183 25 6756 https://riquim.fq.edu.uy/files/original/bb5f098f063f58a8d0eb4f349cbd2d67.pdf 00856400ed20b3ff9ad90ff1d68f3dcc https://riquim.fq.edu.uy/files/original/0ce3f6140c7daf4da59da9b3a08d4346.jpg 0aa17788c3027a9cfa99f4ba293a30ad Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 194 Width 148 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands : potential anti-trypanosomal agents Subject The topic of the resource TRIPANOSOMIASIS SINTESIS QUIMICA COMPUESTOS ORGANOMETALICOS BIBLIOGRAFIA NACIONAL QUIMICA 2012 Abstract A summary of the resource. In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasites, and particularly against African Trypanosomiasis, whose etiological agent is Trypanosoma brucei, organoruthenium compounds with bioactive nitrofuran containing thiosemicarbazones (L) as co-ligands were obtained. Four ruthenium(II) complexes with the formula [Ru2(p-cymene)2(L)2]X2, where X = Cl or PF6, were synthesized and the crystal structures of two of them were solved by X-ray diffraction methods. Two of the complexes show significant in vitro growth inhibition activity against Trypanosoma brucei brucei and are highly selective towards trypanosomal cells with respect to mammalian cells (J774 murine macrophages). These promising results make the title organoruthenium compounds good lead candidates for further developments towards potential antitrypanosomal organometallic drugs. Creator An entity primarily responsible for making the resource Demoro, Bruno Sarniguet, Cynthia Sanchez-Delgado, Roberto Rossi, Miriam Liebowitz, Daniel Caruso, Francesco Olea-Azar, Claudio Moreno, Virtudes Medeiros, Andrea Comini, Marcelo <a href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=b2795d82d8f9cb610b167b6577f861a5">Otero Zubiaurre, Ana Lucía</a> Source A related resource from which the described resource is derived Dalton Transactions v. 41, no. 5, 2012. -- p. 1534-1543 Publisher An entity responsible for making the resource available Royal Society of Chemistry Date A point or period of time associated with an event in the lifecycle of the resource 2012 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.   Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1039/c1dt11519g Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant     Antitripanosomas Rutenio https://riquim.fq.edu.uy/files/original/1e5988d37381af4a5e3d5b5472bf8bce.gif 2acf58d9340df17bc258184d2b1cde46 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 150 Width 113 https://riquim.fq.edu.uy/files/original/5cd0563e750489de872a6ea68ef33784.pdf 00856400ed20b3ff9ad90ff1d68f3dcc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New oxidovanadium(IV) N-acylhydrazone complexes :  Promising antileishmanial and antitrypanosomal agents Subject The topic of the resource LEISHMANIASIS ANTITRIPANOSOMAS ENFERMEDAD DE CHAGAS OXIDOVANADIO BIBLIOGRAFIA NACIONAL QUIMICA 2013 Abstract A summary of the resource. Searchingfor newpromisingmetal-based hits against Trypanosoma cruzi andLeishmaniaparasites,two related oxidovanadium(IV) N-acylhydrazone complexes, [VIVO(LASSBio1064-2H)(H2O)], 1, and [VIVO(LASSBio1064- 2H)(phen)]$(H2O), 2, where LASSBio1064¼ (E)-N0-(2-hydroxybenzylidene-4-chlorobenzohydrazide and phen ¼ 1,10-phenanthroline, were synthesized and characterized in the solid state and in solution by elemental analysis, conductimetric measurements and ESI-MS, FTIR, EPR and 51V NMR spectroscopies and were evaluated on T. cruzi and Leishmania major. In addition, their unspecific cytotoxicity was tested against murine macrophages. Furthermore, to provide insight into the possible mechanism of its antiparasitic action, [VO(LASSbio1064-2H)(phen)].(H2O)was tested for its DNA interaction ability on plasmid DNA by atomic force microscopy (AFM) and on CT DNA by using DNAviscosity measurements and fluorescence spectroscopy. Both complexeswere active in vitro against the epimastigote formof T. cruzi (Tulahuen 2 strain) showing IC50 values of the same orderor significantly lower thanthat of the reference trypanosomicidal drug Nifurtimox.However, only the mixed-ligand oxidovanadium(IV) complex 2,which includes phen in its coordination sphere, showed activity on L. major promastigotes with a IC50 value of 22.1 � 0.6 mM. The compounds show low toxicity on mammalian cells (IC50 > 100 mM). DNA interaction studies showed that the mixed-ligand complex is able to interact with this biomolecule probably through an intercalative mode, pointing out at DNA as a potential target in the parasite. The results suggest that [VIVO(LASSBio1064-2H)(phen)]$(H2O) may be a promising compound for further drug development stages Creator An entity primarily responsible for making the resource Benítez, Julio Cavalcanti de Queiroz, Aline Correia, Isabel Amaral Alvez, Marina Alexandre-Moreira, Magna S. Barreiro, Eliezer J. Moreira Lima, Lidia Varela, Javier González, Mercedes Cerecetto, Hugo Moreno, Virtudes Costa Pessoa, João <a title="Currículum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2ff5755f42707a83e7aea75299e5667c" target="_blank">Gambino, Dinorah</a> Source A related resource from which the described resource is derived European Journal of Medicinal Chemistry v. 62C, no. 1, 2013. -- p. 20-27 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2013 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.   Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context http://dx.doi.org/10.1016/j.ejmech.2012.12.036 Antitripanosomas Enfermedad de chagas Oxidovanadio https://riquim.fq.edu.uy/files/original/51683f7e0f6af9a7544e9bbd21204f29.pdf 26eae7e0c2a58a43c61fe0694186c6ec https://riquim.fq.edu.uy/files/original/d9d4986e3a128688559c3cc9ec656733.jpg 2c94c80e179a95f858f303f53a9b0b36 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 155 Width 118 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New Pd–Fe ferrocenyl antiparasitic compounds with bioactive 8-hydroxyquinoline ligands: a comparative study with their Pt–Fe analogues&dagger; Subject The topic of the resource ANTIPARASITARIOS TRYPANOSOMA BRUCEI PARASITOS QUIMIOTERAPIA BIBLIOGRAFIA NACIONAL QUIMICA 2021 Abstract A summary of the resource. In the search for a more effective chemotherapy for the treatment of Human African Trypanosomiasis, a disease caused by the parasite Trypanosoma brucei, the development of ferrocenyl compounds has arisen as a promising strategy. In this work, five new Pd–Fe heterobimetallic [PdII(L)(dppf)](PF6) compounds, including 8-hydroxyquinolyl derivatives HL1–HL5 as bioactive ligands and dppf = 1,1’-bis(diphenylphosphino) ferrocene as the organometallic co-ligand, were synthesized and fully characterized in the solid state and in solution. Molecular structures of three compounds were solved by single crystal X-ray diffraction methods. The compounds displayed submicromolar or micromolar IC50 values against bloodstream T. brucei (IC50: 0.33–1.2 μM), and good selectivity towards the pathogen (SI: 4–102) with respect to mammalian macrophages (cell line J774). The new Pd complexes proved to be 2-fold to 45-fold more potent than the drug nifurtimox but most of them are less active than their Pt analogues. Potential molecular targets were studied. The complexes interact with DNA but they do not alter the intracellular thiolredox homeostasis of the parasite. In order to understand and predict the main structural determinants on the anti-T. brucei activity, a search of quantitative structure–activity relationships (QSAR) was performed including all the [M(L)(dppf)](PF6) complexes, where M = Pd(II) or Pt(II), currently and previously developed by us. The correlation obtained shows the relevance of the electronic effects, the lipophilicity and the type of metal. According to the QSAR study, compounds with electron-withdrawing ligands, higher lipophilicity and harboring Pt would result in higher T. brucei cytotoxicity. From the whole series of [M(L)(dppf)](PF6) compounds developed, where M = Pt(II) or Pd(II) and HL = 8-hydroxyquinolyl derivatives, Pt-dppf-L4 (IC50 = 0.14 μM, SI = 48) was selected to perform an exploratory pre-clinical study in infected mice. This hit compound lacks acute toxicity when applied to animals in the dose/regimen described and exerts an anti-proliferative effect on parasites, which extends animal survival but is not curative. Creator An entity primarily responsible for making the resource Rivas, Feriannys Medeiros, Andrea Quiroga, Cristina Benítez, Diego Comini, Marcelo Rodríguez Arce, Esteban Machado, Ignacio Cerecetto, Hugo Gambino, Dinorah Source A related resource from which the described resource is derived Dalton Transactions, v. 50, n° 5, 2021.-- pp. 1651-1665. Publisher An entity responsible for making the resource available Royal Society of Chemistry Date A point or period of time associated with an event in the lifecycle of the resource 2021 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context 10.1039/d0dt03963b  Antiparasitarios Parásitos Quimioterapia Trypanosoma brucei https://riquim.fq.edu.uy/files/original/ddd18dfbd347fcfe781d50fea7975aab.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/c9d38fab15469ec7821add36e44d8435.jpg 3a9d2edb1a7d580f2dbb27a80c380745 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 192 Width 140 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New perhydro-1,4-oxazine derivatives or arylethanolamine with beta 3-adrenoceptor agonist activity. Subject The topic of the resource OXAZINAS BIBLIOGRAFIA NACIONAL QUIMICA 1995 Creator An entity primarily responsible for making the resource Monge, A Aldana, Ignacio Rivero, A Cerecetto, Hugo Del Barrio, A Perez, R Portillo, M Martínez, A Source A related resource from which the described resource is derived Die Pharmazie v. 50, , 1995. -- p. 768-769 Publisher An entity responsible for making the resource available International Journal of Pharmaceutical Science Date A point or period of time associated with an event in the lifecycle of the resource 1995 Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context ISSN: 0031-7144 Oxazinas https://riquim.fq.edu.uy/files/original/6e2632300bfabaafbccce1fb9fa29919.pdf 947f6d95d50484d4bb1c2c8b0760770f https://riquim.fq.edu.uy/files/original/f7f51c34f54b5df62b0f4fdac4848bb6.jpg f7e7419887ead8c2f0bdf596e7f3670f Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 155 Width 107 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New perspective on thermally stimulated luminescence and crystallization of barium borate oxyfluoride glasses Subject The topic of the resource NANOTECNOLOGIA CRISTALIZACION BORATOS NANOCRISTALES BIBLIOGRAFIA NACIONAL QUIMICA 2021 Abstract A summary of the resource. The demand for modern materials, especially glasses, used in different applications, such as radiation sensors and spectral converters, requires a detailed study of their properties. The incorporation of fluoride compounds in borate glasses and their crystallization at the nanometric scale allows the properties of these materials to be further enhanced. Although many works showed improvements in some of these properties, some critical aspects, such as the crystallization mechanism and the role of the fluorine phase, need more investigation. We worked with xNaF (100 - x)BaO.2B2O3 glasses with x = 0, 5, 10, 15, 20, 25, 30, and 35% (in mol) to increase the knowledge in this field. The structural modifications and the thermally stimulated luminescence of the glasses were studied, and their crystallization was analyzed by thermal analysis and X-ray diffraction. A continuous trap distribution was found, which was responsible for its very good luminescent signal, especially in glasses with 20% NaF. By selecting a suitable amount of NaF, it is possible to obtain nanocrystals of BaF2. These promising results we reached show the applicability of these materials. Creator An entity primarily responsible for making the resource <a href="https://exportcvuy.anii.org.uy/cv/?2d8c17d067a81fe296d9c5c87537945b417ea1cf17629c170cb2dd195328c851975f94975dbaf56319a8ccf2709b6b385f4f06950860ce21c6771e5683aba10b" target="_blank">Rodríguez Chialanza, Mauiricio</a> Azcune, Germán Bentos Pereira, Heinkel <a href="https://exportcvuy.anii.org.uy/cv/?2f2e59581473324400ee29ded741b9090cc25a893e73d02669ebfbc674c9e8b9b51bb30e2bca064dc7ebbd5c39aa3c844e86e507301e912aa1b0a5ae17423fa2" target="_blank">Faccio, Ricardo</a> Source A related resource from which the described resource is derived Crystals v. 11, n° 7, 2021. -- e745. -- pp. 1-15 Publisher An entity responsible for making the resource available MDPI Date A point or period of time associated with an event in the lifecycle of the resource 2021 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos)  La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context 10.3390/cryst11070745 https://riquim.fq.edu.uy/files/original/8ef597cbc44adbc41ea7bb31d4f88b63.pdf c845c1000b6329c094a98acfecd6b7ea https://riquim.fq.edu.uy/files/original/582a23d6fdd20c1fd75ea114fad84eab.jpg a4c6dfc2ff43aab0b78df0f036ee5f3d Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 155 Width 116 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New perspectives into Gluconobacter-catalysed biotransformations Subject The topic of the resource GLUCONOBACTER BIOTRANSFORMACIONES INGENIERIA GENETICA BIOTECNOLOGÍA QUIMICA VERDE BIBLIOGRAFIA NACIONAL QUIMICA 2023 Abstract A summary of the resource. Different from other aerobic microorganisms that oxidise carbon sources to water and carbon dioxide, Gluco nobacter catalyses the incomplete oxidation of various substrates with regio- and stereoselectivity. This ability, as well as its capacity to release the resulting products into the reaction media, place Gluconobacter as a privileged member of a non-model microorganism class that may boost industrial biotechnology. Knowledge of new technologies applied to Gluconobacter has been piling up in recent years. Advancements in its genetic modifi cation, application of immobilisation tools and careful designs of the transformations, have improved pro ductivities and stabilities of Gluconobacter strains or enabled new bioconversions for the production of valuable marketable chemicals. In this work, the latest advancements applied to Gluconobacter-catalysed bio transformations are summarised with a special focus on recent available tools to improve them. From genetic and metabolic engineering to bioreactor design, the most recent works on the topic are analysed in depth to provide a comprehensive resource not only for scientists and technologists working on/with Gluconobacter, but for the general biotechnologist. Creator An entity primarily responsible for making the resource <a href="https://export.cvuy.uy/cv/?d5ee750fdc08379d9c397cbde95bc56f23132e7c7068d129e8477348e6cb1c042064fa4299097e95dfc236377ab66fba1f6aff2e8d116d24eaab7c4cc381aec8" target="_blank">Ripoll, Magdalena</a> Lerma Escalera, Jordy Alexis Morones Ramírez, José Rubén Rios Solis, Leonardo Betancor, Lorena Source A related resource from which the described resource is derived Biotechnology Advances, v.65, 2023. -- e108127 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2023 Rights Information about rights held in and over the resource Different from other aerobic microorganisms that oxidise carbon sources to water and carbon dioxide, Gluco nobacter catalyses the incomplete oxidation of various substrates with regio- and stereoselectivity. This ability, as well as its capacity to release the resulting products into the reaction media, place Gluconobacter as a privileged member of a non-model microorganism class that may boost industrial biotechnology. Knowledge of new technologies applied to Gluconobacter has been piling up in recent years. Advancements in its genetic modifi cation, application of immobilisation tools and careful designs of the transformations, have improved pro ductivities and stabilities of Gluconobacter strains or enabled new bioconversions for the production of valuable marketable chemicals. In this work, the latest advancements applied to Gluconobacter-catalysed bio transformations are summarised with a special focus on recent available tools to improve them. From genetic and metabolic engineering to bioreactor design, the most recent works on the topic are analysed in depth to provide a comprehensive resource not only for scientists and technologists working on/with Gluconobacter, but for the general biotechnologist. Format The file format, physical medium, or dimensions of the resource PDF Extent The size or duration of the resource. 26 p. Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context 10.1016/j.biotechadv.2023.108127 Biotecnología Biotransformaciones Gluconobacter Ingeniería Genética Química verde https://riquim.fq.edu.uy/files/original/c910bc083c41a8d03c1846bfdfe7d6b5.pdf 0ebebc2e46cd599f97051dd7aefd7031 https://riquim.fq.edu.uy/files/original/81c33c66f6584d02b1efbb9c92f1d57d.jpg 2d04bd06699a2e5d7fab5cbf36ebe717 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 272 Width 200 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New polynuclear compounds based on N-benzyliminodipropionic acid : |b solution studies, synthesis, and X-ray crystal structures Subject The topic of the resource RAYOS X COMPUESTOS POLINUCLEARES SINTESIS QUIMICA ESTRUCTURA CRISTALINA BIBLIOGRAFIA NACIONAL QUIMICA 2016 Abstract A summary of the resource. Three new polynuclear compounds based on a dicarboxylic acid ligand are reported. In particular, two Cu(II) coordination compounds, [Cu2(H2O)6(Hbzlidp)2](CF3SO3)2·2H2O (1) and [Cu(NO3)(Hbzlidp)]∞ (2) (bzlidp2− = N-benzyliminodipropionate anion), and a Ni(II) dinuclear compound, [Ni2(H2O)4(bzlidp)2] (3), were synthesized and characterized by IR spectroscopy, elemental analysis and single crystal X-ray diffraction. Different structures were obtained depending on the reaction conditions. The structural analyses reveal that 1 was formed by dinuclear [Cu2(H2O)6(Hbzlidp)2]2+ units built by two copper(II) ions joined through two Hbzlidp− ligands, while 2 was formed by pairs of Cu(II) centers bridged by four syn,syn carboxylate groups to generate “paddle wheel” units. The dinuclear copper units are arranged in a rhombus type grid, in a 2-D layer structure. In both cases, the N was protonated and not coordinated to the metal center. Compound 3 was formed by [Ni2(H2O)4(bzlidp)2] neutral dinuclear units, with octahedral Ni(II) centers. Solution studies of the ligand–M(II) systems (M(II) = Mn, Co, Ni, Cu, Zn, Cd, and Pb) were also carried out. Creator An entity primarily responsible for making the resource Braña, Emiliano Quiñone, Delfina Martínez, Sebastián Grassi, Joaquín Carrera, Ignacio <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=b1b8a8c8b1a5835b874ac1994003c38d" target="_blank">Torres, Julia</a> González-Platas, Javier <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=502f70a0642a910f5abf0e0d5c853b61" target="_blank">Seoane, Gustavo</a> <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=6f16399c452f7b13f8a01a148cb38e12" target="_blank">Kremer, Carlos</a> Mendoza, Carolina Source A related resource from which the described resource is derived Journal of Coordination Chemistry  v. 69, no. 24, 2016. -- p. 3650-3663 Publisher An entity responsible for making the resource available Taylor & Francis Date A point or period of time associated with an event in the lifecycle of the resource 2016 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1080/00958972.2016.1239086 Compuestos polinucleares Estructura cristalina Rayos X Síntesis Química https://riquim.fq.edu.uy/files/original/60bef9ef0c9a080cb1c7438dd3cd0047.pdf c845c1000b6329c094a98acfecd6b7ea https://riquim.fq.edu.uy/files/original/74c7d84a8953713856ce95e7679a0074.jpg b99eacbbf3c1159112d10f00bfc7e8d9 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 155 Width 116 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New polynuclear compounds based on N-methyliminodipropionic acid: solution studies, synthesis and X-ray crystal structures Subject The topic of the resource COMPLEJOS POLINUCLEARES METALES DE TRANSICION BIBLIOGRAFIA NACIONAL QUIMICA 2024 Abstract A summary of the resource. Six new polynuclear coordination compounds based on 3d transition metal ions (Cu(II), Ni(II)) and Zn(II) with the flexible dicarboxylate compound N-methyliminodipropionic acid (H2midp) were prepared and characterized by IR spectroscopy, elemental analysis and single-crystal X-ray diffraction. Four of these compounds are 1D coordination polymers, namely [Cu(midp)(H2O)] (1), [Cu3(midp)2(H2O)4](NO3)2⋅6H2O (2) [Cu3(midp)2(H2O)4] (CF3SO3)2⋅4H2O (3) and [NaZn(Hmidp)2](CF3SO3) (6). The structural analysis revealed that the chain structure of 1 is composed of [Cu(midp)(H2O)] units connected by the free carboxylato oxygen atom of neighbor units, in an alternate fashion. In 2 and 3, on the other hand, there are two [Cu(midp)H2O] units, connected by a central Cu(II) ion coordinating again to the free oxygen atom of the carboxylato groups. The Zn(II) compound is heteronuclear and the complex adopts a 1D cationic polymeric structure with zinc and sodium ions connected by two Hmidp– anions. The two other compounds are dinuclear, [Cu2(Hmidp)2(μ-H2O)2(H2O)2](CF3SO3)2⋅6H2O (4) and ([Ni2(midp)2(H2O)4] (5). Additionally, a Co(II) and a Cu(II) coordination compound were obtained with the same ligand and characterized by IR spectroscopy, thermal analysis and elemental analysis including metal quantification. For the copper compound the formula [Cu(Hmidp)](ClO4)⋅3H2O (7) is proposed while for the Co (II) compound (8) the proposed formula is [Co(midp)(H2O)2]. Solution studies of the ligand–M(II) systems (M (II) = Mn, Fe, Co, Ni, Cu, Zn, Cd and Pb) were also carried out in order to help the selection of the best synthetic conditions and also to complement the structural knowledge in the exploration of the potential formation of coordination polymers in these systems. Creator An entity primarily responsible for making the resource Cuadrado, Maite Martínez, Sebastián Quiñone, Delfina Torres, Julia González Platas, Javier Kremer, Carlos Mendoza, Carolina Source A related resource from which the described resource is derived Inorganica Chimica Acta v. 569, 2024. -- e122149 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2024 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Extent The size or duration of the resource. 12 p. Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context 10.1016/j.jfp.2024.100286 Complejos polinucleares Metales de transición https://riquim.fq.edu.uy/files/original/2f255b34371e5ae8a840a4995e22a0aa.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/660a97daecdf795e2254f7003aa347ca.jpg d5a9f2c142ae58056d88727126daa0b2 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 201 Width 148 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New potent 5 substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth : quantitative structure activity relationship studies. Subject The topic of the resource TRIPANOSOMA CRUZI BIBLIOGRAFÍA NACIONAL QUÍMICA 2005 Abstract A summary of the resource. Benzofuroxan derivatives have been shown to inhibit the growth of Trypanosoma cruzi, the etiological agent of Chagas� disease. Therefore, 2D- and 3D-QSAR models of their in vitro antichagasic activity were developed. Six new derivatives were synthesized to complete a final set of 26 structurally diverse benzofuroxans. The 2D-QSAR model (r = 0.939, r2 adj ¼ 0:849) was generated using multiple regression analysis of tabulated substituents� physicochemical properties and indicator variables. In addition, a 3D-QSAR model (r2 = 0.997, q2 = 0.802) was obtained using a comparative molecular field analysis (CoMFA). Due to the wellknown benzofuroxan tautomerism, in both approaches (2D- and 3D-QSAR) it was necessary to include an indicator variable to consider the N-oxide position (I6). This parameter was established using low-temperature NMR experiments. Both QSAR models identified the electrophilic character of the substituent a-atom as a requirement for activity. Further support was found using a density functional theory (DFT) approach. Creator An entity primarily responsible for making the resource Aguirre, Gabriela Boiani Santurio, Lucía Boiani Santurio, Mariana Cerecetto, Hugo Di Maio, Rossanna González, Mercedes <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=01ded1b48a793797e49a8cb9b67aecea">Porcal, Williams</a> Denicola Creci, Ana Beatriz Piro, Oscar E Castellano, Eduardo E SantïAnna, Carlos Mauricio E Barreiro, Eliezer J Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2005 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context doi:10.1016/j.bmc.2005.07.072 Trypanosoma cruzi https://riquim.fq.edu.uy/files/original/11488c96e216a1843ce50527bbcfb77c.doc 0f4e6b73dad25df0b61ca80a92a78d89 https://riquim.fq.edu.uy/files/original/2f0a72f55dbad65aa920be462a78f20b.gif 088ef1bc2d2065f2805074a423d4a906 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 150 Width 116 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New potent 5-nitrofuryl derivatives as inhibitors of Trypanosoma cruzi growth. 3d-QSAR (COMFA) studies Subject The topic of the resource TRYPANOSOMA CRUZI 5-NITROFURIL-COMPUESTOS 2006 BIBLIOGRAFÍA NACIONAL QUÍMICA Creator An entity primarily responsible for making the resource Aguirre, Gabriela Boiani Santurio, Mariana Cabrera, Eliana Cerecetto, Hugo Di Maio, Rossanna González, Mercedes. Denicola Creci, Ana Beatriz Sant´Anna, Carlos Mauricio R Barreiro, Eliezer J Source A related resource from which the described resource is derived European Journal of Medicinal Chemistry v. 41, no. 4, 2006. -- p. 457-466 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2006 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1016/j.ejmech.2005.11.008 5-Nitrofuril-Compuestos Trypanosoma https://riquim.fq.edu.uy/files/original/14fdb810cd43af9679df5b34b1e03e87.pdf 0ebebc2e46cd599f97051dd7aefd7031 https://riquim.fq.edu.uy/files/original/6879f58759d04869d27a524472c7c076.bmp 6962b185f0537a05815a281c51d8b797 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: Synthesis, biological evaluation, and mechanism of action studies Subject The topic of the resource ANTITRIPANOSOMAS TRYPANOSOMA CRUZI ENFERMEDAD DE CHAGAS BIBLIOGRAFIA NACIONAL QUÍMICA 2009 Abstract A summary of the resource. New 5-nitroindazole derivatives were developed and their antichagasic properties studied. Eight compounds (14–18, 20, 26 and 28) displayed remarkable in vitro activities against Trypanosoma cruzi (T. cruzi). Its unspecific cytotoxicity against macrophages was evaluated being not toxic at a concentration at least twice that of T. cruzi IC50, for some derivatives. The electrochemical studies, parasite respiration studies and ESR experiment showed that 5-nitroindazole derivatives not be able to yield a redox cycling with molecular oxygen such as occurs with nifurtimox (Nfx). The study on the mechanism of action proves to be related to the production of reduced species of the nitro moiety similar to that observed with benznidazole. Creator An entity primarily responsible for making the resource Rodríguez, Jorge Arán, Vicente J Boiani Santurio, Lucía. Olea-Azar, Claudio Lavaggi Destro, María Laura González, Mercedes Cerecetto, Hugo Maya, Juan Diego Carrasco-Pozo, Catalina Speisky, Hernán Source A related resource from which the described resource is derived Bioorganic and Medicinal Chemistry v.17, no. 24, 2009. -- p.8186-8196 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2009 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingles Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI:10.1016/j.bmc.2009.10.030 Antitripanosomas Enfermedad de chagas Trypanosoma cruzi https://riquim.fq.edu.uy/files/original/277869852007759fb394f266ac4dbb88.pdf 00856400ed20b3ff9ad90ff1d68f3dcc https://riquim.fq.edu.uy/files/original/c0a6864cfe4e036ea1acd15c447fb740.gif 021156383c336381f69a8abfdec81761 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 150 Width 111 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New potent imidazoisoquinolinone derivatives as anti-Trypanosoma Cruzi agents : Biological evaluation and structure-activity relationships Subject The topic of the resource TRYPANOSOMIASIS TRYPANOSOMA CRUZI BIBLIOGRAFIA NACIONAL QUÍMICA 2009 Abstract A summary of the resource. A series of novel benzoimidazo and N-aryl-5-oxo-imidazo[1,2-b]isoquinoline-10-carbothioamides was developed. All the compounds were evaluated for their in vitro action against the epimastigote form of Trypanosoma cruzi. Four of them showed higher activity than Nifurtimox. Their unspecific cytotoxicity was evaluated using HeLa and L6 cells, being non-toxic at concentrations at least 15 and 200 times higher than that of T. cruzi IC50. To gain insight into the mechanism of action, their DNA binding properties and reactivity with glutathione were studied, and QSAR study was performed Creator An entity primarily responsible for making the resource Bollini, Mariela Casal, Juan José Alvarez, Diego E. Boiani Santurio, Lucía González, Mercedes. Cerecetto, Hugo Bruno, Ana María Source A related resource from which the described resource is derived Bioorganic and Medicinal Chemistry |g v.17, 2009. -- p.1437-1444 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2009 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingles Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI:10.1016/j.bbr.2011.03.031 Tripanosomiasis Trypanosoma cruzi https://riquim.fq.edu.uy/files/original/a40fdb8f397f292a3558490db19b01b5.pdf 31f88cbc975a279bd7f983434fdd141b https://riquim.fq.edu.uy/files/original/091b603fa098fbeed5fdfcc46f3ec5a8.jpg fb07edb0c33d1c15cea19eed0c862902 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 136 Width 369 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New potential eukaryotic substrates of the mycobacterial protein tyrosine phosphatase PtpA : hints of a bacterial modulation of macrophage bioenergetics state Subject The topic of the resource TUBERCULOSIS BACTERIAS BIBLIOGRAFIA NACIONAL QUIMICA 2015 Abstract A summary of the resource. The bacterial protein tyrosine phosphatase PtpA is a key virulence factor released by Mycobacterium tuberculosis in the cytosol of infected macrophages. So far only two unrelated macrophage components (VPS33B, GSK3a) have been identified as PtpA substrates. As tyrosine phosphatases are capable of using multiple substrates, we developed an improved methodology to pull down novel PtpA substrates from an enriched P-Y macrophage extract using the mutant PtpA D126A. This methodology reduced non-specific protein interactions allowing the identification of four novel putative PtpA substrates by MALDI-TOF-MS and nano LC-MS: three mitochondrial proteins - the trifunctional enzyme (TFP), the ATP synthase, and the sulfide quinone oxidoreductase - and the cytosolic 6-phosphofructokinase. All these proteins play a relevant role in cell energy metabolism. Using surface plasmon resonance, PtpA was found to bind immunopurified human TFP through its catalytic site since TFP-PtpA association was inhibited by a specific phosphatase inhibitor. Moreover, PtpA wt was capable of dephosphorylating immunopurified human TFP in vitro supporting that TFP may be a bona fide PtpA susbtrate. Overall, these results suggest a novel scenario where PtpA-mediated dephosphorylation may affect pathways involved in cell energy metabolism, particularly the beta oxidation of fatty acids through modulation of TFP activity and/or cell distribution. Creator An entity primarily responsible for making the resource Margenat, Mariana Labandera, Anne-Marie Gil, Magdalena Carrion, Federico Purificaçao, Marcela Razzera, Guilherme Portela, María Magdalena Obal, Gonzalo Terenzi, Hernan Pritsch , Otto Durán, Rosario Ferreira, Ana María Villarino, Andrea Source A related resource from which the described resource is derived Scientific Reports no. 5, 2015.-- e 8819 Publisher An entity responsible for making the resource available Nature Date A point or period of time associated with an event in the lifecycle of the resource 2015 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.   Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1038/srep08819 Bacterias Tuberculosis https://riquim.fq.edu.uy/files/original/3eca762342d520d5034861befcff9396.pdf c845c1000b6329c094a98acfecd6b7ea https://riquim.fq.edu.uy/files/original/c254799ebe17c508f0cb58dc9a521ec0.jpg bebbbd72409e932841b426fd4fa38e16 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 155 Width 115 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New preparation protocols for coumarin-thiosemicarbazone hybrids: solid state characterization, and in silico /NMR studies of the Z/E isomerization equilibria in solution Subject The topic of the resource CALCULOS DFT CRISTALOGRAFIA MICROONDAS REACTORES BIBLIOGRAFIA NACIONAL QUIMICA 2022 Abstract A summary of the resource. a b s t r a c t In this work, two improved experimental protocols for the preparation of eight coumarin- thiosemicarbazone hybrids are described. The novel methodologies, based on the use of a microwave- assisted protocol (MW) or a sealed vessel conventionally heated reactor (SVR) are faster, more efficient and render higher yields (average increase in yield = 11% and 16%, respectively). For the solid state char- acterization, infrared spectra of the obtained compounds were analyzed with the aid of computational tools for signal assignation. In addition, a new crystal structure for the E isomer of compound 2d was obtained and a thorough analysis of the intra and intermolecular interactions was performed by Hir- shfeld surface analysis. On the other hand, the hybrids were characterized in DMSO-d 6 solution by 1 H and 13 C NMR experiments. All of them showed a set of minor signals neither ascribable to the products nor described in the literature. Variable temperature 1 H NMR experiments revealed that a single inter- conversion equilibrium was operative in the solution, having thermodynamic parameters compatible to those predicted for a Z/E isomerization process by a DFT model. The most stable configuration ( E ) was further confirmed by DFT, calculating the 13 C NMR chemical shifts for both configurations. The compu- tational model shows that the E configuration is stabilized through the formation of a non-conventional C-H ···O = C intramolecular H-bond between the methyl and carbonyl groups, adopting a conformation less sterically strained. These findings allow to gain insights into the E / Z isomerization equilibria displayed by thiosemicarbazones in solution, a phenomenon usually under described in literature, which seems to be promoted by a balance between weak intramolecular interactions that modulate the relative isomeric stability in solution. Creator An entity primarily responsible for making the resource <a href="https://exportcvuy.anii.org.uy/cv/?e32132aae545e11dc7702ae3ec5eea7e77f167f3796cd5f1e7d13114951802fd64115b8074d6dcd7a7876e39e09d96c7762604944a556dd5d868e93ba33c7eaa" target="_blank">Rostán, Santiago</a> <a href="https://exportcvuy.anii.org.uy/cv/?e635b6babb330f7d853c44bebf28147f45249ebe02a83f148a2cc7d1d4cfc6eb7c052c905498e0db71ce84c545c5bc262c0c1fa15dd485e385d82024819cf422" target="_blank">Alvarez, Natalia</a> <a href="https://exportcvuy.anii.org.uy/cv/?5ad3267f4b4cb5190a6d9a3f5877923f528b6603e8a436c2005a31c5f35cd644629532a16ae958823cff6464fe03287baebd3b8724cc14f8d05da74957fe496d" target="_blank">Veiga, Nicolás</a> <a href="https://exportcvuy.anii.org.uy/cv/?6b87f435587181c154f1b47d1513697ca8585628b36ae67a82085df0df26bef79633f2f87a71609bd85aecc6c98033ecbdad25a883bb2c05df2b6f7a4bfd51d7" target="_blank">Otero, Lucía</a> <a href="https://exportcvuy.anii.org.uy/cv/?11f116dbdcd0917430c764781820c3ae07133f652f4972256dc46f54fda1a3fcf8ce8ef0955ba2079acd7eb19d1ee52d88035eacfdec3666f5e20b2b35381b70" target="_blank">Mahler, G.</a> Source A related resource from which the described resource is derived Journal of Molecular Structure v. 1251, 2022. -- e131980 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2022 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA: La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context 10.1016/j.molstruc.2021.131980 Cálculos DFT Cristalografía Microondas Reactores https://riquim.fq.edu.uy/files/original/59a6bbaa836a732a760a0c22a1567585.pdf aa237209b34f219e3ac3708058f455fc https://riquim.fq.edu.uy/files/original/5c736771b8c6a5a7478f5a88ad2e8da9.png 056a097dbac0babac1983ad7549b1513 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Height 155 Width 155 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New radioactive tracers in the form of coordination complexes for tumor diagnosis. Final report for the period 1 February 1978-28 February 1981 Subject The topic of the resource RADIOQUIMICA NEOPLASMAS DIAGNOSTICO COMPLEJOS ACIDO GLUTAMICO HIGADO RADIOFARMACOS BIBLIOGRAFIA NACIONAL QUIMICA 1981 Creator An entity primarily responsible for making the resource Campos de Kremer, Estrella Source A related resource from which the described resource is derived Technical Report Viena : IAEA, 1981.  52p. Publisher An entity responsible for making the resource available IAEA Date A point or period of time associated with an event in the lifecycle of the resource 1981 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derechode autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA: La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Español Type The nature or genre of the resource Reporte Identifier An unambiguous reference to the resource within a given context ISSN:92-0-125281-1 Acido glutamico Complejos Hígado Neoplasma Radiofármacos Radioquímica https://riquim.fq.edu.uy/files/original/7520d24647b46a2286c9d020952d91c9.pdf 00856400ed20b3ff9ad90ff1d68f3dcc https://riquim.fq.edu.uy/files/original/c6fa2486cc40dc936b13dd076801c49e.jpg eac1b5b30d2408fd546c09ba5eed1226 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 181 Width 140 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New Re V Nitrofuryl Semicarbazone complexes. Crystal structure of ReOCL2(PPh3)(3-(5-Nitrofuryl)acroleine semicarbazone Subject The topic of the resource COMPLEJOS SEMICARBAZONAS BIBLIOGRAFIA NACIONAL QUIMICA Abstract A summary of the resource. The synthesis and characterization of the first two Re complexes with semicarbazone ligands is presented. Selected ligands are 5-Nitro-2-furaldehyde semicarbazone (Nitrofurazone) (L1) and its derivative 3-(5-Nitrofuryl)acroleine semicarbazone (L2). Complexes of general formula [ReVOCl2(PPh3)L], where L � L1 and L2, were prepared in good yields and high purity by reaction of [ReVOCl3(PPh3)2] with L in ethanol or methanol solutions. The complexes formula and molecular structures were supported by elemental analyses and electronic, FTIR, 1H, 13C and 31P NMR spectroscopies. In addition, the crystal and molecular structure of [ReVOCl2(PPh3)L2] was determined by X-ray diffraction methods. [ReOCl2(PPh3)(3-(5-Nitrofuryl)acroleine semicarbazone)] crystallizes in the space group P-1 with a � 11.2334(2), b � 11.3040(2), c � 12.5040(2) A ° , α � 81.861(1), β � 63.555(1), γ � 83.626(1)°, and Z � 2. The Re(V) ion is in a distorted octahedral environment, equatorially coordinated to a deprotonated semicarbazone molecule acting as a bidentate ligand through its carbonylic oxygen and azomethynic nitrogen atoms, to an oxo ligand and a chlorine atom. The six-fold coordination is completed by another chlorine atom and a triphenylphosphine ligand at the axial positions. Creator An entity primarily responsible for making the resource <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=b2795d82d8f9cb610b167b6577f861a5">Otero Zubiaurre, Ana Lucía</a> Castellano, E. Cerecetto, Hugo. <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2ff5755f42707a83e7aea75299e5667c">Gambino, D.</a> Gonzalez,M. Noblia, P. Piro, O.E. Sanchez Delgado, R. Source A related resource from which the described resource is derived Zeitschrift fuer Anorganische und Allgemeine Chemie  v. 629, no. 6, 2003. -- p. 1033-1038 Publisher An entity responsible for making the resource available WILEY-VCH Verlag GmbH & Co. Date A point or period of time associated with an event in the lifecycle of the resource 2003 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1002/zaac.200300012 Complejos Semicarbazonas https://riquim.fq.edu.uy/files/original/68551e0c6a9accc8d4e099da03079455.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/f714fb4b693ff1b05c13e9f2cce6cded.gif fc76ba7ac37250b149175f2d0b6d1bab Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 150 Width 111 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New Re(III) complexes with alkylthioureas as percursors to other Re(III) compounds. Crystal structures of [Re(N-ethylthiourea)6](PF6)3. Subject The topic of the resource RENIO ALQUILTIOUREAS COMPLEJOS BIBLIOGRAFIA NACIONAL QUIMICA 1999 Creator An entity primarily responsible for making the resource <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2ff5755f42707a83e7aea75299e5667c">Gambino, Dinorah</a> Benítez, J <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=b2795d82d8f9cb610b167b6577f861a5">Otero Zubiaurre, Ana Lucía</a> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=37cace18c8d1da50d33d6bd4f8f1a607">Kremer, Eduardo</a> Baran, E. J Piro, O.E Source A related resource from which the described resource is derived Polyhedron v. 18, , 1999. -- p. 2099-2107 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 1999 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1016/S0277-5387(99)00096-0 Alquiltioureas Complejos Renio https://riquim.fq.edu.uy/files/original/570f11ea517c0bf0b5e1ecf3b8ec7f53.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/9697c0da98a2e162015441ab7d9e4e61.JPG 3732cbc74044f8c507a2ef586a8173ac Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 295 Width 237 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New response in electrochemical impedance spectroscopy due to the presence of molybdenum on AB5-type alloys Subject The topic of the resource METALES MOLIBDENO BATERIAS BIBLIOGRAFIA NACIONAL QUIMICA 2015 Creator An entity primarily responsible for making the resource Díaz, Verónica Humana, Rita Teliz, Erika Ruiz, Fabricio Castro, Elida <a title="Currículum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=fc7cd71892b1a9968ee19230dafdbd01" target="_blank">Faccio, Ricardo</a> Zinola Sánchez, Carlos Fernando Source A related resource from which the described resource is derived International Journal o f Hydrogen Energy v. 40, 2015. -- p. 6639-6646 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2015 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context http://dx.doi.org/10.1016/j.ijhydene.2015.03.112 Baterías Metales Molibdeno https://riquim.fq.edu.uy/files/original/d42e00b46c086f09b866726160476c36.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/8e498f9f4d61866e1ac48182221f6958.gif 74e1d833f302ce21035837e95032174b Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 154 Width 115 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New sesquiterpene derivatives from the red alga Laurencia scoparia. Isolation structure determination and anthelmintic activity. Subject The topic of the resource ANTIPARASITARIOS ALGAS LAURENCIA SCOPARIA BIBLIOGRAFIA NACIONAL QUIMICA 2001 Abstract A summary of the resource. Eleven sesquiterpenes (1−11) and one long chain aldehyde (12) have been isolated from the dichloromethane extract of the red alga Laurencia scoparia. Four of them are new natural products. Scopariol (1) is a new natural product with an unusual rearranged chamigrane-type structure. The other three are β-chamigrenes:  isorigidol (2), (+)-3-(Z)-bromomethylidene-10β-bromo-β-chamigrene (3), and (−)-3-(E)-bromomethylidene-10β-bromo-β-chamigrene (4). The in vitro activity of compounds 1−12 against the parasitant stage of Nippostrongylus brasiliensis (L4) has been studied. Creator An entity primarily responsible for making the resource <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=41d9b21783a8c464d1472e49a69c8f69">Davyt, Danilo</a> Fernandez, R <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=8b1a957170f0b5988597d2cc3d6f732b">Suescun, Leopoldo</a> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=31ed37f6d0196c1ca18c1b4dfab6de76">Mombrú Rodríguez, Alvaro Washington</a> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=1adf3c6818ae9c0ff60309b22359778f"> Saldana, J</a> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=ae579f47d769d2ed742a6a34064041f6">Domínguez, Laura</a> Coll, J Fujii, M. T <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=4be67895997a04bff5e21d32915751e0">Manta, Eduardo</a> Source A related resource from which the described resource is derived Journal of Natural Products v. 64, no. 12, 2001. -- p. 1552-5 Publisher An entity responsible for making the resource available American Chemical Society and American Society of Pharmacognosy Date A point or period of time associated with an event in the lifecycle of the resource 2001 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1021/np0102307 Algas Antiparasitarios Laurencia scoparia https://riquim.fq.edu.uy/files/original/9e67ce42c54c2747402025648ca0857f.pdf c845c1000b6329c094a98acfecd6b7ea https://riquim.fq.edu.uy/files/original/5607c84e173fda9b526249803bb9dab2.jpg 99e044660963e137d35c633c77805c90 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 155 Width 116 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New silver(I) phosphino complexes : evaluation of their potential as prospective agents against Mycobacterium tuberculosis Subject The topic of the resource PLATA TUBERCULOSIS FARMACOS BIBLIOGRAFIA NACIONAL QUIMICA 2022 Abstract A summary of the resource. Despite being a preventable and curable disease, Tuberculosis (TB) is the world's top infectious killer. Development of new drugs is urgently needed. In this work, the synthesis and characterization of new silver(I) complexes, that include N′ -[(E)-(pyridine-2-ylmethylene)pyrazine-2-carbohydrazide, HPCPH, as main ligand and substituted aryl-phosphines as auxiliary ligands, is reported. HPCPH was synthesized from pyrazinoic acid, the active metabolite of the first-line antimycobacterial drug pyrazinamide. Complexes [Ag(HPCPH)(PPh3)2]OTf (1), [Ag(HPCPH)((P(p-tolyl)3)2]OTf (2) and [Ag(HPCPH)(P(p-anisyl)3)2]OTf (3) were characterized in solid state and in solution by elemental analysis and FTIR and NMR spectroscopies (OTf––triflate). Crystal structures of (1,2) were determined by XRD. The Ag atom is coordinated to azomethine and pyridine nitrogen atoms of HPCPH ligand and to the phosphorous atom of each aryl-phosphine co-ligand. Although HPCPH did not show activity, the Ag(I) compounds demonstrated activity against Mycobacterium tuberculosis (MTB), H37Rv strain, and multidrug resistant clinical isolates (MDR-TB). Globally, results showed that the compounds are not only effective against the sensitive strain, but are more potent against MDR-TB than antimycobacterial drugs used in therapy. The compounds showed low to moderate selectivity index values (SI) towards the bacteria, using MRC-5 cells (ATCC CCL-171) as mammalian cell model. Interaction with DNA was explored to get insight into the potential mechanism of action against the pathogen. No significant interaction was detected, allowing to discard this biomolecule as a potential molecular target. Compound 1 was identified as a hit compound (MIC90 2.23 μM; SI 4.4) to develop further chemical modifications in the search for new drugs. Creator An entity primarily responsible for making the resource Maldonado, Yndira Dolores <a href="https://exportcvuy.anii.org.uy/cv/?30f70e9dfd00c43ffab403face2bbb4fd0f8853410743d6fa48798782e4078d5bf0735c77ca026b5828f7194ff3401bbfd4bd422c0ea61fda7a3ceb0a5af09f8" target="_blank">Scalese, Gonzalo</a> Manieri, Karyn Fernanda Pavan, Fernando R. Aguirre Méndez, Larry D. <a href="https://exportcvuy.anii.org.uy/cv/?6bb5dcce3e2559101357796ca4a2b2d4c9ba6b3a978a0bd4c5dab0107081b73e1ff46dcf49a7de2b571ff7980c4a01789f09f1d7eac1b879a8553641f940b9a5" target="_blank">Gambino, Dinorah</a> Source A related resource from which the described resource is derived Journal of Inorganic Biochemistry v. 227, 2022. -- e111683 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2022 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA: La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context 10.1016/j.jinorgbio.2021.111683 Fármacos Plata Tuberculosis https://riquim.fq.edu.uy/files/original/56a1252aa70d5951cdc46a15ff9cd235.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/c31059c952796e203da241cf87365c7d.jpg 8035427299b1212b113dc2f86051a05c Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 228 Width 171 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New synthetic approach for the preparation of imidazole N3-oxide. Subject The topic of the resource SINTESIS ORGANICA IMIDAZOL BIBLIOGRAFIA NACIONAL QUIMICA 2004 Abstract A summary of the resource. A new synthetic procedure of 1-alkyl(aryl)-1H-4-methylimidazole N 3-oxide derivatives by cyclocondensation of α-amineoximes and orthoesters was studied. Low yields in the cyclization process were the result of predominant Z-stereoisomer around the oxime moiety of α-amineoxime reactants. Different attempts to improve these yields were assayed, mild conditions being those that produce the best results. Also, the special acidity of hydrogen-2 in the imidazole N 3-oxide system was studied in solution by NMR spectroscopy. This property provides a convenient intermediate to access 2-substituted analogues. Creator An entity primarily responsible for making the resource Cerecetto, Hugo Gerpe, Alejandra González, Mercedes. Fernández Sainz, Yolanda Piro, Oscar E Castellano, E Source A related resource from which the described resource is derived Synthesis no. 16, 2004. -- p. 2678-2684 Publisher An entity responsible for making the resource available Thieme Date A point or period of time associated with an event in the lifecycle of the resource 2004 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.1055/s-2004-831212 Imidazol Síntesis orgánica https://riquim.fq.edu.uy/files/original/a6c5eacb7af057bf0bcea3cc6431ae07.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/f9cf482ba141aa498008ae29eb33bf71.bmp 3d3c998a6eb3ba4439dc297ac8d0d719 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New synthetic route for selectively substituted 1,n-diamines. Synthesis of N-aryl tetra-and pentamethylenediamines. Subject The topic of the resource METODOS DE SINTESIS PRODUCTOS QUIMICOS ORGANICOS SINTESIS QUIMICA DIAMINAS BIBLIOGRAFIA NACIONAL QUIMICA 2010 Abstract A summary of the resource. A general procedure for the synthesis of N-aryltetra- and pentamethylenediamines 1 by acid hydrolysis of N-aryl-N’-acylalkylenediamines 2 under microwave irradiation is described. The precursors 2 are obtained by amination of the corresponding N-(x-haloalkyl)benzamides with aromatic amines 3. Creator An entity primarily responsible for making the resource Ramírez, María A. Corona, María V. Blanco, María M. Perillo, Isabel A. <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=01ded1b48a793797e49a8cb9b67aecea">Porcal, Williams</a> Salerno, Alejandra Source A related resource from which the described resource is derived Tetrahedron Letters v.51, no. 38, 2010. -- p. 5000-5002 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2010 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context doi:10.1016/j.tetlet.2010.07.075 Diaminas Métodos de síntesis Productos químicos orgánicos Síntesis Química https://riquim.fq.edu.uy/files/original/2bda919d75930aa443ba391ac4831a3f.pdf b7a0efe197b424b54b35db6564939425 https://riquim.fq.edu.uy/files/original/722103b3d51a062b9ec5e4badd54366a.GIF 7869724168d299d24166928b146af5b0 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 142 Width 100 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New thiadizine derivatives with activity against Trypanosoma cruzi amastigotes. Subject The topic of the resource TRIPANOSOMA CRUZI BIBLIOGRAFIA NACIONAL QUIMICA 2001 Abstract A summary of the resource. The cytotoxicity of 18 new 1,2,6-thiadiazin-3,5-dione 1,1-dioxides was evaluated. This group of products was previously assayed agai nst epimastigotes of Trypanosoma cruzi and some of them showed a high antiprotozoal activity. Thereafter 13 compounds with a high anti-ep imastigote activity and low cytotoxicity were selected to be assayed against amastigotes. Some of the products showed the same or even lo wer cytotoxicity than nifurtimox and benznidazole, but most of them were very toxic for macrophages at 100 μg/ml. Only one of the compounds had an anti-amas tigote activity similar to that of reference drugs at 10 μg/ml, but unfortunately this disappear ed at lower concentrations. Creator An entity primarily responsible for making the resource Muelas, Susana Di Maio, R Cerecetto, Hugo <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=502f70a0642a910f5abf0e0d5c853b61">Seoane, Gustavo</a> Ochoa, C Escario, J. A Gómez Barrio, A Source A related resource from which the described resource is derived Folia Parasitologica v. 48, no. 2, 2001. -- p. 105-108 Publisher An entity responsible for making the resource available Institute of Parasitology Date A point or period of time associated with an event in the lifecycle of the resource 2001 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI: 10.14411/fp.2001.015 Trypanosoma cruzi https://riquim.fq.edu.uy/files/original/faf927c83abf284f857db6b1b9f1cb18.pdf 47a04f8f934ca1a865868e503e4e507f https://riquim.fq.edu.uy/files/original/5a40a09a9762a91ce8788da3d243695a.jpg a870322a4b3f0ebecf6f7947ec9463de Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 105 Width 80 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New trends along hydrogen polyoxides: unusually long oxygen–oxygen bonds in H2O6 and H2O7 Subject The topic of the resource TERMOQUIMICA POLIOXIDOS BIBLIOGRAFIA NACIONAL QUIMICA 2014 Abstract A summary of the resource. By means of coupled cluster, G4 and B3LYP calculations, we characterised polyoxides H2O6 and H2O7. These two molecules behave very differently from lower polyoxides, given that some isomers present unusual bonding. In the case of H2O6, the central OO bond is predicted, to be 1.909A° , at the CCSD(T)/cc-pVTZ level. Two conformational isomers of H2O6 display nearly the same enthalpy of formation, but only one of them has extremely long OO bonds. For H2O7, the most stable isomer also has two unusually long OO bonds. At the CCSD(T) level, and after extrapolation to the complete basis set limit, this isomer is predicted to be 5.37 kcal mol–1 more stable than the one with short OO bonds, and the longest OO bond distance is expected to be close to 1.96A° . Analysis of correlation energies indicated that the new isomers found for H2O6 and H2O7 are among the most strongly correlated molecules that can be formed with first-row atoms. Creator An entity primarily responsible for making the resource <a title="Curriculum vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=330eeda61de9937431a7182c44a5ee24" target="_blank">Denis, Pablo A.</a> Pereyra Huelmo, C. Source A related resource from which the described resource is derived Molecular Physics: An International Journal at the Interface Between Chemistry and Physics v. 112, no. 23, 2014. -- p. 3047-3056 Publisher An entity responsible for making the resource available Taylor and Francis Date A point or period of time associated with an event in the lifecycle of the resource 2014 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context http://dx.doi.org/10.1080/00268976.2014.928385 https://riquim.fq.edu.uy/files/original/67d03a59970e5bc1e33d65e706804261.bmp 487290d2bd9ad3666e85f188f697e06a https://riquim.fq.edu.uy/files/original/abd944a698577a3e36b9114f5df8192b.doc 0f4e6b73dad25df0b61ca80a92a78d89 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New trends in sensory characterization of food products Subject The topic of the resource ALIMENTOS EVALUACION SENSORIAL LIBROS-ANALITICA BIBLIOGRAFIA NACIONAL QUIMICA 2013 Creator An entity primarily responsible for making the resource <a title="Currículum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=358965ab1701bacbb43e4f5a24a8e876" target="_blank">Ares, Gastón</a> <a title="Currículum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=c2b879ed74672c10135cd7d40d21e3aa" target="_blank">Giménez, Ana</a> Source A related resource from which the described resource is derived Advances in Food Science and Nutrition / editores, Visakh, P. M., Iturriaga, Laura B., Ribotta, P. D.[s.l.] : Scrivener Publishing LLC, 2013. v. 2, p. 321-360 Publisher An entity responsible for making the resource available Scrivener Publishing Date A point or period of time associated with an event in the lifecycle of the resource 2013 Rights Information about rights held in and over the resource Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora. Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Capítulo de libro Identifier An unambiguous reference to the resource within a given context DOI: 10.1002/9781118865606.ch10 Alimentos Evaluación sensorial