<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/">
<rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6072">
    <dcterms:title><![CDATA[<strong>Synthesis and Structure Insights of Two Novel Broad-Spectrum Antibacterial Candidates Based on (E)-N&prime;-[(Heteroaryl)methylene]adamantane-1-carbohydrazides</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIINFECCIOSOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESTRUCTURA CRISTALINA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESPECTROSCOPIA INFRAROJO]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESPECTROS UV-VIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Two new N&prime;-heteroarylidene-1-carbohydrazide derivatives, namely; E-N&prime;-[(pyridine-3-yl)methylidene]adamantane-1-carbohydrazide (1) and E-N&prime;-[(5-nitrothiophen-2-yl)methylidene]adamantane-1-carbohydrazide (2), were produced via condensation of adamantane-1-carbohydrazide with the appropriate heterocyclic aldehyde. Both compounds were chemically and structurally characterized by 1H-NMR, 13C-NMR, infrared and UV-vis spectroscopies, and single crystal X-ray diffraction. The study was complemented with density functional theory calculations (DFT). The results show an asymmetrical charge distribution in both compounds, with the electron density accumulated around the nitrogen and oxygen atoms, leaving the positive charge surrounding the N-H and C-H bonds in the hydrazine group. Consequently, the molecules stack in an antiparallel fashion in the crystalline state, although the contribution of the polar contacts to the stability of the lattice is different for 1 (18%) and 2 (42%). This difference affects the density and symmetry of their crystal structures. Both molecules show intense UV-Vis light absorption in the range 200&ndash;350 nm (1) and 200&ndash;500 nm (2), brought about by &pi; &rarr; &pi;* electronic transitions. The electron density difference maps (EDDM) revealed that during light absorption, the electron density flows within the &pi;-delocalized system, among the pyridyl/thiophene ring, the nitro group, and the N&prime;-methyleneacetohydrazide moiety. Interestingly, compounds 1 and 2 constitute broad-spectrum antibacterial candidates, displaying potent antibacterial activity with minimal inhibitory concentration (MIC) values around 0.5&ndash;2.0 &mu;g/mL. They also show weak or moderate antifungal activity against the yeast-like pathogenic fungus Candida albicans]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Al-Wahaibi, Lamya H.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Alvarez, Natalia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Blacque, Olivier</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Veiga, Nicol&aacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Al-Mutairi, Aamal A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>El-Emam, Ali A.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Molecules v. 25, no, 8, 2020--p.1-17.--e1934]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[https://doi.org/10.3390/molecules25081934]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6073">
    <dcterms:title><![CDATA[<strong>Biofilm Eradication Using Biogenic Silver Nanoparticles</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[NANOTECNOLOGIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIINFECCIOSOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[NANOPARTICULAS BIOGENICAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[NANO PARTICULAS DE PLATA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIBIOFILM]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Microorganisms offer an alternative green and scalable technology for the synthesis of value added products. Fungi secrete high quantities of bioactive substances, which play dual-functional roles as both reducing and stabilizing agents in the synthesis of colloidal metal nanoparticles such as silver nanoparticles, which display potent antimicrobial properties that can be harnessed for a number of industrial applications. The aim of this work was the production of silver nanoparticles using the extracellular cell free extracts of Phanerochaete chrysosporium, and to evaluate their activity as antimicrobial and antibiofilm agents. The 45&ndash;nm diameter silver nanoparticles synthesized using this methodology possessed a high negative surface charge close to &minus;30 mV and showed colloidal stability from pH 3&ndash;9 and under conditions of high ionic strength ([NaCl] = 10&ndash;500 mM). A combination of environmental SEM, TEM, and confocal Raman microscopy was used to study the nanoparticle-E. coli interactions to gain a first insight into their antimicrobial mechanisms. Raman data demonstrate a significant decrease in the fatty acid content of E. coli cells, which suggests a loss of the cell membrane integrity after exposure to the PchNPs, which is also commensurate with ESEM and TEM images. Additionally, these biogenic PchNPs displayed biofilm disruption activity for the eradication of E. coli and C. albicans biofilms]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Estevez, Mar&iacute;a Bel&eacute;n</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rafaelli, Sof&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mitchell, Scott G.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Faccio, Ricardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Albor&eacute;s, Silvana</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Molecules. .v.25, 2020. -- p. 1-14.--e2023]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.3390/molecules25092023" target="_blank">https://doi.org/10.3390/molecules25092023</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6074">
    <dcterms:title><![CDATA[<strong>C&mdash;H Amination via Nitrene Transfer Catalyzed by Mononuclear Non-Heme Iron-Dependent Enzymes</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ENZIMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIOCATALISIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[HIERRO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Expanding the reaction scope of natural metalloenzymes can provide new opportunities for biocatalysis. Mononuclear non‐heme iron‐dependent enzymes represent a large class of biological catalysts involved in the biosynthesis of natural products and catabolism of xenobiotics, among other processes. Here, we report that several members of this enzyme family, including Rieske dioxygenases as well as &alpha;‐ketoglutarate‐dependent dioxygenases and halogenases, are able to catalyze the intramolecular C&minus;H amination of a sulfonyl azide substrate, thereby exhibiting a promiscuous nitrene transfer reactivity. One of these enzymes, naphthalene dioxygenase (NDO), was further engineered resulting in several active site variants that function as C&minus;H aminases. Furthermore, this enzyme could be applied to execute this non‐native transformation on a gram scale in a bioreactor, thus demonstrating its potential for synthetic applications. These studies highlight the functional versatility of non‐heme iron‐dependent enzymes and pave the way to their further investigation and development as promising biocatalysts for non‐native metal‐catalyzed transformations.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Vila, Mar&iacute;a Agustina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Steck, Viktoria</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez Giordano, Sonia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Carrera, Ignacio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fasan, Rudi</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[ChemBioChem 2020. --p. 1-9]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos) <strong>La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong> literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[Pdf]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1002/cbic.201900783]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6075">
    <dcterms:title><![CDATA[<strong>Yeasts and Bacterial Consortia from Kefir Grains Are Effective Biocontrol Agents of Postharvest Diseases</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[LEVADURAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BACTERIAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[KEFIR]]></dcterms:subject>
    <dcterms:subject><![CDATA[PATOGENOS FUNGICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[FRUTAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Fungal pathogens in fruits and vegetables cause significant losses during handling, transportation, and storage. Biological control with microbial antagonists replacing the use of chemical fungicides is a major approach in postharvest disease control, and several products based on single antagonists have been developed but have limitations related to reduced and inconsistent performance under commercial conditions. One possible approach to enhance the biocontrol efficacy is to broaden the spectrum of the antagonistic action by employing compatible microbial consortia. Here, we explore commercial kefir grains, a natural probiotic microbial consortium, by culture-dependent and metagenomic approaches and observed a rich diversity of co-existing yeasts and bacterial population. We report effective inhibition of the postharvest pathogen Penicillium expansum on apple by using the grains in its fresh commercial and milk-activated forms. We observed few candidate bacteria and yeasts from the kefir grains that grew together over successive enrichment cycles, and these mixed fermentation cultures showed enhanced biocontrol activities as compared to the fresh commercial or milk-activated grains. We also report several individual species of bacteria and yeasts with biocontrol activities against Penicillium rots on apple and grapefruit. These species with antagonistic properties could be further exploited to develop a synthetic consortium to achieve enhanced antagonistic effects against a wide range of postharvest pathogens.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Yeka Zhimo, V.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Biasi, Antonio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Kumar, Ajay</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Feygenberg, Oleg</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Salim, Shoshana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Vero, Silvana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wisniewski, Michael</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Droby, Samir</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Microorganism v. 8, 2020. -- p. 1-16.--e428]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos) <strong>La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong> literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[Pdf]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.3390/microorganisms8030428]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6076">
    <dcterms:title><![CDATA[<p><strong>Caracterizaci&oacute;n arqueom&eacute;trica de cuentas y cer&aacute;micas prehisp&aacute;nicas de Huanchaco mediante t&eacute;cnicas y m&eacute;todos f&iacute;sicos </strong></p>
<p><strong>Archeometric characterization of pre-Hispanic beads and ceramics from Huanchaco by physical techniques and methods</strong></p>]]></dcterms:title>
    <dcterms:subject><![CDATA[CERAMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ARCILLAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[MATERIALES ARQUEOLOGICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[DIFRACCION DE RAYOS X]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The present study is concerned with the characterization of archaeological materials of beads and ceramics, from the archaeological sites "Iglesia Colonial" and "Pampa La Cruz" of Huanchaco, respectively. The beads of "Iglesia Colonial" were recorded in funerary contexts of the Chimu Inca Period (1450-1532 A.D.) and Early Colonial Period (1532-1650 A.D.). The importance of studying this site lies in understanding the evolution of human occupation between the Inca transition and the arrival of the Spaniards to the north coast of Peru. In the &ldquo;Pampa La Cruz&rdquo; site, tombs containing beads and ceramic vessels prepared with the decorative technique of &ldquo;the negative" were discovered. In this work fragments of the ceramics of this site were investigated, its mineralogical composition was determined qualitatively and quantitatively. This information would help to identify the possible source of clays used for the preparation of the vessels, which, in turn, could help determine if the vessels came from various places, or if the site's inhabitants themselves processed them.]]></dcterms:abstract>
    <dcterms:abstract><![CDATA[El presente estudio est&aacute; referido a la caracterizaci&oacute;n de materiales arqueol&oacute;gicos de cuentas y cer&aacute;micas, provenientes de los sitios arqueol&oacute;gicos &ldquo;Iglesia Colonial&rdquo; y &ldquo;Pampa La Cruz&rdquo; de Huanchaco, respectivamente. Las cuentas de &ldquo;Iglesia Colonial&rdquo; fueron registradas en contextos funerarios del Per&iacute;odo Chimu Inca (1450-1532 d.C.) y Colonial Temprano (1532-1650 d.C.). La importancia de estudiar este sitio radica en entender c&oacute;mo se dio la ocupaci&oacute;n humana entre la transici&oacute;n Inca y la llegada de los Espa&ntilde;oles a la costa norte del Per&uacute;. En el sitio &ldquo;Pampa La Cruz&rdquo; fueron descubiertas tumbas conteniendo cuentas y vasijas de cer&aacute;mica con la t&eacute;cnica decorativa del &ldquo;negativo&rdquo;. En este trabajo fragmentos de cer&aacute;mica de este sitio fueron investigados, su composici&oacute;n mineral&oacute;gica fue determinada cualitativa y cuantitativamente. Esta informaci&oacute;n contribuir&iacute;a a identificar la posible fuente de arcillas utilizadas para la preparaci&oacute;n de las vasijas, lo que, a su vez, podr&iacute;a ayudar a determinar si es que las vasijas proven&iacute;an de varios lugares, o si los mismos pobladores del sitio las procesaban.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Zeballos Vel&aacute;squez, Elvira</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Prieto, Gabriel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Suescun, Leopoldo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Asto, Esteban</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Moya, Frank</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Revista Mat&eacute;ria. v.25, no 1, 2020. --p. 1-10]]></dcterms:source>
    <dcterms:publisher><![CDATA[Rede Latino-Americana de Materiais]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:language><![CDATA[Espa&ntilde;ol]]></dcterms:language>
    <dcterms:type><![CDATA[Artículo]]></dcterms:type>
    <dcterms:identifier><![CDATA[On-line&nbsp;version&nbsp;ISSN 1517-7076]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6077">
    <dcterms:title><![CDATA[<strong>Multi-target heteroleptic palladium bisphosphonate complexes</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PALADIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[SINTESIS QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[TOXOPLASMOSIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ENFERMEDAD DE CHAGAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIPARASITARIOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIFOSFONATO DE PALADIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis and other bone illnesses. Some of them have also shown antiparasitic activity. In search of improving the pharmacological profile of commercial bisphosphonates, our group had previously developed first row transition metal complexes with N-containing bisphosphonates (NBPs). In this work, we extended our studies to heteroleptic palladium&ndash;NBP complexes including DNA intercalating polypyridyl co-ligands (NN) with the aim of obtaining potential multi-target species. Complexes of the formula [Pd(NBP)2(NN)]&middot;2NaCl&middot;xH2O with NBP&thinsp;=&thinsp;alendronate (ale) or pamidronate (pam) and NN&thinsp;=&thinsp;1,10 phenanthroline (phen) or 2,2&prime;-bipyridine (bpy) were synthesized and fully characterized. All the obtained compounds were much more active in vitro against T. cruzi (amastigote form) than the corresponding NBP ligands. In addition, complexes were nontoxic to mammalian cells up to 50&ndash;100 &micro;M. Compounds with phen as ligand were 15 times more active than their bpy analogous. Related to the potential mechanism of action, all complexes were potent inhibitors of two parasitic enzymes of the isoprenoid biosynthetic pathway. No correlation between the anti-T. cruzi activity and the enzymatic inhibition results was observed. On the contrary, the high antiparasitic activity of phen-containing complexes could be related to their ability to interact with DNA in an intercalative-like mode. These rationally designed compounds are good candidates for further studies and good leaders for future drug developments.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Cipriani, Micaella</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rost&aacute;n, Santiago</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Le&oacute;n, Ignacio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Li, Zhu‑Hong</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gancheff, Jorge S.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Kemmerling , Ulrike</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Olea Azar, Claudio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Etcheverry, Susana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Docampo, Roberto</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gambino, Dinorah</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Otero, Luc&iacute;a</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Biological Inorganic Chemistry. v.25, no. 3, 2020. -- p. 509-519]]></dcterms:source>
    <dcterms:publisher><![CDATA[Springer]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.1007/s00775-020-01779-y" target="_blank">https://doi.org/10.1007/s00775-020-01779-y</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6078">
    <dcterms:title><![CDATA[<strong>A nanobody-based test for highly sensitive detection of hemoglobin in fecal samples</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[HEMOGLOBINA]]></dcterms:subject>
    <dcterms:subject><![CDATA[MUESTRAS FECALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[INMUNOENSAYO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Colon cancer has a high prevalence worldwide and is a serious public health problem. Early diagnosis greatly improves its prognosis and, among the existing methods, the detection of fecal occult blood is the only noninvasive test recommended for screening of the disease. To promote its massive application as a screening tool for asymptomatic populations in low-resource settings, the availability of a reliable and cost-effective method is imperative. Here, we describe the development and validation of a sensitive nanobody-based immunoassay for the detection of hemoglobin in human fecal samples. The nanobodies were selected from a library generated from a llama immunized with human hemoglobin, using a high-throughput platform that enabled the identification of the best nanobody pair. The assay allowed a sub-ng/mL limit of detection to be reached in phosphate-buffered saline, and was validated with stool samples, showing excellent reproducibility (CV% &lt; 15 inter-day precision) and accuracy at 2 and 4 &mu;g of hemoglobin per gram of feces, which are well below the recommended cutoff for this test (10&ndash;20 &mu;g/g). Moreover, no cross-reactivity was observed with a panel of dietary non-human hemoglobins removing the need for pre-test dietary restrictions. Considering that the monodomain nature of nanobodies facilitates their straightforward and low-cost production by bacterial fermentation, with their provided sequences and using synthetic genes, the assay reported here could be replicated in any laboratory to perform thousands of tests for early detection of colorectal cancer at almost no cost.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Delfin-Riela, Triana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rossoti, Mart&iacute;n A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Echaides, C&eacute;sar</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gonz&aacute;lez Sapienza, Gualberto</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Analytical and Bioanalytical Chemistry . v. 412, 2020. -- p. 389-396]]></dcterms:source>
    <dcterms:publisher><![CDATA[Springer]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.1007/s00216-019-02246-7" target="_blank">https://doi.org/10.1007/s00216-019-02246-7</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6079">
    <dcterms:title><![CDATA[<strong>Characterization and stability analysis of anthocyanins from Pachyrhizus ahipa (Wedd) Parodi roots</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[LEGUMINOSAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPOSICION QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPUESTOS FENOLICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTOCIANINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PACHYRHIZUS AHIPA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Pachyrhizus ahipa is an Andean leguminous plant which has purple-pigmented edible roots. The content and distribution of the phenolic compounds in the skins and flesh of P. ahipa roots as well as their antioxidant capacity were studied. Total phenols, flavonoids, tannins and anthocyanins were quantified and the effect of the extraction solvent on the maximum absorbance wavelength (&lambda;vis-max) was measured. The ATR-FTIR spectrum and stability of the purified anthocyanin extracts were analyzed. Individual anthocyanins were partially characterized using high-performance liquid chromatography-mass spectrometry and absorbance spectra. Ahipa skins had much more phenols (3.25 mg gallic acid equivalents/g), flavonoids (3.0 mg catechin equivalents/g) and tannins (4.6 mg tannic acid equivalents/g) than the flesh, which was reflected in a higher antioxidant capacity. Changing the extraction solvent from acidified methanol to acidified water shifted the &lambda;vis-max 16 nm lower, suggesting copigmentation reactions. Anthocyanin in the skins was &gt;8.7 content in the flesh, and the chromatographic analysis showed at least 6 different anthocyanins with identical retention times for skins and flesh, including delphinidin, pelargonidin and cyanidin as aglycons. The absorbance spectra showed that two of them are acylated structures. Pigments were stable for at least 180 min at pH 1 and 25 &deg;C, but they were affected by increased pH and temperature. These anthocyanins may be a potential source of natural pigments.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Dini, C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Zaro, M. J.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rolny, N.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Caputo, M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Boido, Eduardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dellacassa, Eduardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Vi&ntilde;a, S. Z.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Food Bioscience. v, 34, 2020. -- p. 1-7.--e100534]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.1016/j.fbio.2020.100534" target="_blank">https://doi.org/10.1016/j.fbio.2020.100534</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6080">
    <dcterms:title><![CDATA[<strong>Valorisation of Schinus molle fruit as a source of volatile compounds in foods as flavours and fragrances</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[BAYAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPUESTOS VOLATILES]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPUESTOS GLICOSILADOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[SCHINUS MOLLE]]></dcterms:subject>
    <dcterms:subject><![CDATA[AROMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Giuffrida, Daniele</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mart&iacute;nez, Natalia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Arrieta-Garay, Yanine</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fari&ntilde;a, Laura</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Boido, Eduardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dellacassa, Eduardo</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Food Research International v. 133, 2020. -- p. 1-7. --e109103]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[https://doi.org/10.1016/j.foodres.2020.109103]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6081">
    <dcterms:title><![CDATA[<strong>Interfacial and emulsifying properties of whey protein concentrate by ultrafiltration</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PROTEINAS
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[PROTEINAS DE SUERO
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[EMULSIONANTES
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[ULTRAFILTRACION
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The aim of this study was to concentrate whey protein by ultrafiltration process, evaluating the pressure at 1&ndash;3&thinsp;bar and temperature of 10&ndash;20℃. In the conditions that show the more protein concentration were evaluated the interfacial and emulsifying properties at pH 5.7 and 7.0. The whey concentrate at 10℃ and 1.5&thinsp;bar showed the higher protein value 36% (w/w), with soluble protein of 33.82% (solubility of 93.94%) for pH 5.7 and 34% (solubility of 94.4%) for pH 7.0, respectively. The whey concentrate powder present particle size distribution between 0.4-110 um. The whey at pH 5.7 and 7.0 was not observed significant differences in the resistance parameters of the oil/water layer interface. The interfacial film formed by the proteins presented an essentially elastic behavior in both pH, and in pH 5.7 the emulsion was more stable with lower diameter droplets. The concentrate whey showed techno-functional properties (emulsification and solubility), which allow the use as ingredients in products of industrial interest in food products such as mayonnaise, ice cream, sauces, and others.
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Kilian, Josiane</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fernandes, Ilizandra Aparecida</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lupatini Menegotto, Anne Luize</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Steffens, Clarice</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Abirached, Cecilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Steffens, Juliana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Valduga, Eunice</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Food Science and Technology International v. 26, no. 8, 2020. -- p.657-665<br />
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:source>
    <dcterms:publisher><![CDATA[Sage
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.1177/1082013220921595" target="_blank">https://doi.org/10.1177/1082013220921595</a>
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6082">
    <dcterms:title><![CDATA[<strong>Optimization and validation of a single method for the determination of pesticide residues in Peumus boldus Molina leaves using GC-MSD, GC-MS/MS and LC-MS/MS</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:subject><![CDATA[PLANTAS MEDICINALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[PESTICIDAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANALISIS DE RESIDUOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PESTICIDAS-RESIDUOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[CROMATOGRAFIA DE GASES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESPECTROMETRIA DE MASAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PEUMUS BOLDUS]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The QuEChERS methods, CEN 15662 and AOAC 2007.01, and different clean-up variations were applied to the determination of pesticide residues in Peumus boldus Molina leaves, using LC and GC coupled to single and tandem mass spectrometry. Boldo belongs to the class of medicinal and aromatic plants. Because of its complex chemical composition including terpene peroxides, alkaloids and phenolic acids at concentrations typically 100-fold higher than that of a possible contaminant, it is a very challenging matrix for pesticide residue determination. Thin layer chromatography was used to evaluate the efficacy of removal of matrix co-extractives using different clean-up sorbents, including neutral alumina, graphitized carbon black (GCB), octadecyl reverse phase silica gel (RP-C18) and pH modification in the extraction and clean-up steps. The most promising method was a combination of GCB, RP-C18 and primary-secondary amine (PSA) within the QuEChERS template. The final optimized method was validated according to the SANTE guidelines using LC&ndash;MS/MS and GC&ndash;MS/MS. The method scope includes 84 representative pesticide residues with recoveries ranging from 70 to 119% and within laboratory relative standard deviations below 15%. The method was initially validated for 25 representative pesticides using GC-MSD, making it applicable in those laboratories equipped only with a single mass detector. It is important to emphasize that the method complies with the requirements of international pharmacopoeias and food regulatory agencies, since herbal teas are found in both categories, as herbal remedies and foods.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Maestroni, Britt</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Besil, Natalia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bojorge, Alejandra</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>G&eacute;rez, Natalia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>P&eacute;rez Parada, Andr&eacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cannavan, Andrew</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Heinzen, Horacio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cesio, Mar&iacute;a V.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Applied Research on Medicinal and Aromatic Plants 2020.--p. 1-9.--e100154]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong> literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1016/j.jarmap.2020.100254]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6083">
    <dcterms:title><![CDATA[<strong>High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTITRIPANOSOMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[VANADIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[ENFERMEDAD DE CHAGAS]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Treatment for Chagas disease, a parasitosis caused by Trypanosoma cruzi, has always been based on two drugs, nifurtimox and benznidazole, despite the toxic side effects described after prolonged prescription. In this work, we study a new prospective antitrypanosomal drug based on vanadium, here named VIVO(5Brsal)(aminophen). We found a good IC50 value, (3.76 &plusmn; 0.08) &mu;M, on CL Brener epimastigotes. The analysis of cell death mechanism allowed us to rule out the implication of a mechanism based on early apoptosis or necrosis. Recovery assays revealed a trypanostatic effect, accompanied by cell shape and motility alterations. An uptake mostly associated with the insoluble fraction of the parasites was deduced through vanadium determinations. Concordantly, no drastic changes of the parasite transcriptome were detected after 6 h of treatment. Instead, proteomic analysis uncovered the modulation of proteins involved in different processes such as energy and redox metabolism, transport systems, detoxifying pathways, ribosomal protein synthesis, and proteasome protein degradation. Overall, the results here presented lead us to propose that VIVO(5Brsal)(aminophen) exerts a trypanostatic effect on T. cruzi affecting parasite insoluble proteins.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Mosquillo, M. Florencia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Smircich, Pablo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lima, Anal&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gehrke, Sergio A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Scalese, Gonzalo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Machado, Ignacio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gambino, Dinorah</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Garat, Beatriz</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>P&eacute;rez-D&iacute;az, Leticia</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Bioinorganic Chemistry and Applications 2020. -- p.1-10.--e1634270]]></dcterms:source>
    <dcterms:publisher><![CDATA[Hindawi]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos) <strong>La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong> literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1155/2020/1634270]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6084">
    <dcterms:title><![CDATA[<strong>HIF-1 Has a Central Role in Caenorhabditis elegans Organismal Response to Selenium</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[SELENIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[SELENITO]]></dcterms:subject>
    <dcterms:subject><![CDATA[SULFURO]]></dcterms:subject>
    <dcterms:subject><![CDATA[CAENORHABDITIS ELEGANS ORGANISMAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Selenium is a trace element for most organisms; its deficiency and excess are detrimental. Selenium beneficial effects are mainly due to the role of the 21st genetically encoded amino acid selenocysteine (Sec). Selenium also exerts Sec-independent beneficial effects. Its harmful effects are thought to be mainly due to non-specific incorporation in protein synthesis. Yet the selenium response in animals is poorly understood. In Caenorhabditis elegans, Sec is genetically incorporated into a single selenoprotein. Similar to mammals, a 20-fold excess of the optimal selenium requirement is harmful. Sodium selenite (Na2SeO3) excess causes development retardation, impaired growth, and neurodegeneration of motor neurons. To study the organismal response to selenium we performed a genetic screen for C. elegans mutants that are resistant to selenite. We isolated non-sense and missense egl-9/EGLN mutants that confer robust resistance to selenium. In contrast, hif-1/HIF null mutant was highly sensitive to selenium, establishing a role for this transcription factor in the selenium response. We showed that EGL-9 regulates HIF-1 activity through VHL-1, and identified CYSL-1 as a key sensor that transduces the selenium signal. Finally, we showed that the key enzymes involved in sulfide and sulfite stress (sulfide quinone oxidoreductase and sulfite oxidase) are not required for selenium resistance. In contrast, knockout strains in the persulfide dioxygenase ETHE-1 and the sulfurtransferase MPST-7 affect the organismal response to selenium. In sum, our results identified a transcriptional pathway as well as enzymes possibly involved in the organismal selenium response.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Romanelli-Credrez, Laura</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Doitsidou, Mar&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Alkema, Mark J.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Salinas, Gustavo</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Frontiers in Genetics v. 11, 2020. -- p. 1-11.--e63]]></dcterms:source>
    <dcterms:publisher><![CDATA[Frontiers]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong> literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.3389/fgene.2020.00063]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6085">
    <dcterms:title><![CDATA[<strong>Unraveling the role of additional OH-radicals in the H&ndash;Abstraction from Dimethyl sulfide using quantum chemical computations</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[QUIMICA ATMOSFERICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[SULFURO DE DIMETILO]]></dcterms:subject>
    <dcterms:subject><![CDATA[OXIDACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Dimethyl sulfide (DMS) is the main organosulfur compound in the atmosphere. Oxidation by OH radicals to form the methyl thiomethyl species (MTMr) has been studied under normal atmospheric conditions and in reaction chambers at different O2 partial pressure, including complete absence of oxygen. Scarce attention has been devoted however to the possibility of further reaction of OH with MTMr. We present here a computational study using DFT, CCSD(T) and composite methods, on the properties of two stable intermediates never fully investigated before, methanesulfenyl methanol (MSMOH) and S-methyl-methanesulfenic acid (SMMSA), arising from addition of a second OH radical to MTMr.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Zalta, Soi</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lupi, Jocobo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Tasinato, Nicola</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Varone, Vincenzo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ventura, Oscar N.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chemical Physics Letters v. 739, 2020. --p. 1-9.--E136963]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos) <strong>La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;</strong>n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1016/j.cplett.2019.136963]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6086">
    <dcterms:title><![CDATA[<strong>Immune profiling of breast milk from mothers with treated celiac disease</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ENFERMEDAD CELIACA]]></dcterms:subject>
    <dcterms:subject><![CDATA[LECHE MATERNA]]></dcterms:subject>
    <dcterms:subject><![CDATA[PERFIL INMUNE]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Background The protective effect of breastfeeding on celiac disease (CD) onset is controversial. We studied a wide range of milk components in milk produced by celiac mothers following long-term gluten-free diet (GFD) in comparison to milk produced by healthy mothers. Methods Breast-milk samples from celiac (n&thinsp;=&thinsp;33) and healthy (n&thinsp;=&thinsp;41) mothers were obtained during the first year of lactation. A panel of bioactive components was analyzed by enzyme-linked immunosorbent assay in the aqueous fraction. We studied molecules involved in defenses, immunoregulation, and strengthening of the gut&ndash;epithelial barrier. Results During late lactation (from 6 to 12 months after delivery), the content of total immunoglobulin A (IgA) and IgM was significantly lower in the milk produced by celiac patients. Nevertheless, gliadin (GFD)-specific IgA relative contribution was higher in this group, in contrast to tetanus toxoid-specific antibodies. The balance between pro-inflammatory and anti-inflammatory molecules was different. While interleukin-6, tumor necrosis factor-&alpha;, and monocyte chemoattractant protein-1 were most frequently found in samples from celiac mothers, soluble Toll-like receptor-2 prevalence was lower. Conclusions We describe differences between the innate and adaptive immune profile of milk produced by celiac and healthy mothers. These results might explain previous controversial reports about breastfeeding and CD protection.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Villamil, Emilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez-Camejo, Claudio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Puyol, Arturo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fazio, Laura</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Colistro, Valentina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Hern&aacute;ndez, Ana</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Pediatric Research 2020.-- p. 1-9]]></dcterms:source>
    <dcterms:publisher><![CDATA[Springer]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Auto</strong>r (Por favor lea este aviso antes de abrir los documentos u objetos) <strong>La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;</strong>n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1038/s41390-020-0901-y]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6087">
    <dcterms:title><![CDATA[<strong>Comparative high-throughput analysis of the Trypanosoma cruzi response to organometallic compounds</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ENFERMEDAD DE CHAGAS
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[TRIPANOSOMA CRUZI
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPUESTOS ORGANOMETALICOS
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:abstract><![CDATA[There is an urgent need to develop new drugs against Chagas&rsquo; disease. In addition, the mechanisms of action of existing drugs have not been completely worked out at the molecular level. High throughput approaches have been demonstrated to be powerful tools not only for understanding the basic biology of Trypanosoma cruzi, but also for the identification of drug targets such as proteins or pathways that are essential for parasite infection and survival within the mammalian host. Here, we have applied these tools towards the discovery of the effects of two organometallic compounds with trypanocidal activity, Pd&ndash;dppf&ndash;mpo and Pt&ndash;dppf&ndash;mpo, on the transcriptome and proteome of T. cruzi epimastigotes. These approaches have not yet been reported for any other prospective metal-based anti T. cruzi drug. We found differentially expressed transcripts and proteins in treated parasites. Pd&ndash;dppf&ndash;mpo treatment resulted in more modulated transcripts (2327 of 10 785 identified transcripts) than Pt&ndash;dppf&ndash;mpo treatment (201 of 10 773 identified transcripts) suggesting a mechanism of action for Pd&ndash;dppf&ndash;mpo at the transcriptome level. Similar numbers of differentially expressed proteins (342 and 411 for Pd&ndash;dppf&ndash;mpo and Pt&ndash;dppf&ndash;mpo respectively) were also observed. We further functionally categorized differentially expressed transcripts and identified cellular processes and pathways significantly impacted by treatment with the compounds. Transcripts involved in DNA binding, protein metabolism, transmembrane transport, oxidative defense, and the ergosterol pathways were found to be modulated by the presence of the compounds. Our transcriptomic dataset also contained previously validated essential genes. These data allowed us to hypothesize a multimodal mechanism of action for the trypanocidal activity of Pd&ndash;dppf&ndash;mpo and Pt&ndash;dppf&ndash;mpo, and a differential contribution of the metal moiety of each compound.
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Mosquillo, M. Florencia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Smircich, Pablo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ciganda, Mart&iacute;n</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lima, Anal&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gambino, Dinorah</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Garat, Beatriz</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>P&eacute;rez-D&iacute;az Beatriz</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Metallomics&nbsp; v. 12, no. 5, 2020. -- p.813-828<br />
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:source>
    <dcterms:publisher><![CDATA[Royal Society of Chemistry
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong>literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1039/D0MT00030B
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6088">
    <dcterms:title><![CDATA[<strong>Bismuth chalcohalide-based nanocomposite for application in ionising radiation detectors</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[SEMICONDUCTORES]]></dcterms:subject>
    <dcterms:subject><![CDATA[NANOCOMPUESTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[RADIACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[CALCOHALURO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Bismuth sulpho iodide (BiSI) belongs to the family of chalcohalides, which present several attractive electro-optic properties. In particular, BiSI is a semiconductor which could be used in X and gamma ray detection due to a band gap of 1.6 eV, density of 6.4 g cm&minus;3, and absorption coefficient for 60 keV radiation of 5.6 cm2 g&minus;1. This work presents a facile synthesis under solvothermal conditions of a nanocomposite consisting of BiSI nanorods and amorphous carbon structures. Furthermore, it studies its ionising radiation detection properties at room temperature, when prototype detectors were built from pellets. The construction conditions of pellets were also studied, varying the applied pressure and heat treatment to the nanocomposite. Dark current density and response to different exposure rates of a 241Am source were measured for the prototype detectors built. It was found that heat treatment of pellets considerably improves detectors performance. Dark current density was one order of magnitude lower than for the pellets without heat treatment, and its response to the 241Am source, linear, with a signal to noise ratio of 7 for 20 V. Finally, the resistivity for the heat treated detector was in the order of 1011 &Omega; cm, comparable to other materials studied for this application.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Mombr&uacute; Frutos, Maia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>P&eacute;rez Barthaburu, Mar&iacute;a Eugenia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fornaro, Laura</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;ved=2ahUKEwiurpTj1b_mAhXoIbkGHb4qC2cQFjAAegQIBBAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3Deb05af54e8688a7393c7457148063acf342670300c9d3be26f9a361391b035515e0faa9348d01d2f06508c0b2e370a250fc1d36e812ed8612f610da0d3984df6%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw3Znd45wDSCkgnl37ERjqEU" target="_blank"><strong>Aguiar, Ivana</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Nanotechnology v.31, 2020. -- p.1-10.--E225710]]></dcterms:source>
    <dcterms:publisher><![CDATA[IOP Science]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos) <strong>La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong> literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1088/issn.0957-4484]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6089">
    <dcterms:title><![CDATA[<strong>A Single Administration of the Atypical Psychedelic Ibogaine or its Metabolite Noribogaine Induces an Antidepressant-like Effect in Rats</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIDEPRESIVOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[DROGAS PSICODELICAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[SEROTONINA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Anecdotal reports and open-label case studies in humans indicated that the psychedelic alkaloid ibogaine exerts profound antiaddictive effects. Ample preclinical evidence demonstrated the efficacy of ibogaine, and its main metabolite, noribogaine, in substance-use-disorder rodent models. In contrast to addiction research, depression-relevant effects of ibogaine or noribogaine in rodents have not been previously examined. We have recently reported that the acute ibogaine administration induced a long-term increase of brain-derived neurotrophic factor mRNA levels in the rat prefrontal cortex, which led us to hypothesize that ibogaine may elicit antidepressant-like effects in rats. Accordingly, we characterized behavioral effects (dose- and time-dependence) induced by the acute ibogaine and noribogaine administration in rats using the forced swim test (FST, 20 and 40 mg/kg i.p., single injection for each dose). We also examined the correlation between plasma and brain concentrations of ibogaine and noribogaine and the elicited behavioral response. We found that ibogaine and noribogaine induced a dose- and time-dependent antidepressant-like effect without significant changes of animal locomotor activity. Noribogaine's FST effect was short-lived (30 min) and correlated with high brain concentrations (estimated &gt;8 &mu;M of free drug), while the ibogaine's antidepressant-like effect was significant at 3 h. At this time point, both ibogaine and noribogaine were present in rat brain at concentrations that cannot produce the same behavioral outcome on their own (ibogaine &sim;0.5 &mu;M, noribogaine &sim;2.5 &mu;M). Our data suggests a polypharmacological mechanism underpinning the antidepressant-like effects of ibogaine and noribogaine.
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez, Paola</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Urbanavicius, Jessika</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Prieto, Jos&eacute; Pedro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fabius, Sara</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Habel, Vaclav</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Sames, Dalibor</strong>&gt;]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Scorza, Cecilia</strong>&gt;]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Carrera, Ignacio</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[ACS Chemical Neuroscience v. 11, no. 11, 2020.-- p. 1661-1672]]></dcterms:source>
    <dcterms:publisher><![CDATA[ACS]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos) <strong>La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong>literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1021/acschemneuro.0c00152
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6090">
    <dcterms:title><![CDATA[<strong>Biogenic silver nanoparticles: understanding the antimicrobial mechanism using Confocal Raman Microscopy</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[NANOPARTICULAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIINFECCIOSOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[MICROSCOPIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[PLATA BIOGENICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The antimicrobial properties of silver nanoparticles (AgNPs) have made them ubiquitous in a number of real-world industrial applications; however, the antimicrobial mode of action of biogenic AgNPs is not entirely understood. The use of Raman spectroscopy can provide molecular fingerprint information on various chemical and biochemical components in complex systems like microbial cultures, without the need for any complex sample pre-treatment. Consequently, the antimicrobial mechanism of AgNPs can be inferred through morphological and compositional changes of microbial cells that are monitored via changes in Raman band profiles. Here we show the synthesis of biogenic AgNPs using the extracellular cell-free filtrates of Penicillium expansum. The antimicrobial activity of the Penicillium expansum synthesized silver nanoparticles (hereafter PeNPs) was evaluated and the interactions between the nanoparticles and Escherichia coli were studied using Transmission Electron Microscopy (TEM) and Environmental Scanning Electron Microscopy (ESEM), showing the attachment of PeNPs to the surface of the bacteria and rupture of the bacterial cell membrane. Importantly, we show how Confocal Raman Microscopy can be used as an innovative approach to study the antimicrobial mechanisms, the results of which confirm that the PeNPs induce damage to bacterial and fungal cells, resulting in critical changes to polysaccharides, lipids, proteins and nucleic acids.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Estevez, Mar&iacute;a Bel&eacute;n</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mitchell, Scott G.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Faccio, Ricardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Albor&eacute;s, Silvana</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Materials Research Express V.6, NO.12, 2020. -- p.1-11]]></dcterms:source>
    <dcterms:publisher><![CDATA[IOP Science]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n</strong> literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1088/2053-1591/ab6636]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6091">
    <dcterms:title><![CDATA[<strong>Structural analysis of oxyfluoride borate glass and BaF2 crystallization from phase separation</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[BORATO]]></dcterms:subject>
    <dcterms:subject><![CDATA[VIDRIO DE BORATO]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANALISIS ESTRUCTURAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Oxyfluoride glass and glass‐ceramics are being studied due to the possibility of their utilization in many applications, such as thermoluminescent dosimeters, optical fibers, fluorescent concentrators, and temperature sensors. In order to improve the properties of glass, they are often crystallized. For this crystallization to be effective, knowledge and control of the structure of the starting material is required. Much work was done on silicate glass; however, a great interest exists in obtaining these kinds of materials in other matrices such as germanates, phosphates, and borates. Here, we present a structural study of some oxyfluoride borate glass with different concentrations of PbF2 by means of Nuclear Magnetic Resonance (NMR), Raman, and Fourier Transform Infrared (FTIR) spectroscopies. We also analyzed glass‐crystallization using Differential Scanning Calorimetry (DSC). The crystallization study was complemented with the use of Transmission Electron Microscopy (TEM) and Selected Area Electron Diffraction (SAED), for the purpose of identifying possible mechanisms of crystallization. Our results indicate, from the structural point of view, that the glass present groups with one or two BO4 species, such as diborate or pentaborate. The small variation in the BO4 fraction with the increase in PbF2 concentration would be an indication of the formation of F&minus;BO3/2 species. Oxyfluoride borate glass containing BaO as a cation modifier and 30% PbF2 represents a good starting point for obtaining glass‐ceramics with a narrow size distribution of BaF2 nanocrystals. We also propose that the possible mechanism for oxyfluoride borate glass crystallization started with a separation of phases.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez Chialanza, Mauricio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Scheneider, Jos&eacute; Fabian</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Keuchkerian, Romina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Romero, Mariano</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Faccio, Ricardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Olivera, Alvaro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bentos Pereira, Heinkel</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of the American Ceramic Society v. 103, no. 5, 2020. --p.3126-3137]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Ceramic Society]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos) La legislaci&oacute;n uruguaya protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[https://doi.org/10.1111/jace.17022]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6092">
    <dcterms:title><![CDATA[<strong>Sick, salient and full of salt, sugar and fat: Understanding the impact of nutritional warnings on consumers&rsquo; associations through the salience bias</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ALIMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[INFORMACION NUTRICIONAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[POLITICA PUBLICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[SAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[GRASAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPORTAMIENTO DE CONSUMIDORES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The aim of the present work was to explore the effect of the inclusion of nutritional warnings on consumer associations with labels of ultra-processed products. The study was conducted in Uruguay at two points in time, before and after the compulsory implementation of nutritional warnings. A total of 163 participants evaluated three labels of ultra-processed products using a word association task. In the first evaluation (T1), performed 9 months before the entry into force of nutritional warnings, labels were presented without warnings. Nine months later (15 days after the entry into force of the policy), participants evaluated the labels with warnings again (T2). Data were analyzed using content analysis. At T1, when labels were presented without nutritional warnings, responses to the word association task were related to a description of the product category, expected sensory characteristics of the products, brand names, liking and eating occasions. However, when the labels were presented with the warnings at T2, a significant increase in the frequency of mention of responses was observed within the categories Excessive content of sugar/fat/sodium, Not healthy, Diseases and negative health conditions, Rejection to consume, and Unexpected information. Results from the present work suggest that immediately after their implementation, nutritional warnings cause a salience bias that make excessive nutrient content and its negative health consequences more salient in consumers&rsquo; minds, especially in the case of products with a particular health-related connotation.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Ares, Gast&oacute;n</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ant&uacute;nez, Luc&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Otterbring, Tobias</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Curutchet, Mar&iacute;a Rosa</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Galicia, Luis</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Moratorio, Ximena</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bove, Isabel</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Food Quality and Preference v. 86, 2020. -- p. 1-5.--e103991]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&ntilde;iculo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.1016/j.foodqual.2020.103991" target="_blank">https://doi.org/10.1016/j.foodqual.2020.103991</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6093">
    <dcterms:title><![CDATA[<strong>Avoiding household food waste, one step at a time The role of self-efficacy, convenience orientation, and the good provider identity in distinct situational contexts</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ALIMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[DESPERDICIO DE ALIMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[A primary cause of food waste in households is a lack of food capabilities. Yet, the antecedents of food capabilities and its relationship with causes of food waste across different situational contexts remain poorly understood. We apply self‐efficacy theory in combination with convenience orientation and good provider identity in a mixed‐methods study. Findings reveal that the sequential structure of self‐efficacy explains how capabilities contribute to food waste avoidance. A good provider identity, however, increases food waste, and also turns out to further convenience orientation. Food capabilities, in turn, reduce convenience orientation. Qualitative insights shed light on consumer's own accounts of their abilities. The findings contribute to a theory‐based understanding of how consumers manage the complex issue of food waste. Findings imply that public policy and marketing should aim to strengthen consumers' self‐efficacy beliefs and redefine the good provider identity, in particular in social contexts, to reverse its effect on waste.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Aschemann-Witzel, Jessica</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gim&eacute;nez, Ana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gr&oslash;nh&oslash;j, Alice</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ares, Gast&oacute;n</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Consumers Affairs. v. 54, 2020. --p. 581-606]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley Online Library]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.1111/joca.12291" target="_blank">https://doi.org/10.1111/joca.12291</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6094">
    <dcterms:title><![CDATA[<strong>Genetic markers that could influence clinical decision making during treatment with methotrexate</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[TOXICIDAD]]></dcterms:subject>
    <dcterms:subject><![CDATA[FARMACOGENOMICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[METOTREXATO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[No tiene Abstract]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Esperon, Patricia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Giletti, Andrea</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Pharmacogenomics. v. 21, no. 8, 2020. -- p.505-507]]></dcterms:source>
    <dcterms:publisher><![CDATA[Future Medicine]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.2217/pgs-2019-0188" target="_blank">https://doi.org/10.2217/pgs-2019-0188</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6095">
    <dcterms:title><![CDATA[<strong>SVECV-F12: A Composite Scheme for an Accurate and Cost Effective Evaluation of Reaction Barriers. I. Benchmarking Using the HTBH38/08 and NHTBH38/08 Barrier Heights Databases</strong>
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:title>
    <dcterms:subject><![CDATA[BENCHMARKING
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESTADOS DE TRANSICION
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[REACCIONES QUIMICAS
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:subject>
    <dcterms:abstract><![CDATA[A simple version of a composite scheme is described, based on a combination of density functional geometry and frequencies evaluation, valence energies obtained using the CCSD(T)-f12 method extrapolated to the complete basis set limit, and core-valence correlation corrections employing the MP2 method. The procedure was applied to the 38 reactions in Truhlar&rsquo;s HTBH38/08 and NHTBH38/08 databases. Mean unsigned deviation (MUD) for the complete set of 68 independent barriers is 0.43 kcal mol-1, compared to 1.37 kcal/mol for G4 and 1.69 kcal/mol for the dispersioncorrected M06-2X method. Its accuracy is also better that that of other calculations using composite methods of similar cost. The MUD of the new scheme on the barriers in the DBH24/08 subset (12 out of the 38 reactions in both other sets) is 0.31 kcal mol-1, better than that obtained at the expensive CCSD(T,full)/aug-cc-pCV(T+d)Z level (0.46 kcal mol-1) and comparable to the most exact (and costly) Wn calculations (MUD=0.14 kcal mol-1). The maximum unsigned deviation (MaxUD) of the new method for all the reactions studied is 1.71 kcal/mol. G4 and M06-2X, on the other side, exhibit MaxUDs of 6.7 and 8.4 kcal/mol respectively
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Ventura, Oscar N.</strong>
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:creator>
    <dcterms:source><![CDATA[ChemRxiv. v.1, 2020. -- p. 1-16.--e11770023<br />
<br />
]]></dcterms:source>
    <dcterms:publisher><![CDATA[ChemRxiv
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISSN : 2573-2293
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6096">
    <dcterms:title><![CDATA[<strong>Kinetics and thermodynamics of the hydroxylation products in the photodegradation of the herbicide Metolachlor</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[HERBICIDAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[CINETICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[TERMOQUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[FOTODEGRADACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[HIDROXILACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Electronic structure calculations have been performed to determine the thermochemistry and kinetics of the reaction between OH and the radicals of the S enantiomer of the herbicide Metolachlor, 2-chloro-N-(2-methyl-6-ethylphenyl)-N(2-methoxy-1-methylethyl) acetamide (MC), produced by photoinduced breaking of the C&ndash;Cl bond. Both density functional and ab initio composite methods were employed to calculate the structure of reactants, intermediates, transition states and products, in gas phase and in aqueous solution. The expected relative abundance of each product was calculated and compared to the experimentally observed concentrations. It is shown that a combination of thermodynamic and kinetic characteristics interplay to produce the expected theoretical abundances, which turn out to be in agreement with the experimentally observed distribution of products.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Salta, Zoi<br /></strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Kosmas, Agnie M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ventura, Oscar N.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Pure and Applied Chemistry. v.92, no. 3, 2020. -- p. 473-484]]></dcterms:source>
    <dcterms:publisher><![CDATA[De Gruyter]]></dcterms:publisher>
    <dcterms:date><![CDATA[2020]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a title="Art&iacute;culo" href="https://doi.org/10.1515/pac-2018-1205" target="_blank">https://doi.org/10.1515/pac-2018-1205</a>]]></dcterms:identifier>
</rdf:Description></rdf:RDF>
