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                <text>The objective of the current study was to examine the safe use of a daily standard dose of omeprazole (20 mg) regarding magnesium levels in blood in hospitalized patients. A total of 51 patients (15 women, 36 men) with different characteristics (pathologies, comedications, age, habits, etc) and taking a standard dose of omeprazole for more than three months were included. 17.6 % of the patients showed mild hypomagnesemia but we concluded that the observed low levels of this electrolyte could be attributed to comedications, age and different pathologies rather than the 20-mg dose of omeprazole. So, hypomagnesemia does not eliminate proton-pump inhibitors as a reasonable option; it just requires clinicians to be aware of this problem and use them safely at conventional doses.</text>
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                <text>&lt;strong&gt;Maldonado, Cecilia&lt;/strong&gt;</text>
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                <text>International Journal of Pharmacy v. 5, no. 2, 2015. -- p. 315-321</text>
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                <text>Hemos estudiado, tres muestras de limos, provenientes de Strasbaurg, Pontenvaux, y el Dpto. de Belgrano (Rep. Arg). Las muestras "tal cual", han sido examinadas al microscopio polarizante. Las diversas fracciones resultantes del an&amp;aacute;lisis granulom&amp;eacute;trico se han estudiado mediante m&amp;eacute;todos tales como R.X., A.T.D:, A.T.P., capacidad de intercambio de bases, etc.</text>
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                <text>&lt;strong&gt;Go&amp;ntilde;i, J.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Esquevin, J.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Malycheff, V.&lt;/strong&gt;</text>
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              <elementText elementTextId="644868">
                <text>&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;br /&gt;&lt;br /&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;br /&gt;&lt;br /&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;br /&gt;&lt;br /&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;br /&gt;&lt;br /&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.</text>
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                <text>The cyclization of Schiff bases derived from phenethylamines to 1-methyl-, 1-phenyl- and 1-benzyl-tetrahydroisoquinolines has been examined. It was confirmed that a free OH group para or ortho to the place of ring closure is of fundamental importance for the possibility of cyclization under neutral or weekly acid conditions. The cyclization reaction with Schiff bases of phenylacetaldehydes synthesized via Darzens reaction is very easy. The IR, UV and NMR spectra of the Schiff bases and tetrahydroisoquinolines have been compared and from this methods deduced for following up the ring closure reaction.&lt;br /&gt;&lt;br /&gt;</text>
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                <text>&lt;strong&gt;Filling dynamics of the Brindley&amp;rsquo;s glands in the blood-sucking bug Triatoma infestans (Hemiptera: Reduviidae)&lt;/strong&gt;</text>
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                <text>&lt;span&gt;The filling dynamics of exocrine defensive glands is an important component of the defensive capacity of an insect in its natural environment. We studied the filling state and reloading rate of the Brindley's glands in the haematophagous Chagas disease vector Triatoma infestans (Hemiptera: Reduviidae). Quantitative analyses of isobutyric acid, the main secretion component, were carried out with glands dissected from adults under different scenarios of development, number of discharging events and feeding conditions. The alarm-pheromone function of the gland secretion was also assessed in bioassays with conspecific nymphs. Although pharate adults have their glands completely developed, these were not full until imaginal ecdysis. If kept undisturbed, the adults maintained a constant gland load, and discharged about 75% of the gland contents upon one disturbance event. While the glands can be discharged several times, full replenishing was not complete after one week, unless the insect had access to food. The escape behavior of nymphs in bioassays correlated with the chemical analyses, with nymphs showing significant avoidance only toward gland discharges from undisturbed or disturbed/fed adults. The results are discussed in reference to the feeding frequency and gregarious behavior of T. infestans under natural conditions, which suggest a relevant role of the filling dynamics of the Brindley's glands in the intraspecific communication of the insect.&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Pallotini, Florencia&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;&lt;a href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=8ca340da794ac0eade285d2d2721ec5d" target="_blank"&gt;Gonz&amp;aacute;lez, Andr&amp;eacute;s&lt;/a&gt;&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Manrique, Gabriel&lt;/strong&gt;</text>
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                <text>&lt;span&gt;Journal of Insect Physiology&amp;nbsp;v. 71, 2014. -- p. 122-127&lt;/span&gt;</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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                <text>Animal cells contain a pool of inositol phosphates whose biological function is still under current investigation. Ins(1,2,3)P3 is probably an important safe chelator of iron cations not strongly bound to proteins. In order to clarify its biological functions, Ins(1,2,3)P3 chemistry under physiological conditions must be completely elucidated. The protonation and complexation behaviour of Ins(1,2,3)P3 has been recently studied under these conditions by potentiometry. Under simulated physiological conditions it forms the protonated species H2L4� and H3L3�. The presence of high concentrations of potassium in intracellular compartments causes the formation of two predominant Ins(1,2,3)P3 complexes: [K(HL)]4� and [K(H2L)]3�, in the absence of iron. In this work we expand part of this macroscopic knowledge to the inframolecular level, by 31P NMR measurements and focusing on the protonation and complexation of this biologically relevant molecule to potassium. We complete this study with theoretical calculations which lead us to predict the geometries of every form of the ligand and their relative stabilities. The influence of the ring conformation in protonated and complexed forms is also discussed.</text>
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                <text>&lt;a title="Curr&amp;iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=f31ba94f764507db0d42d457038dd734" target="_blank"&gt;&lt;strong&gt;Veiga, Nicolas&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>With the aim to improve the performance of enzyme bound to hydrophilic solid phases, their immobilization with polyethylene glycol (PEG) tether have been studied. Sweet potato �-amylase, which hydrolyses the high molecular weight substrate starch and �-galactosidase, which acts on low molecular weight substrates, were used as model enzymes and beaded thiol&amp;ndash;agarose as solid phase. Several two step methods for the introduction of the tether using a bis-oxirane homobifunctional PEG as well as a heterobifunctional derivative with a hydroxysuccinimide ester and a maleimide group have been evaluated. Amino groups, native and de novo thiol groups in the enzymes were utilized for immobilization. The best approach was found to be to first introduce the PEG derivative via one of its reactive groups to the enzyme. Subsequently the formed conjugate was bound to the solid phase by the remaining reactive group. Attempts to first introduce the PEG tether into the solid phase were not successful. Ahigh degree of substitution with PEG chains on the enzyme leads to high immobilization yields for both �-amylase and �-galactosidase, but relatively lower gel-bound activity for the former enzyme which is acting on a high molecular weight substrate and thus more sensitive for steric shielding effects. With optimal degree of PEG substitution (which occurred at five times molar excess of the heterobifunctional reagent) the gel-bound activity of �-amylase was increased from 12% (for the derivative without tether) to 31%.</text>
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                <text>&lt;strong&gt;Manta, Carmen&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Ferraz, Natalia&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Bentancor, Laura&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Antunes, Gabriela H&amp;ouml;nnicke&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Batista-Viera, Francisco&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Carlsson, J&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Caldwell, K&lt;/strong&gt;</text>
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                <text>Enzyme and Microbial Technology v. 33, no. 7, 2003. -- p. 890-898</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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Incluye únicamente trabajos hasta el año 2023. Los trabajos posteriores se encuentran disponibles en el Repositorio Colibrí.</text>
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                <text>&lt;strong&gt;Dificultades en el aprendizaje de la Qu&amp;iacute;mica Organica a nivel Universitario relacionadas con los conocimientos adquiridos en Bachillerato&lt;/strong&gt;</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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                <text>Objective: Systemic inflammatory response syndrome is characterized by increased urinary excretion of selenium and low serum concentration. Repletion by parenteral selenite is the most efficacious form of supplementation. However, the optimum safe dose and mode of administration remain controversial. We aimed to determine pharmacokinetic and pharmacodynamic profiles of selenite and estimate a safe dose to optimize selenium status. Methods: A prospective, randomized, pilot study in 20 patients with systemic inflammatory response syndrome compared a high-dose (HD) group that received a loading dose of selenium as selenite 15.18 mmol over 2 h and thereafter 10.12 mmol/d as a continuous intravenous infusion (CIV) for 10 d with a very&amp;ndash;high-dose (VHD) group that received a loading dose of 25.30 mmol over 2 h and thereafter 20.24 mmol as a CIV for 10 d. Clinical outcome was evaluated by length of stay in the intensive care unit, incidence of ventilator-associated pneumonia, and Sequential Organ Failure Assessment score. Results: Patients in group HD (n &amp;frac14; 10, age 54 � 23 y) had an Acute Physiology and Chronic Health Evaluation II score of 23 � 5 and a Sequential Organ Function Assessment score of 10 � 2. Those in group VHD (n &amp;frac14; 10, age 41 � 19 y) had scores of 21 � 7 and 8 � 3, respectively. Pharmacokinetic concentration/time curves for serum selenium overlapped but were independent of dose, whereas the pharmacodynamics were different, showing maximum glutathione peroxidase activity only with VHD. Glutathione peroxidase decreased after day 7 independently of the selenium dose. Clinical outcomes were similar in both groups. Conclusion: A bolus loading dose of selenite providing 2000 mg of selenium (25.30 mmol) followed by a CIV of 1600 mg/d (20.24 mmol/d) for 10 d is most effective at returning serum selenium to physiologic levels and safely maximizing glutathione peroxidase activity</text>
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                <text>&lt;strong&gt;Manzanarez, William&lt;/strong&gt;</text>
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                <text>Nutrition v. 26, no. 6, 2010. -- p. 634-640</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;External preference mapping of commercial antiaging creams based on consumers&amp;acute;responses to a check-all-that-apply question&lt;/strong&gt;</text>
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                <text>Due to the increasing demand for antiaging products, cosmetic companies need to count on reliable methodologies for new product development. In this context, the aim of the present work was to determine whether external preference mapping based on consumers&amp;rsquo; responses to a check-all-that-apply (CATA) question was applicable for studying consumers&amp;rsquo; preferences for commercial antiaging cosmetic creams. Six commercial antiaging creamswere evaluated by a panel of 69 consumers, who were asked to indicate their overall liking and to answer a CATA question. Highly significant differences were found in the frequency in which consumers used 26 out of the 42 terms of theCATAquestion.The application of external mapping on the samples&amp;rsquo; configuration from the multiple factor analysis performed on CATA counts enabled a quick identification of regions of maximum liking within the sensory space defined by the evaluated samples and the drivers of liking responsible for consumers&amp;rsquo; preferences.</text>
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                <text>Journal of Sensory Studies v. 26, 2011. -- p. 158-166</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>In the present work the performance of global projective mapping and partial projective mapping based on texture and flavor for sensory characterization of a novel food category (satiating food product)was compared. Eight different fresh-cheese pie formulationswere designed to obtain different sensory (principally texture) characteristics which could affect expected satiating perception. Three groups of consumers evaluated the samples using one of the following methodologies: global projective mapping (G-PM) (n = 47), partial projective mapping based on flavor (F-PM) (n=53), and partial projective mapping based on texture (T-PM) (n=61). In addition, the expected satiating capacity of each cheese pie sample was scored on a nine-point scale. Results showed that the vocabulary used by consumers for describing the sensory characteristics of samples did not largely differ between global and partial projective mapping tasks. However, T-PM and F-PM tasks provided more detailed information than G-PM in each specific modality. Results suggested that when consumers performed the global projective mapping task they mainly took into account flavor characteristics for evaluating global similarities and differences among samples. In addition, hedonic attributes were more frequently mentioned in G-PM. Fresh cheese, sugar, corn starch and egg were the basic ingredients that conferred the fresh-cheese pies their typical, characteristic flavor and texture. The addition ofwhey or soy proteins,wheat bran or glucomannan increased expected satiating capacity which could be related to changes in texture (harder, more compact) leading to longer orosensory exposure. The addition of glucomannan caused the largest changes in the sensory characteristics of the cheese pies which in turn would be related to a decrease in perceived flavor intensity. Studying the interplay between formulations, sensory characteristics, expected satiating capacity and consumer liking could largely contribute to the development of this novel food category.</text>
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                <text>&lt;strong&gt;Marcano, Johanna&lt;/strong&gt;</text>
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                <text>Food Research International v. 67, 2015. -- p. 323-330</text>
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                <text>&lt;p align="LEFT"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p style="margin-bottom: 0cm;"&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
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        <name>Queso</name>
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                  <text>Tesis de doctorado, maestría, trabajos de diploma y monografías técnicas</text>
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                  <text>Versiones electrónicas de las tesis de doctorado, maestría y trabajos de diploma de la Facultad de Química, Universidad de la República (UdelaR).&#13;
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                <text>&lt;strong&gt;Caracter&amp;iacute;sticas de algunos cl&amp;aacute;sicos vinos europeos&lt;/strong&gt;</text>
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                <text>URUGUAY</text>
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                <text>TECNOLOGIA QUIMICA</text>
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                <text>&lt;strong&gt;Marchelli Brivio, Esteban A.&lt;/strong&gt;</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Montevideo : UdelaR-Facultad de Qu&amp;iacute;mica</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
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                <text>&lt;p&gt;&lt;em&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt; &lt;/em&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;em&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&lt;/em&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Proteolytic activity in hydatid cyst fluid, cyst membranes and protoscoleces of E. granulosus was analyzed by electrophoresis in gelatin-containing polyacrylamide gels, including characterization with a set of protease inhibitors. All contained metalloproteinases in the range 60-120 kDa, with neutral/alkaline pH optima. Major activity was observed in hydatid fluid and the membranes (five bands) with both exhibiting similar electrophoretic patterns. The samples prepared from protoscoleces shared only some of these bands.</text>
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                <text>International Journal for Parasitology v. 21, no. 6, 1991. -- p. 743-746</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DDRs are uniquely positioned to function as sensors for extracellular matrix (ECM) and to regulate a wide-range of cell functions from migration and proliferation to cytokine secretion and ECM homeostasis/remodeling. While activation of DDRs by ECM collagens is required for normal development and tissue homeostasis, aberrant activation and function of these receptors following injury or in disease is detrimental. Both DDRs are indicated to play key roles in development and metastasis of various types of cancer. In spite of this, the mechanisms whereby DDRs contribute to tumor formation and cancer progression are poorly understood. Among reproductive system cancers, epithelial ovarian cancer (EOC) and prostate cancer (PCa) result in high rates of morbidity and mortality. In EOC and PCa, atypical expression of DDRs are indicated to function in malignancy and metastasis. The molecular mechanisms underlying how DDRs contribute to these and other pathologies need to be understood to find new markers and for development of therapeutic agents for treatment of disease. This is particularly the case for EOC in which mechanisms explaining the atypically high levels of DDR1 at initial and late stages of disease have not been described. We first outline studies showing an essential role for DDR2 in steroidogenesis and gamete development in ovary and testes. We then focus on what is known on the role of DDR1 and DDR2 in PCa and DDR1 in EOC. Finally, we speculate on possible functions DDR1 could be playing in different stages of EOC disease. Interactions between ECM proteins and cell surface receptors are well-known to play key roles in regulation of cell behavior and determining physiological function. The switch from DDR2 expression in healthy ovaries to that of DDR1 in initial and late stages of EOC disease provides an experimental system to investigate to what extent ECM and DDR signaling enables malignant transformation.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Supercapacitors have been studied due to their promising as powerful storage devices. The development of highly efficient electrodes is one way to manufacture supercapacitors with high energy and power efficiencies. Binary composites based on activated carbon fiber felt (ACFF) and polypyrrole (PPy) have been investigated to increase capacitance performance. ACF, when applied as a bulk electrode has limited electric characteristics while the PPy suffers from limited stability during cycling that reduces the initial performance. Based on the synergism effect, this work proposes the production of a binary composite based on ACFF produced from a low-cost precursor textile polyacrylonitrile (textile PAN) and the facile synthesis of PPy from the chemical route of polymerization. The binary composite formed by a 3D network with the interconnection of a more conductive form of PPy coated on ACFF was obtained. The resulting architecture was determinant to significantly increase the energy storage capacities when compared to the bulk ACFF electrode. From the galvanostatic charge and discharge curves, cyclic voltammetry and electrochemical impedance, the obtained composite had a specific capacitance about 302 F g&amp;minus; 1 associated with low resistance and to a good density of energy and power.&#13;
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                <text>Solidagenone |b there are two independent molecules in the asymmetric unit which are almost identical. The A ring in both molecules are slightly distorted chairs. The B rings have a sofa conformation. The two fused rings show a cis form of coupling. Despite the disorder both furan rings are planar. The hydroxyl groups are involved in hydrogen bonds with the carbonyl O atoms.</text>
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