<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/">
<rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/366">
    <dcterms:title><![CDATA[<strong>The electronic structure of groups of isomeric hetero-aromatic systems : II&mdash;The Spectra and the structure of the N-oxides of benzofurazan (benzofuroxans)</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ESPECTROS ELECTRONICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BENZOFURANOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1969]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The electronic spectrum of the benzofurazan-N-oxide and its &mdash;OR, &mdash;NH2 and &mdash;Cl 5- substituted derivatives has been calculated on the assumption that their structure should be on a chargetransfer ion pair (benzofurazane)+ -O&minus; . The agreement with the observed spectrum is very satisfactory; the first absorption band is assigned to an internal charge-transfer transition and the second band to a &pi; &rarr; &pi;* transition.<br />The prediction of the more stable isomeric structure, based on the &pi;-electron energy difference between 1-oxo- and 3-oxo-5-substituted benzofurazans, gives results opposite to the observations reported for &mdash;OMe and &mdash;Cl derivatives. Possible reasons of this failure are discussed.<br /><br />]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Sosa R.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Paoloni, L.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Tetrahedron v. 25, n&ordm;. 18, 1969. -- p. 4197-4205]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[1969]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[http://dx.doi.org/10.1016/S0040-4020(01)82956-2<br /><br />]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3421">
    <dcterms:title><![CDATA[<strong>The Emergence of a New Uruguayan Wine Industry.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[VINO]]></dcterms:subject>
    <dcterms:subject><![CDATA[TECNOLOGIA QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[URUGUAY]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1997]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Although the traditional wine industry of Uruguay is virtually unknown in the international wine market, wine sales are now increasing in some of the most important markets of Europe and North America. Because of strong domestic consumption and a quiescent R&amp;D situation in recent decades, the pioneer vision of high quality that was bom in the 1880s was not realised. The strategy of promoting the typical grape Tannat (Harriague), best known for making high‐quality Madiran reds in southwest France, is starting to result in successful competitive reds which are only found in Uruguay. This paper presents a summary of the history of the Uruguayan wine industry, beginning with the first Tannat vines planted in the 1870s by the Frenchman Harriague, who with a British family developed the most technically advanced winery of those days, including a bacteriological laboratory. With the programme of training for winemakers and the recently started R&amp;D projects in the University of the Republic, it is hoped that the Uruguayan wine industry, based on quality wines at a good price, will continue opening markets and reach its target of 300 000 cases by the year 2000. The country could occupy an interesting position within the quality wines of the Mew World in the near future.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=e2bbd8e658a30ffb5ed00147ebed8a1a"><strong>Carrau, Francisco M</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Wine Research v. 8, no. 3, 1997. -- p. 179-185]]></dcterms:source>
    <dcterms:publisher><![CDATA[Taylor and Francis]]></dcterms:publisher>
    <dcterms:date><![CDATA[1997]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1080/09571269708718118]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/2403">
    <dcterms:title><![CDATA[<strong>The enthalpy of formation of the HSO radical revisited.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[QUIMICA CUANTICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2005]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The enthalpy of formation of the HSO and SOH radicals has been determined employing the CCSD(T) methodology with the aug-cc-pV(X+d)Z basis sets X = D,T,Q,5. Our best estimations are View the MathML source&Delta;Hf,2980(HSO)=-5.2&plusmn;0.5and&Delta;Hf,2980(SOH)=-1.6&plusmn;0.5kcal/mol. The procedure employed to determine those values involves, extrapolation to the CBS limit, a correction for core-valence and relativistic effects. This result is in reasonable agreement with our previous estimations [Int. J. Quant. Chem. 80 (2000) 439] &minus;6.6 and &minus;1.6 kcal/mol for HSO and SOH, respectively. However, it is larger than the lower bound recently estimated by Balucani et al. [JPC. 120 (2004) 9571] &minus;3.0 kcal/mol at 0 K (&minus;3.7 kcal/mol at 298 K).]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=330eeda61de9937431a7182c44a5ee24"><strong>Denis, Pablo A</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chemical Physics Letters v. 402, no. 4-6, 2005. -- p. 289-293]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2005]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
<p>&nbsp;</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[doi:10.1016/j.cplett.2004.12.001]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4809">
    <dcterms:title><![CDATA[<strong>The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I)</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ECHINOCOCCUS GRANULOSUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ENZIMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[TIOREDOXINA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2017]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Aims: New drugs are needed to treat flatworm infections that cause severe human diseases such as schistosomiasis. The unique flatworm enzyme thioredoxin glutathione reductase (TGR), structurally different from the human enzyme, is a key drug target. Structural studies of the flatworm Echinococcus granulosus TGR, free and complexed with AuI-MPO, a novel gold inhibitor, together with inhibition assays were performed. Results: AuI-MPO is a potent TGR inhibitor that achieves 75% inhibition at a 1:1 TGR:Au ratio and efficiently kills E. granulosus in vitro. The structures revealed salient insights: (i) unique monomer&ndash;monomer interactions, (ii) distinct binding sites for thioredoxin and the glutaredoxin (Grx) domain, (iii) a single glutathione disulfide reduction site in the Grx domain, (iv) rotation of the Grx domain toward the Sec-containing redox active site, and (v) a single gold atom bound to Cys519 and Cys573 in the AuI-TGR complex. Structural modeling suggests that these residues are involved in the stabilization of the Sec-containing C-terminus. Consistently, Cys&rarr;Ser mutations in these residues decreased TGR activities. Mass spectroscopy confirmed these cysteines are the primary binding site. Innovation: The identification of a primary site for gold binding and the structural model provide a basis for gold compound optimization through scaffold adjustments. Conclusions: The structural study revealed that TGR functions are achieved not only through a mobile Sec-containing redox center but also by rotation of the Grx domain and distinct binding sites for Grx domain and thioredoxin. The conserved Cys519 and Cys573 residues targeted by gold assist catalysis through stabilization of the Sec-containing redox center. Antioxid. Redox Signal. 27, 1491&ndash;1504.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=8b2cacb0aafc512133624fa7b9bf174c" target="_blank"><strong>Salinas, Gustavo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gao, Wei</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wang, Yang</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bonilla, Mariana.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Yu, Long</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Novikov, Andrei</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Virginio, Veridiana G.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ferreira, Henrique V.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Vieites, Marisol</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gladyshev, Vadim N.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2ff5755f42707a83e7aea75299e5667c" target="_blank"><strong>Gambino, Dinorah.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dai, Shaodong</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Antioxidants &amp; Redox Signaling v. 27, no. 18, 2017. -- p. 1491-1504]]></dcterms:source>
    <dcterms:publisher><![CDATA[Mary Ann Liebert, Inc]]></dcterms:publisher>
    <dcterms:date><![CDATA[2017]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[pdf]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1089/ars.2016.6816]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6261">
    <dcterms:title><![CDATA[<strong>The experience of social distancing for families with children and adolescents during the coronavirus (COVID-19) pandemic in Uruguay: Difficulties and opportunities.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[POLITICAS DE SALUD PUBLICA
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    <dcterms:subject><![CDATA[PRACTICAS DE SALUD PUBLICA
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    <dcterms:subject><![CDATA[CUARENTENA
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    <dcterms:subject><![CDATA[INVESTIGACION CUALITATIVA
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    <dcterms:subject><![CDATA[SINDROME RESPIRATORIO SEVERO
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    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
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    <dcterms:subject><![CDATA[2021
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    <dcterms:abstract><![CDATA[The social distancing measures implemented to contain the coronavirus (COVID-19) pandemic worldwide have created a series of emotional and economic challenges. The aim of the present work was to explore the experiences of families with children and adolescents during the coronavirus (COVID-19) pandemic in Uruguay. An online study was conducted in March 2020 with 1725 parents with children under 18 years old. A series of closed and open-ended questions about their family life since the implementation of social distancing measures were asked, addressing the following topics: how they had felt, changes they had experienced in their daily life, children&rsquo;s daily routine, changes implemented in relation to child-care, changes they had perceived in children&rsquo;s eating patterns, changes in their relationship with their children, changes in their children&rsquo;s mood and behavior, and their reaction to those changes. Results showed that the coronavirus pandemic elicited negative feelings in the majority of participants, mainly related to worry, fear, anxiety and uncertainty. Social distancing measures caused a major disruption in daily habits, which were mostly attributed to changes in work-related activities and the closure of educational institutions. Changes in children&rsquo;s mood and behavior were perceived by the majority of the participants, who mainly referred to boredom, agitation and restlessness. Although some participants reported difficulties to cope with children&rsquo;s behavior during social distancing, others valued the opportunity of spending more time with their children. In terms of children&rsquo;s eating patterns, changes related to both an increase and a decrease in the consumption of healthy foods were observed. Results from the present work have relevant implications for public health policy and practice by highlighting the importance of providing emotional and psychological support to people during social distancing measures and providing insights for the design of communication campaigns and interventions.
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    <dcterms:creator><![CDATA[<strong>Ares, Gast&oacute;n</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bove, Isabel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Vidal, Leticia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Brunet, Ger&oacute;nimo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fuletti, Dar&iacute;o</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Arroyo, Alvaro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Blanc, Mar&iacute;a Victoria</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Children and Youth Services Review v. 121, 2021.--p. 1-10.-- e105906
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    <dcterms:publisher><![CDATA[Elsevier
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    <dcterms:date><![CDATA[2021
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    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> </strong></p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
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    <dcterms:format><![CDATA[Pdf
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    <dcterms:language><![CDATA[Ingl&eacute;s
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    <dcterms:type><![CDATA[Art&iacute;culo
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    <dcterms:identifier><![CDATA[https://doi.org/10.1016/j.childyouth.2020.105906
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</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/1404">
    <dcterms:title><![CDATA[<strong>The extra pharmacopoeia</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[FARMACOPEA]]></dcterms:subject>
    <dcterms:subject><![CDATA[REFERENCIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[QU&Iacute;MICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1895]]></dcterms:subject>
    <dcterms:subject><![CDATA[HISTORIA]]></dcterms:subject>
    <dcterms:creator><![CDATA[<strong>Martindale, W. M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wynn Westcott, W.</strong>]]></dcterms:creator>
    <dcterms:publisher><![CDATA[H. K. Lewis]]></dcterms:publisher>
    <dcterms:date><![CDATA[1895]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /> <br /> (Por favor lea este aviso antes de abrir los documentos u objetos)<br /> <br /> <strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /> <br /> (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /> <br /> <strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[Papel]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Libro]]></dcterms:type>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5816">
    <dcterms:title><![CDATA[<strong>The first enantioselective strategy towards speciosins</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PRODUCTOS NATURALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ENANTIOSELECTIVIDAD]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESPECIOSINA-DERIVADOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2019]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Speciosins constitute a group of natural compounds that have never been synthesized enantioselectively. We propose to introduce chirality by the use of enantiopure 3-halo-cis-1,2-cyclohexadienediols of microbial origin. The introduction of the alkynylic side chain by Sonogashira's methodology was successful, thus confirming a valuable strategy for the asymmetric preparation of speciosins.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Peixoto de Abreu Lima, Alejandro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://exportcvuy.anii.org.uy/CvEstatico/?urlId=a6f6b983eb02f40fe8e9784a71115fd267d30ff3d5997288d688b4c247e99d4e992cc6c5f422970aefe50e0211ce803a6f4322d3eda65e95887a20dd9a4e39fd&amp;formato=pdf&amp;convocatoria=21" target="_self"><strong>Suescun, Leopoldo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwjmuuaz5b_mAhWLIbkGHTpqCzgQFjAAegQIARAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D6bf38ea80d28808107daf59d2aa32b31828dddff08bb4df4bcf2bc571b7f5ea67965bad22f240d27bce7d73b86967173779c3509191945bad0497c895cc06999%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw08nMOYc-Qml9d6xx6DyV9V" target="_self"><strong>Pandolfi, Enrique</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&amp;rct=j&amp;q=&amp;esrc=s&amp;source=web&amp;cd=1&amp;cad=rja&amp;uact=8&amp;ved=2ahUKEwinprnH6L_mAhWeHbkGHfpcDRMQFjAAegQIBBAH&amp;url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3Dea5966be6fa066f73b7d6b9ac4a8e72399239a1aa8a4100a9eeba20d38f6e59d62c828789eee379ae57badbb82671cbaaa35d1faa71944912db693341612abc7%26formato%3Dpdf%26convocatoria%3D21&amp;usg=AOvVaw13u-nC8Q7iBCo2JSw1vDGB" target="_self"><strong>Schapiro, Valeria</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[New Journal of Chemistry v. 43, 2019. -- p. 3653-3655]]></dcterms:source>
    <dcterms:publisher><![CDATA[Royal Society of Chemistry]]></dcterms:publisher>
    <dcterms:date><![CDATA[2019]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1039/C8NJ06158K]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6217">
    <dcterms:title><![CDATA[<strong>The First Use of a ReX5 Synthon to Modulate FeIII Spin Crossover via Supramolecular Halogen&middot;&middot;&middot;Halogen Interactions.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[QUIMICA SUPRAMOLECULAR
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    <dcterms:subject><![CDATA[INTERACCIONES HALOGENAS
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    <dcterms:subject><![CDATA[HALOGENOS
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    <dcterms:subject><![CDATA[OXIDO DE HIERRO
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    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
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    <dcterms:subject><![CDATA[2020
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    <dcterms:abstract><![CDATA[We have added the {ReIVX5}@ (X=Br, Cl) synthon to a pocket-based ligand to provide supramolecular design using halogen&middot;&middot;&middot;halogen interactions within an FeIII system that has the potential to undergo spin crossover (SCO). By removing the solvent from the crystal lattice, we &ldquo;switch on&rdquo; halogen&middot;&middot;&middot;halogen interactions between neighboring molecules, providing a supramolecular cooperative pathway for SCO. Furthermore, changes to the halogen-based interaction allow us to modify the temperature and nature of the SCO event.
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    <dcterms:creator><![CDATA[<strong>Busch, Rebecca</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Carter, Anthony B.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Konidaris, Konstantis F.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>K&uuml;hne, Irina A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gonz&aacute;lez, Ricardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Anson, Christopher E.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Powell, Annie K.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chemistry A European Journal v. 26, 2020. -- p. 11835-11840
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    <dcterms:publisher><![CDATA[Wiley-VCH GmbH
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    <dcterms:date><![CDATA[2020
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    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
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    <dcterms:format><![CDATA[Pdf
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    <dcterms:language><![CDATA[Ingl&eacute;s
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    <dcterms:type><![CDATA[Art&iacute;culo
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    <dcterms:identifier><![CDATA[https://doi.org/10.1002/chem.202001668.
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</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3614">
    <dcterms:title><![CDATA[<strong>The FO2 radical : a new success of density functional theory.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[FO2]]></dcterms:subject>
    <dcterms:subject><![CDATA[DENSIDAD]]></dcterms:subject>
    <dcterms:subject><![CDATA[TEORIA FUNCIONAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1995]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The structure, heat of reaction and heat of formation of the FO2 radical in its X2A&Prime; ground state has been calculated using the three-parameter exchange functional of Becke and the Lee-Yang-Parr functional for correlation energy (B3LYP method). B3LYP geometrical parameters of FO2 and FO are nearer to experiment than those obtained with conventional ab initio calculations. The calculated &Delta;Hr,00 for F + O2 &rarr; FO2 at this level (&minus;11.1 kcal/mol) is nearer to experiment (&minus;11.68 kcal/mol) than that afforded by any other calculation, including QCISD(T), MP4(SDTQ) or G1 ab initio models. Calculation of the heat of reaction for previously considered isodesmic and isogyric reactions involving the FO2 radical shows that the agreement is consistent. The root mean square error for the sixteen reactions considered, involving FO, FO2, FOH and FOOF, with heats of reaction varying from -149 to +56 kcal/mol, is 0.5 kcal/mol at the B3LYP level. The similar rms error for MP4(SDTQ)/6-311+ +G(2d, 2p) calculations is 5.2 kcal/mol. It is concluded that the B3LYP method is faster and more accurate than conventional ab initio methods for the study of reactions involving F-O bonds.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=40f23b501897bd535c01b6602f1ea346"><strong>Ventura, Oscar N</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=af0c20633fe0e9e5e6bc4e2e3c5e8516"><strong>Kieninger, Martina</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chemical Physics Letters v. 245, 1995. -- p. 488-497]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[1995]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Artículo]]></dcterms:type>
    <dcterms:identifier><![CDATA[doi:10.1016/0009-2614(95)01034-7]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4756">
    <dcterms:title><![CDATA[<strong>The genomes of four tapeworm species reveal adaptations to parasitism</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[GENETICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[GENOMAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2013]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat, owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences using the human-infective species Echinococcus multilocularis, E. granulosus, Taenia solium and the laboratory model Hymenolepis microstoma as examples. The 115- to 141-megabase genomes offer insights into the evolution of parasitism. Synteny is maintained with distantly related blood flukes but we find extreme losses of genes and pathways that are ubiquitous in other animals, including 34 homeobox families and several determinants of stem cell fate. Tapeworms have specialized detoxification pathways, metabolism that is finely tuned to rely on nutrients scavenged from their hosts, and species-specific expansions of non-canonical heat shock proteins and families of known antigens. We identify new potential drug targets, including some on which existing pharmaceuticals may act. The genomes provide a rich resource to underpin the development of urgently needed treatments and control.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Tsai, I. J.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Zarowiecki, Magdalena</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Holroyd, N.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Garciarrubio, Alejandro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Sanchez Flores, Alejandro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Brooks, Karen L.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Tracey, A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bobes, R. J.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fragoso, G.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Sciutto, E.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Aslett, M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Beasley, H.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bennett, H. M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cai, J.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Camicia, Federico</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Clark, R.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cucher, Marcela</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>De Silva, N.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Day, T. A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Deplazes, P.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Estrada, K.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=9664a257b8e611abc245a6f6ef902c2a" target="_blank"><strong>Fern&aacute;ndez, Cecilia.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Holland, P. W. H.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Hou, J.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Hu, S.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Brehm, K.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Berriman, M.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Nature v. 496, no. 7443, 2013. -- p. 57-63]]></dcterms:source>
    <dcterms:publisher><![CDATA[Nature]]></dcterms:publisher>
    <dcterms:date><![CDATA[2013]]></dcterms:date>
    <dcterms:rights><![CDATA[<p style="margin-bottom: 0cm;"><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /><br />(Por favor lea este aviso antes de abrir los documentos u objetos)<br /><br /><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /><br />(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /><br /><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[doi:10.1038/nature12031]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/806">
    <dcterms:title><![CDATA[<strong>The graphene nanoribbon : One of the strongest materials</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[FISICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[GRAFENO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2011]]></dcterms:subject>
    <dcterms:subject><![CDATA[LIBROS-ANALITICA]]></dcterms:subject>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=fc7cd71892b1a9968ee19230dafdbd01" target="_blank"><strong>Faccio, Ricardo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=31ed37f6d0196c1ca18c1b4dfab6de76" target="_blank"><strong>Mombru, Alvaro W.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[The Carbon nanoworld : from graphene to nanotubes / Alvaro W. Mombr&uacute;, Mauricio Terrones, eds. -- Kerala : Transworld Research Network , 2011. --&nbsp; p. 23-41]]></dcterms:source>
    <dcterms:publisher><![CDATA[Transworld Research Network]]></dcterms:publisher>
    <dcterms:date><![CDATA[2011]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
<p>&nbsp;</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[Papel]]></dcterms:format>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Cap&iacute;tulo de libro]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISBN : 978-81-7895-516-2]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6158">
    <dcterms:title><![CDATA[<strong>The heuristics that guide healthiness perception of ultra-processed foods: a qualitative exploration</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[POLITICA ALIMENTARIA
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    <dcterms:subject><![CDATA[COMPORTAMIENTO DEL CONSUMIDOR
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    <dcterms:subject><![CDATA[ETIQUETADO
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    <dcterms:subject><![CDATA[EMBALAJE
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    <dcterms:subject><![CDATA[INVESTIGACION CUALITATIVA
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    <dcterms:subject><![CDATA[SALUD
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    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
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    <dcterms:subject><![CDATA[2020]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Objective: To explore the conceptualisation of healthy food by citizens and how they judge the healthiness of ultra-processed foods.<br />Design: Four focus groups were conducted using a semi-structured discussion guide. Focus group discussions were held about the concept of healthy food, what characterise a healthy product and healthiness perception of ultra-processed products.<br />Transcripts of the focus groups were analysed following an inductive coding approach.<br />Setting: Uruguay, one of the Latin American countries with the highest prevalence of overweight and obesity.<br />Participants: Fifty-two adult Uruguayan participants, diverse in terms of gender, age, educational level and socio-economic status.<br />Results: In agreement with previous studies on lay perceptions of healthy eating, the conceptualisation of healthy food was mainly focused on food characteristics.<br />Although participants regarded lack of processing as a cue for healthiness, they did not categorise all ultra-processed products as unhealthy. Albeit some product categories were automatically regarded as unhealthy, participants considered that<br />other categories could include healthy and unhealthy products. In such cases, they<br />explicitly referred to several simplified cognitive strategies to judge whether an ultra-processed product is healthy or not. Results showed that participants tended to rely on simple cues, such as label design, nutrient claims, brand, price and country of origin as indicators of product healthiness.<br />Conclusions: Healthiness perception of ultra-processed products seems to be largely influenced by heuristics, which stresses the need to implement policies that make the potential negative effects of ultra-processed products salient.
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    <dcterms:creator><![CDATA[<strong>Mach&iacute;n, Leandro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ant&uacute;nez, Luc&iacute;a</strong>
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    <dcterms:creator><![CDATA[<strong>Curutchet, Mar&iacute;a Rosa</strong>
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    <dcterms:creator><![CDATA[<strong>Ares, Gast&oacute;n</strong>
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    <dcterms:source><![CDATA[<p>Public Health Nutrition: v. 23, no.16, 2020. -- p. 2932&ndash;2940</p>
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    <dcterms:publisher><![CDATA[Cambridge University Press
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    <dcterms:date><![CDATA[2020
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    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
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    <dcterms:format><![CDATA[Pdf
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    <dcterms:language><![CDATA[Ingl&eacute;s
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    <dcterms:type><![CDATA[Art&iacute;culo
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    <dcterms:identifier><![CDATA[doi:10.1017/S1368980020003158
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</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/1641">
    <dcterms:title><![CDATA[<strong>The high polyphenol content of grapevine cultivar tannat berries is conferred primarily by genes that are not shared with the reference genome</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[VINOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIOXIDANTES]]></dcterms:subject>
    <dcterms:subject><![CDATA[GENOMA]]></dcterms:subject>
    <dcterms:subject><![CDATA[URUGUAY]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPOSICION QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[VINOS TANNAT]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2013]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The grapevine (Vitis vinifera) cultivar Tannat is cultivated mainly in Uruguay for the production of high-quality red wines. Tannat berries have unusually high levels of polyphenolic compounds, producing wines with an intense purple color and remarkable antioxidant properties. We investigated the genetic basis of these important characteristics by sequencing the genome of the Uruguayan Tannat clone UY11 using Illumina technology, followed by a mixture of de novo assembly and iterative mapping onto the PN40024 reference genome. RNA sequencing data for genome reannotation were processed using a combination of reference-guided annotation and de novo transcript assembly, allowing 5901 previously unannotated or unassembled genes to be defined and resulting in the discovery of 1873 genes that were not shared with PN40024. Expression analysis showed that these cultivar-specific genes contributed substantially (up to 81.24%) to the overall expression of enzymes involved in the synthesis of phenolic and polyphenolic compounds that contribute to the unique characteristics of the Tannat berries. The characterization of the Tannat genome therefore indicated that the grapevine reference genome lacks many genes that appear to be relevant for the varietal phenotype.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Da Silva, Cecilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Zamperin, Gianpiero</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ferrarini, Alberto</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Minio, Andrea</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dal Molin, Alessandra</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Venturini, Luca</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Buson, Genny</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Tononi, Paola</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Avanzato, Carla</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Zago, Elisa</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=94eb5bc2376fc85205545a11813c1472" target="_blank"><strong>Boido, Eduardo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="%20%20%20http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2df81feedac99473a4e536d2623f04c3" target="_blank"><strong>Dellacassa, Eduardo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gaggero, Carina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Pezzotti, Mario</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=e2bbd8e658a30ffb5ed00147ebed8a1a" target="_blank"><strong>Carrau, Francisco</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Delledonne, Massimo</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Plant Cell . v.25, no. 12, 2013. -- p. 4777-4788]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Society of Plant Biologists]]></dcterms:publisher>
    <dcterms:date><![CDATA[2013]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[doi:10.1105/tpc.113.118810]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6259">
    <dcterms:title><![CDATA[<strong>The idealisation of bottle feeding: content analysis of feeding bottles and teats packages in Uruguay</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ALIMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ETIQUETADO]]></dcterms:subject>
    <dcterms:subject><![CDATA[LECHE MATERNA-SUSTITUTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[AMAMANTAMIENTO]]></dcterms:subject>
    <dcterms:subject><![CDATA[POLITICA ALIMENTARIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[SALUD PUBLICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2021]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Objective: The information displayed on the packages of feeding bottles and teats commercialised in Montevideo (Uruguay) was analysed using content analysis with the goal of identifying key marketing practices that may discourage breast-feeding. Design: The study was conducted as part of the periodic assessment performed by the Uruguayan government to monitor the marketing of breast milk substitutes. All the feeding bottles and teats sold in forty-four retail outlets selling breast milk substitutes were purchased. The information available on the packages was analysed using content analysis and descriptive statistics. Setting: Montevideo, Uruguay. Results: A total of 197 feeding bottles and 71 teats were found. The majority of the packages included information to enable caregivers to adequately use the products, including recommended age, instructions on how to use the products and instructions on the use of hygienic practices. However, the packages frequently included information that implied that bottle feeding was equivalent to breast-feeding, particularly from a physiological perspective, or that idealised product use. Idealisations included ability to reduce colic, improvements in the feeding experience and improvements in children&rsquo;s health, well-being and development. Statements on the superiority of breast-feeding were infrequent. Conclusions: The results from the present work showed the high prevalence of marketing practices on the packages of feeding bottles and teats that may discourage breast-feeding. Stricter and more detailed regulations seem necessary to enable caregivers to make informed feeding decisions for infants.
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    <dcterms:creator><![CDATA[<strong>Alcaire, Florencia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ant&uacute;nez, Luc&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Vidal, Leticia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>De Le&oacute;n, Carolina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Girona, Alejandra</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez, Raquel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gim&eacute;nez, Ana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bove, Isabel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ares, Gast&oacute;n</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Public Health Nutrition v. 24, no.10, 2021.-- p. 3147&ndash;3155]]></dcterms:source>
    <dcterms:publisher><![CDATA[Cambridge University Press]]></dcterms:publisher>
    <dcterms:date><![CDATA[2021]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos<strong>) La legislaci&oacute;n uruguaya protege el derecho de autor</strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.
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    <dcterms:format><![CDATA[Pdf
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    <dcterms:language><![CDATA[Ingl&eacute;s
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    <dcterms:type><![CDATA[Art&iacute;culo
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    <dcterms:identifier><![CDATA[doi:10.1017/S1368980020004176
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    <dcterms:coverage><![CDATA[URUGUAY]]></dcterms:coverage>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6230">
    <dcterms:title><![CDATA[<strong>The idealization of bottle-feeding: Content analysis of feeding bottles and teats packages in Uruguay</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[LECHE MATERNA
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    <dcterms:subject><![CDATA[LECHE MATERNA-SUSTITUTOS
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    <dcterms:subject><![CDATA[AMAMANTAMIENTO
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    <dcterms:subject><![CDATA[SALUD PUBLICA
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    <dcterms:subject><![CDATA[POLITICA ALIMENTARIA
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    <dcterms:subject><![CDATA[ETIQUETADO
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    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
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    <dcterms:subject><![CDATA[2020
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    <dcterms:abstract><![CDATA[Objective: The information displayed on the packages of feeding bottles and teats commercialized in Montevideo (Uruguay) was analyzed using content analysis with the goal of identifying key marketing practices that may discourage breastfeeding.<br />Design: The study was conducted as part of the periodic assessment performed by the Uruguayan government to monitor the marketing of breast-milk substitutes. All the feeding bottles and teats sold in 44 retail outlets selling breast-milk substitutes were purchased. The information available on the packages was analyzed using content analysis and descriptive statistics.<br />Setting: Montevideo, Uruguay.<br />Results: A total of 197 feeding bottles and 71 teats were found. The majority of the packages included information to enable caregivers to adequately use the products, including recommended age, instructions on how to use the products and instructions on the use of hygienic practices. However, the packages frequently included information that implied that bottle-feeding was equivalent to breastfeeding, particularly from a physiological perspective, or that idealized product use. Idealizations included ability to reduce colic, improvements in the feeding experience and improvements in children&rsquo;s health, wellbeing and development. Statements on the superiority of breastfeeding were infrequent.<br />Conclusions: Results from the present work showed the high prevalence of marketing practices on the packages of feeding bottles and teats that may discourage breastfeeding. Stricter and more detailed regulations seem necessary to enable caregivers to make informed feeding decisions for infants.
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    <dcterms:creator><![CDATA[<strong>Alcaire, Florencia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ant&uacute;nez, Luc&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>De Le&oacute;n, Carolina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Girona, Alejandra</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez, Raquel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gim&eacute;nez, Ana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bove, Isabel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ares, Gast&oacute;n</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Public Health Nutrition, 2020. --p. 1-9 DOI: 10.1017/S1368980020004176
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    <dcterms:publisher><![CDATA[Cambridge University Press
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    <dcterms:date><![CDATA[2020
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    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
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    <dcterms:format><![CDATA[Pdf
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    <dcterms:language><![CDATA[Ingl&eacute;s
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>
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    <dcterms:type><![CDATA[Art&iacute;culo
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    <dcterms:identifier><![CDATA[DOI: 10.1017/S1368980020004176
<div id="sconnect-is-installed" style="display: none;">2.11.0.0</div>
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</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6671">
    <dcterms:title><![CDATA[<strong>The idealization of infant formula: a longitudinal analysis of labels in Uruguay</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[LACTANCIA MATERNA]]></dcterms:subject>
    <dcterms:subject><![CDATA[POLITICA ALIMENTARIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[SUSTITUTOS DE LA LECHE HUMANA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ETIQUETADO]]></dcterms:subject>
    <dcterms:subject><![CDATA[ALIMENTACI&Oacute;N ARTIFICIAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2023]]></dcterms:subject>
    <dcterms:abstract><![CDATA[<span style="text-decoration: underline;">Background:</span> Labels are a key element of the marketing strategies of infant formula companies, and often include text or images that idealize their use, undermining efforts to promote breastfeeding. <span style="text-decoration: underline;">Research Aims:</span> To evaluate the prevalence of marketing cues that idealize infant formula on labels of products commercialized in Uruguay and to assess changes after a periodic monitoring of compliance with the International Code of Marketing of Breast-Milk Substitutes (IC). <span style="text-decoration: underline;">Method:</span> This study is a descriptive, observational, and longitudinal assessment of the information included on infant formula labels. The first data collection was in 2019, as part of a periodic assessment to monitor the marketing of human-milk substitutes. In 2021, the same products were purchased to evaluate changes in their labels. Thirty-eight products were identified in 2019, of which 33 were still available in 2021. All information available on the labels was analyzed through content analysis. <span style="text-decoration: underline;">Results:</span> Most products included at least one textual or visual marketing cue idealizing infant formula in both 2019 (n=30, 91%) and 2021 (n=29, 88%). This represents a violation of both the IC and national regulations. References to nutritional composition were the most frequent marketing cue, followed by references to child growth and development. No relevant changes were observed after the periodic assessment conducted by the Uruguayan government. <span style="text-decoration: underline;">Conclusions:</span> Monitoring compliance with the IC per se cannot be expected to trigger changes in the marketing strategies of infant formula companies. More explicit regulations and strong enforcement mechanisms are needed to end the inappropriate marketing practices on infant formula labels.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez, Raquel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>de Le&oacute;n, Carolina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Girona, Alejandra</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://export.cvuy.uy/cv/?1d1634f06483fefa7e198e5fc218a4e8529e9ed3339d10137b503d01243da35a8648d3f2ae41594fbc6936e7698ce46fc461e4f0095ea4718c46be55b35410df" target="_blank"><strong>Alcaire, Florencia</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://export.cvuy.uy/cv/?7dd276e2441870ffa17f20a0b26e1c6d1f5d2bf6d0e6bdc40832dca4787f1ea7e26c717086e07a5df1b47e258b828694cf34bd7bd13348216c403d4897e7969e" target="_blank"><strong>Ant&uacute;nez, Luc&iacute;a</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://export.cvuy.uy/cv/?e41ee09b825f22635cb8a1e9b42b334d75d1c2be0ccaad4f086d148a0ebac442b4a82cfb05ef977a8fe31965e28ee4bb8889f1ccb549f56f20a9403e2c02a0cf" target="_blank"><strong>Ares, Gast&oacute;n</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://export.cvuy.uy/cv/?e13bee77c03cddbef59b397e314055a6622de73c70417f3162757bfad754bfa8ad01125204736ed535ca050230cfa514a6e43d3d2464b7fea2cb77f4995d0c4b" target="_blank"><strong>Vidal, Leticia</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Human Lactation, v.39, n&deg;3, 2023. -- pp. 519-528]]></dcterms:source>
    <dcterms:publisher><![CDATA[<span>&nbsp;International Lactation Consultant Association</span>]]></dcterms:publisher>
    <dcterms:date><![CDATA[2023]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong>&nbsp;de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:extent><![CDATA[10 p.]]></dcterms:extent>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[10.1177/08903344231172478]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/2588">
    <dcterms:title><![CDATA[<strong>The immunogenicity of Echinococcus granulosus antigen 5 is determined by its post translational modifications.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PARASITOLOGIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ECHINOCOCCUS GRANULOSUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2005]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Since its early introduction as a marker for the immunodiagnosis of hydatid disease, antigen 5 (Ag5) has been regarded as one of the more relevant antigens of Echinococcus granulosus, and it is still widely used in different confirmation techniques. In this work we prepared 2 recombinant forms of the antigen, namely, rAg5 (corresponding to the unprocessed polypeptide chain of the antigen) and rAg5-38s (corresponding to its 38 kDa subunit). Their antigenicities were compared to that of the native antigen using a human serum collection. There was a major drop in the reactivity of the sera, particularly against rAg5-38s, which was confirmed by analysis of the cross-reactivity of 2 panels of monoclonal antibodies specific for rAg5-38s and the native antigen. Using the chemically deglycosylated native antigen, we demonstrated that the reduced antigenicity of the recombinants is due to the loss of the sugar determinants, and not to their misfolding. Inhibition experiments using phosphorylcholine confirmed that this moiety also contributes to the reactivity of the antigen, but to a much lesser extent. The presence of immunodominant highly cross-reactive glycan moieties in the Ag5 molecule may involve a parasite evasion mechanism.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Lorenzo, C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=7ee0def1187be47e0710e877d9768b5a"><strong>Gonz&aacute;lez-Sapienza, Gualberto G.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Last, J.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Parasitology v. 131, no. 5, 2005. -- p. 669-677]]></dcterms:source>
    <dcterms:publisher><![CDATA[Cambridge]]></dcterms:publisher>
    <dcterms:date><![CDATA[2005]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[doi:10.1017/S0031182005008309]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3957">
    <dcterms:title><![CDATA[<strong>The impact of different baking conditions on the stability of the extractable polyphenols in muf fi ns enriched by strawberry, sour cherry, raspberry or black currant pomace.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[POLIFENOLES]]></dcterms:subject>
    <dcterms:subject><![CDATA[GLUCOSIDOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[FLAVONOLES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESTABILIDAD]]></dcterms:subject>
    <dcterms:subject><![CDATA[FRUTAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTOCIANINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2016]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The stability of polyphenols in muffins, enriched with strawberry, black currant, raspberry and sour cherry pomace (50 g/kg), baked in a conventional and halogen oven, at three different temperatures (140, 180 and 220 C), was studied. The most unstable compounds were anthocyanins (36e97% lost), in contrast the flavonol glycosides were the most stable (0e21% lost). Over 100% recovery was observed for neochlorogenic acid and ellagic acid (95e120% and 341e823%, respectively). The increase of free ellagic acid content in muffins enriched with strawberry or raspberry was positively correlated with the baking time (r &frac14; 0.879 and r &frac14; 0.944, respectively) and was the result of thermal hydrolysis of ellagitannins and ellagic acid glycosides. The highest temperature combined with a short baking time had the best effect on the preservation of polyphenols, however, since the polyphenol composition can be expected to vary in different fruits, each case should be considered separately, in order to achieve the most favorable nutritional effect of baked products enriched with fruit pomace. The sensory evaluation showed that muffins enriched with 50 g/kg of fruit pomace were competitive with control muffins, with the added benefit of having a higher nutritional value.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Gorn&aacute;s, Pawel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Juhnevica-Radenkova, Karina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Radenkovs, Vitalijs</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Misina, Inga</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Pugajeva, Iveta</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Soliven, Arianne</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Seglina, Dalija</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[LWT - Food Science and Technology v. 65, 2016. -- p. 946-953]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2016]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[http://dx.doi.org/10.1016/j.lwt.2015.09.029]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6324">
    <dcterms:title><![CDATA[<strong>The impact of Hanseniaspora vineae fermentation and ageing on lees on the terpenic aromatic profile of white wines of the albillo variety</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[VINOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[HANSENIASPORA VINEAE]]></dcterms:subject>
    <dcterms:subject><![CDATA[LEVADURAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[FERMENTACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[TERPENOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[POLISACARIDOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2021]]></dcterms:subject>
    <dcterms:abstract><![CDATA[<p>Hanseniaspora vineae is a non-Saccharomyces yeast that has a powerful impact on the sensory profile of wines. Its effect on the aromatic profile of non-aromatic grape varieties, such as Albillo Mayor (Vitis vinifera, L.), during vinification is a useful biotechnology to improve sensory complexity. Fermentation in steel barrels using Hanseniaspora vineae and sequential inoculation with Saccharomyces cerevisiae have been used to study the formation of terpenes and cell lysis in the production of Albillo white wines. The GC-MS analysis profile shows a significant effect of H. vineae fermentation on the contents of terpenes (3), mainly in linalool (&gt;3), -citronellol (&gt;4), geraniol (&gt;2) and-terpineol (2). The contents of several polyoxygenated terpenes and some volatile phenols with a spicy aroma were increased during fermentation. In summary, Hanseniaspora vineae releases a large number of cell wall polysaccharides during fermentation that affect wine palatability and structure.<br />Hanseniaspora vineae is a powerful bio-tool to enhance the fruitiness, floral notes and freshness in non-aromatic white varieties.</p>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Fresno, Juan Manuel del</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Escott, Carlos</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Loira, Iris</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cv/?8ccb5adf5e034ef96c0a125b78ad413aa3342b85ebd78407b9942af62fa2cbca3bb99b7ba8a494b83c813ecac54cfcd67c603a8f425ba0d9961d03d7c2f8d777" target="_blank"><strong>Carrau, Francisco</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cuerda, Rafael</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Schneider, R&eacute;mi</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ba&ntilde;uelos, Mar&iacute;a Antonia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gonz&aacute;lez, Carmen</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Su&aacute;rez Lepe, Jos&eacute; Antonio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Morata, Antonio</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[International journal of molecular sciences&nbsp;v. 22,&nbsp;n&deg; 4,&nbsp; 2021.p. 1-14. -- e22042195]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2021]]></dcterms:date>
    <dcterms:rights><![CDATA[<strong>Informaci&oacute;n sobre Derechos de Autor</strong>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya&nbsp;protege el derecho de autor</strong> sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong>&nbsp;- La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span>&nbsp;</span><a href="https://doi.org/10.3390/ijms22042195">https://doi.org/10.3390/ijms22042195</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/2830">
    <dcterms:title><![CDATA[<strong>The impact of international exchange : the scientific journey of Marini Bettolo from Italy to Uruguay.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[HISTORIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[PUBLICACIONES]]></dcterms:subject>
    <dcterms:subject><![CDATA[MARINI BETTOLO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2004]]></dcterms:subject>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=1424ef7476f5da983ef6cd034fcf13fe"><strong>Moyna, Patrick</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chemistry International v. 26, no. 2, 2004]]></dcterms:source>
    <dcterms:publisher><![CDATA[IUPAC]]></dcterms:publisher>
    <dcterms:date><![CDATA[2004]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISSN: 1365-2192]]></dcterms:identifier>
    <dcterms:coverage><![CDATA[Uruguay]]></dcterms:coverage>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6527">
    <dcterms:title><![CDATA[<strong>The impact of nutritional warnings on the mental associations raised by advertisements featuring ultra-processed food products</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ADVERTENCIAS NUTRICIONALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ETIQUETADO]]></dcterms:subject>
    <dcterms:subject><![CDATA[NUTRICION]]></dcterms:subject>
    <dcterms:subject><![CDATA[POLITICA ALIMENTARIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ALIMENTOS ULTRAPROCESADOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2022]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Governments worldwide are increasingly mandating the inclusion of graphic and textual warnings on the packages and advertisements of processed products with high content of nutrients associated with noncommunicable diseases (NCDs). The aim of the present study was to assess the impact of nutritional warnings on the mental associations raised by advertisements featuring ultra-processed products. An online experiment was performed with a convenience sample of 380 Uruguayan participants. Participants were exposed to either<br />control advertisements or advertisements featuring black octagonal nutritional warnings. Right after watching the advertisements, they were asked to complete a word association task. Responses were grouped into 20 categories following inductive coding. A generalized linear model was used to assess the effect of experimental condition on the likelihood of providing responses within each of the identified categories. Participants exposed to the advertisements with (vs. without) warnings were more likely to provide responses related to NCDs or nutritional warnings. Meanwhile, no significant differences were found in the frequency of mention of categories related to sensory, hedonic, emotional, or social aspects linked to consuming the products between participants<br />exposed to advertisements with and without warnings. These results suggest that nutritional warnings may be a promising strategy to make consumers aware of the nutritional characteristics of ultra-processed products without affecting the ability of advertisements to convey their intended message.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>P&eacute;rez, Luc&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ant&uacute;nez, Luc&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Otterbring, Tobias</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cv/?e41ee09b825f22635cb8a1e9b42b334d75d1c2be0ccaad4f086d148a0ebac442b4a82cfb05ef977a8fe31965e28ee4bb8889f1ccb549f56f20a9403e2c02a0cf"><strong>Ares, Gast&oacute;n</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Food Quality and Preference, v.101, 2022. -- e104648]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2022]]></dcterms:date>
    <dcterms:rights><![CDATA[<div class="element-text">
<div class="element-text">
<p><span><strong>Informaci&oacute;n sobre Derechos de Autor</strong></span></p>
<p><span>(Por favor lea este aviso antes de abrir los documentos u objetos)</span></p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho de autor</strong><span>&nbsp;sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</span></p>
<p><strong>ADVERTENCIA:</strong><span>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</span></p>
</div>
</div>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[10.1016/j.foodqual.2022.104648]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6460">
    <dcterms:title><![CDATA[<strong>The impact of sensory attributes of mandarins on consumer perception and preferences</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[MANDARINA]]></dcterms:subject>
    <dcterms:subject><![CDATA[PERFIL SENSORIAL]]></dcterms:subject>
    <dcterms:subject><![CDATA[CONSUMIDORES]]></dcterms:subject>
    <dcterms:subject><![CDATA[CATA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2021]]></dcterms:subject>
    <dcterms:abstract><![CDATA[<p>Although the sensory characterization of mandarins has usually been performed by trained assessors, in recent years, the methodologies that depict sensory descriptions from the perception of consumers, such as the checkall- that-apply (CATA) questionnaires have become very popular. In this work, an exploratory study was first carried out using a focus group (FG) technique to determine attributes and aspects that influence the decision to purchase mandarins. Secondly, the consumer panel recruited 100 regular mandarin consumers that were randomly divided into two groups. Group &ldquo;A&rdquo; received segments of 15 mandarins. Group &ldquo;B&rdquo;, instead of receiving the same mandarins in segments, they received them as a whole fruit having to peel them by themselves. Both groups evaluated the total acceptability with a 9-point hedonic scale and answered a CATA questionnaire composed of 38 terms for Group &ldquo;A&rdquo; and 52 terms for Group &ldquo;B&rdquo;. Although the consumers in the FG described an "ideal" mandarin as easy-to-peel, no significant difference (p &gt; 0.05) was found in the acceptability<br />between groups &ldquo;A&rdquo; and &ldquo;B&rdquo;. Characteristics such as sweet, very sweet, fresh smell, sweet smell, bright, fruity taste, fresh flavor, typical flavor, balanced taste and nice flavor were strongly and positively correlated with overall consumers&rsquo; acceptance.</p>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cvsni/?urlId=9e0226832c58b76dfe35556298c9ffe5965c331085e652b1ea024ab73ead6296bf151c5e3e17d95e2ba698422846702e67f3356835059c00f94c1edcd55e4f85&amp;convocatoria=21&amp;formato=html" target="_blank"><strong>G&aacute;mbaro, Adriana</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Roascio, Antonella</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Hodos, Natalia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cv/?4e8790094627dcd20f1718b9bf2b88bd8cea40a68b525e30bf109dc94f7fdba2109c0cf4034470b0b4d5a9f44c2bfe194152e221dd5805d9671e99e3c1a2a2d2" target="_blank"><strong>Migues, Ignacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lado Lindner, Joanna</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cvsni/?urlId=efdc2e4d27c46568e51501a117c8d64c661d28215277fe2b1621ea4a392338f0bd55c3b410eb66c8bd85997e02d92a5828f529ff076bd0478d3b4ffd01ec2037&amp;convocatoria=21&amp;formato=html" target="_blank"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rivas, Carlos Fernando</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Agriculture and Food Research,&nbsp;v. 6, 2021. -- e100196]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2021]]></dcterms:date>
    <dcterms:rights><![CDATA[<p dir="ltr"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p dir="ltr">(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p dir="ltr"><strong>La legislaci&oacute;n uruguaya protege el derechode autor</strong>&nbsp;sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"><strong>ADVERTENCIA:</strong>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</span>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<p align="JUSTIFY"><span style="color: #000000;"><span><span style="font-family: Arial, sans-serif;"><span style="font-size: small;"><span><span><span>10.1016/j.jafr.2021.100196 </span></span></span></span></span></span></span></p>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5275">
    <dcterms:title><![CDATA[<strong>The Impact of Solid Dispersion on Formulation, Using Confocal Micro Raman Spectroscopy as Tool to Probe Distribution of Components</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[DISPERSION SOLIDA]]></dcterms:subject>
    <dcterms:subject><![CDATA[FORMULACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESPECTROSCOPIA RAMAN]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2018]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Purpose Solid dispersions (SDs) of a poorly water-soluble drug were prepared, and their physicochemical properties were compared to those of control physical mixtures (PMs). Among the multiple techniques used to characterize the solid state of preparations, confocal micro Raman spectroscopy (CMRS) was used as a non-destructive tool to qualitatively probe content uniformity and distribution of drug and carrier. Methods SDs and PMs of drug (fenbendazole, FBZ) were prepared containing two different carriers (poloxamer P188 or P407) with different drug polymer ratios. The preparations were characterized by powder X-ray diffractometry, Fourier transform infrared spectroscopy, thermal analysis, scanning electron microscopy, and in vitro dissolution assay. In addition, CMRS technique and principal component analysis (PCA) were used in order to statistically define the content uniformity and distribution of the drug within the polymeric matrix. Results In vitro dissolution results exhibited a marked improvement when the drug was formulated as SD compared to control PM and to pure drug. The solid state of these preparations characterized by X-ray powder diffraction and Fourier transform infrared spectroscopy showed no changes in the crystalline state of the drug and no chemical interactions between the components. Raman studies showed a better content uniformity of the drug within the polymeric matrix when subjected to SD process, correlating with the improved dissolution profile. Conclusion This study provides evidence of the potential of the confocal Raman imaging technique, providing a fast and powerful method to characterize solid dispersions which could be incorporated towards the use of quality by design (QbD) approaches in pharmaceutical development.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Melian, M. Elisa</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Mungu&iacute;a, A. Beatriz</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=fc7cd71892b1a9968ee19230dafdbd01" target="_blank"><strong>Faccio, Ricardo.</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Palma, Santiago</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curiculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=ae579f47d769d2ed742a6a34064041f6" target="_blank"><strong>Dom&iacute;nguez, Laura.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Pharmaceutical Innovation |g v. 13, 2018. -- p. 58-68]]></dcterms:source>
    <dcterms:publisher><![CDATA[Springer]]></dcterms:publisher>
    <dcterms:date><![CDATA[2018]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3181">
    <dcterms:title><![CDATA[<strong>The Incidence and Economic Significance of Ovine Toxoplasmosis in Uruguay.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[OVINOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[URUGUAY]]></dcterms:subject>
    <dcterms:subject><![CDATA[TOXOPLASMOSIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ECONOMIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1999]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Antibodies to Toxoplasma gondii were measured before and after pregnancy in a 1:64 dilution of sera with the direct agglutination test in 1613 ewes from 18 farms in 8 different counties of Uruguay from 1992 to 1994. The overall seroprevalence increased from 28.7% before mating to 38.5% after lambing in 2.5 yr and thus, the incidence was 9.8%. Losses due to toxoplasmosis during pregnancy were estimated to be 1.4 to 3.9% of the total number of ewes investigated, amounting to approximately US$1.4&ndash;4.7 million for the whole country.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Freyre, Alvaro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bonino, J</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Falc&oacute;n, J</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Castells, D</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Correa, O</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Casaretto, A</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Veterinary Parasitology v. 81, , 1999. -- p. 85-88]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[1999]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[doi:10.1016/S0304-4017(97)00069-1]]></dcterms:identifier>
    <dcterms:coverage><![CDATA[Uruguay]]></dcterms:coverage>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6758">
    <dcterms:title><![CDATA[<strong>The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PARASITOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[INFECCIONES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIPARASITARIOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2023]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Severe infections with potentially fatal outcomes are caused by parasites from the genera Trypanosoma and Leishmania (class Kinetoplastea). The diseases affect people of remote areas in the tropics and subtropics with limited access to adequate health care. Besides insufficient diagnostics, treatment options are limited, with tenuous developments in recent years. Therefore, new antitrypanosomal antiinfectives are required to fight these maladies. In the presented approach, new compounds were developed and tested on the target trypa nothione synthetase (TryS). This enzyme is crucial to the kinetoplastids&rsquo; unique trypa nothione-based thiol redox metabolism and thus for pathogen survival. Preceding studies have shown that N5 -substituted paullones display antitrypanosomal activity as well as TryS inhibition. Herein, this compound class was further examined regarding the structure-activity relationships (SAR). Diverse benzazepinone derivatives were designed and tested in cell based assays on bloodstream Trypanosoma brucei brucei (T. b. brucei) and intracellular amastigotes of Leishmania infantum (L. infantum) as well as in enzyme-based assays on L. infantum TryS (LiTryS) and T. b. brucei TryS (TbTryS). While an exchange of just the sub stituent in the 9-position of paullones led to potent inhibitors on LiTryS and T. b. brucei para sites, new compounds lacking the indole moiety showed a total loss of activity in both assays. Conclusively, the indole as part of the paullone structure is pivotal for keeping the TryS inhibitory and antitrypanosomal activity of this substance class.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Ihnatenko, Irina</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>M&uuml;ller, Marco J.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Orban, Oliver C. F.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lindhof, Jens C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ben&iacute;tez, Diego</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ort&iacute;z, Cecilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dibello, Estefan&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Seidl, Leonardo L.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Comini, Marcelo A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Kunick, Conrad</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[PloS one, v.18, n&deg;11, 2023. -- e0292946]]></dcterms:source>
    <dcterms:publisher><![CDATA[PLOS]]></dcterms:publisher>
    <dcterms:date><![CDATA[2023]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong>&nbsp;de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:extent><![CDATA[58 p.]]></dcterms:extent>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[10.1371/journal. pone.0292946]]></dcterms:identifier>
</rdf:Description></rdf:RDF>
