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                <text>&lt;strong&gt;How Echinococcus granulosus deals with complement&lt;/strong&gt;</text>
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                <text>Here, Ana Mar&amp;iacute;a Ferreira and colleagues discuss the interplay between the larval stages of Echinococcus granulosus and an important effector arm of immunity: the host complement system. During early infection, the parasite activates complement, and hence complement-dependent inflammatory responses. However, on differentiation into the hydatid cyst, the parasite exposes to the host a structure &amp;ndash; the cyst wall &amp;ndash; that does not activate complement strongly. Mechanisms inhibiting complement activation on the cyst wall have been elucidated, contributing to the understanding of how this large, persistent, tissue-dwelling pathogen controls the inflammatory response.</text>
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                <text>Parasitology Today v. 16, , 2000. -- p. 168-172</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho de&lt;/strong&gt; autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>The aim of this work was to investigate the contribution of complement C5-mediated mechanisms, with an emphasis on in&amp;macr;ammation, to host defences against Echinococcus granulosus hydatid disease. Thus, we compared the systemic and local in&amp;macr;ammatory responses induced by the parasite, and the outcome of infection, between congenic C5-suf&amp;reg;cient (B10.D2 n/SnJ) and C5-de&amp;reg;cient (B10.D2 o/SnJ) mice challenged with protoscoleces. Indirect evidence of in-vivo complement activation during the establishment phase was obtained; infection induced serum amyloid P and eosinophil responses which were dependent on C5. Early recruitment of polymorphonuclear cells was not dependent on the presence of C5. The higher capacity of C5-suf&amp;reg;cient mice to recruit eosinophils was also observed during the cystic phase of infection, and mice recruiting more eosinophils developed lower parasite masses. Analysis of the outcome of infection after 8 months showed that C5-suf&amp;reg;cient mice were more resistant to infection than C5-de&amp;reg;cient mice in terms of individuals with no cysts; this trend was not statistically signi&amp;reg;cant. In addition, C5-de&amp;reg;cient mice developed higher numbers of large (&amp;gt; 5mm in diameter) cysts and higher cyst weights than C5-suf&amp;reg;cient mice indicating that C5-mediated mechanisms are detrimental for parasite growth. Taken together, our results suggest that complement, through C5-mediated effectors, contributes to host defences by both restricting the establishment of infection and controlling the growth of established cysts. This contribution may, at least partially, be associated with the ability of C5a to promote eosinophil in&amp;reg;ltration.</text>
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                <text>&lt;strong&gt;Ferreira, A.M&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Breijo, M&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Sim, R.B&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=9d36a9655c915bddd80b664491d73ec8"&gt;&lt;strong&gt;Nieto, Alberto.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Parasite Immunology v. 22, , 2000. -- p. 445-453</text>
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                <text>Blackwell Science Ltd</text>
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            <description>Information about rights held in and over the resource</description>
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              <elementText elementTextId="427880">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Index Descriptors and Abbreviations: Echinococcus; cestode; gluta- tion. This assumption is based, mainly, on their role as a major detoxifithione S-transferase; m-class; induction by xenobiotics; GST, glutathi- cation system in these organisms and on experimental evidence indicatone S-transferase (EC 2.5.1.18); EgGST, GST from E. granulosus; ing that immunization with GSTs confers significant levels of protection EMGST1, GST from E. multilocularis; PSC, protoscolex(ces); PCR, against infection. For this reason, several helminth GSTs&amp;mdash;especially polymerase chain reaction; RT-PCR, reverse transcription-polymerase those from trematodes and nematodes&amp;mdash;have been characterized at the chain reaction; RACE, rapid amplification cDNA ends.</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>H-beta zeolite has been tested for the hydration of dihydromyrcene (DHM) to produce dihydromyrcenol (DHM-OH). By using a non-protic co-solvent like acetone, in order to work under a single phase system, reasonable conversion with excellent selectivity to DHM-OH is obtained, although some double bond isomerization of the terpene is also taking place. The reaction is not controlled by intrapore diffusion, and samples with different crystal sizes gave similar activities and selectivities. However, defect free beta samples with high hydrophobic character are preferred for the reaction due to their improved adsorption properties for non-polar molecules. Working with those materials more than 50% yield of DHM-OH was obtained with a selectivity close to 100%. The influence of zeolite hydrophobicity was further proved in a two-phase liquid reaction system. In such conditions, best results were achieved with the most hydrophobic catalysts.</text>
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&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>In an attempt to understand the molecular basis of the development of Echinococcus granulosus, we have previously isolated several homeobox-containing genes (EgHbx1&amp;plusmn;5). Here we report the characterisation of the EgHbx1 proximal regulatory domain. EgHbx1 codes for an amino acid sequence presenting 90% identity at the homeodomain level with the Drosophila melanogaster NK1-S59 transcription factor. The proximal regulatory domain sequence and the transcription start site were determined. Electrophoretic mobility shift assays using nuclear extracts from protoscoleces revealed the presence of speci&amp;reg;c DNA&amp;plusmn;protein complexes. These results constitute a hint and provide new tools to decipher regulatory cascades during E. granulosus development. # 2000 Australian Society for Parasitology Inc. Published by Elsevier Science Ltd. All rights reserved</text>
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                <text>International Journal for Parasitology v. 30, no. 1, 2000. -- p. 45</text>
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&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>The larva of the green lacewing (Ceraeochrysa cubana) (Neuroptera, Chrysopidae) is a natural predator of eggs of Utetheisa ornatrix (Lepidoptera, Arctiidae), a moth that sequesters pyrrolizidine alkaloids from its larval foodplant (Fabaceae, Crotalaria spp.). Utetheisa eggs are ordinarily endowed with the alkaloid. Alkaloidfree Utetheisa eggs, produced experimentally, are pierced by the larva with its sharp tubular jaws and sucked out. Alkaloid-laden eggs, in contrast, are rejected. When attacking an Utetheisa egg cluster (numbering on average 20 eggs), the larva subjects it to an inspection process. It prods and/or pierces a small number of eggs (on average two to three) and, if these contain alkaloid, it passes "negative judgement" on the remainder of the cluster and turns away. Such generalization on the part of the larva makes sense, because the eggs within clusters differ little in alkaloid content. There is, however, considerable between-cluster variation in egg alkaloid content, so clusters in nature can be expected to range widely in palatability. To check each cluster for acceptability must therefore be adaptive for the larva, just as it must be adaptive for Utetheisa to lay its eggs in large clusters and to apportion alkaloid evenly among eggs of a cluster.</text>
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                <text>Proceedings of the National Academy of Sciences of the United States of America v. 97, no. 4, 2000. -- p. 1634-1639</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Three copper(II)-rhenium(IV) bimetallic complexes of formula [ReCl(4)(mu-ox)Cu(phen)(2)] (1), [ReCl(4)(mu-ox)Cu(phen)(2)].CH(3)CN (2), and [ReCl(4)(mu-ox)Cu(terpy) (H(2)O)][ReCl(4)(mu-ox)Cu(terpy)(CH(3)CN)] (3) (ox = oxalate anion, phen = 1,10-phenanthroline, and terpy = 2,2':6,2"- terpyridine) have been synthesized and their crystal structures determined by single-crystal X-ray diffraction. Complex 1 crystallizes in the triclinic system, space group P(-1), with a = 9.776(2), b = 11.744(3), c = 14.183(3) A, alpha =102.09(2) degrees, beta = 109.42(2) degrees, gamma = 107.11(2) degrees, and Z = 2, whereas 2 and 3 crystallize in the monoclinic system, space groups P2(1)/n and P2(1)/c, respectively, with a = 12.837(3), b = 17.761(4), c = 12.914(3) A, beta = 91.32(2) degrees, and Z = 4 for 2, and a = 8.930(2), b = 18.543(4), c = 27.503(6) A, beta = 94.67(2) degrees, and Z = 4 for 3. The structures of 1 and 2 are made up of neutral [ReCl(4)(mu-ox)Cu(phen)(2)] bimetallic units. Re(IV) and Cu(II) metal ions exhibit distorted octahedral coordination geometries, being bridged by a bis(bidentate) oxalato ligand. The presence of acetonitrile molecules of crystallization in 2 causes a somewhat greater separation between the bimetallic complexes and a different packing of these units in the crystal structure with respect to 1. The copper-rhenium separation across oxalato is 5.628(2) in 1 and 5.649(3) A in 2. The structure of 3 is made up of two different and neutral bimetallic units, [ReCl(4)(mu-ox)Cu(terpy)(H(2)O)] and [ReCl(4)(mu-ox)Cu(terpy)(CH(3)CN)]. In the first one, the oxalate group behaves as a bis(bidentate) ligand occupying one equatorial and one axial position in the elongated octahedral environment of Cu(II). The water molecule is axially coordinated. In the second one, the oxalate group behaves as a bidentate/monodentate ligand occupying the axial position in the square pyramidal environment of Cu(II). The acetonitrile molecule occupies a basal coordination position around the copper atom. These units are arranged in such a way that a chlorine atom of the first unit (Cl(1)) points toward the copper atom (Cu(2))of the second one (3.077(2) A for Cl(1)(.)Cu(2)), forming a tetranuclear species. The copper-rhenium separation across bis(didentate) oxalato is 5.504(3) A, whereas that through bidentate/monodentate oxalato is 5.436(2) A. The magnetic behavior of 2 and 3 has been investigated over the temperature range 1.8-300 K. A very weak and nearly identical antiferromagnetic coupling between Re(IV) and Cu(II) through bis(bidentate) oxalato occurs in 2 (J = -0.90 cm(-1)) and 3 (J = -0.83 cm(-1)); it is ferromagnetic in 3 through both the bidentate-monodentate oxalato (J = +5.60 cm(-1)) and the chloro (J = +0.70 cm(-1)) bridges.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt; sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
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                <text>Three novel neutral complexes containing the [ReO]3+ core have been prepared starting from K2ReBr6. Complexes with general formula [ReO(OCH3)(ox)(L)] (ox=oxalate; L=2,2&amp;prime;-bipyridine (bipy), 1,2-bis(diphenylphosphino)ethane (dppe) or cis-1,2-bis(diphenylphosphino)ethylene (dppee)) have been obtained and characterized. The molecular structures of [ReO(OCH3)(ox)(bipy)] and [ReO(OCH3)(ox)(dppe)] have been determined of single-crystal X-ray analysis. The structure of the complexes consists of a six-coordinated rhenium atom bonded to two trans-oxygen atoms, one of the [ReO]3+ core and one from a methoxy group. One oxalate ligand and a neutral diamine or diphosphine make the equatorial plane.</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Mini reviews in medicinal chemistry v. 1, 2001. -- p. 219-31</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>The nitrito to nitro spontaneous isomerization reaction of the complexes [Co(MeNH2)5(ONO)]2+, cis-[Co(MeNH2)(NH3)4(ONO)]2+, trans-[Co(MeNH2)(NH3)4(ONO)]2+, trans-[Co(en)2(NH3)(ONO)]2+, trans-[Co(en)2(MeNH2)(ONO)]2+, trans-[CoL14(ONO)]2+ and cis-[CoL14(ONO)]2+ has been studied as a function of temperature and pressure. The corresponding base-catalyzed reactions of the systems with monodentate ligands have also been studied as a function of temperature and pressure. The results produce thermal and baric activation parameters that can be as a whole related to an ordered expansion to go to the transition state. This is particularly true for the (N)5 macrocyclic L14 systems (L14=6-methyl-1,4,8,11-tetraazacyclotetradecane-6-amine) where the importance of hydrogen bonding becomes evident as for related studies. For systems with a high trans influence the results indicate a clear increase of the degree of dissociation to go to the transition state, very much in line with what has been observed for previously studied substitution reactions. Thus, the results agree with the fact that the nitrito to nitro isomerization reactions, in spite of being of intramolecular nature as established by very clear results, follow a reactivity pattern very similar to that observed for the substitution reactions of neutral ligands on the same complexes. That is, the transition state of the process has a high resemblance to that of the dissociatively activated substitution reactions of the Co(III) complexes.</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>The immobilisation of b-galactosidase and amyloglucosidase (AMG) by means of physical adsorption on to bone powder is described. The in&amp;macr;uence of the enzyme load, applied to the support on immobilisation, yield and eciency, has been determined. The immobilisation process improved the thermal stability of b-galactosidase (at 37�C), while immobilised AMG displayed a sta- bility (at 55�C) similar to that of the soluble enzyme. The apparent KM (Kapp) values have been determined for both derivatives, for the b-galactosidase derivative KM was 3 mM using the arti&amp;reg;cial substrate ONPG and, for the AMG derivative, it was 1 mg/ml using soluble starch as substrate. The extent of lactose hydrolysis achieved, batchwise, with b-galactosidase derivatives acting on lactose buered solutions, whey, whey permeates and skimmed milk, was in the range of 90% and decreased to 50% after 3 reuses. The conversion of 30% (w/v) lique&amp;reg;ed cassava starch achieved with the AMG derivative was 98% until the 11th reuse, and over 95% until the 20th reuse. # 2000 Elsevier Science Ltd. All rights reserved.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Berasain, P., Carmona, C., Frangione, B., Dalton, J. P., and Gon&amp;tilde;i, by cathepsins on digested proteins, its actions on IgG subclasses were F. 2000. Fasciola hepatica: Parasite-secreted proteinases degrade all specific and restricted; thus, all the fragments produced could be potenhuman IgG subclasses: Determination of the specific cleavage sites tially involved in the mechanisms used by the parasite to evade the and identification of the immunoglobulin fragments produced. Experi- host immune response. q 2000 Academic Press mental Parasitology 94, 99&amp;ndash;110. The study was focused on the relation- Index Descriptors and Abbreviations: Fasciola hepatica; trematode; ship of Fasciola hepatica-secreted proteinases and human IgG sub- excretion&amp;ndash;secretion (E/S); cysteine proteinase; cathepsin L1 (CL1); classes. Each IgG was incubated at different pH values and lengths of cathepsin L2 (CL2); newly excysted juveniles (NEJs); IgG subclasses; time with either the adult parasite excretion&amp;ndash;secretion products or the enzyme specificity; cathepsin L cleavage site; immune evasion; 7- purified cysteinyl proteinases cathepsin L1 and cathepsin L2. The Ig aminomethylcoumarin (NHMec); Coomassie brilliant blue (CBB); sofragments produced were isolated and characterized by Western blot dium dodecyl sulfate&amp;ndash;polyacrylamide gel electrophoresis (SDS&amp;ndash; analysis, and the specific cleavage sites were determined by amino PAGE); heavy (H); light (L). acid sequence analysis. Parasite excretion&amp;ndash;secretion products and both cathepsins L produced similar degradation patterns and cleaved all human IgG subclasses at the hinge region, yielding at pH 7.3 and 378C Fab and Fc fragments in the case of IgG1 and IgG3 or Fab2 and Fc in IgG2 and IgG4. While IgG1 and IgG3 were readily degraded by E/ S products either in the presence or in the absence of reducing agents, INTRODUCTION IgG2 and IgG4 were resistant to proteolysis and were only digested in the presence of 0.1 M dithiothreitol. The cathepsins L needed the presence of dithiothreitol to digest IgG1, IgG2, and IgG4 whereas IgG3 was identically cleaved under both reducing and nonreducing Fasciola hepatica, the common liver fluke, is the causconditions. The main cleavage sites produced by E/S products, CL1, ative agent of fasciolosis in mammals. When infecting rumior CL2 were located at the positions peptide bonds: His237-Thr238, nants, like cattle and sheep, it causes significant economical Glu237-Cys239, Gly233-Asp234, and Ser241-Cys242 for g 1, g 2, g 3, or g 4, respectively. The enzymes gave additional splitting sites on the losses in agricultural-based countries. Moreover, recent remiddle hinge of IgG3 to produce shorter Fc fragments and also produce ports indicate that fasciolosis, as a zoonosis that affects Fd degradation of the IgG4. No cleavage specificity differences were humans, is more important than previously thought (Bjorland found between CL1 and CL2, but they differed in the kinetics of IgG3 et al. 1995; Esteban et al. 1997). The trematode burrows degradation. By lowering the pH, only the E/S products produced through the gut wall of its mammalian host and spends concomitant destruction of the Fc while preserving the Fab portion. Under all the conditions assayed the enzymes produced an Fc8-like approximately 2 months migrating within the liver before fragment of 14&amp;ndash;15 kDa corresponding to the whole CH3 domain of entering the bile ducts where they reach sexual maturation the immunoglobulin. Contrary to the extensive degradation produced</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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            <name>Title</name>
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                <text>&lt;strong&gt;Vibrational spectra of the Cu (II) complexes of aspartic and glutamic acids&lt;/strong&gt;</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="426881">
                <text>ESPECTROSCOPIA</text>
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              <elementText elementTextId="426882">
                <text>COMPLEJOS DE COBRE</text>
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                <text>ACIDO GLUTAMICO</text>
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                <text>ACIDO ASPARTICO</text>
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              <elementText elementTextId="426885">
                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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              <elementText elementTextId="426886">
                <text>2000</text>
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          <element elementId="87">
            <name>Abstract</name>
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              <elementText elementTextId="426887">
                <text>The infrared and Raman spectra of Cu(asp).2H20 and Cu(glu).2H20 (asp = L-aspartate; glu = L-glutamate) were recorded and discussed in relation to their crystal structures. Some comparisons with Cu(I1) complexes of other amino acids are also made</text>
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          <element elementId="39">
            <name>Creator</name>
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              <elementText elementTextId="426888">
                <text>&lt;strong&gt;Baran, E&lt;/strong&gt;</text>
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              <elementText elementTextId="426889">
                <text>&lt;strong&gt;Wagner, C.C&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=1be7431d37af92df16867e8519adf042"&gt;&lt;strong&gt;Torre, Mar&amp;iacute;a H&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=37cace18c8d1da50d33d6bd4f8f1a607"&gt;&lt;strong&gt;Kremer, Eduardo&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Kogerler, P&lt;/strong&gt;</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="426893">
                <text>Acta Farmac&amp;eacute;utica Bonaerense v. 19, no. 3, 2000. -- p. 231-234</text>
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          <element elementId="45">
            <name>Publisher</name>
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              <elementText elementTextId="426894">
                <text>Colegio de Farmac&amp;eacute;uticos de la Provincia de Buenos Aires</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="426895">
                <text>2000</text>
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          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
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              <elementText elementTextId="426896">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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            <name>Format</name>
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                <text>PDF</text>
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          <element elementId="44">
            <name>Language</name>
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              <elementText elementTextId="426898">
                <text>Ingl&amp;eacute;s</text>
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                <text>Art&amp;iacute;culo</text>
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            <name>Identifier</name>
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              <elementText elementTextId="426900">
                <text>ISSN 0326-2383</text>
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      <tag tagId="3076">
        <name>Acido glutamico</name>
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      <tag tagId="50">
        <name>Complejos de cobre</name>
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      <tag tagId="60">
        <name>Espectroscopía</name>
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