Metabolic engineered E. coli for the production of (R)-1,2-propanediol from biodiesel derived glycerol]]> Rodríguez Giordano, Sonia]]>

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La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)

ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.

]]> Synthetic Study of 5-Hydroxymethylfurfural in Groebke-Blackburn-Bienaymé Reaction]]> de la Sovera, Victoria]]> López, Gloria V.]]> Porcal, Williams]]>

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ADVERTENCIA: La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.

]]> Synthesis of Pyrethroids and Jasmonoids through Palladium-Catalyzed Cross-Coupling Reactions]]> Parpal, Florencia]]> Paullier, Ana Paula]]> Pandolfi, Enrique]]> Heguaburu, Viviana]]>

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]]> Methanogenic community linked to organic acids fermentation from root exudates are affected by rice intensification in rotational soil systems]]> Pereira Mora, Luciana]]> Terra, José A.]]> Fernández Scavino, Ana]]>

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]]> Season and No-Till Rice Crop Intensification Affect Soil Microbial Populations Involved in CH4 and N2O Emissions]]> Fernández Scavino, Ana]]> Oreggioni, Daniela]]> Martínez Pereyra, Andrea]]> Tarlera, Silvana]]> Terra, José A.]]> Irisarri, María del Pilar]]>

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]]> Can children use the A-not a test?]]> results. A total of 126 children were involved in the study. They participated in three sessions, each composed of a familiarization task with a visual stimuli and sample tasting with
one of three dairy products (vanilla milk desserts, chocolate-flavored milk, and vanillaflavored yogurt). Half of the children evaluated the samples in terms of overall differences and the other half in terms of differences in liking. Results from the familiarization step showed that children correctly identified the visual reference in the A-not-A test regardless of how the question was framed, suggesting that they were able to understand the methodology. In the case of tasting samples, children were significantly more likely to correctly identify the reference in two of the three studied dairy products, when the question was based on liking, as compared to the framing based on overall differences.]]> Velázquez, Ana Laura]]> Vidal, Leticia]]> Varela, Paula]]> Ares, Gastón]]> Información sobre Derechos de Autor

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]]> Secretion and detection of defensive compounds by the red flour beetle tribolium castaneum interacting with the insect pathogenic fungus beauveria bassiana]]> Información sobre Derechos de Autor

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]]> Phylogeny and identification of pantoea species associated with bulb rot and bacterial leaf blight of onion crops in Uruguay]]> Pantoea spp. isolates was obtained (11 from bulbs and 48 from leaves and seeds-stalks). Multilocus sequence analysis using four housekeeping genes (rpoB, gyrB, leuS, and fusA) allowed the assignment of the isolates to five Pantoea species: P. ananatis, P. agglomerans, P. allii, P. eucalypti, and P. vagans. The last two species were not previously reported as onion pathogens elsewhere. The ability to cause disease symptoms was tested by leaf inoculation and red onion scale assays. P. ananatis isolates showed the highest aggressiveness in both assays. Specific isolates from P. allii (MAI 6022), P. eucalypti (MAI 6036), P. vagans (MAI 6050), and Pantoea sp. (MAI 6049) ranked second in aggressiveness on onion leaves, whereas only three isolates belonging to P. eucalypti (MAI 6036 and MAI 6058) and P. agglomerans (MAI 6045) exhibited the same scale-clearing phenotype as P. ananatis. Leaf inoculation assays were also performed on a set of eight onion cultivars and breeding lines. Overall, P. ananatis MAI 6032 showed the highest aggressiveness in all tested cultivars, followed by P. eucalypti MAI 6036. The presence of new reported bacterial species leads to complex disease management and highlights the need for further studies on virulence factors and the epidemiology of these pathogens.]]> De Armas, Stefanie]]> Galván, Guillermo A.]]> Lapaz, María I.]]> González Barrios, Pablo]]> Vicente, Esteban]]> Pianzzola, María J.]]> Siri, María I.]]> Información sobre Derechos de Autor

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]]> Sensitivity of Haemonchus contortus to anthelmintics using different in vitro screening assays: a comparative study]]> Background: Helminthiasis and resistance to commercial anthelmintic compounds are major causes of economic
losses for livestock producers, resulting in an urgent need for new drugs and reliable in vitro screening tests capable
of detecting potentially active products. Considering this, a series of novel benzimidazole derivatives (5-methylbenzimidazole 1,2-disubstituted, 5-carboxybenzimidazole, 5-methylbenzimidazole 2-one) was screened on exsheathed L3 (xL3) and on the adult stage of Haemonchus contortus (Kirby anthelmintic-susceptible McMaster isolate).
Methods: This work presents the set-up of an automated motility assay on the xL3 stage of H. contortus using an
infrared tracking device (WMicrotracker One) together with a larval development test (xL3 to L4) and a motility assay
on the adult stage of H. contortus. A comparative study of the sensitivity of these in vitro assays using commercial
anthelmintics with different mechanisms of action was carried out, also evaluating anthelmintic activity of a series of
novel benzimidazole derivatives.
Results: The automated xL3 assay had the great advantage of being able to analyze many compounds simultaneously,
but it showed the limitation of having lower sensitivity, requiring higher concentrations of the commercial
anthelmintics tested compared to those needed for the adult motility or development assays. Although none of the
novel 1,2,5-tri-substituted benzimidazole derivatives could significantly decrease the motility of xL3s, one of them (1e)
significantly affected the development of xL3s to L4, and five new compounds (1b, 1d, 1e, 2a and 2c) reduced the
motility of H. contortus adult stage.
Conclusions: The analysis of the results strongly suggests that the in vitro xL3 to L4 development test, particularly
for the L4 stage, could be closer to the pharmacological sensitivity of the adult stage of H. contortus (target of interest)
for commercial anthelmintic selected, with different mechanisms of action, and for the series of benzimidazole
derivatives assayed. Therefore, an automated motility assay on L4 using the infrared tracking device is being set up.
Further studies will be conducted to evaluate the in vivo anthelmintic activity of the most active novel benzimidazole
derivatives.

]]> Munguía, Beatriz]]> Saldaña, Jenny]]> Nieves, Magdalena]]> Melian, María Elisa]]> Ferrer, Manuela]]> Teixeira, Ramiro]]> Porcal, Williams]]> Manta, Eduardo]]> Domínguez, Laura]]> BioMed Central]]> Información sobre Derechos de Autor

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]]> Diversity and effect of increasing temperature on the activity of methanotrophs in sediments of fildes Peninsula Freshwater Lakes, King George Island, Antarctica]]> temperature on the CH4 oxidation potential in sediments of freshwater lakes in polar regions of the southern hemisphere.]]> Roldán, Diego M.]]> Carrizo, Daniel]]> Sánchez García, Laura]]> Menes, Rodolfo Javier]]> Información sobre Derechos de Autor

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]]> Structure elucidation of Triterpenoid Saponins found in an immunoadjuvant preparation of Quillaja brasiliensis using mass spectrometry and 1H and 13C NMR spectroscopy]]> Wallace, Federico]]> Fontana, Carolina]]> Ferreira, Fernando]]> Olivaro, Cristina]]> Información sobre Derechos de Autor

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]]> Hybrid Organic-Inorganic materials and Interfaces with mixed Ionic-Electronic transport properties: advances in experimental and theoretical approaches]]> Romero, Mariano]]> Mombrú, Dominique]]> Pignanelli, Fernando]]> Faccio, Ricardo]]> Mombrú, Álvaro W.]]> Información sobre Derechos de Autor

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]]> Multiresidue analysis of basic, neutral, and acidic pesticides in biobeds’ biomixture]]> Contain between 1 and 3 bullet points highlighting the customization rather than the steps of the procedure. An analytical methodology was adjusted and validated for the analysis of 15 selected pesticides currently employed in extensive agriculture. The main application of this methodology is studying the pesticides degradation behavior using biobeds as a friendly environmental tool for the treatment of wastewaters generated in fields. The scope of the method was selected based on the most used pesticides in soybean crops in Uruguay. The novelty of this work is the inclusion of neutral and acidic herbicides such as 2,4-D, clethodim, dicamba, together with fungicides and insecticides which are usually included in Multi Residue Methods. An acetonitrile extraction methodology without a clean-up step yielded acceptable results for all the analytes. The instrumental analysis was performed using HPLC-MS/MS. The selected methodology was validated according to the SANTE guidelines. The recoveries were between 65 and 130% with RSD < 20%. The instrumental LOQs were fixed at 1 µg/L for all the compounds except for clethodim, and the method LOQs were 1 mg/kg in biomixture dry basis. These LOQs values are acceptable for biodegradation studies in biobeds.

A multiresidue methodology was:

• Validated for 15 pesticides in biomixture.

• Acidic herbicides were included in the scope.

• The method was employed for the environmental monitoring of pesticide degradation in biobeds.

]]> Rezende, Sofía]]> Besil, Natalia]]> Archondo, Lucas]]> Heinzen, Horacio]]> Cesio, María Verónica]]>

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]]> The impact of nutritional warnings on the mental associations raised by advertisements featuring ultra-processed food products]]> control advertisements or advertisements featuring black octagonal nutritional warnings. Right after watching the advertisements, they were asked to complete a word association task. Responses were grouped into 20 categories following inductive coding. A generalized linear model was used to assess the effect of experimental condition on the likelihood of providing responses within each of the identified categories. Participants exposed to the advertisements with (vs. without) warnings were more likely to provide responses related to NCDs or nutritional warnings. Meanwhile, no significant differences were found in the frequency of mention of categories related to sensory, hedonic, emotional, or social aspects linked to consuming the products between participants
exposed to advertisements with and without warnings. These results suggest that nutritional warnings may be a promising strategy to make consumers aware of the nutritional characteristics of ultra-processed products without affecting the ability of advertisements to convey their intended message.]]> Pérez, Lucía]]> Antúnez, Lucía]]> Otterbring, Tobias]]> Ares, Gastón]]>

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]]> Social representations of cooking and homemade meals]]> that the social representations of homemade meals were largely consensual among participants and mainly related to pleasure, health, and wellbeing. However, the social representations of cooking did not have a clear structure, which raised diverse associations related to homemade foods, positive emotions but also to lack of convenience in terms of time and effort. Results suggest public campaigns aimed at encouraging people to cook from scratch should position cooking as enjoyable task and diminish perception of lack of time and effort association.]]> Gugliucci, Vanessa]]> Vitola, Agustina]]> Girona, Alejandra]]> Santín, Viviana]]> Vidal, Leticia]]> Giménez, Ana]]> Curutchet, María Rosa]]> Ares, Gastón]]>

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]]> A peculiar cell cycle arrest at g2/m stage during the stationary phase of growth in the wine yeast Hanseniaspora vineae.]]> Schwarz, Luisa Vivian]]> Valera, María José]]> Longaray Delamare, Ana Paula]]> Carrau, Francisco]]> Echeverrigaray, Sergio]]> Información sobre Derechos de Autor

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]]> Structure-based boisosterism design, synthesis, biological evaluation and in silico studies of benzamide analogs as potential anthelmintics]]> NEMATODA]]> Vairoletti , Franco]]> Paulino, Margot]]> Mahler, Graciela]]> Salinas, Gustavo]]> Saiz, Cecilia]]> Información sobre Derechos de Autor

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]]> Adding sunflower or soybean oil to goat’s pasturebased diet improves the lipid profile without changing the sensory characteristics of milk]]> Dauber, Cecilia]]> Carreras, Tatiana]]> Casarotto Daniel, Gabriela]]> Cabrera, Fabiana]]> Liscano, Adriana]]> Vicente, Gabriela]]> Britos, Alejandro]]> Carro, Silvana]]> Cajarville, Cecilia]]> Gámbaro, Adriana]]> Vieitez, Ignacio]]>

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]]> New insights into the biophysical behavior of an old molecule: eperimental and theoretical studies of the interaction between 1,10-Phenanthroline and model phospholipid membranes]]> Alvarez, Natalia ]]> Freddi, Priscilla ]]> Castellani, Stephanie ]]> Veiga, Nicolás ]]> Facchin, Gianella ]]> Costa Filho, Antonio J. ]]> Información sobre Derechos de Autor

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]]> Tetramethyl-phenanthroline copper complexes in the development of drugs to treat cancer: synthesis, characterization and cytotoxicity studies of a series of copper(II)-L-dipeptide-3,4,7,8-tetramethyl-phenanthroline complexes]]> Alvarez, Natalia ]]> Leite, Celisnolia M. ]]> Napoleone, Adriana ]]> Mendes, Luis F. S. ]]> Fernández, Carlos Y. ]]> Ribeiro, Ronny R.]]> Ellena, Javier ]]> Batista, Alzir A.]]> Costa Filho, Antonio J. ]]> Facchin, Gianella ]]> Información sobre Derechos de Autor

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]]> Readily accessible azido-alkyne-functionalized monomers for the synthesis of cyclodextrin analogues using click chemistry]]> product distribution of the oligomerization could be modulated by the monomer concentration and the use of additives, generating mainly cyclic oligomers consisting of tetramers, pentamers and hexamers.]]> Daher, Grysette]]> Seoane, Gustavo]]>

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]]> Trapping of retrachydes thoracicus thoracicus (Olivier) and other neotropical Cerambycid beetles in pheromone- and kairomone-baited traps
]]> Amorós, María Eugenia]]> Lagarde, Lautaro ]]> Do Carmo, Hugo]]> Heguaburu, Vivivana ]]> Monné, Marcela ]]> Buenahora, José ]]> González, Andrés ]]> Información sobre Derechos de Autor

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]]> Application of near-infrared spectroscopy/artificial neural network to quantify glycosylated norisoprenoids in Tannat grapes]]> Boido, Eduardo]]> Fariña, Laura]]> Carrau, Francisco]]> Cozzolin, Daniel]]> Dellacassa, Eduardo]]>

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]]> A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes]]> Benítez, Diego]]> Dibello, Estefanía]]> Bonilla, Mariana]]> Comini, Marcelo A.]]>

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]]> Trends in the monitoring of legacy and emerging organic pollutants in protected areas]]> Azcune, Germán]]> Griffero, Luciana]]> Pareja Pereira, María Lucía]]> Ríos, Juan Manuel]]> Galbán Malagón, Cristobal]]> Pérez Parada, Andrés]]>

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]]>