produced by S. cerevisiae alone. In this work, genome sequencing, assembling, and phylogenetic analysis of two strains of H. vineae showed that it is a member of the Saccharomyces complex and it diverged before the whole-genome duplication (WGD) event from this clade. Specific flavor gene duplications and absences were identified in the H. vineae genome compared to 14 fully sequenced industrial S. cerevisiae genomes. The increased formation of 2-phenylethyl acetate and phenylpropanoids such as 2-phenylethyl and benzyl alcohols might be explained by gene duplications of H. vineae aromatic amino acid aminotransferases (ARO8 and ARO9) and phenylpyruvate decarboxylases (ARO10). Transcriptome and aroma profiles under fermentation conditions confirmed these genes were highly expressed at the beginning of stationary phase coupled to the production of their related compounds. The extremely high level of acetate esters produced by H. vineae compared to that by S. cerevisiae is consistent with the identification of six novel proteins with alcohol acetyltransferase (AATase) domains. The absence of the branched-chain amino acid transaminases (BAT2) and acyl coenzyme A (acyl-CoA)/ethanol O-acyltransferases (EEB1) genes correlates with H. vineae's reduced production of branched-chain higher alcohols, fatty acids, and ethyl esters, respectively. Our study provides sustenance for understanding and potentially utilizing genes that determine fermentation aromas.IMPORTANCE The huge diversity of non-Saccharomyces yeasts in grapes is dominated by the apiculate genus Hanseniaspora Two native strains of Hanseniaspora vineae applied to winemaking because of their high oenological potential in aroma and fermentation performance were selected to obtain high-quality genomes. Here, we present a phylogenetic analysis and the complete transcriptome and aroma metabolome of H. vineae during three fermentation steps. This species produced significantly richer flavor compound diversity than Saccharomyces, including benzenoids, phenylpropanoids, and acetate-derived compounds. The identification of six proteins, different from S. cerevisiae ATF, with diverse acetyltransferase domains in H. vineae offers a relevant source of native genetic variants for this enzymatic activity. The discovery of benzenoid synthesis capacity in H. vineae provides a new eukaryotic model to dilucidate an alternative pathway to that catalyzed by plants' phenylalanine lyases.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Giorello, Facundo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Valera, Mar&iacute;a Jos&eacute;</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mart&iacute;n, Valentina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Parada, Andr&eacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Salzman, Valentina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Camesasca, Laura</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;ved=2ahUKEwjzqaOE3L_mAhUXLLkGHbwcC24QFjAAegQIAhAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2Fpdf%2F%3F00c29a1890f0577bb09e361a544f762be0bbd9e09ce10b07648d1aa42d8a501fd071c34f0d2d17ebfa5f6f43e41ffb0970132f4083555c3642df2f7104cba2d5&amp;usg=AOvVaw0ZtgFgAwuvYA3gehuRdjSS" target="_self"><strong>Fari&ntilde;a, Laura.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;ved=2ahUKEwi-va_z17_mAhVCGLkGHTXPBKYQFjAAegQIBBAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3De1ba7de0d572172f427d637a61cf7ffedcaca3f4642b955065a2f3a72fb70a03516776171609b3227f51a8c2647cd41dcfe25b5f501e985b684341e0de901a45%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw3UX_H--GFyqPfQlZgR1J2O" target="_self"><strong>Boido, Eduardo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=d6a1cbfc10da172897739e5ce2cd598a9ebd0b32367fb52f6620ef46bf5e081e8ec94156da4d088b9c5c631bdde95c723b8c88c525d75bd0a0e9875c775c0f92&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Medina, Karina</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Aguilar, Pablo S.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mas, Albert</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gaggero de Munno, Carina.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=8ccb5adf5e034ef96c0a125b78ad413aa3342b85ebd78407b9942af62fa2cbca3bb99b7ba8a494b83c813ecac54cfcd67c603a8f425ba0d9961d03d7c2f8d777&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Carrau, Francisco.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Applied and Environmental Microbiology v. 85, no. 1, 2019. -- p. 1-20. --e01959-18]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Society for Microbiology]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1128/AEM.01959-18]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5982">
    <dcterms:title><![CDATA[<strong>Biocontrol of Aspergillus flavus in Ensiled Sorghum by Water Kefir Microorganisms</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[SORGO]]></dcterms:subject>
    <dcterms:subject><![CDATA[MICROORGANISMOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[KEFIR DE AGUA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ASPERGILLUS FLAVUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The capacity of microorganisms from water kefir (WK) to control Aspergillus flavus growth during the aerobic phase of ensiled sorghum grains was determined. Sorghum inoculated with A. flavus was treated with filter-sterilized and non-sterilized water kefir, ensiled, and incubated 7 days at 25 &deg;C. A. flavus growth was quantified by qPCR after incubation. Mold growth was inhibited in the presence of water kefir while no inhibition was observed when filter-sterilized water kefir was applied, demonstrating the relevant role of the microorganisms in the kefir water in the biocontrol process. Fungal and bacterial diversity in treated sorghum mini-silos was analyzed by high-throughput sequencing. Firmicutes was the predominant bacterial phyla and Lactobacillus represented the most abundant genus, while Ascomycota was the predominant fungal phyla with Saccharomyces and Pichia as the major genera. Bacterial and yeast counts before and after incubation indicated that the microbial community obtained from WK was able to grow in the sorghum mini-silos in the presence of A. flavus. Results of the present work indicate that the use of a mixed inoculum of microorganisms present in WK may represent an alternative management practice to avoid the growth of A. flavus in ensiled sorghum grains and the concomitant contamination with aflatoxins.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Gonda, Mariana.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Garmendia, Gabriela.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rufo, Caterina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Le&oacute;n Pel&aacute;ez, Angela</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wisniewski, Michael</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Droby, Samir</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=513cd40ab0f7a3ae4d114f4a4e9dc877c410ad8f0bff71b7001257cfe95eca4576e784b3d7ba4a4ef9b56967d3205b0cb2adc6266bf6792221c2f2f8b5f7200e&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Vero, Silvana.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Microorganisms v. 7, no. 8, 2019. -- p. 1-18.--e253]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.3390/microorganisms7080253]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5983">
    <dcterms:title><![CDATA[<strong>Detection of oxytetracycline in honey using SERS on silver nanoparticles</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[MIEL]]></dcterms:subject>
    <dcterms:subject><![CDATA[OXITETRACICLINA]]></dcterms:subject>
    <dcterms:subject><![CDATA[NANOPARTICULAS DE PLATA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[In this work, we made a review about the application of Raman spectroscopy for quality control of honey and other food samples. Simultaneously, it was carried out a new research evaluating silver nanoparticles (AgNPs) obtained by green synthesis for detection of the antibiotic Oxytetracycline (OTC), through Surface Enhanced Raman Spectroscopy (SERS). Glucose was used as reducing and capping agent in the formation of AgNPs in alkaline media. The frequencies found, belonging to the antibiotic at 20, 15, 10 and 5 ppb, could be visibly differentiated from those corresponding to honey, being unnecessary to perform any extraction procedure or tedious manipulation of the sample. Theoretical frequencies were obtained by Density Functional Theory calculations and compared with the normal modes from SERS measures, founding an excellent agreement between them. The analysis shows a preference for the adsorption of OTC on silver cluster through oxygen atoms.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Gonz&aacute;lez F&aacute;, Alejandro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Pignanelli, Fernando</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>L&oacute;pez Corral, Ignacio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=2f2e59581473324400ee29ded741b9090cc25a893e73d02669ebfbc674c9e8b9b51bb30e2bca064dc7ebbd5c39aa3c844e86e507301e912aa1b0a5ae17423fa2&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Faccio, Ricardo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Juan, Alfredo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Di Nezio, Mar&iacute;a Susana</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Trends in Analytical Chemistry v. 121, 2019. -- p. 1-8.--e115673]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1016/j.trac.2019.115673]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5984">
    <dcterms:title><![CDATA[<strong>Optimization of culture conditions for the expression of three different insoluble proteins in Escherichia coli</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PROTEINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESCHERICHIA COLI]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[In this work, we made a review about the application of Raman spectroscopy for quality control of honey and other food samples. Simultaneously, it was carried out a new research evaluating silver nanoparticles (AgNPs) obtained by green synthesis for detection of the antibiotic Oxytetracycline (OTC), through Surface Enhanced Raman Spectroscopy (SERS). Glucose was used as reducing and capping agent in the formation of AgNPs in alkaline media. The frequencies found, belonging to the antibiotic at 20, 15, 10 and 5 ppb, could be visibly differentiated from those corresponding to honey, being unnecessary to perform any extraction procedure or tedious manipulation of the sample. Theoretical frequencies were obtained by Density Functional Theory calculations and compared with the normal modes from SERS measures, founding an excellent agreement between them. The analysis shows a preference for the adsorption of OTC on silver cluster through oxygen atoms.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Guti&eacute;rrez-Gonz&aacute;lez, Mat&iacute;as</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Far&iacute;as, Camila</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Tello, Samantha</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>P&eacute;rez-Etcheverry, Diana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Romero, Alfonso</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Zu&ntilde;iga, Roberto</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ribeiro, Carolina H.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lorenzo Ferreiro, Carmen</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Molina, Mar&iacute;a Carmen</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Scientific Reports v. 9, no. 1, 2019. --p. 1- 11. --e16850]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1016/j.trac.2019.115673]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5985">
    <dcterms:title><![CDATA[<strong>Effectiveness of micronizing zinc borate to improve its fungicidal properties</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[FUNGICIDAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BORATO DE ZINC]]></dcterms:subject>
    <dcterms:subject><![CDATA[LIXIVIACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The effectiveness was evaluated for an established wood preservative, zinc borate, prepared in an agitating bead mill to extensively reduce its particle size. The generated micro- or nano-particles of zinc borate were characterized by X-ray powder diffraction, and the particle size distribution was determined to evaluate the effect of milling. Then the fungicidal effectiveness of the zinc borate of both milled and unmilled samples were assayed against brown- and white-rot fungi, on culture medium and on conifer and hardwood as substrates. Treated wood samples were subjected to leaching tests. Scanning electron microscopic images of wood samples were examined to analyze the distribution of zinc borate within the wood. The micronized zinc product kept its crystal structure intact, and it increased the proportion of particles with diameters below 100 nm by 25% when compared to the unmilled product. Malt extract-agar medium supplemented with 2.5% of w/w milled and unmilled zinc borate inhibited fungal growth tested. Both milled and unmilled zinc borate protected the wood when not subjected to leaching. The milled sample of zinc borate improved resistance to leaching, which would allow its application in environments of high moisture content; however, it did not improve the fungicidal action against decay fungi.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Iba&ntilde;ez, Claudia M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Camargo, Alvaro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mantero, Carlos</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=2f2e59581473324400ee29ded741b9090cc25a893e73d02669ebfbc674c9e8b9b51bb30e2bca064dc7ebbd5c39aa3c844e86e507301e912aa1b0a5ae17423fa2&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Faccio, Ricardo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Malanga, Antonio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rabinovich, Mario</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[BioResources&nbsp; v. 14, no. 3, 2019.-- p. 6231-6246]]></dcterms:source>
    <dcterms:publisher><![CDATA[NC State University.]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1088/2053-1591/ab6636]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5986">
    <dcterms:title><![CDATA[<strong>Echinococcus granulosus : Insights into the protoscolex F-actin cytoskeleton</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ECHINOCOCCUS GRANULOSUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PROTOSCOLECES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Echinococcus granulosus is a cestode parasite whose cytoskeleton plasticity allows it to enter and develop inside its hosts, completing thus its life cycle. We focused our attention on F-actin organization and distribution in E. granulosus protoscoleces (PSC) in order to contribute to the knowledge of the parasite cytoskeleton. In particular, we addressed some aspects of F-actin rearrangements in PSC at different stages of the evagination/invagination process. The use of light microscopy allowed us to identify different PSC structures and phalloidin staining displayed a parasite's highly organized F-actin cytoskeleton. Suckers exhibit an important musculature composed of a set of radial fibers. At the rostellum, the F-actin filaments are arranged in a bulbar shape with perforations that appear to be the attachment places for the hooks. Also, "circular" structures of F-actin were identified, which remind the flame cells. Furthermore, parasite F-actin filaments, unevenly distributed, seem to have remained substantially unchanged during the evagination/invagination process. Finally, we showed that the scolex of an evaginated E. granulosus PSC reinvaginates in vitro without any treatment.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>La Rocca, Silvana.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Far&iacute;as, Joaquina.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Chalar G&oacute;mez, Cora Marta.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Kun, Alejandra E.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwik9eqw3L_mAhXcELkGHSDIC4sQFjAAegQIAhAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D48d014a909b15e26e8df9e70c4bf8bf43502b8d822b22f777f477f1c2bce3413b8aff40561f5b5c23014464c22337d3da58b15764cd7c0618c8b3fc58b546814%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw2QoGHPcdTGcFS20dtnkdj1" target="_self"><strong>Fern&aacute;ndez, Ver&oacute;nica.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Acta Tropica v. 199, 2019.--p. 1-7.--e105122]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1016/j.actatropica.2019.105122]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5987">
    <dcterms:title><![CDATA[<strong>Exploring the Exceptional Properties of Streptomyces : A Hands-On Discovery of Natural Products</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIINFECCIOSOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BACTERIAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PRODUCTOS NATURALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[STREPTOMYCES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Microbial biodiversity and its rich arsenal of natural products is an important and complex biological concept. We propose the use of Streptomyces, one of the most diverse bacterial genera and a major inhabitant of soil, as a model to explain the relevance and importance of this concept. Students will perform experiments ranging from isolation and selection of Streptomyces species, to performing fungal and bacterial challenge assays to evaluate their biocontrol capacity, to screening for specialized metabolic properties such as the production of lipases, amylases, and cellulases. Accompanied by active discussions on the experimental process and results, and integrated into the general microbiology curriculum, this real-life discovery-based lab exercise engages students in current topics concerning natural product discovery and reinforces their understanding of several important concepts in microbiology and biotechnology]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Lapaz, Mar&iacute;a In&eacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Juarez Cisneros, Estefan&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=efb831b99cdd223a96b51922929e18df47ecbb9eed05344f22f8000787a17aeab079309f3bc222deb569104171e98239bec9ba159d03cf5a69626efb7780904c&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Pianzzola, Mar&iacute;a Julia</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Francis, Isolde M.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[American Biology Teacher v. 81, no. 9, 2019. --p. 658-664]]></dcterms:source>
    <dcterms:publisher><![CDATA[National Association of Biology Teachers]]></dcterms:publisher>
    <dcterms:date><![CDATA[National Association of Biology Teachers]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[Pdf]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1525/abt.2019.81.9.658]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5988">
    <dcterms:title><![CDATA[<strong>Complex I and II Subunit Gene Duplications Provide Increased Fitness to Worms</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[HELMINTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[UBIQUINONA]]></dcterms:subject>
    <dcterms:subject><![CDATA[RODOQUINONA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Helminths use an alternative mitochondrial electron transport chain (ETC) under hypoxic conditions, such as those found in the gastrointestinal tract. In this alternative ETC, fumarate is the final electron acceptor and rhodoquinone (RQ) serves as an electron carrier. RQ receives electrons from reduced nicotinamide adenine dinucleotide through complex I and donates electrons to fumarate through complex II. In this latter reaction, complex II functions in the opposite direction to the conventional ETC (i.e., as fumarate reductase instead of succinate dehydrogenase). Studies in Ascaris suum indicate that this is possible due to changes in complex II, involving alternative succinate dehydrogenase (SDH) subunits SDHA and SDHD, derived from duplicated genes. We analyzed helminth genomes and found that distinct lineages have different gene duplications of complex II subunits (SDHA, SDHB, SDHC, and SDHD). Similarly, we found lineage-specific duplications in genes encoding complex I subunits that interact with quinones (NDUF2 and NDUF7). The phylogenetic analysis of ETC subunits revealed a complex history with independent evolutionary events involving gene duplications and losses. Our results indicated that there is not a common evolutionary event related to ETC subunit genes linked to RQ. The free-living nematode Caenorhabditis elegans uses RQ and has two genes encoding SDHA (sdha-1 and sdha-2) and two genes encoding NDUF2 (nduf2-1 and nduf2-2). sdha-1 and nduf2-1 are essential genes and have a similar expression pattern during C. elegans lifecycle. Using knockout strains, we found that sdha-2 and nduf2-2 are not essential, even in hypoxia. Yet, sdha-2 and nduf2-2 expression is increased in the early embryo and in dauer larvae, stages where there is low oxygen tension. Strikingly, sdha-1 and sdha-2 as well as nduf2-1 and nduf2-2 showed inverted expression profiles during the C. elegans life cycle. Finally, we found that sdha-2 and nduf2-2 knockout mutant strain progeny is affected. Our results indicate that different complex I and II subunit gene duplications provide increased fitness to worms.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiWovKM5b_mAhV0F7kGHQpxD50QFjAAegQIBBAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D6b87f435587181c154f1b47d1513697ca8585628b36ae67a82085df0df26bef79633f2f87a71609bd85aecc6c98033ecbdad25a883bb2c05df2b6f7a4bfd51d7%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw1cf_P5gsvAQsk4DkTqbHyE" target="_self"><strong>Otero Zubiaurre, Ana Luc&iacute;a</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mart&iacute;nez Rosales, Cecilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Barrera, Exequiel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Pantano, Sergio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=972518dae04cc6f1d53fd01909f7c2f4952184c3eedf364530afd35a4c507484cce1f86606ac8d829a37e89b7a9f837b6b0632e94efbaf9ba6abf23efe48f1dc&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Salinas, Gustavo.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Frontiers in Genetics v.10, 2019.--p. 1-10.--e1043]]></dcterms:source>
    <dcterms:publisher><![CDATA[Frontiers Media]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.3389/fgene.2019.01043]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5989">
    <dcterms:title><![CDATA[<strong>Silicon Carbide Induced Doping of Graphene : new Potential Synthetic Route for SiC3 Siligraphene</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[GRAFENO]]></dcterms:subject>
    <dcterms:subject><![CDATA[FERROMAGNETISMO]]></dcterms:subject>
    <dcterms:subject><![CDATA[SEMICONDUCTORES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The heteroatom doping of graphene is a useful method to amplify the outstanding properties of graphene. However, it is difficult to control the disposition of the dopants. By means of first-principles calculations, we show that the substrate-induced doping of epitaxial graphene leads to the formation of silicon doped graphene with a precise location of the dopants in the valley regions between crests. According to our results, in the valleys silicon dopants greatly prefer to replace the carbon atoms of the buffer layer which are bonded to the substrate by a large amount of energy. This selective doping suggests that a siligraphene layer in the g-SiC3 form would be an excellent model for a buffer layer grown on nanometer-sized areas of SiC, thus paving the way to the synthesis of a new two-dimensional material. We predict a stable antiferromagnetical (AF) ordering that behaves electronically as a semiconductor, degenerated with the highest ferromagnetic configuration of the system. A net magnetic moment of 0.65 &mu;B per Si dangling bond was found for both the AF and the most stable ferromagnetic state of the SiC-siligraphene system. Finally, we demonstrate that quasi-free-standing epitaxial siligraphene layers on 6H-SiC(0001) could be obtained by the intercalation of argon atoms. We expect that this work can motivate new experimental studies pursuing the synthesis of SiC3 siligraphene.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Pereyra Huelmo, Claudia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwjAzt352r_mAhUBErkGHSG_ALIQFjAAegQIBBAG&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2Fcv%2F%3F5838628233fef1a83df67e2235d927c4a69fd08d7b3b2cbd45f825b3b0327f2f869df055be96ee401aec1ab3995b9905c1339dbf8b5b1059582d0221c61fa4ea&amp;usg=AOvVaw1-3bMhJ1paRert553HzPBB" target="_self"><strong>Denis, Pablo A.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Physical Chemistry C v. 123, no. 50, 2019. -- p. 30341-30350]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Chemical Society]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1021/acs.jpcc.9b07978]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5990">
    <dcterms:title><![CDATA[<strong>Characterization of the effects involved in ultrasound-assisted extraction of trace elements from artichoke leaves and soybean seeds</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ALCACHOFAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[SEMILLAS DE SOJA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ULTRASONIDO]]></dcterms:subject>
    <dcterms:subject><![CDATA[ALIMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Ultrasonication is known to induce cavitation and can thus accelerate extraction, dissolution, digestion, and other processes, while the intense mixing caused by the propagation of ultrasound waves enhances analyte transfer to the extraction medium. Consequently, ultrasound-assisted extraction (UAE) is viewed as a simple procedure well suited for the extraction and subsequent determination of trace elements in food. Herein, we use different techniques to characterize several processes involved in probe- and bath-based UAE, apply them to the determination of trace metals (Cd, Cu, Ni, Pb, and Zn) in globe artichoke leaves and soybean seeds, and closely monitor the extraction rates of selected analytes. The developed UAE-based method is found to comply with the criteria of Green Chemistry and is concluded to be a reliable, simple, and cheap alternative to standard food analysis techniques.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong><a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=5c1ca4d55a5933a1752b3fc23d7cad09c4e5df59004aa474d3d272c7b6b5d79efe1957de15b2f0c75050b8d88b94dc89f36f3a8703836670d171bb4291eb6134&amp;formato=pdf&amp;convocatoria=21" target="_self">Machado, Ignacio</a></strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=2f2e59581473324400ee29ded741b9090cc25a893e73d02669ebfbc674c9e8b9b51bb30e2bca064dc7ebbd5c39aa3c844e86e507301e912aa1b0a5ae17423fa2&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Faccio, Ricardo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwjUpbHa5r_mAhXnK7kGHWGCAqYQFjAAegQIAhAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D61479bcedba0147d3c3d319c58b33c3b8097d0e921a472a96c977f72410c865c0f760872b9315b74ede8b43e4be18142c73316e553e66830ee9d5a4c2cfdd139%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw27Y3Lz3kXq6ufLaHD6Mkxc" target="_self"><strong>Pist&oacute;n, Mariela</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Ultrasonics - Sonochemistry 59&nbsp; v. 59, 2019. --p.1-7.--e104752]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1016/j.ultsonch.2019.104752]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5991">
    <dcterms:title><![CDATA[<strong>Particles from the Echinococcus granulosus Laminated Layer Inhibit CD40 Upregulation in Dendritic Cells by Interfering with Akt Activation</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[HELMINTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ECHINOCOCCUS GRANULOSUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The larval stage of the cestode Echinococcus granulosus causes cystic echinococcosis in humans and livestock. This larva is protected by the millimeter-thick, mucin-based laminated layer (LL), from which materials have to be shed to allow parasite growth. We previously reported that dendritic cells (DCs) respond to microscopic pieces of the mucin gel of the LL (pLL) with unconventional maturation phenotypes, in the absence or presence of Toll-like receptor (TLR) agonists, including lipopolysaccharide (LPS). We also reported that the presence of pLL inhibited the activating phosphorylation of the phosphatidylinositol 3-kinase (PI3K) effector Akt induced by granulocyte-macrophage colony-stimulating factor or interleukin-4. We now show that the inhibitory effect of pLL extends to LPS as a PI3K activator, and results in diminished phosphorylation of GSK3 downstream from Akt. Functionally, the inhibition of Akt and GSK3 phosphorylation are linked to the blunted upregulation of CD40, a major feature of the unconventional maturation phenotype. Paradoxically, all aspects of unconventional maturation induced by pLL depend on PI3K class I. Additional components of the phagocytic machinery are needed, but phagocytosis of pLL particles is not required. These observations hint at a DC response mechanism related to receptor-independent mechanisms proposed for certain crystalline and synthetic polymer-based particles; this would fit the previously reported lack of detection of molecular-level motifs necessary of the effects of pLL on DCs. Finally, we report that DCs exposed to pLL are able to condition DCs not exposed to the material so that these cannot upregulate CD40 in full in response to LPS.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Pittini, &Aacute;lvaro.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Yamila E. Mart&iacute;nez Acosta</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Casaravilla, Cecilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Seoane, Paula.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>R&uuml;ckerl, Dominik</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Quijano, Celia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Allen, Judith E.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiR-faO27_mAhUAGrkGHbG5AxwQFjAAegQIBBAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2Fpdf%2F%3Fc855a45b7dae1af50c961a96b5eb15c26a7b943e53f84d972caa0f9ce21ec5f03ef21e57ce461b5656b60c7a13dbc71dbc1dad52a109e231d5b638ac5639067d&amp;usg=AOvVaw2-p60bssNmxkcYsJPe3H-P" target="_self"><strong>D&iacute;az, Alvaro.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Infection and Immunity v. 87, no. 12, 2019. -- p. 1-19.--e00641-19]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Society for Microbiology]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1128/IAI.00641-19]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5992">
    <dcterms:title><![CDATA[<strong>First total synthesis of versicotide D and analogs</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[MALARIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[CICLOPEPTIDOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The first total synthesis of cyclotetrapeptide versicotide D has been achieved in 21% overall yield using solid phase peptide synthesis and solution cyclization. In addition, in the search for candidates of antimalarial new drugs, one cyclic tetrapeptide analog which differs in the sequence, and four cyclic pentapeptide containing N-methyl amino acids, were prepared. The obtained compounds were evaluated against P. falciparum 3D7. Versicotide D showed low micromolar antiplasmodial activity.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Posada, Laura</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiw6_XV6L_mAhVmFbkGHZYQCHoQFjAAegQIBRAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3Dce3355fb23e003850e4fa1f06c5342b918dfd64cda25912cab59933f806ac0b8e59fe24423e4d254d567d26b057887c43b50474a1c989777b54ad95d60ba9790%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw2ZhYNEIJkYiPf8IaLi9C6H" target="_self"><strong>Serra, Gloria</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Tetrahedron Letters v. 60, no. 48, 2019. --p. 1-4.--e151281]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1016/j.tetlet.2019.151281]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5993">
    <dcterms:title><![CDATA[<strong>Isolation and Characterization of Melanoidins from Dulce de Leche, A Confectionary Dairy Product</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ALIMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PRODUCTOS LACTEOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[DULCE DE LECHE]]></dcterms:subject>
    <dcterms:subject><![CDATA[LECHE]]></dcterms:subject>
    <dcterms:subject><![CDATA[MELANOIDINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[AISLAMIENTO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Melanoidins, the brown-colored compounds formed through the Maillard reaction, are responsible for color development in dulce de leche (DL), a popular confectionary dairy product in the R&iacute;o de la Plata region, particularly in Uruguay and Argentina. Color is a critical quality parameter that strongly influences consumer preference. This work aimed to develop a method to perform preliminary structural characterization of the chromophores produced by the Maillard reaction. Melanoidins are present in a water-insoluble fraction, linked to a protein backbone, conforming melanoproteins of high molecular weight. The insoluble melanoprotein fraction (10% total solids) was isolated, and the chromophores released by proteolysis and isolated by gel-permeation chromatography. The analysis of the products revealed that they present a high degree of molecular weight (MW) polydispersity, in a range of 300 to 2000 Da, where the compounds of higher molecular weight contributed the most to the color of the product. The isolated fractions were further analyzed by RP-HPLC using a diode array detector (DAD) detector. These results, together with H-NMR data, suggested that the chromophores isolated belonged to a relatively simple mixture of aromatic products with higher hydrophobic character relative to other products of the melanoprotein digestion.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez, Anal&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lema, Patricia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bessio, Mar&iacute;a In&eacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwistL-_47_mAhU6HrkGHSVCCNkQFjAAegQIAxAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D2cebe78e18fa760a7d79dd8a0021057dde02e9333677a6c5fcca4cd9f2ebc8ff20700be3044d46d4a23ffbe14bb8f73a516209099e443241db3b37bd796008fb%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw1qpXPqoOuSSI4F6X0VKVYQ" target="_self"><strong>Moyna, Guillermo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=d11c26cbdf6f83e1b698f2295eb1a656b438d8294df4c60bfab9dd74edd4e75c5b0cd885b9ba830f2cbcae24f01f723e424db116f691c751a4a3f7192c98827a&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Panizzolo, Luis Alberto</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong><a href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwiGk83Y3L_mAhVuIbkGHbYXCOwQFjAAegQIAxAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D83599915c2932d7ab87a1eb547042501ece38f26e6163f01a8a8aa642db67da505e5a1cb01f616571f4202b7d0c69a4823a7bdd022d839b2ff14f463b04195b3%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw1XjRVBgSdzxxVH1EdfAlFh">Ferreira, Fernando.</a></strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Molecules v. 24, no. 22, 2019. -- p. 1-14.--e4163]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.3390/molecules24224163]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5994">
    <dcterms:title><![CDATA[<strong>Anatomical and Biochemical Changes Induced by Gluconacetobacter diazotrophicus Stand Up for Arabidopsis thaliana Seedlings From Ralstonia solanacearum Infection</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANATOMIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIOQUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[GLUCONACETOBACTER DIAZOTROPHICUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[RALSTONIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Nowadays, fertilization and pest control are carried out using chemical compounds that contaminate soil and deteriorate human health. Plant growth promoting bacteria endophytes (PGPBEs), are a well-studied group of bacteria that offers benefits to the host plant, such as phytostimulation, biofertilization, and protection against other microorganisms. The study of Gluconacetobacter diazotrophicus&ndash;which belongs to PGPBEs-aids the development of alternative strategies of an integrated approach for crop management practices. Ralstonia solanacearum is responsible for bacterial wilt disease. This phytopathogen is of great interest worldwide due to the enormous economic losses it causes. In this study the action of G. diazotrophicus as a growth promoting bacterium in Arabidopsis thaliana seedlings is analyzed, evaluating the antagonistic mechanisms of this beneficial endophytic bacterium during biotic stress produced by R. solanacearum. Effective colonization of G. diazotrophicus was determined through bacterial counting assays, evaluation of anatomical and growth parameters, and pigments quantification. Biocontrol assays were carried out with Ralstonia pseudosolanacearum GMI1000 model strain and R. solanacearum A21 a recently isolated strain. Inoculation of A. thaliana (Col 0) with G. diazotrophicus Pal 5 triggers a set of biochemical and structural changes in roots, stems, and leaves of seedlings. Discrete callose deposits as papillae were observed at specific sites of root hairs, trichomes, and leaf tissue. Upon R. pseudosolanacearum GMI1000 infection, endophyte-treated plants demonstrated being induced for defense through an augmented callose deposition at root hairs and leaves compared with the non-endophyte-treated controls. The endophytic bacterium appears to be able to prime callose response. Roots and stems cross sections showed that integrity of all tissues was preserved in endophyte-treated plants infected with R. solanacearum A21. The mechanisms of resistance elicited by the plant after inoculation with the endophyte would be greater lignification and sclerosis in tissues and reinforcement of the cell wall through the deposition of callose. As a consequence of this priming in plant defense response, viable phytopathogenic bacteria counting were considerably fewer in endophyte-inoculated plants than in not-inoculated controls. Our results indicate that G. diazotrophicus colonizes A. thaliana plants performing a protective role against the phytopathogenic bacterium R. solanacearum promoting]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez, Mar&iacute;a V.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Tano, Josefina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ansaldi, Nazarena</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Carrau, Anal&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Srebot, Mar&iacute;a S.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ferreira, Virginia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mart&iacute;nez, Mar&iacute;a L.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cortadi, Adriana A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Siri, Mar&iacute;a In&eacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Orellano, Elena G.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Frontiers in Plant Science v. 10, 2019. -- p. 1-20.--e1618]]></dcterms:source>
    <dcterms:publisher><![CDATA[Frontiers Media]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.3389/fpls.2019.01618]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5995">
    <dcterms:title><![CDATA[<strong>Exploring oxidovanadium (IV) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[VANADIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[TRIPANOSOMA CRUZI]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTITRIPANOSOMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[LEISHMANIASIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Ten structurally related homoleptic complexes, including three new compounds, were synthesized: five [VIVO(L-H)2] and five [VVO(OCH3)(L-H)2] compounds, where L&ndash;H = L1-H&ndash;L5-H are monodeprotonated L1&ndash;L5 8-hydroxyquinoline derivatives. The compounds were characterized in the solid state and in solution. All complexes show inhibitory activity against Trypanosoma cruzi and Leishmania infantum, most within the 0.2&ndash;5 &mu;M range, T. cruzi being more sensitive to the compounds than L. infantum. The compounds show high selectivities towards the parasite, evaluated using VERO cells as a mammalian cell model, as well as higher activity against T. cruzi than the reference antitrypanosomal drug nifurtimox. The antitrypanosomal activity depends on the nature of the substituents on the 8-hydroxyquinoline moiety, [VIVO(L1-H)2] (L1 = 5,7-dichloroquinolin-8-ol), with IC50 = 0.21 &mu;M, being the most active and selective compound of the series against T. cruzi, and one of the most active against L. infantum (IC50 = 2.5 &mu;M). A trypanocide effect of [VIVO(L1-H)2] was observed when incubating parasites with 10&times; the IC50 value and a late apoptotic/necrotic cell death mechanism is suggested. A preferred association with the soluble protein fraction of cells is also observed (49.4% of total vanadium association). [VIVO(L1-H)2] is shown to affect not only the infection potentiality of cell-derived trypomastigotes but also the proliferation of intracellular amastigotes, the two parasite stages more relevant in the mammalian host after infection. By measuring circular dichroism spectra of solutions containing either human serum apo-transferrin (apo-HTF) or bovine serum albumin (BSA) upon adding the compounds, it is shown that both the free ligands and the VIV- and VV-complexes bind to these proteins. From data determined from fluorescence quenching measurements with BSA, the determined Stern&ndash;Volmer constants are typically slightly higher for the ligand precursors than for the corresponding [VIVO(L1-H)2] compounds, the calculated conditional binding constants at pH = 7.4 being ca. 105&ndash;106. The fluorescence competition measurements with DNA bound to ethidium bromide typically yield relatively small decreases in fluorescence, VIV- and VV-complexes with L1 showing higher quenching.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Scalese, Gonzalo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=5c1ca4d55a5933a1752b3fc23d7cad09c4e5df59004aa474d3d272c7b6b5d79efe1957de15b2f0c75050b8d88b94dc89f36f3a8703836670d171bb4291eb6134&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Machado, Ignacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Correia, Isabel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Costa Pessoa, Jo&atilde;o</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bilbao, Luc&iacute;a.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>P&eacute;rez-D&iacute;az, Leticia.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=6bb5dcce3e2559101357796ca4a2b2d4c9ba6b3a978a0bd4c5dab0107081b73e1ff46dcf49a7de2b571ff7980c4a01789f09f1d7eac1b879a8553641f940b9a5&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Gambino, Dinorah.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[New Journal of Chemistry&nbsp; v. 43, no. 45, 2019.--p. 17756-17773]]></dcterms:source>
    <dcterms:publisher><![CDATA[Royal Society of Chemistry]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1039/C9NJ02589H]]></dcterms:identifier>
</rdf:Description></rdf:RDF>
