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                <text>FEMS Yeast Research v.13, 2013. -- p. 189-199</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Thiosemicarbazone derived from 1-indanones as new anti-Trypanosoma cruzi agents&lt;/strong&gt;</text>
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                <text>In the present work, we synthesized a series of thiosemicarbazones derived from 1-indanones with good anti-Trypanosoma cruzi activity. Most of them displayed remarkable trypanosomicidal activity. All the compounds showed nonspecific cytotoxicity on human erythrocytes. The ability of the new compounds to inhibit cruzipain, the major cysteine protease of T. cruzi, was also explored. Thiosemicarbazones 12 and 24 inhibited this enzyme at the dose assayed. This interaction was also studied in terms of molecular docking.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;&#13;
&lt;br /&gt;&#13;
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              <text>Pdf&#13;
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                <text>&lt;strong&gt;Ultrasound assisted extraction of bioactivecompounds in fresh and freeze-dried Vitis viniferacv Tannat grape pomace&lt;/strong&gt;</text>
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                <text>ENOLOGIA&#13;
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                <text>SOLVENTE LIQUIDO-EXTRACCION&#13;
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                <text>VINOS TANNAT&#13;
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA&#13;
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                <text>2020&#13;
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                <text>Tannat red wine residues present a unique polyphenolic composition. Revalorization ofthis residue depends on adequate extraction technologies to assure process sustainability.Influence of temperature (15&amp;minus;60◦C), ultrasound (US) power (0&amp;minus;100 W) and US applicationtime (5&amp;minus;50 min) on Ultrasound Assisted Extraction (UAE) of fresh and freeze-dried Tan-nat grape pomace was evaluated. UAE was performed in a US bath, following extractionkinetics throughout 50 min by assessing: total polyphenol content (TPC), total monomericanthocyanins (TMAC) and total antioxidant capacity (AOC). Additionally, HPLC analysiswas performed to determine extracted compounds&amp;rsquo; profile. Results showed UAE enhancedextraction in both fresh and freeze-dried pomace. In fresh pomace, UAE yielded extracts50% richer in TPC and TMAC on average when compared to conventional extractions, whilein freeze-dried pomace 180% increase in extraction was achieved. In fresh and freeze-driedpomace, US application allowed extraction of different compounds with respect to con-ventional extraction. This work shows that UAE has potential for Tannat grape pomacevalorization, yet UAE conditions should be carefully selected to favour desired extract com-position.&#13;
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                <text>&lt;strong&gt;Gonz&amp;aacute;lez, Mariana&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Barrios, Sof&amp;iacute;a&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Budelli, Eliana&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Lema, Patricia&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Heinzen, Horacio&lt;/strong&gt;</text>
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                <text>Food and Bioproducts Processing v. 124 ,2020.-- p. 378&amp;ndash;386&#13;
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt; (Por favor lea este aviso antes de abrir los documentos u objetos)&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho de autor &lt;/strong&gt;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
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                <text>https://doi.org/10.1016/j.fbp.2020.09.012&#13;
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                <text>&lt;strong&gt;Ultrasonic assisted extraction of Achyrocline satureioides Lam, D.C, (marcela) in aqueous media improves extraction yield and enhances selective bioactive extraction&lt;/strong&gt;</text>
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                <text>This work studied ultrasound assisted extraction (UAE) as a green chemistry technique to improve aqueous extraction of bioactive compounds from marcela (Achyrocline satureioides Lam.), a native plant from South America with reported beneficial health effects. Dried intact marcela inflorescences were extracted using solely water as solvent in an ultrasonic bath, applying 100 and 150 W/L ultrasound power at 40 and 60 &amp;deg;C, respectively. Extraction was followed throughout 30 min by determining antioxidant capacity (AOC) and total polyphenol content (TPC) every 5 min. Extracts were analysed by LC-MS and LC-DAD to identify extracted bioactive compounds and analyse the impact of temperature and ultrasound application on compound profile. Solidliquid extraction at 40 and 60 &amp;deg;C and maceration at room temperature were studied as reference extraction methods. UAE extracts were higher in AOC by 140% and 25% at 40 and 60 &amp;deg;C respectively, compared to solid-liquid extraction. For TPC, UAE showed an increase of 110% and 20% at 40 and 60 &amp;deg;C, respectively. LC results indicated that ultrasound application allowed faster and enhanced hydroxycinnamic acids extraction, whereas an increase in temperature resulted in a more diverse compound profile. UAE could be used to extract caffeic acid when applied at 40 &amp;deg;C.</text>
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&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;br /&gt;&lt;br /&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;br /&gt;&lt;br /&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;br /&gt;&lt;br /&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;br /&gt;&lt;br /&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.</text>
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            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="446848">
                <text>PDF</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="446849">
                <text>Ingl&amp;eacute;s</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="446850">
                <text>Art&amp;iacute;culo</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>doi: 10.1517/13543776.2011.565334</text>
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            </elementTextContainer>
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          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="446852">
                <text>Africa</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
    <tagContainer>
      <tag tagId="1223">
        <name>Africa</name>
      </tag>
      <tag tagId="276">
        <name>Leishmaniasis</name>
      </tag>
      <tag tagId="358">
        <name>Productos farmacéuticos</name>
      </tag>
      <tag tagId="275">
        <name>Tripanosomiasis</name>
      </tag>
    </tagContainer>
  </item>
</itemContainer>
