<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/">
<rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3505">
    <dcterms:title><![CDATA[<strong>Antibody response of Echinococcus granulosus infected mice : recognition of glucidic and peptidic epitopes and lack of avidity maturation.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ECHINOCOCCUS GRANULOSUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTICUERPOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1996]]></dcterms:subject>
    <dcterms:abstract><![CDATA[. granulosus;secondary hydatidosis in mice;carbohydrate epitopes;antibody avidity The antibody response was followed weekly during 68 weeks in 17 Balb/c mice intraperitoneally (i.p.) infected with 2000 Echinococcus granulosus protoscoleces (PSC) and in three mice i.p. immunized with 2000 dead PSC. Antibodies against hydatid cyst fluid (HCFA) and its peptidic (periodate-resistant) and carbohydrate (periodate-sensitive) epitopes were titrated by ELISA. Avidity and the antigen recognition pattern of antibodies were also analysed during infection and immunization by ELISA and immunoblot, respectively. The antibody response of infected mice showed quantitative and qualitative variations during infection, since both titre as well as recognition of peptide and carbohydrate epitopes in HCFA depended on time post infection. No avidity maturation was evident during the course of infection. Sera from infected mice recognized the 38 kDa subunit of Ag5 but did not react with the 8 kDa subunit of AgB. On the contrary, the antibody response of immunized mice showed only one peak of antibodies that recognized both peptidic and carbohydrate epitopes of HCFA. In addition, sera from these mice recognized mainly 60 and 110 kDa bands. Our results suggest that: a) avidity and antigen recognition patterns of antibodies in mice treated with live PSC are different from those treated with dead PSC; b) antibodies against HCFA glucidic or peptidic epitopes appear at different times post infection.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Ferragut, Gabriela</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=9d36a9655c915bddd80b664491d73ec8"><strong>Nieto, Alberto</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Parasite Immunology v. 18, , 1996. -- p. 393-402]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley]]></dcterms:publisher>
    <dcterms:date><![CDATA[1997]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1046/j.1365-3024.1996.d01-125.x]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/1044">
    <dcterms:title><![CDATA[<strong>Anticholinesterasic, nematostatic and anthelmintic activities of pyridinic and pyrazinic compounds</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIHELMINTICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PRODUCTOS NATURALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2011]]></dcterms:subject>
    <dcterms:abstract><![CDATA[In the search for acetylcholinesterase inhibitors as a potential target for the discovery of anthelmintic drugs, a series of 27 pyridinic and pyrazinic compounds have been designed on the basis of molecular hybridization of two known AChE inhibitors, namely, tacrine and (-)-3-O-acetylspectaline, and on the concept of isosterism. The synthesized compounds generally presented moderate anticholinesterasic activities when compared with the positive control physostigmine, but one compound (ethyl 2-[(6-chloropyrazin-2-yl)sulfanyl] acetate, 11) exhibited an in vitro ability to immobilize the root-knot nematode Meloidogyne incognita that was highly comparable to that of the positive control Temik. Moreover, in anthelmintic assays against the gastrointestinal parasitic nematode Nippostrongy-lus brasiliensis (L4), some of the compounds, such as (6-chloropyrazin-2-yl)sulfanyl ethanol (32, EC50 = 33 nM), presented activities that were considerably stronger than that of the positive control albendazole (EC50 = 340 nM). In the light of the positive results obtained in the anthelmintic evaluations, the acute oral toxicity of the representative compound diethyl 2,2'-[(3-nitropyridine-2,6-diyl) bissulfanediyl] diacetate (7) was determined in rats, and the drug was shown to be non-toxic at a dose of 2000 mg/kg. These results, allied with the relatively simple structures of the active compounds and their facile synthesis, highlight their potential use as anthelmintic or nematicidic agents.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Valli, M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Danuello, A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Pivatto, M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Salda&ntilde;a, J. C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0f8b88f1a07d7ad1bd23900b47efb225" target="_blank"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dom&iacute;nguez, Laura</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Campos, V. P</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Marqui, S. R.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Young, M. C. M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Viegas, Jr. C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Silva, D. H. S.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bolzani, V. S.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Current Medicinal Chemistry v. 18, no. 22, 2011. -- p. 3423-3430]]></dcterms:source>
    <dcterms:publisher><![CDATA[Bentham Science Publishers]]></dcterms:publisher>
    <dcterms:date><![CDATA[2011]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISSN: 0929-8673 (Print)]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/621">
    <dcterms:title><![CDATA[<strong>Anticonvulsant, neuroprotective and behavioral effects of organic and conventional yerba mate (Ilex paraguariensis St. Hil.) on pentylenetetrazol-induced seizures in Wistar rats</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTICONVULSIVOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[YERBA MATE]]></dcterms:subject>
    <dcterms:subject><![CDATA[ILEX PARAGURIENSIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2013]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Epilepsy, which is one of the most common neurological disorders, involves the occurrence of spontaneous and recurrent seizures that alter the performance of the brain and affect several sensory and behavioral functions. Oxidative damage has been associated with post-seizure neuronal injury, thereby increasing an individual&rsquo;s susceptibility to the occurrence of neurodegenerative disorders. The present study investigated the possible anticonvulsive and neuroprotective effects of organic and conventional yerba mate (Ilex paraguariensis), a plant rich in polyphenols, on pentylenetetrazol (PTZ)-induced seizures in Wistar rats. The behavioral and polyphenolic profiles of the yerba mate samples were also evaluated. Infusions of yerba mate (50 mg/kg) or distilled water were given to rats for fifteen days by oral gavage. On the 15th day the animals were subjected to open field test, and exploratory behavior was assessed. Subsequently, 60 mg/kg PTZ (i.p.) was administered, and animals were observed for the appearance of convulsions for 30 min. Latency for the first seizure, tonic&ndash;clonic and generalized seizures time, frequency of seizures and mortality induced by PTZ were recorded. The animals were then sacrificed, and the cerebellum, cerebral cortex and hippocampus were quickly removed and frozen to study the neuroprotective effects of yerba mate. The oxidative damage in lipids and proteins, nitric oxide levels, the activities of the antioxidant enzymes superoxide dismutase (Sod) and catalase (Cat) and non-enzymatic cellular defense (sulfhydryl protein) were quantified in all the tissues. The results showed that organic and conventional yerba mate infusions were able to reduce the frequency of seizures when compared to the PTZ group. Besides, organic yerba mate infusion decreases the tonic&ndash;clonic seizures time in relation to the PTZ group. It was also shown that organic and conventional yerba mate infusions reduced the oxidative damage in lipids and proteins and nitric oxide levels and prevented the decrease in Sod and Cat activities and sulfhydryl protein content when compared to the PTZ group in all the CNS tissues assayed. Organic and conventional yerba mate commercial samples did not change the behavior (locomotion, exploration or anxiety) of the treated animals. In both organic and conventional infusions, the presence of the polyphenols rutin, chlorogenic acid and their acyl derivatives were detected, which could be associated with the biological effects observed. These data indicate that yerba mate may provide new perspectives for the development of therapeutic approaches with natural compounds in the pharmaceutical area, both to reduce the convulsions&rsquo; frequency and to minimize the neuronal damage associated with recurrent seizures.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>dos Santos Branco, C&aacute;tia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Scola, Gustavo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dalpicolli Rodrigues, Adriana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0a105db2a5a7c020d6e14e25180d1b21" target="_blank"><strong>Cesio, Ver&oacute;nica</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Laprovitera, Mariajos&eacute;</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0f8b88f1a07d7ad1bd23900b47efb225" target="_blank"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Telles dos Santos, Mait&eacute;</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Frank, Bruna</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cesa Vieira de Freitas, Suzana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Simon Coitinho, Adriana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Salvador, Mirian</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Brain Research Bulletin v. 92, 2013. -- p. 60-68]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2013]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[http://dx.doi.org/10.1016/j.brainresbull.2012.11.008]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5052">
    <dcterms:title><![CDATA[<strong>Anticonvulsivantes : dosificaci&oacute;n en plasma sangu&iacute;neo</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[<strong>ANTICONVULSIVANTS</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>ANTIEPILEPTICOS</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>FARMACOLOGIA</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>CROMATOGRAFIA DE GASES</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>ENZIMA INMUNOENSAYO</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>ANTICONVULSIVOS</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>PLASMA SANGUINEO</strong>]]></dcterms:subject>
    <dcterms:publisher><![CDATA[Biblioteca-FQ]]></dcterms:publisher>
    <dcterms:date><![CDATA[1981]]></dcterms:date>
    <dcterms:format><![CDATA[Papel]]></dcterms:format>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[<strong>Ingl&eacute;s</strong>]]></dcterms:language>
    <dcterms:language><![CDATA[<strong>Espa&ntilde;ol</strong>]]></dcterms:language>
    <dcterms:type><![CDATA[Bibliograf&iacute;a]]></dcterms:type>
    <dcterms:temporal><![CDATA[1972-1981]]></dcterms:temporal>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5173">
    <dcterms:title><![CDATA[<strong>Antiepil&eacute;pticos, anticonvulsivantes : determinaci&oacute;n por TLC o GLC</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[<strong>ANTIEPILEPTICOS</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>ANTICONVULSIVOS</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>QUIMICA ANALITICA</strong>]]></dcterms:subject>
    <dcterms:subject><![CDATA[<strong>CROMATOGRAFIA</strong>]]></dcterms:subject>
    <dcterms:publisher><![CDATA[Biblioteca-FQ]]></dcterms:publisher>
    <dcterms:date><![CDATA[1984]]></dcterms:date>
    <dcterms:format><![CDATA[Papel]]></dcterms:format>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Bibliograf&iacute;a]]></dcterms:type>
    <dcterms:temporal><![CDATA[1980-1982]]></dcterms:temporal>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/2202">
    <dcterms:title><![CDATA[<strong>Antiepileptic drugs :&nbsp; Energy-consuming processes governing drug disposition</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIEPILETICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PRODUCTOS FARMACEUTICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2014]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Diffusion is not the main process by which drugs are disposed throughout the body. Translational movements of solutes given by different energy-consuming mechanisms are required in order to dispose them efficiently. Membrane transportation and cardiac output distribution are two effective processes to move the molecules among different body sites. Gastrointestinal-blood cycling constitutes a supplementary way to regulate the distribution of molecules between the non-hepatic organs and the liver. Any change in the relative supply of drug molecules among eliminating organs could modify their clearance from the body. Either the nonlinear phenytoin (PHT) pharmacokinetic response or the influence that carbamazepine (CBZ) exerts on PHT exposure could be explained throughout their efflux transporter inducer abilities. Cardiac output distribution difference between the individuals might also explain the dual CBZ-over-PHT interaction response. Finally, valproic acid (VPA) pharmacokinetics can be understood by adding to these mechanisms of transportation its ability to cross the mitochondrial membrane of the hepatocyte.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=caabbc98478c9c9fb71e4b0eb4e4ccd5" target="_blank"><strong>Fagiolino, Pietro</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>V&aacute;zquez, Marta</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Alvariza, Silvana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Maldonado, Cecilia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ibarra, Manuel</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Olano, Ivette</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Frontiers in bioscience (Elite edition)&nbsp; v. 6, 2014. -- p. 6687-96]]></dcterms:source>
    <dcterms:publisher><![CDATA[Frontiers in Bioscience]]></dcterms:publisher>
    <dcterms:date><![CDATA[2014]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISSN: 1945-0494 (Print)]]></dcterms:identifier>
    <dcterms:identifier><![CDATA[ISSN: 1945-0508 (Electronic)]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4549">
    <dcterms:title><![CDATA[<strong>Antif&uacute;gos de la flora nativa uruguaya</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIF&Uacute;NGICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[MONTE NATIVO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BOT&Aacute;NICA FARMAC&Eacute;UTICA]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Los hongos potencialmente pat&oacute;genos para el ser humano constituyen un peque&ntilde;o grupo de pocos centenares entre los cientos de miles de especies del Reino Fungi. Son capaces de producir infecciones denominadas micosis, aunque en menor grado se dan tambi&eacute;n procesos al&eacute;rgicos o intoxicaciones por ingesti&oacute;n. Los principales hongos pat&oacute;genos est&aacute;n distribuidos en casi la totalidad de los phyla de su Reino, diversificando estrategias de patogenicidad y virulencia (James 2006). A este factor se agrega el gran n&uacute;mero de individuos en las poblaciones microbianas, con ciclos de vida cortos comparados con otros eucariotas y de r&aacute;pida evoluci&oacute;n (Heitman 2011), adaptables a condiciones ambientales adversas o diferentes hu&eacute;spedes]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Bertucci, Ana</strong>]]></dcterms:creator>
    <dcterms:publisher><![CDATA[Montevideo: UdelaR-Facultad de Qu&iacute;mica]]></dcterms:publisher>
    <dcterms:date><![CDATA[2013]]></dcterms:date>
    <dcterms:contributor><![CDATA[<strong>Dr. Gonz&aacute;lez Berrutti, David (director de Tesis)</strong>]]></dcterms:contributor>
    <dcterms:contributor><![CDATA[<strong>Dr. Moyna, Patrick.(director de Tesis)</strong>]]></dcterms:contributor>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor </strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[Papel]]></dcterms:format>
    <dcterms:language><![CDATA[Espa&ntilde;ol]]></dcterms:language>
    <dcterms:type><![CDATA[Tesis]]></dcterms:type>
    <dcterms:identifier><![CDATA[58 BER]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4374">
    <dcterms:title><![CDATA[<strong>Antif&uacute;ngicos : derivados azufrados, disulfuro de tetrametiltiacarbamil</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIFUNGICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1960]]></dcterms:subject>
    <dcterms:creator><![CDATA[<strong>Menes, J. E.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Bolet&iacute;n de la Sociedad Uruguaya de Farmacia y Bioqu&iacute;mica Industriales n&ordm;. 4, 1960. -- p. 9-17]]></dcterms:source>
    <dcterms:publisher><![CDATA[Sociedad Uruguaya de Farmacia y Bioqu&iacute;mica Industriales]]></dcterms:publisher>
    <dcterms:date><![CDATA[1960]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /> <br /> (Por favor lea este aviso antes de abrir los documentos u objetos)<br /> <br /> <strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /> <br /> (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /> <br /> <strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Espa&ntilde;ol]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4373">
    <dcterms:title><![CDATA[<strong>Antif&uacute;ngidos : antibi&oacute;ticos</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIFUNGICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIBIOTICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[1960]]></dcterms:subject>
    <dcterms:creator><![CDATA[<strong>Menes, J. E.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Bolet&iacute;n de la Sociedad Uruguaya de Farmacia y Bioqu&iacute;mica Industriales n&ordm;. 6, 1960. -- p. 6-8]]></dcterms:source>
    <dcterms:publisher><![CDATA[Sociedad Uruguaya de Farmacia y Bioqu&iacute;mica Industriales]]></dcterms:publisher>
    <dcterms:date><![CDATA[1960]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /> <br /> (Por favor lea este aviso antes de abrir los documentos u objetos)<br /> <br /> <strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /> <br /> (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /> <br /> <strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Espa&ntilde;ol]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3244">
    <dcterms:title><![CDATA[<strong>Antifeedant activity and effects of fruits and seeds extracts of Cabralea canjerana canjerana (Vell.) Mart. (Meliaceae) on the immature stages of the fall armyworm Spodoptera frugiperda (JE Smith) (Lepidoptera: Noctuidae)</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PRODUCTOS NATURALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ALIMENTOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[CABRALEA CANJERANA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ACTIVIDAD OVICIDA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ACTIVIDAD LARVICIDA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2015]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The biological activity of ethyl acetate and ethanolic fruit and seed extracts from Cabralea canjerana oneggs, larvae and pupae of the fall armyworm (FAW) (Spodoptera frugiperda) was evaluated. Silica gelcolumn chromatography fractionation of the most active extract, the ethyl acetate seed one, yielded fivefractions whose bioactivity was also evaluated. All extracts showed high larvicidal and antifeedant activityat the highest evaluated concentration. They also altered significantly the life cycle of the FAW, the larvalweight, and induced various larval and pupal abnormalities. The most active fraction, mainly composed oftriterpenes, at 165 mg/kg, killed 60% of the larvae. The main component from this fraction was isolated andcharacterized, resulting in a new dammarane triterpene, ocotillone 7,15 diol. The extracts and fractionsas a whole, showed higher activity compared to toxicity values from the isolated compounds from C.canjerana to FAW reported in the literature. Moreover, as C. canjerana is distributed throughout theAmericas and its extracts showed a promising biological activity with Category III toxicity level, accordingto the OECD 425 assay, they could be used as a potential natural pesticide.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Magrini, Flaviane Eva</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Specht, Alexandre</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gaio, Juliano</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Girelli, Cristiane Priscila</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Migues, Ignacio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0f8b88f1a07d7ad1bd23900b47efb225" target="_blank"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=1adf3c6818ae9c0ff60309b22359778f" target="_blank"><strong>Salda&ntilde;a, Jenny</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Sartori, Valdirene C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0a105db2a5a7c020d6e14e25180d1b21" target="_blank"><strong>Cesio, Mar&iacute;a Veronica</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Industrial Crops and Products v. 65, 2015. -- p. 150-158]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2015]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
<p><br /><br /></p>
<p style="margin-bottom: 0cm;">&nbsp;</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[http://dx.doi.org/10.1016/j.indcrop.2014.11.032]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3817">
    <dcterms:title><![CDATA[<strong>Antifeedant and repellent effects of neotropical Solanum extracts on drywood termites (Cryptotermes brevis, Isoptera: Kalotermitidae)</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[REPELENTES]]></dcterms:subject>
    <dcterms:subject><![CDATA[PRODUCTOS NATURALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[SOLANUM BISTELLATUM]]></dcterms:subject>
    <dcterms:subject><![CDATA[SOLANUM SISYMBRIFOLIUM]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2015]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Antifeedant and repellent effects of two different extracts from native Solanum species Solanum bistellatum and Solanum sisymbrifolium on Cryptotermes brevis were evaluated. The extracts obtained, particularly the dichloromethane extracts and the enriched fraction of sugar esters from S. sisymbrifolium and S. bistellaltum, showed antifeedant and repellent action against the termite. The antifeedant effect of dichloromethane extract from S. sisymbrifolium at the concentration of 25.00mg/mL reached 100%, while the repellent action of the dichloromethane extracts and that of the enriched fraction of sugar esters at the concentration of 1.00mg/mL was higher than 90%. In case of S. bistellatum, the antifeedant effect of the dichloromethane extract and the enriched fraction of sugar esters at the concentration of 25.00mg/mL was 43.29% and 57.46%, respectively. The repellent action of the dichloromethane extracts and of the enriched fraction of sugar esters at a concentration level of 2.50mg/mL was higher than 92%.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Rech Cainelli, V.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Barros, N. M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Giani, S. G.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Sbeghen-Loss, A. C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0f8b88f1a07d7ad1bd23900b47efb225" target="_blank"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Miguez, I.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Specht, A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0a105db2a5a7c020d6e14e25180d1b21" target="_blank"><strong>Cesio, Mar&iacute;a Veronica</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Sociobiology v. 62, no. 1, 2015. -- p. 82-87]]></dcterms:source>
    <dcterms:publisher><![CDATA[Universidade Estadual de Feira de Santana]]></dcterms:publisher>
    <dcterms:date><![CDATA[2015]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /> <br /> (Por favor lea este aviso antes de abrir los documentos u objetos)<br /> <br /> <strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /> <br /> (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /> <br /> <strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.13102/sociobiology.v62i1.82-87]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/2108">
    <dcterms:title><![CDATA[<strong>Antifungal Activity of a Library of Cyclitols and Related Compounds</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIFUNGICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[AMINOACIDOS CONJUGADOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2014]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The antifungal activity of a library of 32 cyclitols and derivatives, including 6 previously unreported cyclitol amino acid conjugates, was studied against the clinically important yeasts Candida albicans, Candida tropicalis and Cryptococcus neoformans along with Saccharomyces cerevisiae. Bioautography followed by standardized microbroth dilution methods were used and allowed to identify an azidoinositol glycoside (11) and an azidoconduritol linked to an aromatic aldehyde (18) as promising compounds. The results suggest the relevance of exploring synthetic cyclitolic structures as potential antifungal leaders.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Bellomo, Ana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=c4cd2799a898a5e0e127ab223fa32d80" target="_blank"><strong>Bertucci, Ana</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>de la Sovera, Victoria</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Carrau, Gonzalo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Raimondi, M&oacute;nica</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Zacchino, Susana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Stefani, Helio A.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=300838f98061f526032e39f0b9df862d" target="_blank"><strong>Gonz&aacute;lez, David</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Letters in Drug Design &amp; Discovery&nbsp; v. 11, 2014. -- p. 67-75]]></dcterms:source>
    <dcterms:publisher><![CDATA[Bentham Science Publishers]]></dcterms:publisher>
    <dcterms:date><![CDATA[2014]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISSN: 1875-628X (Online)]]></dcterms:identifier>
    <dcterms:identifier><![CDATA[ISSN: 1570-1808 (Print)]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/781">
    <dcterms:title><![CDATA[<strong>Antifungal activity of medicinal plant extracts against phytopathogenic fungus Alternaria SPP.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PLANTAS MEDICINALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIFUNGICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[URUGUAY]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2011]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The aim of the study was to evaluate the antifungal activity of extracts of 10 plant species used in traditional Uruguayan medicine against the phytopathogenic fungus Alternaria spp. The plants were selected on the basis of their reported ethnobotanical uses. Aqueous, saline buffer and acid extracts of different plant species were screened in vitro for their antifungal activity against Alternaria spp. For the antifungal evaluation we used a microspectrophotometric assay. Minimal inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of the extracts were determined. Three solvents were assayed on different tissues of the plants and among the 29 evaluated extracts, 31% of the extracts inhibited growth, similar to the effects of a chemical fungicide. Acid extracts of the plants were more effective than the aqueous or buffer extracts against Alternaria spp. The MIC values of the extracts were determined ranging between 1.25 and 25 &mu;g mL-1. The MFC values of the extracts ranged between 1.25 &mu;g mL-1 (Rosmarinus officinalis L.) and 10 &mu;g mL-1 (Cynara scolymus L.). MICs and MFCs values obtained from leaves (Salvia officinalis L. and R. officinalis) and seeds extracts (Salvia sclarea L.) were quite comparable to values obtained with the conventional fungicide captan (2.5 &mu;g mL-1). The extracts of Salvia sclarea, S. officinalis and R. officinalis could be considered as potential sources of antifungal compounds for treating diseases in plants. These extracts showed maximum activity, even at very low concentrations, and the same fungicide effects as chemical fungicide. We conclude from this that these extracts exhibit amazing fungicidal properties that support their traditional use as antiseptics]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>D&iacute;az Dellavalle, Paola Alexandra</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cabrera, Andrea</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Alem, Diego</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Larra&ntilde;aga, Patricia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=06ea8350d5f6e14cde5d4fa22f5ff626" target="_blank"><strong>Ferreira Chiesa, Fernando</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dalla Rizza, Marco</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chilean Journal of Agricultural Research v. 71, no. 2, 2011. -- p. 2231-239]]></dcterms:source>
    <dcterms:publisher><![CDATA[INIA]]></dcterms:publisher>
    <dcterms:date><![CDATA[2011]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISSN : 0718-5820 Print]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5650">
    <dcterms:title><![CDATA[<strong>Antigen B from Echinococcus granulosus is a novel ligand for C-reactive protein</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PROTEINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[PROTEINA C REACTIVA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ECHINOCOCCUS GRANULOSUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[MACROFAGOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2018]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Antigen B (EgAgB) is a phosphatidylcholine (PC)-rich lipoprotein of Echinococcus granulosus s.l. larva, potentially capable of modulating the activation of various myeloid cells, including macrophages. As C-reactive protein (CRP) can act as an innate receptor with ability to bind the phosphocholine moiety of PC in lipoproteins, we investigated whether EgAgB and CRP could interact during cystic echinococcosis infection (CE), and how CRP binding could affect the modulation activities exerted by EgAgB on macrophages. To that end, we firstly investigated the occurrence of CRP induction during human CE. We found that 61% of CE patients, but none of healthy donors, exhibited serum CRP levels higher than 10 mg/mL, suggesting that CRP can be induced during the chronic phase of CE. Furthermore, human CRP was capable of binding specifically to EgAgB with high affinity (0.6 &plusmn; 0.1 nM); this binding was Ca2+ -dependent and involved the phosphocholine moiety of PC, but not EgAgB8/1, EgAgB8/2 or EgAgB8/3 apolipoproteins. Finally, CRP presence altered the modulation exerted by EgAgB on the cytokine response of LPS-activated macrophages. Overall, our results suggest that CRP presence during CE may contribute to a complex scenario of interactions between EgAgB and myeloid cells, influencing the cytokine response induced during macrophage activation.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Silva-Alvarez, Valeria</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ramos, Anal&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Folle, Ana Maite</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lagos, Sof&iacute;a.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dee, Valerie M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Ferreira, Ana M.</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Parasite Immunology&nbsp; v. 40, no. 9, 2018. -- 6p.--e12575]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley]]></dcterms:publisher>
    <dcterms:date><![CDATA[2018]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1111/pim.12575]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/2184">
    <dcterms:title><![CDATA[<strong>Antileishmanial activity of furoquinolines and coumarins from Helietta apiculata.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PRODUCTOS NATURALES]]></dcterms:subject>
    <dcterms:subject><![CDATA[LEISHMANIASIS]]></dcterms:subject>
    <dcterms:subject><![CDATA[RUTACEAE]]></dcterms:subject>
    <dcterms:subject><![CDATA[CUMARINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2010]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The barkinfusionof H. apiculata are usedtotreatwoundhealingrelatedtocutaneousleishmaniasisand as anti-inflammatory. Aim ofthestudy: Toisolate,purifyactiveconstituentsof H. apiculata stem bark,andevaluatetheir in vitro and in vivo antileishmanialactivities. Materialsandmethods: Isolationbychromatographicmethodsandchemicalidentificationof furoquinolinealkaloidsandcoumarins,thenevaluationofthe in vitro leishmanicidalactivityofthese compoundsagainstthreestrainsof Leishmania sp. promastigotesand in vivo against Leishmania amazonensis in Balb/cmice. Results: Furoquinolinealkaloidsandcoumarinspresentedamoderate in vitro activity against promastigoteformsof Leishmania sp. withIC50 valuesintherangebetween17and 450 mg/ml. Balb/ c miceinfectedwith Leishmaniaamazonensis weretreatedwith g-fagarinebyoralroute,orwith3-(1&rsquo;- dimethylallyl)-decursinolor(-)-heliettinbysubscutaneousroutefor14daysat10mg/kgdaily.Inthese conditions, g-fagarine,3-(1&rsquo;-dimethylallyl)-decursinoland(-)-heliettinshowedthesameefficacyasthe reference drugreducingby97.4,95.6and98.6%theparasiteloadsinthelesion,respectively. Conclusion: Thesecompoundsshowedsignificantefficacyin L. amazonensis infectedmice,providing importantknowledgetoimproveitspotentialroleforafutureuseinthetreatmentofcutaneous leishmaniasis.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Ferreira, Mar&iacute;a Elena</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Rojas de Arias, Antonieta</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Yaluff, Gloria</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>de Bilbao, Ninfa Vera</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Nakayama, H&eacute;ctor</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Torres, Susana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Schinini, Alicia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Guy, Isabelle</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0f8b88f1a07d7ad1bd23900b47efb225"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fournet, Alain</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Phytomedicine v. 17, no. 5, 2010. -- p. 375-378]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2010]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[doi:10.1016/j.phymed.2009.09.009]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/1676">
    <dcterms:title><![CDATA[<strong>Antimicrobial activity of Xanthium cavanilesii extracts</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[MICROBIOLOGIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ABROJO]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIINFECCIOSOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[XANTHIUM CAVANILESII]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2007]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Development of new antimicrobial compounds against different microorganisms is becoming critically important, as infectious diseases are still one of the leading causes of death in the world. The pharmaceutical industry is searching for new lead compounds with novel chemical structures to overcome the increasing resistance to known antibiotics. Plants can be a useful source of these lead compounds. Xanthium cavanillesii Schouw (Asteraceae) grows wild in Uruguay, and its infusion is used in popular medicine as skin antiseptic. In this work, we present the study of the antimicrobial activity of several extracts of X. cavanillesii against different microorganisms. In the agar diffusion assays, the plant extracts showed an interesting antimicrobial activity, including activity against Mycobacterium smegmatis and Candida albicans. The extracts showed low toxicity in the acute oral assay performed with no deaths at a 200 mg=kg dose.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=52e013818d1066562588b928cb60fb7d" target="_blank"><strong>Cerdeiras, Mar&iacute;a P&iacute;a</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Albor&eacute;s, S.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Etcheverry, Silvia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Luci&aacute;n, V.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=250c85d1dca64d55cea187f29d9c4472" target="_blank"><strong>Soubes, Matilde</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://www.ccdt.udelar.edu.uy/wp-content/themes/corpo/adjuntos/604_curriculumvitae__curriculumvitaearchivo.pdf" target="_blank"><strong>V&aacute;zquez, Alvaro</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Pharmaceutical Biology v.45, no. 3., 2007. -- p. 251-254]]></dcterms:source>
    <dcterms:publisher><![CDATA[Taylor, Francis Online]]></dcterms:publisher>
    <dcterms:date><![CDATA[2007]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingles]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1080/13880200701214839]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5345">
    <dcterms:title><![CDATA[<strong>Antimicrobial and structural insights of a new snakin-like peptide isolated from Peltophorum dubium (Fabaceae)</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[PEPTIDOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ESCHERICHIA COLI]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANALISIS ANTIMICROMIBIANO]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2018]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Snakins are antimicrobial peptides (AMPs) found, so far, exclusively in plants, and known to be important in the defense against a wide range of pathogens. Like other plant AMPs, they contain several positively charged amino acids, and an even number of cysteine residues forming disulfide bridges which are considered important for their usual function. Despite its importance, studies on snakin tertiary structure and mode of action are still scarce. In this study, a new snakin-like gene was isolated from the native plant Peltophorum dubium, and its expression was verified in seedlings and adult leaves. The deduced peptide (PdSN1) shows 84% sequence identity with potato snakin-1 mature peptide, with the 12 cysteines characteristic from this peptide family at the GASA domain. The mature PdSN1 coding sequence was successfully expressed in Escherichia coli. The purified recombinant peptide inhibits the growth of important plant and human pathogens, like the economically relevant potato pathogen Streptomyces scabies and the opportunistic fungi Candida albicans and Aspergillus niger. Finally, homology and ab initio modeling techniques coupled to extensive molecular dynamics simulations were used to gain insight on the 3D structure of PdSN1, which exhibited a helix&ndash;turn&ndash;helix motif conserved in both native and recombinant peptides. We found this motif to be strongly coded in the sequence of PdSN1, as it is stable under different patterns of disulfide bonds connectivity, and even when the 12 cysteines are considered in their reduced form, explaining the previous experimental evidences.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Rodr&iacute;guez Decuadro, Susana Beatriz.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Barraco Vega, Mariano</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dans, Pablo D.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Pandolfi, Valesca</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Benko Issepon, Ana Mar&iacute;a</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=d2ef845d446577be6a2f257ee56582fa" target="_self"><strong>Cecchetto, Gianna</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Amino Acids v.50, 2018. -- p. 1245-1259]]></dcterms:source>
    <dcterms:publisher><![CDATA[Springer]]></dcterms:publisher>
    <dcterms:date><![CDATA[2018]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1007/s00726-018-2598-3]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4174">
    <dcterms:title><![CDATA[<strong>Antimicrobial evaluation of new metallic complexes with xylitol active against P. aeruginosa and C. albicans :&nbsp; MIC determination, post-agent effect and Zn-uptake</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[MICROBIOLOGIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[XYLITOL]]></dcterms:subject>
    <dcterms:subject><![CDATA[COBRE]]></dcterms:subject>
    <dcterms:subject><![CDATA[ZINC]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2016]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Xylitol (xylH5) is metabolized via the pentose pathway in humans, but it is unsuitable as an energy source for many microorganisms where it produces a xylitol-induced growth inhibition and disturbance in protein synthesis. For this reason, xylitol is used in the prophylaxis of several infections. In the search of better antimicrobial agents, new copper and zinc complexes with xylitol were synthesized and characterized by analytical and spectroscopic methods: Na2[Cu3(xylH&minus;4)2]&middot;NaCl&middot;4.5H2O (Cu-xyl) and [Zn4(xylH&minus;4)2(H2O)2]&middot;NaCl&middot;3H2O (Zn-xyl). Both copper and zinc complexes presented higher MIC against Pseudomona aeruginosa than the free xylitol while two different behaviorswere found against Candida albicans depending on the complex. The growth curves showed that Cu-xyl presented lower activity than the free ligand during all the studied period. In the case of Znxyl the growth curves showed that the inhibition of the microorganism growth in the first stage was equivalent to that of xylitol but in the second stage (after 18 h) Zn-xyl inhibited more. Besides, the PAE (post agent effect) obtained for Zn-xyl and xyl showed that the recovery from the damage of microbial cells had a delay of 14 and 13 h respectively. This behavior could be useful in prophylaxis treatments for infectious diseases where it is important that the antimicrobial effect lasts longer. With the aim to understand themicrobiological activities the analysis of the particle size, lipophilicity and Zn uptake was performed.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Santi, Eduardo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=5df591c19cc13f11564074d135cd4838" target="_blank"><strong>Facchin, Gianella</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=fc7cd71892b1a9968ee19230dafdbd01" target="_blank"><strong>Faccio, Ricardo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Barroso, R. P.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Costa Filho, A.J</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Borthagaray, Graciela</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=1be7431d37af92df16867e8519adf042" target="_blank"><strong>Torre, Mar&iacute;a H.</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Inorganic Biochemistry v. 155, 2016. -- p. 67-75]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2016]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
<p><br /><br /></p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[http://dx.doi.org/10.1016/j.jinorgbio.2015.11.014]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4485">
    <dcterms:title><![CDATA[<strong>Antimutagenic and antioxidant properties of the aqueous extracts of organic and conventional grapevine Vitis labrusca cv. Isabella leaves in V79 cells</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[UVAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[ACTIVIDAD ANTIGENOTOXICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ACTIVIDAD ANTIMUTAGENICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[VITIS LABRUSCA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2016]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Grapes are one of the most commonly consumed fruit, in both fresh and processed forms; however, a significant amount is disposed of in the environment. Searching for a use of this waste, the antigenotoxic, antimutagenic, and antioxidant activities of aqueous extracts from organic and conventional Vitis labrusca leaves were determined using V79 cells as model. The antigenotoxic activity was analyzed by the alkaline comet assay using endonuclease III and formamidopyrimidine DNA glycosylase enzymes. The antimutagenic property was assessed through the micronucleus (MN) formation, and antioxidant activities were assessed using 2',7'-dichlorodihydrofluorescin diacetate (DCFH-DA) assay and 2,2-diphenyl-1-picrylhydrazyl (DPPH(●)) radical scavenging, as well as with superoxide dismutase (SOD) and catalase (CAT) activity assays. In addition, phenolic content and ascorbic acid levels of both extracts were determined. Data showed that both organic and conventional grapevine leaves extracts possessed antigenotoxic and antimutagenic properties. The extract of organic leaves significantly reduced intracellular reactive oxygen species (ROS) levels in V79 cells, and displayed greater ability for DPPH(●) scavenging and higher SOD and CAT activities than extract from conventional leaves. Further, the extract from organic leaves contained higher phenolic and ascorbic acid concentrations. In summary, extracts from organic and conventional grape leaves induced important in vitro biological effects.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Trindade, Cristiano</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Vera Bortolini, Giovana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Segalotto Costa, B&aacute;rbara</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Carra Anghinoni, Joanna</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Nikolova Guecheva, Temenouga</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Arias, Ximena</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0a105db2a5a7c020d6e14e25180d1b21" target="_blank"><strong>Cesio, Mar&iacute;a Ver&oacute;nica</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0f8b88f1a07d7ad1bd23900b47efb225" target="_blank"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Moura, Dinara Jacqueline</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Saffi, Jenifer</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Salvador, Mirian</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>P&ecirc;gas Henriques, Jo&atilde;o Antonio</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Toxicology and Environmental Health part. A&nbsp; v. 79, no. 18, 2016. -- p. 825-836]]></dcterms:source>
    <dcterms:publisher><![CDATA[Taylor &amp; Francis]]></dcterms:publisher>
    <dcterms:date><![CDATA[2016]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI: 10.1080/15287394.2016.1190675]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5238">
    <dcterms:title><![CDATA[<strong>Antioxidant activity of a Oryzanols concentrate by differential scannning calorimetry</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ACEITES]]></dcterms:subject>
    <dcterms:subject><![CDATA[OXIDACION]]></dcterms:subject>
    <dcterms:subject><![CDATA[CALORIMETRIA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2018]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Oryzanols are natural antioxidants that are found in appreciable amounts in rice bran oil. However, by chemically refining the crude rice bran oil they are lost during the chemical neutralization step leaving the oil refined with very little oryzanols. The chemical neutralization leaves a residue called "soapstocks" where most of these antioxidants are found. From the soapstocks and by relatively simple procedures it is possible to obtain a oryzanols concentrate which may contain 33% of them. However, its antioxidant power has been little studied in oils compared to other natural antioxidants. Therefore, the present work gives information about the antioxidant power of a concentrate of oryzanols compared to natural antioxidants such as tocopherol and synthetic antioxidants such as butylhydroxytoluene (BHT) added in oils with different degrees of unsaturation and without antioxidants. The results determined by the differential scanning calorimetry method show that the antioxidant power was variable according to the method used. The tocopherol protected the oils from the oxidation at 130&deg;C (soybean and high oleic sunflower) better than the oryzanols concentrate by the isothermal method. When the non-isothermal method was used it was found that the-tocopherol protected soybean oil better than oleic high sunflower oil compared to the oryzanols concentrate. However, when comparing BHT with oryzanols concentrate, BHT generally had a lower protection in both oils and both methods. These results show that the oryzanols concentrate has a protective effect of the oxidation of the studied oils, however, this could depend on the degree of the oil unsaturation.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curiculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=4893deebda650ee6c099fb08fe5c40e3" target="_blank"><strong>Irigaray, Bruno</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curiculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=178a48bba0993fb17ba1ac64b40d019c" target="_blank"><strong>Jachmanian, Ivan</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=6586904caf76687142b8c1917494e201" target="_blank"><strong>Grompone, Mar&iacute;a Antonia</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Food Research v. 7, no. 1, 2018. -- p. 38-45]]></dcterms:source>
    <dcterms:publisher><![CDATA[The Canadian Center of Science and Education]]></dcterms:publisher>
    <dcterms:date><![CDATA[2018]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.5539/jfr.v7n1p38]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/992">
    <dcterms:title><![CDATA[<strong>Antioxidant Activity of Uruguayan Propolis : In Vitro and Cellular Assays</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIOXIDANTES]]></dcterms:subject>
    <dcterms:subject><![CDATA[PROPOLEOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2011]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The antioxidant capacity of propolis from the southern region of Uruguay was evaluated using in vitro as well as cellular assays. Free radical scavenging capacity was assessed by ORAC, obtaining values significantly higher than those of other natural products (8000 &mu;mol Trolox equiv/g propolis). ORAC values correlated well with total polyphenol content (determined by FolinCiocalteu method) and UV absorption. Total polyphenol content (150 mg gallic acid equiv/g propolis) and flavonoids (45 mg quercetin equiv/g propolis) were similar to values reported for southern Brazilian (group 3) and Argentinean propolis. Flavonoid composition determined by RP-HPLC indicates a strong poplar-tree origin. Samples high in polyphenols efficiently inhibit low-density lipoprotein lipoperoxidation and tyrosine nitration. In addition, Uruguayan propolis was found to induce the expression of endothelial nitric oxide synthase and inhibit endothelial NADPHoxidase, suggesting a potential cardiovascular benefit by increasing nitric oxide bioavailability in the endothelium.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Silva, Ver&oacute;nica</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Genta, Gonzalo</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>M&ouml;ller, Mat&iacute;as Nicol&aacute;s</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Masner, Mart&iacute;n</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Thomson, Leonor</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Romero, Natalia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Radi, Rafael</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fernandes, Denise C.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Laurindo, Francisco R. M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0f8b88f1a07d7ad1bd23900b47efb225" target="_blank"><strong>Heinzen, Horacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fierro, Walter</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Denicola Creci, Ana Beatriz</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Agricultural and Food Chemistry v. 59, no. 12, 2011. -- p. 6430-6437]]></dcterms:source>
    <dcterms:publisher><![CDATA[American Chemical Society]]></dcterms:publisher>
    <dcterms:date><![CDATA[2011]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[dx.doi.org/10.1021/jf201032y]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/5299">
    <dcterms:title><![CDATA[<strong>Antioxidant and antibacterial activity of different extracts from herbs obtained by maceration or supercritical technology</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIOXIDANTES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ ACTIVIDAD ANTIBACTERIANA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ EXTRACTOS DE HIERBAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[EXTRACCION SUPERCRITICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2018]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Supercritical fluid extraction with carbon dioxide has been demonstrated to be an attractive method to apply to different processes involved in the food industry due to several advantages when it is compared with conventional organic solvents. Supercritical CO2 extracts from rosemary (Rosmarinus officinalis), boldo (Peumus boldus), cedron (Aloysia citrodora), congorosa (Maytenus ilicifolia), yerba mate (Ilex paraguariensis) and pitanga (Eugenia uniflora) were obtained at different extraction conditions; their antioxidant effect was studied and compared with that obtained by traditional solvent maceration methods and with that shown by different common synthetic antioxidants. Additionally, antibacterial activity of extracts from the different herbs obtained was determined against different microorganisms. Supercritical extracts from these herbs were efficient in stabilizing sunflower oil; thus, they could represent a valuable natural alternative to synthetic antioxidants. Herbal extracts prove to be a source of compounds with antibacterial activity, with promising applications in the control of microbial deterioration of food.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=bbbbd8fa083a2d4582ab60cc7d0cd816" target="_self"><strong>Vieitez Osorio, Ignacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Maceiras, L.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=178a48bba0993fb17ba1ac64b40d019c" target="_self"><strong>Jachmanian, Ivan</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=426812ce9c2db7dd3c7141ba304d2c4f" target="_self"><strong>Albor&eacute;s, Silvana</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[The Journal of Supercritical Fluids v. 133, 2018. --&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; p. 58-64]]></dcterms:source>
    <dcterms:publisher><![CDATA[Elsevier]]></dcterms:publisher>
    <dcterms:date><![CDATA[2018]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&egrave;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1016/j.supflu.2017.09.025]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6644">
    <dcterms:title><![CDATA[<strong>Antioxidant capacity and NF-kB-mediated anti-inflammatory activity of six red uruguayan grape pomaces</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ORUJO DE UVA]]></dcterms:subject>
    <dcterms:subject><![CDATA[FENOLES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ANTIOXIDANTES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ACOPLAMIENTO MOLECULAR]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2023]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Grape pomaces have a wide and diverse antioxidant phenolics composition. Six Uruguayan red grape pomaces were evaluated in their phenolics composition, antioxidant capacity, and anti inflammatory properties. Not only radical scavenging methods as DPPH&middot; and ABTS&middot;+ were employed but also ORAC and FRAP analyses were applied to assess the antioxidant potency of the extracts. The antioxidant reactivity of all extracts against hydroxyl radicals was assessed with ESR. The phenol profile of the most bioactive extract was analyzed by HPLC-MS, and a set of 57 structures were determined. To investigate the potential anti-inflammatory activity of the extracts, Nuclear Factor kappa-B (NF-&kappa;B) modulation was evaluated in the human colon cancer reporter cell line (HT-29-NF-&kappa;B-hrGFP). Our results suggest that Tannat grapes pomaces have higher phenolic content and antioxidant capacity compared to Cabernet Franc. These extracts inhibited TNF-alpha mediated NF-&kappa;B activation and IL-8 production when added to reporter cells. A molecular docking study was carried out to rationalize the experimental results allowing us to propose the proactive interaction between the NF-&kappa;B, the grape extracts phenols, and their putative anti-inflammatory bioactivity. The present findings show that red grape pomace constitutes a sustainable source of phenolic compounds, which may be valuable for pharmaceutical, cosmetic, and food industry applications.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Fari&ntilde;a, Emiliana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Daghero, Hellen</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Bollati Fogol&iacute;n, Mariela</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://export.cvuy.uy/cv/?e1ba7de0d572172f427d637a61cf7ffedcaca3f4642b955065a2f3a72fb70a03516776171609b3227f51a8c2647cd41dcfe25b5f501e985b684341e0de901a45" target="_blank"><strong>Boido, Eduardo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Cantero, Jorge</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Moncada Basualto, Mauricio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Olea-Azar, Claudio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Polticelli, Fabio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://export.cvuy.uy/cv/?8e4377ca77382678fd5af0d455590aa18a44e65bac89340cfafbbd41152343acd96dc3153f75f2fdf08a92578f213300543d33a6754527876021976e495c507b" target="_blank"><strong>Paulino, Margot</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Molecules v.28, n&deg;9, 2023. -- e3909]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2023]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong>&nbsp;de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:extent><![CDATA[17 p.]]></dcterms:extent>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[<p>Art&iacute;culo</p>
<p>&nbsp;</p>]]></dcterms:type>
    <dcterms:identifier><![CDATA[10.3390/molecules28093909]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6378">
    <dcterms:title><![CDATA[<strong>Antioxidant, antidiabetic, and antiobesity properties, TC7-Cell cytotoxicity and pptake of Achyrocline satureioides (Marcela) conventional and high pressure-assisted extracts</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[COMPUESTOS BIOACTIVOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[METABOLISMO CELULAR]]></dcterms:subject>
    <dcterms:subject><![CDATA[FLAVONOIDES]]></dcterms:subject>
    <dcterms:subject><![CDATA[ACHYROCLINE SATUREIOIDES]]></dcterms:subject>
    <dcterms:subject><![CDATA[COMPUESTOS FENOLICOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2021]]></dcterms:subject>
    <dcterms:abstract><![CDATA[<p>The growing incidence of non-communicable diseases makes the search for natural sources of bioactive compounds a priority for such disease prevention/control. Achyrocline satureioides<br />(&lsquo;marcela&rsquo;), a plant rich in polyphenols and native to Brazil, Uruguay, Paraguay, and Argentina, could be used for this purpose. Data on its antidiabetic/antiobesity properties and cellular uptake of bioactive compounds are lacking. The potentiality of non-thermal technologies such as highhydrostatic<br />pressure (HP) to enhance polyphenol extraction retains attention. Thus, in the present study aqueous and ethanolic marcela extracts with/without assisted-HP processing were chemically characterized and assessed for their in vitro antioxidant capacity, antidiabetic and antiobesity activities, as well as cellular cytotoxicity and uptake on intestinal cell monolayers (TC7-cells, a clone of Caco-2 cells). Aqueous and ethanolic conventional extracts presented different polyphenolic<br />profiles characterized mainly by phenolic acids or flavonoids, respectively, as stated by reverse phase-high-performance liquid chromatography (RP-HPLC) analyses. In general, ethanolic extracts presented the strongest bioactive properties and HP had none or a negative effect on in vitro bioactivities comparing to conventional extracts. TC7-cell viability and cellular uptake demonstrated in conventional and HP-assisted extracts, highlighted the biological effects of marcela bioactive<br />compounds on TC7-cell monolayers. TC7-cell studies showed no HP-induced cytotoxicity. In sum, marcela extracts have great potential as functional ingredients for the prevention/treatment of chronic diseases such as diabetes.</p>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cv/?48a71d2e5134808569068d2724790a8aea8b2933a5fec257ee3e4e79c698c53217947faea852f59905ef92c97b0830d7d801d00a336d676bae44ed023b6adffa" target="_blank"><strong>Fern&aacute;ndez Fern&aacute;ndez, Adriana Maite</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dumay, Eliane</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lazennac, Fran&ccedil;oise</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cv/?4e8790094627dcd20f1718b9bf2b88bd8cea40a68b525e30bf109dc94f7fdba2109c0cf4034470b0b4d5a9f44c2bfe194152e221dd5805d9671e99e3c1a2a2d2" target="_blank"><strong>Migues, Ignacio</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Heinzen, Horacio</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Lema, Patricia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cv/?60a5cc2a5312de1830d131c4661217e33f20c3315cb3ad1f50cfabd222b817df99fca59344a48ccbaeaa278ac153f8ee877607b830a7cb5a0b2404c7b902a1c1" target="_blank"><strong>L&oacute;pez Pedemonte, Tom&aacute;s</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://exportcvuy.anii.org.uy/cv/?7c64fd0475a2077f15b2edfba26c864ffb58e74137469e728a10a1e9f597797565a168ad79a66a0e079ca1f99d19153126e8d3094144e8ab95c1a3e8ff5e8111" target="_blank"><strong>Medrano Fernandez, Alejandra</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Foods&nbsp;v. 10, n&deg; 4, 2021. -- pp. 1-20. -- e893]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2021]]></dcterms:date>
    <dcterms:rights><![CDATA[<p dir="ltr"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p dir="ltr"><span>(Por favor lea este aviso antes de abrir los documentos u objetos)</span></p>
<p dir="ltr"><strong>La legislaci&oacute;n uruguaya protege el derechode autor</strong><span>&nbsp;sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</span></p>
<span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"><strong>ADVERTENCIA:</strong><span>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</span></span>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span id="docs-internal-guid-ab4e821f-7fff-3877-5cb4-7fb14b85b6f7"><span>10.3390/foods10040893 </span></span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/3022">
    <dcterms:title><![CDATA[<strong>Antioxidantes como v&iacute;a de una dieta saludable : evaluaci&oacute;n en entrecruzamientos de mandarinas</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[ANTIOXIDANTES]]></dcterms:subject>
    <dcterms:subject><![CDATA[MANDARINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[DIETA SALUDABLE]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2014]]></dcterms:subject>
    <dcterms:creator><![CDATA[<strong>Viera, Juliana</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Vignale, Beatriz</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curr&iacute;culum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2df81feedac99473a4e536d2623f04c3" target="_blank"><strong>Dellacassa, Eduardo</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=617ff0430e37557fbf5f99096500417c" target="_blank"><strong>Pist&oacute;n, Mariela</strong></a>]]></dcterms:creator>
    <dcterms:source><![CDATA[Revista de la Asociaci&oacute;n de Educadores de Qu&iacute;mica v. 2, 2014. -- p. 50-56]]></dcterms:source>
    <dcterms:publisher><![CDATA[ADEQ]]></dcterms:publisher>
    <dcterms:date><![CDATA[2014]]></dcterms:date>
    <dcterms:rights><![CDATA[<p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Espa&ntilde;ol]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[ISSN : 2301-0991]]></dcterms:identifier>
</rdf:Description></rdf:RDF>
