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                <text>&lt;strong&gt;The potential use of Mentha x piperita L., Peumus boldus Mol. and Baccharis trimera Iless. extracts as functional food ingredients&lt;/strong&gt;</text>
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                <text>We studied the comparative antioxidant and anti-glycation activities of Mentha x piperita L., Baccharis trimera Iless. and Peumus boldus Mol, in order to evaluate their potential interest as ingredients in functional foods. The total content of polyphenol compounds was determined by Folin-Ciocalteau assay as their antioxidant and anti-glycation capacities, using ABTS and ORAC for the first one and a model with methylglyoxal and bovine serum albumin for the latter. Then, paraoxonase 1 (PON 1) arylesterase activity was measured as well as apolipoprotein A-1 (ApoA-1) structure by SDS-PAGE, in the presence of an oxidative agent and the herbal extracts. Finally, the same procedure was applied to high density lipoprotein (HDL) particles using a Lipoprint kit. Results show that herbal extracts have a considerable amount of total polyphenols, thus a high antioxidant activity and a considerable anti-glycation activity. Furthermore, these extracts restore PON 1 activity as well as the original configuration of apoA-1 and the distribution of HDL subclasses, favouring anti-atherogenic particles. These herbal extracts are interesting targets to use as ingredients in functional foods.</text>
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                <text>&lt;strong&gt;Irazusta, Agustina&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Caccavello, Russell&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Panizzolo, Luis Alberto&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Gugliucci, Alejandro.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Medrano, Alejandra&lt;/strong&gt;</text>
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                <text>International Journal of Food and Nutrition Research v. 2, no. 14, 2018. -- 13 p.</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor &lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DOI: 10.28933/ijfnr-2018-09-1001</text>
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                <text>&lt;strong&gt;Antibody Profile of Colostrum and the Effect of Processing in Human Milk Banks : Implications in Immunoregulatory Properties&lt;/strong&gt;</text>
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                <text>BANCOS DE LECHE</text>
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                <text>PROPIEDADES INMUNOREGULADORAS</text>
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                <text>BACKGROUND: When feeding preterm infants, donor milk is preferred if the mother's own milk is unavailable. Pasteurization may have detrimental effects on bioactivity, but more information is needed about its effects on the immunological compounds. Research aim: This work has two main aims: evaluate the antibody profile of colostrum and study the quantitative variations in the antibodies' level and specific reactivity after undergoing Holder pasteurization. The authors focused on immunoregulatory components of colostrum (antidietary antibodies and TGF-&amp;beta;2) in the neonatal gut. METHODS: This is a descriptive cross-sectional study of a convenience sample of 67 donated colostrum samples at different days after delivery, both raw and pasteurized. Antibody profiles were analyzed at different times during breastfeeding, and total and specific antibodies (IgM, IgA, and IgG subclasses) were compared with tetanus toxoid and ovalbumin using enzyme-linked immunosorbent assay. The processing effect on total and specific antibodies, as well as TGF-&amp;beta;2, was evaluated by paired analyses. RESULTS: No variations in immunological compounds were observed throughout the colostrum stage. The TGF-&amp;beta;2, antibodies' concentrations, and antibodies' specific reactivity after pasteurization did not vary significantly as days of lactation varied. Changes in antibody levels were dependent on isotype and IgG subclass, and IgG4 showed remarkable resistance to heating. Moreover, the effect of the pasteurization on specific reactivity was antigen dependent. CONCLUSION: The supply of relevant immunological components is stable throughout the colostrum stage. The effects of pasteurization on antibodies depend on isotype, subclass, and specificity. This information is relevant to improving the immunological quality of colostrum, especially for preterm newborns.</text>
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                <text>&lt;strong&gt;Rodr&amp;iacute;guez Camejo, Claudio&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Puyol, Arturo&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Fazio, Laura&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Villamil, Emilia&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Andina, Eliana&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Lemos, Mary&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Sir&amp;eacute;, Gabriela&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Carroscia, Lili&amp;aacute;n&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Castro, Mara&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Panizzolo, Luis Alberto&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Hern&amp;aacute;ndez, Ana&lt;/strong&gt;</text>
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                <text>Journal of Human Lactation v. 34, no. 1, 2018.-- p. 137-147</text>
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                <text>SAGE</text>
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                <text>2018</text>
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            <description>Information about rights held in and over the resource</description>
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              <elementText elementTextId="486339">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Development of copper(II)-diimine-iminodiacetate mixed ligand complexes as potential antitumor agents&lt;/strong&gt;</text>
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                <text>In order to seek for new compounds with antitumor activity, our research group is focused on copper complexes with mixed ligands. This work presents the synthesis and characterization of eight compounds with general formula [Cu(iminodiacetate)(diimine)(H2O)x], with x = 0 or 1, and their cytotoxic activities against tumor cells. The chosen diimine ligands were: 2,2́-dipyridil-amine (bam), 2,2́-bipyridine (bipy), 4,4́-dimethyl-2,2́-bipyridine (dmb), 1,10-phenanthroline (phen), 4-methyl-1,10-phenanthroline (4met-phen), 5-nitro-1,10-phenanthroline (5nitro-phen), neocuproine (neo) and bathophenanthroline (batho). Compounds were characterized in solid state using FT-IR, TGA, DSC and single crystal X-ray diffraction analyses by which five new crystal structures were determined. Common features of the coordination scheme include fac-NO + O isomerism of the iminodiacetate (ida) ligand, except for the complex with neo where the ida presents mer-NO2 isomerism. The diimine ligand completes the equatorial plane for the facial isomers, with different degrees of distortion in the octahedral or square-based pyramid geometry depending on the diimine ligand, whereas the neo is perpendicular to the equatorial plane in the latter. Studies in solution, using EPR, UV&amp;ndash;Vis spectroscopy and conductimetry, showed that the copper coordination observed in solid state is retained except for the batho complex. DNA interaction studies evidenced that the complexes bind to this biomolecule, inducing different conformational changes. Biological experiments evidenced that all complexes induce cell death in the cell line MDA-MD-231 (metastasic breast cancer line). [Cu(ida)(neo)] and [Cu(ida)(batho)] presented the highest activity. Taken all these data together we propose that [Cu(ida)(neo)] and [Cu(ida)(batho)] are good candidates for further studies in vitro and in vivo.</text>
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                <text>&lt;strong&gt;Facchin, Gianella.&lt;/strong&gt;</text>
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                <text>Inorganica Chimica Acta v. 483, 2018. -- p. 61-70</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DOI: 10.1016/j.ica.2018.07.052</text>
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                <text>&lt;strong&gt;Acumuladores de bater&amp;iacute;a del tipo Pb-&amp;aacute;cido = Storage-battery type Pb-acid (lead-acid) : placas cargadas en seco, producci&amp;oacute;n de &amp;oacute;xido de plomo para fabricaci&amp;oacute;n de bater&amp;iacute;as, test efectuado a las bater&amp;iacute;as, tecnolog&amp;iacute;a de fabricaci&amp;oacute;n (en general)&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;BATERIAS ELECTRICAS&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;PLOMO&lt;/strong&gt;</text>
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            <name>Type</name>
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                <text>1952-1966</text>
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        <name>Baterías eléctricas</name>
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        <name>Fabricación</name>
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        <name>Plomo</name>
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                  <text>Bibliografía Nacional Química</text>
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                <text>&lt;strong&gt;Traffic Light System Can Increase Healthfulness Perception : Implications for Policy Making&lt;/strong&gt;</text>
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                <text>NUTRICION</text>
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                <text>PERCEPCION DE SALUD</text>
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                <text>COMPORTAMIENTO DEL CONSUMIDOR</text>
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                <text>OBJECTIVE: To evaluate how information about low nutrient content included in the traffic light labeling system influences consumers' perception of the healthfulness of products with high content of 1 key nutrient, and to compare the traffic light system with warnings in terms of the perception of healthfulness. DESIGN: Images of front-of-pack (FOP) nutrition labels (the traffic light labeling system with different numbers of nutrients with low content, and warnings) were evaluated in study 1, whereas product labels featuring the different FOP nutrition labels were evaluated in study 2. SETTING: Online studies conducted in Montevideo, Uruguay. PARTICIPANTS: A total of 1,228 Uruguayan Facebook users. MAIN OUTCOME MEASURES: Perception of healthfulness. ANALYSIS: The researchers used ANOVA to evaluate the influence of FOP nutrition labels on perceived healthfulness. RESULTS: The inclusion of information about low nutrient content in the traffic light system statistically significantly increased the perception of the healthfulness of products with high nutrient content. Nutritional warnings showed healthfulness ratings similar to those of the simplified version of the traffic light system. CONCLUSIONS AND IMPLICATIONS: Information about low nutrient content in the traffic light system might be used to infer health, and thus could raise the perception of healthfulness and decrease the traffic light system's efficacy in discouraging the consumption of unhealthful products. A simplified version of the traffic light highlighting only high-nutrient content or nutritional warnings seems to overcome this problem.</text>
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                <text>Journal of Nutrition Education and Behavior &amp;bull; Volume 50, Number 7, 2018 v. 50, no. 7, 2018. -- p. 668-674</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;A green analytical method for the determination of Cu, Fe, Mn, and Zn in wheat flour using total reflection X-ray fluorescence&lt;/strong&gt;</text>
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                <text>ALIMENTOS</text>
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                <text>ANALISIS QUIMICO</text>
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                <text>A simple, fast, and environmentally friendly method for sample preparation and subsequent determination of Cu, Fe, Mn, and Zn in wheat flour using total reflection X-ray fluorescence (TXRF) was developed and validated. Furthermore, TXRF and two other analytical techniques currently used for elemental analysis in foodstuffs, namely flame atomic absorption spectrometry (FAAS) and electrothermal atomic absorption spectrometry (ETAAS), were compared to confirm the suitability of TXRF for routine and screening analyses of metallic elements in wheat flour. The TXRF sample preparation procedure takes around 6 min and does not require a mineralization step. Although the detection limits of the TXRF technique were higher than those of FAAS and ETAAS, they were suitable for the proposed purpose. The advantages of the proposed method are also discussed. The TXRF method was applied to the analysis of five commercial wheat flour samples representing all brands available in Montevideo, Uruguay. TXRF proved to be suitable for the determination of Cu, Fe, Mn, and Zn in wheat flour, and is a promising technique for routine and screening analyses of bakery foodstuffs.</text>
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                <text>&lt;strong&gt;Machado, Ignacio&lt;/strong&gt;</text>
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                <text>Journal of Analytical Atomic Spectroscopy v. 33, 2018. -- p. 1264-1268</text>
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                <text>Royal Society of Chemistry</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>IONES DE METAL</text>
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                <text>The nitrilotripropionic acid (H3ntp) is a flexible polycarboxylate ligand that has been used in the preparation of polynuclear compounds with several metal cations. In this work, we present the in solution study of the interaction of ntp with a wide range of metal ions (M): Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Pb(II) and Fe(III). The species [Mntp]&amp;minus;, [M(Hntp)], and [M3(Hntp)2]2+ were detected for most metal ions. In the case of Cu(II), the potentiometric model was also supported through additional thermodynamic characterization by spectroscopy. We also performed computational calculations at the UB3LYP/LANL2DZ SMD level of theory that allowed us to predict the electronic spectra of the proposed species. The computational model showed a satisfactory performance, as demonstrated by the calculated electronic spectra fit to the experimental data. A possible assembly mechanism for the reported capsule-shaped complex [Cu3(Hntp)2]2+ is proposed.</text>
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                <text>&lt;strong&gt;Mart&amp;iacute;nez, Sebasti&amp;aacute;n&lt;/strong&gt;</text>
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                <text>Inorganica Chimica Acta v. 483, 2018. -- p. 53-60</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;The Impact of Solid Dispersion on Formulation, Using Confocal Micro Raman Spectroscopy as Tool to Probe Distribution of Components&lt;/strong&gt;</text>
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                <text>DISPERSION SOLIDA</text>
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                <text>FORMULACION</text>
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                <text>ESPECTROSCOPIA RAMAN</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2018</text>
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                <text>Purpose Solid dispersions (SDs) of a poorly water-soluble drug were prepared, and their physicochemical properties were compared to those of control physical mixtures (PMs). Among the multiple techniques used to characterize the solid state of preparations, confocal micro Raman spectroscopy (CMRS) was used as a non-destructive tool to qualitatively probe content uniformity and distribution of drug and carrier. Methods SDs and PMs of drug (fenbendazole, FBZ) were prepared containing two different carriers (poloxamer P188 or P407) with different drug polymer ratios. The preparations were characterized by powder X-ray diffractometry, Fourier transform infrared spectroscopy, thermal analysis, scanning electron microscopy, and in vitro dissolution assay. In addition, CMRS technique and principal component analysis (PCA) were used in order to statistically define the content uniformity and distribution of the drug within the polymeric matrix. Results In vitro dissolution results exhibited a marked improvement when the drug was formulated as SD compared to control PM and to pure drug. The solid state of these preparations characterized by X-ray powder diffraction and Fourier transform infrared spectroscopy showed no changes in the crystalline state of the drug and no chemical interactions between the components. Raman studies showed a better content uniformity of the drug within the polymeric matrix when subjected to SD process, correlating with the improved dissolution profile. Conclusion This study provides evidence of the potential of the confocal Raman imaging technique, providing a fast and powerful method to characterize solid dispersions which could be incorporated towards the use of quality by design (QbD) approaches in pharmaceutical development.</text>
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                <text>&lt;strong&gt;Melian, M. Elisa&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Mungu&amp;iacute;a, A. Beatriz&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=fc7cd71892b1a9968ee19230dafdbd01" target="_blank"&gt;&lt;strong&gt;Faccio, Ricardo.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Palma, Santiago&lt;/strong&gt;</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="487026">
                <text>Journal of Pharmaceutical Innovation |g v. 13, 2018. -- p. 58-68</text>
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            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="487027">
                <text>Springer</text>
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                <text>2018</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="487029">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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              <elementText elementTextId="487030">
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            <elementTextContainer>
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                <text>Ingl&amp;eacute;s</text>
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        <name>Dispersion Solida</name>
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        <name>Espectroscopía de Raman</name>
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        <name>Formulación</name>
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                  <text>Bibliografía Nacional Química</text>
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              <description>An account of the resource</description>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                  <text>Departamento de Documentación y Biblioteca</text>
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                  <text>RIQUIM</text>
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          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>PDF</text>
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                <text>&lt;strong&gt;Morphoanatomy and essential oil analysis of Baccharis trimera (Less.) DC. (Asteraceae) from Uruguay&lt;/strong&gt;</text>
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                <text>ACEITES ESENCIALES</text>
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                <text>MORFOANATOMIA VEGETAL</text>
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                <text>URUGUAY</text>
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                <text>BACCHARIS TRIMERA</text>
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                <text>ASTERACEAE</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2018</text>
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                <text>Baccharis trimera (Less.) DC. (Asteraceae), &amp;lsquo;carqueja', is a medicinal plant native from South America employed as decoction or infusion for the treatment of low to moderate ailments, and included in the Brazilian Pharmacopeia. This plant is also a rich source of essential oil (EO) valuable in the fragrance industry, mainly owing to carquejyl acetate, carquejol and several sesquiterpenic alcohols contributing to its characteristic aroma reminisce of rosewood. In this work, we report the EO composition, morpho-anatomical and histochemical characterization of B. trimera growing wild in Uruguay. 150 compounds were identified by gas chromatography-mass spectrometry (GC&amp;ndash;MS), 79 of them not previously reported for this species, whose relative proportions varied according the season. Anatomically, the specimens analyzed did not present any leaves nor ribs between the wings. The epidermis presented polygonal cells with straight anticlinal walls, with anisocytic and less frequently anomocytic stomata. Non-glandular (multicellular, unistratified, with a characteristic elongated apex cell) and glandular (multicellular, bistratified, EO positive) trichomes were evidenced. The mesophyll at the wing level was isolateral with a central spongy parenchyma. Schyzogenous ducts with bistratified secretory epithelium (EO and polyphenols positive), were occasionally associated with the endodermis. The perimedullar parenchyma of the cladodes presented polyhedral pyramidal and prismatic crystals of calcium oxalate, according to previous reports.</text>
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                <text>&lt;strong&gt;Minteguiaga, Manuel&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Mercado, Mar&amp;iacute;a I.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Ponessa, Graciela I.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Catal&amp;aacute;n, C&amp;eacute;sar A. N.&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2df81feedac99473a4e536d2623f04c3" target="_blank"&gt;&lt;strong&gt;Dellacassa, Eduardo.&lt;/strong&gt;&lt;/a&gt;</text>
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            <name>Source</name>
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                <text>Industrial Crops &amp;amp; Products v. 112, 2018. --&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp; p. 488-498</text>
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              <elementText elementTextId="487053">
                <text>Elsevier</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="487055">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DOI: 10.1016/j.indcrop.2017.12.040</text>
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                <text>&lt;strong&gt;Synthesis, spectroscopic characterization and structural study of 2- isopropenyl-3-methylphenol, carquejiphenol, a carquejol derivative with potential medicinal use&lt;/strong&gt;</text>
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                <text>PLANTAS MEDICINALES</text>
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                <text>CARQUEJIFENOL</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>In this work, 2-isopropenyl-3-methylphenol, hereafter referred to as carquejiphenol (CARP), a minor component of &amp;ldquo;carqueja&amp;rdquo; essential oil, was synthesized starting from carquejol and characterized by using Fourier Transform infrared (FT-IR) and Raman (FT-Raman) spectroscopies, Ultraviolet&amp;ndash;Visible (UV&amp;ndash;Visible) spectroscopy, Electron Impact Mass spectrometry (EI-MS), Hydrogen and Carbon Nuclear Magnetic Resonance (1H- and 13C-NMR) and 2D 1H1H gCOSY, 1H13C gHSQC, 1H13C gHMBC experiments. A very good correlation between the predicted FTIR, FTRaman, UV&amp;ndash;visible and 1H13C-NMR spectra for monomer and dimer of CARP by using theoretical B3LYP/6-31G* and 6-311++G** calculations with the corresponding experimental ones was observed. The solvation energies for CARP were predicted by using both levels of calculations and considering the solvent effects with the polarised continuum and solvation models. The increase in volume in solution supports the H bonds formation due to the presence in its structure of an OH group, as revealed by atoms in molecules (AIM) analysis. A high stability for CARP was found by using natural bond orbital (NBO) and AIM studies, while the investigation of the frontier orbitals reveals that CARP is more reactive than carquejol and N-(3,4-dimethoxybenzyl)-hexadecanamide but less reactive than the sesquiterpene lactone cnicin. The proximity of both the electrophilicy and nucleophilicity index of CARP with those obtained respectively for carquejol and for N-(3,4-dimethoxybenzyl)-hexadecanamide, suggests that CARP could probably present pharmacological properties. The scaled quantum mechanical force field (SQMFF) methodology was used to compute the harmonic force fields and to perform the complete vibrational analysis. In this way, 63 normal modes of vibration were assigned and compared with other terpene substances.</text>
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                <text>&lt;strong&gt;Minteguiaga, Manue&lt;/strong&gt;</text>
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                <text>&lt;a title="Curiculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2df81feedac99473a4e536d2623f04c3" target="_blank"&gt;&lt;strong&gt;Dellacassa, Eduardo.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Iramain, Maximiliano A.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Catal&amp;aacute;n, C&amp;eacute;sar A. N.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Brand&amp;aacute;n, Silvia Antonia&lt;/strong&gt;</text>
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                <text>&lt;p&gt;Journal of Molecular Structure |g v. 1165, 2018. --&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp; p. 332-343&lt;/p&gt;</text>
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            <name>Publisher</name>
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                <text>Elsevier</text>
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                <text>2018</text>
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            <name>Rights</name>
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              <elementText elementTextId="487212">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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            <name>Format</name>
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                <text>PDF</text>
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            <name>Language</name>
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                <text>Ingl&amp;eacute;s</text>
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                <text>Art&amp;iacute;culo</text>
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                <text>DOI: 10.1016/j.molstruc.2018.04.001</text>
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        <name>Carquejifenol</name>
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        <name>Espectro vibracional</name>
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        <name>Espectroscopía</name>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>Papel</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="487165">
                <text>&lt;strong&gt;Estimaci&amp;oacute;n de cloro libre en aguas industriales&lt;/strong&gt;</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>&lt;strong&gt;CLORO&lt;/strong&gt;</text>
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              <elementText elementTextId="487167">
                <text>&lt;strong&gt;AGUA INDUSTRIAL&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;EVALUACION&lt;/strong&gt;</text>
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              <elementText elementTextId="487169">
                <text>&lt;strong&gt;FREE CHLORINE&lt;/strong&gt;</text>
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              <elementText elementTextId="487170">
                <text>&lt;strong&gt;WATER&lt;/strong&gt;</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="487171">
                <text>Biblioteca-FQ</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="487172">
                <text>1986</text>
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            </elementTextContainer>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="487173">
                <text>Papel</text>
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              <elementText elementTextId="487174">
                <text>PDF</text>
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            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="487175">
                <text>Ingl&amp;eacute;s</text>
              </elementText>
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          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
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              <elementText elementTextId="487176">
                <text>Bibliograf&amp;iacute;a</text>
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          </element>
          <element elementId="116">
            <name>Temporal Coverage</name>
            <description>Temporal characteristics of the resource.</description>
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              <elementText elementTextId="487177">
                <text>1948-1960</text>
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      <tag tagId="5750">
        <name>Agua industrial</name>
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      <tag tagId="4514">
        <name>Cloro</name>
      </tag>
      <tag tagId="2819">
        <name>Evaluación</name>
      </tag>
      <tag tagId="5751">
        <name>Free chlorine</name>
      </tag>
      <tag tagId="5752">
        <name>Water</name>
      </tag>
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  </item>
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        <src>https://riquim.fq.edu.uy/files/original/e51d1da5d4539b8cc4b8428215889a1f.pdf</src>
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                <name>Bit Depth</name>
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                    <text>8</text>
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                    <text>111</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Bibliografía Nacional Química</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Departamento de Documentación y Biblioteca</text>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>PDF</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Emulating porphyrins with a rippled multivacancy graphene system&lt;/strong&gt;</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="487223">
                <text>GRAFENO</text>
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              <elementText elementTextId="487224">
                <text>PORFIRINA</text>
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          <element elementId="87">
            <name>Abstract</name>
            <description>A summary of the resource.</description>
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                <text>The interaction between a complex porphyrin-like system formed by an iron atom and multivacant graphene layer and O2, CO and CO2 molecules is studied, using Density Functional Theory (DFT) calculations. The multivacancy graphene system used for this study, consists in the removal of a 1,4-dimethybenzene-like moiety, in a 6 &amp;times; 6 supercell. This removal and the structural optimization subsequently performed, yield to a biaxial vacancy, where the location of an iron atom embedded in it, lead to a system with resemblance to iron-porphyrin systems. This similar structure could be used to form complexes where gas molecules are allowed to interact with these iron-octavacant graphene systems. The study focuses on the structure of the system and the net magnetic moment for different gas molecules: O2, CO2 and CO. Rippling in the vacant graphene is enhanced through this interaction</text>
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            <name>Creator</name>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=fc7cd71892b1a9968ee19230dafdbd01" target="_blank"&gt;&lt;strong&gt;Faccio, Ricardo.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=31ed37f6d0196c1ca18c1b4dfab6de76" target="_blank"&gt;&lt;strong&gt;Mombr&amp;uacute;, &amp;Aacute;lvaro W.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Mombr&amp;uacute;, Dominique&lt;/strong&gt;</text>
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                <text>&lt;p&gt;Applied Surface Science |g v. 436, 2018. --&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp; p. 1173-1180 &lt;/p&gt;</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="487232">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho de&lt;/strong&gt; autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>In this report, we used ab initio calculations in order to study the effect of Pt doping in monolayer MoS2. The Pt doping introduces important distortions at the geometrical levels, that induces the appearance of impurity levels, expressed as flat bands, in the proximity of the Fermi level, thus reducing the band gap. The vibrational analysis confirms the reduction of symmetry, and the simulated off-resonance Raman spectra presents important differences when comparted with pristine MoS2 monolayer, with relevant bands located at &amp;sim;50, 150, 220, 300 and 330 cm&amp;minus;1. All this confirm that Pt doping could be possible, allowing electronic and vibrational tuning of their properties and this work provides the tool for a potential identification of these modifications at the experimental level.</text>
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&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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