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                <text>Se describe la composici&amp;oacute;n de la cera epicuticular de Dasphyllum excelsum. La cera est&amp;aacute; formada por alcoholes libres (24,8 por ciento) |b aldehidos (12,6 p.ciento) |b hidrocarburos (19,2 p.c.) |b hidroxi&amp;aacute;cidos (15,1 p.c.) |b &amp;eacute;steres (6,8 p.c.) y &amp;aacute;cidos libres (6,0 p.c.). El principal constituyente de las fracciones de alcoholes (libres y esterificados) es el lupeol.</text>
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                <text>Laboratorios Mixim S.A.</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>First |b we describe the isolation of three new diterpenoids with a hydroazulene skeleton |b dictyotriol C(1)&amp;nbsp; D(2) |b and E(3). as well as the previously known pachydictyol A(4)&amp;nbsp; dictyol B(5) dictyol C(6)&amp;nbsp; and dictyotadiol(7)&amp;nbsp; from a Dictyota sp. The structures of the new diterpenoids 1-3 were proposed on the basis of their spectral data and confirmed by chemical transformation of dictyol B(5). This is followed by absolute stereochemistries of the new compounds as well as that of the known dictyol B(5) and dictyotadiol (7) were determined. These absolute configurations were opposite to that reported for pachydictyol A(4).</text>
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                <text>&lt;strong&gt;V&amp;aacute;zquez, J&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Chang, M&lt;/strong&gt;</text>
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                <text>Journal of Organic Chemistry&amp;nbsp; v. 53, no. 21, 1988. -- p. 4797-4800</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DOI: 10.1021/jo00255a025</text>
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                <text>CNDO/2 calcns. were used to study the interaction of N- methylglyoxalimine with dipeptide. Bond angles and distances and the charge densities of 3 zones of the complex formed are given. The effect of a F- ion on the charge d. was also studied. A transfer of charge throughout the complex was obsd. A greater interaction in the triplet state of the complex than in the singlet state is postulated. The results are discussed in relation to the theory involving electronic charge d. of proteins in carcinogenesis.</text>
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>Tambo Colorado is one of the most impressive archaeological sites in the Southern Peruvian coast, because of its stunning architecture, its extraordinary pictorial decoration, and its strategic location in the section of the Great Inca Road. The Research Project Tambo Colorado considers necessary to conduct a comprehensive analysis encompassing nature of the materials (archaeometric analysis) as well as a proper understanding of their conservation status of its architecture. In this regard interdisciplinary research provides the necessary tools to achieve these goals. For this reason our team is integrated by archaeometrists, engineers, conservators and archaeologists. Due to of this transdisciplinary approach, one of the main objective is the study of painting technology developed by the craftsmen of the site. The first results obtained, thanks to an analytical strategy combining observation and elemental and structural analysis (colorimetry, SEM-EDS, XRF, XRD and SXRD), allow us to identify the coloring materials used. These data enabled to reconstruct the operational chain followed to elaborate the murals (since the pigments extraction to the making of the murals) but also to consider and develop a suitable surfaces conservation plan. You will find enclosed an abstract image which legend and copyright are: Tambo Colorado, Pisco Valley, Peru (&amp;copy; CNRS/IFEA/C. Anaya Gautier/PRTC)</text>
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                <text>Fatty acids&amp;rsquo; ethyl and methyl esters are not natural components of edible vegetable oils and therefore should not be present in virgin olive oils. Among the quality requir ements for extra virgin o live oils, the International Olive Council (IOC) Norm, 2 015 review, set limits for the ethyl ester content at &amp;le; 435 ppm for the 2014/2015 and 2015/2016 harvests and at &amp;le; 30 ppm for the 2016/2017 harvest. The purpose of this paper is to: (a) determine th e alkyl ester content in two extra virgin olive oils (of th e Arbequina and Coratina varieties) as parame ters of quality at the moment of their el aboration and to assess the length of their shelf life, over a 12 month period at room temper ature; (b) determine extra virgin olive o ils&amp;rsquo; free alcohols conten t as these may est erify due to the free fatty acids present during storage. After 6 months of storage, the Arbequina oil&amp;rsquo; s ethyl ester content was 32 ppm, and the Coratina&amp;rsquo;s was 46 ppm. As a result, the shelf life for both was only about half a year (labeling usually indicates it must be c onsumed &amp;ldquo;before 1 year&amp;rdquo;). However, parameters related to oxidation (peroxide index, K 232, K 270 and ∆ K) remained within the limits set by the International Olive Council (IOC) throughout the year. In conc lusion: ethyl ester content is a very fine parameter for asse ssing the quality of extra virgin in an olive oil and determining the length of its shelf life.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Baccharis trimera (Less.) DC is a South American plant that in folk medicine is considered to produce reduction in blood pressure. One aspect of this putative effect is the vasorelaxation. The aim of this work was to evaluate the ability of a B. trimera extract to relax rat aortic rings precontracted with noradrenaline. As the infusion is the usual way of intake of this plant, an infusion of B. trimera was prepared using 100g of the plant (leaves) boiled in water, frozen and lyophilized. Working solutions were prepared using different concentrations of the dried extract diluted in Krebs Henseleit solution. It was proved that the infusion relaxed the aortic rings in a dose dependent manner 100 minutes after adding the extract to the bath. Considering as 100% the maximum contraction achieved with noradrenaline, a relaxation of 101.1&amp;plusmn;2.3% was observed with the highest dose of the infusion used in these experiments (0.32mg/mL). While in control rings relaxation was 12.9&amp;plusmn;2.4%. In aortic rings denuded from endothelium the percentage of vasoralaxation did not show statistically significant differences when compared to intact rings. These data support the hypothesis of a vasorelaxant effect of this plant and constitutes the first approach to the scientific basis of a potential antihypertensive effect. Keywords: Hypertension, Cardiovascular, Traditional medicine, Meso-and Southtern American, Baccharis trimera, Vasorelaxation, Aortic rings. Discover the world's research</text>
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                <text>Natural Product Communications v. 11, no. 3, 2016. -- p. 283-286</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este&lt;/p&gt;</text>
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                <text>T wo monovarietal extra virgin olive oils (Arbequina and Coratina), produced in Uruguay, were studied over a period of 12 months storage in amber bottles at 30 &amp;ordm;C. P eroxide index, K 232 , K 270 , ∆K, OSI induction time did not exceed the maximum limits set by the International Olive Council (IOC ) during the entire period. However, the content of ethyl esters increase d with storage time and it is in relation with the shelf life. The International Olive Council (IOC) establishes the limits in the content of ethyl esters &amp;le; 35 ppm. T he Coratina oil ceased to be extra virgin quality after 6 months of storage due to its content of ethyl esters (46 ppm), and the Arbequina oil after 9 mo nths (52 ppm). Taking into consideration their content of ethyl esters, both the Arbequina and Coratina oils showed a very short shelf life less than six months. T he determination of ethyl ester content proved to be a sensitive method for determining the l oss of quality of extra virgin olive oils</text>
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                <text>Journal of Food Research v. 5, no. 5, 2016. -- p. 88-94</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Bibliografía Nacional Química</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Product spaces derived from projective mapping and CATA questions :&amp;nbsp; Influence of replicated assessments and increased number of study participants&lt;/strong&gt;</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>COMPORTAMIENTO DEL CONSUMIDOR</text>
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                <text>EVALUACION SENSORIAL</text>
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                <text>CATA</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2016</text>
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            <name>Abstract</name>
            <description>A summary of the resource.</description>
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                <text>Methodological research is needed to support the continued popularity of sensory product characterization by consumers. The present research considers stability and reliability of such product spaces. Using data from 13 studies (n&amp;thinsp;=&amp;thinsp;1332) involving check-all-that-apply questions (CATA) and projective mapping tasks replicated assessments and increasing the sample size are evaluated for their impact on the product spaces derived from a base group of consumers. In each study, a group of consumers (41&amp;ndash;95 participants) completed a sensory characterization task twice under identical conditions (&amp;ldquo;replication&amp;rdquo; condition), and additional consumers (49&amp;ndash;93 participants) completed the task (&amp;ldquo;increased sample size&amp;rdquo; condition). The stability of product spaces was evaluated using a bootstrapping resampling approach. Both experimental conditions had a small but positive impact as evidenced by small increases in average RV coefficients across simulations. Additionally, in studies using projective mapping, the confidence ellipses around sample positions were smaller than those established in product spaces with the base group of consumers. This pointed to increased sample discrimination.</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="412163">
                <text>&lt;strong&gt;Vidal, Leticia&lt;/strong&gt;</text>
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              <elementText elementTextId="412164">
                <text>&lt;strong&gt;Jaeger, Sara R.&lt;/strong&gt;</text>
              </elementText>
              <elementText elementTextId="412165">
                <text>&lt;strong&gt;Ant&amp;uacute;nez, Luc&amp;iacute;a&lt;/strong&gt;</text>
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              <elementText elementTextId="412166">
                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0d41faa00b2d3f65601f9525c8a720d6" target="_blank"&gt;&lt;strong&gt;Gim&amp;eacute;nez, Ana&lt;/strong&gt;&lt;/a&gt;</text>
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              <elementText elementTextId="412167">
                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=358965ab1701bacbb43e4f5a24a8e876" target="_blank"&gt;&lt;strong&gt;Ares, Gast&amp;oacute;n&lt;/strong&gt;&lt;/a&gt;</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="412168">
                <text>Journal of Sensory Studies&amp;nbsp; v. 31, no. 3, 2016. -- p. 373-381</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="412169">
                <text>Wiley</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="412170">
                <text>2016</text>
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            </elementTextContainer>
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          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="412171">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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              <elementText elementTextId="412172">
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            <name>Language</name>
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            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="412175">
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        <name>CATA</name>
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        <name>Evaluación sensorial</name>
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              <name>Title</name>
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                  <text>Bibliografía Nacional Química</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="709198">
                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                  <text>Departamento de Documentación y Biblioteca</text>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>PDF</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Antimutagenic and antioxidant properties of the aqueous extracts of organic and conventional grapevine Vitis labrusca cv. Isabella leaves in V79 cells&lt;/strong&gt;</text>
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            <name>Subject</name>
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                <text>UVAS</text>
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                <text>ACTIVIDAD ANTIGENOTOXICA</text>
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                <text>ACTIVIDAD ANTIMUTAGENICA</text>
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              <elementText elementTextId="412571">
                <text>VITIS LABRUSCA</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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              <elementText elementTextId="412573">
                <text>2016</text>
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          <element elementId="87">
            <name>Abstract</name>
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                <text>Grapes are one of the most commonly consumed fruit, in both fresh and processed forms; however, a significant amount is disposed of in the environment. Searching for a use of this waste, the antigenotoxic, antimutagenic, and antioxidant activities of aqueous extracts from organic and conventional Vitis labrusca leaves were determined using V79 cells as model. The antigenotoxic activity was analyzed by the alkaline comet assay using endonuclease III and formamidopyrimidine DNA glycosylase enzymes. The antimutagenic property was assessed through the micronucleus (MN) formation, and antioxidant activities were assessed using 2',7'-dichlorodihydrofluorescin diacetate (DCFH-DA) assay and 2,2-diphenyl-1-picrylhydrazyl (DPPH(●)) radical scavenging, as well as with superoxide dismutase (SOD) and catalase (CAT) activity assays. In addition, phenolic content and ascorbic acid levels of both extracts were determined. Data showed that both organic and conventional grapevine leaves extracts possessed antigenotoxic and antimutagenic properties. The extract of organic leaves significantly reduced intracellular reactive oxygen species (ROS) levels in V79 cells, and displayed greater ability for DPPH(●) scavenging and higher SOD and CAT activities than extract from conventional leaves. Further, the extract from organic leaves contained higher phenolic and ascorbic acid concentrations. In summary, extracts from organic and conventional grape leaves induced important in vitro biological effects.</text>
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              <elementText elementTextId="412575">
                <text>&lt;strong&gt;Trindade, Cristiano&lt;/strong&gt;</text>
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              <elementText elementTextId="412576">
                <text>&lt;strong&gt;Vera Bortolini, Giovana&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Segalotto Costa, B&amp;aacute;rbara&lt;/strong&gt;</text>
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              <elementText elementTextId="412578">
                <text>&lt;strong&gt;Carra Anghinoni, Joanna&lt;/strong&gt;</text>
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              <elementText elementTextId="412579">
                <text>&lt;strong&gt;Nikolova Guecheva, Temenouga&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Arias, Ximena&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=0a105db2a5a7c020d6e14e25180d1b21" target="_blank"&gt;&lt;strong&gt;Cesio, Mar&amp;iacute;a Ver&amp;oacute;nica&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Moura, Dinara Jacqueline&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Saffi, Jenifer&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Salvador, Mirian&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;P&amp;ecirc;gas Henriques, Jo&amp;atilde;o Antonio&lt;/strong&gt;</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="412587">
                <text>Journal of Toxicology and Environmental Health part. A&amp;nbsp; v. 79, no. 18, 2016. -- p. 825-836</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="412588">
                <text>Taylor &amp;amp; Francis</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="412589">
                <text>2016</text>
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            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="412590">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Metallo-&amp;beta;-lactamases (MBLs) hydrolyze almost all &amp;beta;-lactam antibiotics and are unaffected by clinically available &amp;beta;-lactamase inhibitors (&amp;beta;LIs). Active-site architecture divides MBLs into three classes (B1, B2, and B3), complicating development of &amp;beta;LIs effective against all enzymes. Bisthiazolidines (BTZs) are carboxylate-containing, bicyclic compounds, considered as penicillin analogs with an additional free thiol. Here, we show both l- and d-BTZ enantiomers are micromolar competitive &amp;beta;LIs of all MBL classes in vitro, with Kis of 6-15 &amp;micro;M or 36-84 &amp;micro;M for subclass B1 MBLs (IMP-1 and BcII, respectively), and 10-12 &amp;micro;M for the B3 enzyme L1. Against the B2 MBL Sfh-I, the l-BTZ enantiomers exhibit 100-fold lower Kis (0.26-0.36 &amp;micro;M) than d-BTZs (26-29 &amp;micro;M). Importantly, cell-based time-kill assays show BTZs restore &amp;beta;-lactam susceptibility of Escherichia coli-producing MBLs (IMP-1, Sfh-1, BcII, and GOB-18) and, significantly, an extensively drug-resistant Stenotrophomonas maltophilia clinical isolate expressing L1. BTZs therefore inhibit the full range of MBLs and potentiate &amp;beta;-lactam activity against producer pathogens. X-ray crystal structures reveal insights into diverse BTZ binding modes, varying with orientation of the carboxylate and thiol moieties. BTZs bind the di-zinc centers of B1 (IMP-1; BcII) and B3 (L1) MBLs via the free thiol, but orient differently depending upon stereochemistry. In contrast, the l-BTZ carboxylate dominates interactions with the monozinc B2 MBL Sfh-I, with the thiol uninvolved. d-BTZ complexes most closely resemble &amp;beta;-lactam binding to B1 MBLs, but feature an unprecedented disruption of the D120-zinc interaction. Cross-class MBL inhibition therefore arises from the unexpected versatility of BTZ binding.</text>
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                <text>Proceeding of the National Academy Sciences of the United States of America v. 113, no. 26, 2016. -- p. E3745-3754</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Steam reforming of crude glycerol, a side product of biodiesel industry, could be used to obtain H2 and H2/ CO mixtures using Ni based catalysts. In this work, carbon supported nickel catalysts prepared by a simple impregnation technique were studied in the crude glycerol steam reforming at 650 �C to yield H2 and CO2 as the main products. Promotion with different metal oxides (MgO, La2O3, Y2O3) is effective to increase H2 yield which attain more than 80% of the maximum theoretical amount with MgO. Rh promotion is also detected at the initial stages of the process although it is counteracted by the deleterious effect of carbon deposits on the active metal. Carbon deposits and sintering of the active metal are the main sources of deactivation.</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Synthesis, solid-state characterization and solution studies of new phytate compounds with Cu(II) and 1,10-phenanthroline: progress in the structural elucidation of phytate coordinating ability&lt;/strong&gt;</text>
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                <text>Within all the eukaryotic cells there is an important group of biomolecules that has been potentially related to signalling functions: myo-inositol phosphates (InsPs). In nature, the most abundant member of this family is the so called phytate (InsP6, L12&amp;minus;). The importance of the interaction of InsP6 with cations has been recognized during the last few years, and any attempt to know the function of this molecule in eukaryotic cells must include the fact that InsP6 will be strongly associated with simple inorganic or organic ammonium cations. In this work we expand on our earlier findings by studying the systems phen&amp;ndash;phytate (phen = 1,10-phenanthroline) and Cu(II)&amp;ndash;phen&amp;ndash;phytate. The structures of (Hphen)4(H8L)&amp;middot;7.5H2O and [Cu5(H7L)2(H2O)2(phen)5]&amp;middot;23H2O are presented. Solution studies of the binary and ternary systems were also performed by means of potentiometric titrations at 37.0 &amp;deg;C and 0.15 M ionic strength. The work was completed with a molecular modelling study. All this information is essential in the process of gaining reliable structural knowledge about the most important InsP6 species in the in vitro and in vivo experiments, and how these features modulate their probable biological functions.</text>
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                <text>&lt;strong&gt;Qui&amp;ntilde;one, D.&lt;/strong&gt;</text>
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                <text>Dalton Transactions v. 45, no. 30, 2016. -- p. 12156-12166</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Bond dissociation energies and enthalpies of formation of flavonoids :&amp;nbsp; A G4 and M06-2X investigation&lt;/strong&gt;</text>
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                <text>By means of G4 theory and M06-2X calculations we investigated the thermochemistry and C&amp;ndash;OH bond ruptures of quercetin, fistein, lutelin, caffeic acid, pinocembrin and p-coumaric acid. Notwithstanding the fact that we observed a good agreement for the prediction of the weakest O&amp;ndash;H bond, the mean absolute deviation (MAD) between the bond dissociation energies (BDE) computed at the G4 and M06-2X/6-311+G(3df,2p) levels was 5.0 kcal/mol. With regard to the &amp;Delta;Hof,0 computed at the M06-2X/6-311+G(3df,2p) level, the MAD was 10.0 kcal/mol. Therefore, thanks to error cancellation the error found for the O&amp;ndash;H BDE was smaller. Intramolecular hydrogen bond is one of the key factors stabilizing the oxygen radicals formed when the CO&amp;ndash;H bonds are broken. Finally, we propose the following enthalpies of formation at 0 K: &amp;minus;222.0, &amp;minus;174.5, &amp;minus;180.2, &amp;minus;134.4, &amp;minus;109.7 and &amp;minus;91.9 kcal/mol for quercetin, fistein, lutelin, caffeic acid, pinocembrin and p-coumaric acid, respectively.</text>
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                <text>Computational and Theoretical Chemistry v. 1091, 2016. -- p. 18-23</text>
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