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                  <text>Bibliografía Nacional Química</text>
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                <text>Impact of plain packaging of cigarettes on the risk perception of Uruguayan smokers : an experimental study</text>
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                <text>CIGARRILLOS</text>
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                <text>Background Uruguay, a South American country of 3.4 million inhabitants that has already banned tobacco advertising, prohibited such terms as light, mild and low-tar and required graphic warnings covering 80% of cigarette packs, is considering the imposition of plain, standardised packaging.&#13;
&#13;
Methods We conducted an experimental choice-based conjoint analysis of the impact of alternative cigarette package designs on the risk perceptions of 180 adult current Uruguayan smokers. We compared plain packaging, with a standardised brand description and the dark brown background colour required on Australian cigarette packages, to two controls: the current package design with distinctive brand elements and colours; and a modified package design, with distinctive brand elements and the dark brown background colour. Graphic warnings were also varied.&#13;
&#13;
Results Plain packaging significantly reduced the probability of perceiving the stimulus cigarettes as less harmful in comparison to the current package design (OR 0.398, 95% CI 0.333 to 0.476, p&lt;0.001) and the modified package design (OR 0.729, 95% CI 0.626 to 0.849, p&lt;0.001).&#13;
&#13;
Conclusions Plain packaging enhanced the perceived risk of cigarette products even in a highly regulated setting such as Uruguay. Both the elimination of distinctive brand elements and the use of Australia’s dark brown background colour contributed to the observed effect.</text>
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                <text>&lt;strong&gt;Harris, Jeffrey E.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Triunfo, Patricia.&lt;/strong&gt;</text>
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                <text>Tobacco Control&amp;nbsp; v. 27, no. 5, 2018. -- p. 513-518</text>
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                <text>BMJ Publishing Group Ltd.</text>
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              <elementText elementTextId="495018">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DOI: 10.1136/tobaccocontrol-2017-053639</text>
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                <text>Uruguay</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                <text>&lt;strong&gt;QM/MM Studies of Dph5 &amp;ndash; A Promiscuous Methyltransferase in the Eukaryotic Biosynthetic Pathway of Diphthamide&lt;/strong&gt;</text>
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                <text>ENZIMAS</text>
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                <text>EUCARIOTICA BIOSINTETICA</text>
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                <text>Eukaryotic diphthine synthase, Dph5, is a promiscuous methyltransferase that catalyzes an extraordinary N,O-tetramethylation of 2-(3-carboxy-3-aminopropyl)-l-histidine (ACP) to yield diphthine methyl ester (DTM). These are intermediates in the biosynthesis of the post-translationally modified histidine residue diphthamide (DTA), a unique and essential residue part of the eukaryotic elongation factor 2 (eEF2). Herein, the promiscuity of Saccharomyces cerevisiae Dph5 has been studied with in silico approaches, including homology modeling to provide the structure of Dph5, protein&amp;ndash;protein docking and molecular dynamics to construct the Dph5-eEF2 complex, and quantum mechanics/molecular mechanics (QM/MM) calculations to outline a plausible mechanism. The calculations show that the methylation of ACP follows a typical SN2 mechanism, initiating with a complete methylation (trimethylation) at the N-position, followed by the single O-methylation. For each of the three N-methylation reactions, our calculations support a stepwise mechanism, which first involve proton transfer through a bridging water to a conserved aspartate residue D165, followed by a methyl transfer. Once fully methylated, the trimethyl amino group forms a weak electrostatic interaction with D165, which allows the carboxylate group of diphthine to attain the right orientation for the final methylation step to be accomplished.</text>
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                <text>&lt;strong&gt;H&amp;ouml;rberg, Johanna&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Eriksson, Leif A&lt;/strong&gt;</text>
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                <text>Journal of Chemical Information and Modeling&amp;nbsp; v. 58, no. 7, 2018. -- p. 1406-1414</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DOI: 10.1021/acs.jcim.8b00217</text>
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                <text>&lt;strong&gt;Hematobin is a novel immunomodulatory protein from the saliva of the horn fly Haematobia irritans that inhibits the inflammatory response in murine macrophages&lt;/strong&gt;</text>
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                <text>PROTEINAS</text>
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                <text>SALIVA</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>Background The horn fly Haematobia irritans is a blood-sucking ectoparasite responsible for substantial economic loss of livestock. Like other hematophagous arthropods species, the successful blood-feeding of H. irritans is highly dependent on the modulation of the host&amp;rsquo;s hemostasis and immune system. Here, we evaluated the biological activity of hematobin (HTB), a protein recently identified in the H. irritans saliva, on macrophage biology. The goal was to understand the putative interactions between the components of H. irritans saliva and the early host immune responses. Results Thioglycolate-elicited peritoneal macrophages from BALB/c mice were stimulated by lipopolysaccharide (LPS) plus interferon-&amp;gamma; (IFN-&amp;gamma;) in the presence or absence of recombinant HTB. The presence of the salivary protein in the cultures inhibited nitric oxide production and decreased the inducible nitric oxide synthase (iNOS) expression induced by LPS plus IFN-&amp;gamma;. The tumor necrosis factor-&amp;alpha; (TNF-&amp;alpha;) and interleukin-12p40 (IL-12p40) levels were also reduced in the macrophages pre-incubated with HTB; these findings correlated to the decreased NF-&amp;kappa;B expression. The biological activities described here were not associated with changes in annexin V binding to macrophages suggesting that HTB does not induce cell death. In addition, the activity of HTB seems to be specific to macrophages because no changes were observed in lymphocyte proliferation or cytokine production. Conclusions We describe here the first bioactive salivary protein of H. irritans. We characterized its ability to modulate macrophage inflammatory response, and the results can help explain how horn flies modulate the host immune system to feed on blood.</text>
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                <text>&lt;strong&gt;Breijo, Mart&amp;iacute;n&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Esteves, Eliane&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Bizarro, Bruna&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Lara, Priscila G.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Assis, Josiane B.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Rocha, Sergio&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pastro, Luc&amp;iacute;a.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Fern&amp;aacute;ndez, Cecilia.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Meikle, Ana&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Sa Nunes, Anderson&lt;/strong&gt;</text>
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                <text>Parasites and Vectors v. 11, no. 1, 2018. -- 11p.--e13071-018.3017z</text>
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                <text>BioMed Central Ltd</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Effect of irrigation and timing and type of nitrogen application on the biochemical composition of Vitis vinifera L. cv. Chardonnay and Syrah grapeberries&lt;/strong&gt;</text>
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                <text>UVAS</text>
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                <text>AMINOACIDOS</text>
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                <text>COMPOSICION BIOQUIMICA</text>
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                <text>ANALISIS SENSORIAL</text>
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                <text>VITIS VINIFERA L</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA 6530 |a</text>
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                <text>This study reports the effect of different doses of nitrogen applied to soil and/or leaves of Syrah and Chardonnay grapevines in the Languedoc-Roussillon (France) over two years. In 2011, nitrogen treatment involved both foliar urea sprayings and soil application at two different levels, with two controls - irrigated without nitrogen and no irrigation nor nitrogen. In 2012, the same grapevines received either soil or foliar nitrogen using the same controls. Results showed that foliar application increased the amino acid content to a greater extent than soil application, but that a combination of both was the most effective. For the first time, significantly elevated proline levels in response to drought were demonstrated for the grapevine. Increased contents of aromatic compounds and glycosylated precursors closely mirrored the applied nitrogen dose. Wines produced from N-fertilized Syrah grapes in 2011 showed a statistically significant effect of irrigation and fertilization on positive sensorial perception.</text>
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                <text>Ojeda, Hernan</text>
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                <text>Food Chemistry&amp;nbsp; v. 241, 2018. -- p. 171-181</text>
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            <description>Information about rights held in and over the resource</description>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>DOI: 10.1016/j.foodchem.2017.07.114</text>
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                <text>&lt;strong&gt;An&amp;aacute;lisis de datos sensoriales de tomate triturado con l&amp;oacute;gica difusa y t&amp;eacute;cnicas multivariadas&lt;/strong&gt;</text>
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                <text>El conjunto de las t&amp;eacute;cnicas de recolecci&amp;oacute;n y an&amp;aacute;lisis de datos, generados en la evaluaci&amp;oacute;n sensorial, constituye una rama de la estad&amp;iacute;stica llamada sensometr&amp;iacute;a. Si se tiene en cuenta la vaguedad e incertidumbre con la que se manifiestan las percepciones humanas, la estrategia m&amp;aacute;s apropiada para obtener conocimiento preciso a partir de valoraciones subjetivas, consiste en transformar los datos sensoriales mediante la matem&amp;aacute;tica borrosa. No obstante el potencial que muestra el razonamiento borroso, en la actualidad, existen pocas referencias sobre la aplicaci&amp;oacute;n de la l&amp;oacute;gica difusa en la evaluaci&amp;oacute;n sensorial, y no se dispone de criterios y m&amp;eacute;todos armonizados y sistematizados para una evaluaci&amp;oacute;n sensorial objetiva y reproducible, en alimentos vegetales. Los resultados obtenidos en pruebas sensoriales en tomate triturado, permitieron exponer un marco metodol&amp;oacute;gico para el an&amp;aacute;lisis sensom&amp;eacute;trico de datos borrosos con la utilizaci&amp;oacute;n de la l&amp;oacute;gica difusa y m&amp;eacute;todos de an&amp;aacute;lisis multivariado de datos. De esta manera se optimizan las t&amp;eacute;cnicas en las pruebas sensoriales, para as&amp;iacute; renovar el proceso de an&amp;aacute;lisis sensorial, desarrollando un &amp;aacute;rea espec&amp;iacute;fica que mejorar&amp;aacute; el valor econ&amp;oacute;mico en la producci&amp;oacute;n alimentaria argentina.</text>
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                <text>Revista de la Facultad de Ciencias Agrarias de la Universidad Nacional de Cuyo v. 50, no. 1, 2018. --&amp;nbsp; p. 233-248</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;The effect of cation modifier on improving the luminescent properties of borate glasses doped with Yb3 + and Er3 +&lt;/strong&gt;</text>
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                <text>In this work we present the preparation and characterization of new fluoroborate glasses doped with Yb3 + and Er3 + and modified by Ca, Sr and Ba oxides. Glasses with compositions (100-x-y) (MO &amp;sdot; 2B2O3) + x NaF + y (YbF3:ErF3) (% in mol), where M is Sr, Ba, Ca, x = 10&amp;ndash;30% and y = 0, 1 or 5% were prepared by the melt/quenching technique. Glass forming ability and stability were studied by thermal analysis and it is shown that calcium samples presented the highest stability. The nature of the modifier cation has also shown a direct influence on the absolute and relative intensities of the rare earth ions transitions in the visible and near-infrared regions. Though the calcium samples present lower absorption intensities, they display the best up- and down-conversion efficiencies. There are evidences that the incorporation of the fluoride compound leads to a fluorine rich environment on the first coordination sphere of the RE, decreasing the probability of OH&amp;ndash; groups &amp;ndash; well known quenchers of RE emissions. Though preliminary, the results in this study can become of relevance for the field of solar cell technology improvement via betterment of solar light harvesting in the infrared and ultraviolet regions.</text>
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                <text>Journal of Non-Crystalline Solids v. 483, 2018. -- p. 79-85</text>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Vitamina F : identificaci&amp;oacute;n y dosificaci&amp;oacute;n en cremas&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;QUIMICA ANALITICA&lt;/strong&gt;</text>
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                <text>Biblioteca-FQ</text>
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          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Lentes de contacto : solucioes de limpieza, soluciones de mantenimiento, soluciones para su aplicaci&amp;oacute;n para distintos tipos, preparaci&amp;oacute;n de dichas soluciones&lt;/strong&gt;</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>&lt;strong&gt;LENTES DE CONTACTO&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;SOLUCIONES (LIQUIDOS)&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;TECNICAS DE PRODUCCION&lt;/strong&gt;</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Biblioteca-FQ</text>
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            <description>The file format, physical medium, or dimensions of the resource</description>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>Ingl&amp;eacute;s</text>
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            <name>Type</name>
            <description>The nature or genre of the resource</description>
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                <text>Bibliograf&amp;iacute;a</text>
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            <name>Temporal Coverage</name>
            <description>Temporal characteristics of the resource.</description>
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                <text>1968-1986</text>
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        <name>Lentes de contacto</name>
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        <name>Soluciones (líquidos)</name>
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        <name>Técnicas de producción</name>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Ozono en hospitales y laboratorios como desinfectante, bactericida, etc.&amp;nbsp; : en cirug&amp;iacute;a, en todos los ambientes&lt;/strong&gt;</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>&lt;strong&gt;OZONO&lt;/strong&gt;</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Biblioteca-FQ</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>1989</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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                <text>PDF</text>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>Ingl&amp;eacute;s</text>
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            <name>Type</name>
            <description>The nature or genre of the resource</description>
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                <text>Bibliograf&amp;iacute;a</text>
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            <name>Temporal Coverage</name>
            <description>Temporal characteristics of the resource.</description>
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                <text>1976-1981</text>
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        <name>Antiinfecciosos</name>
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        <name>Laboratorios</name>
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        <name>Ozono</name>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Bibliografía Nacional Química</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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              <name>Contributor</name>
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                  <text>Departamento de Documentación y Biblioteca</text>
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                  <text>RIQUIM</text>
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          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Leaf saponins of Quillaja brasiliensis enhance long-term specific immune responses and promote dose-sparing effect in BVDV experimental vaccines&lt;/strong&gt;</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>SAPONINAS</text>
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                <text>INMUNOLOGIA</text>
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                <text>QUILLAJA BRASILIENSIS</text>
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                <text>VACUNAS</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2018</text>
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                <text>Saponin-based adjuvants are promising adjuvants that enhance both humoral and T-cell-mediated immunity. One of the most used natural products as vaccine adjuvants are Quillaja saponaria bark saponins and its fraction named Quil A&amp;reg;. Despite that, its use has been restricted for human use due to safety issues. As an alternative, our group has been studying the congener species Quillaja brasiliensis saponins and its performance as vaccine adjuvants, which have shown to trigger humoral and cellular immune responses comparable to Quil A&amp;reg; but with milder side effects. Here, we studied a semi purified aqueous extract (AE) and a previously little characterized saponin-enriched fraction (QB-80) from Q. brasiliensis as vaccine adjuvants and an inactivated virus (bovine viral diarrhea virus, BVDV) antigen co-formulated in experimental vaccines in mice model. For the first time, we show the spectra pattern of the Q. brasiliensis saponins by MALDI-TOF, a novel and cost-effective method that could be used to characterize different batches during saponins production. Both AE and QB-80 exhibited noteworthy chemical similarities to Quil A&amp;reg;. In addition, the haemolytic activity and toxicity were assessed, showing that both AE and QB-80 were less toxic than Quil A&amp;reg;. When subcutaneously inoculated in mice, both fractions promoted long-term strong antibody responses encompassing specific IgG1 and IgG2a, enhanced the avidity of IgG antibodies, induced a robust DTH reaction and significantly increased IFN-ɣ production in T CD4+ and T CD8+ cells. Furthermore, we have proven herein that AE has the potential to promote dose-sparing, substantially reducing the dose of antigen required for the BVDV vaccines and still eliciting a mixed Th1/Th2 strong immune response. Based on these results, and considering that AE is a raw extract, easier and cheaper to produce than commercially available saponins, this product can be considered as candidate to be escalated from experimental to industrial uses.</text>
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            <description>An entity primarily responsible for making the resource</description>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA - &lt;/strong&gt;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>We investigated the occurrence of cycloadditions on dimensional boron nitride. Our results indicated that the [2 + 2] cycloaddition of benzynes, ethyne, and maleic anhydride is allowed both from thermodynamical and kinetic stand points. In fact, our results indicated that the reaction energy associated with the formation of the [2 + 2] cycloaddition product is more exothermic than that computed for graphene. The activation energy determined for the [2 + 2] path is 15.9 kcal/mol, suggesting the feasibility of the process. Furthermore, we found that the activation energy for the retro reaction is 30.6 kcal/mol. This value is large enough to guarantee the stability of the functional groups but not too high to impede their detachment upon heating. In addition to these findings, we found that cycloadditions can be used to reduce the band gap of boron nitride nanosheets. In light of these results, we propose the use of cycloaddition reactions to attain the temperature-controlled functionalization of boron nitride sheets.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Phage borne peptides isolated from phage libraries have proven to be valuable reagents for the development of small-molecule immunoassays. However, the large size, low diffusion rate, and biological nature of the phage particles create some limitations to their use and require secondary reagents for its detection. In this work, we explore the use of the Nano luciferase (NanoLuc) as a fusion partner to generate recombinant tracers for immunoassay development. The imidaclothiz peptidomimetic C2-15 that specifically binds to the anti-imidaclothiz monoclonal antibody (mAb) 1E7 was fused to NanoLuc, both at the N terminus (C2-15-NanoLuc) and C terminus (NanoLuc-C2-15). NanoLuc-C2-15 showed better performance than C2-15-NanoLuc and was adopted to develop a bioluminescent enzyme immunoassay (BLEIA) and a bioluminescence lateral flow immunoassay (BLLFIA) for imidaclothiz. The luminescence signal of NanoLuc-C2-15 rapidly reaches high intensity with slow attenuation, which enabled one to capture the BLLFIA readout by using a smartphone without an external light source. The IC50 of the BLEIA and BLLFIA were 3.3 &amp;plusmn; 0.2 and 6.4 &amp;plusmn; 0.4 ng mL-1, respectively. Both immunoassays exhibited good accuracy for the detection of imidaclothiz in environmental and agricultural samples.</text>
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                <text>Analytical Chemistry&amp;nbsp; v. 90, no. 3, 2018. -- p. 2230-2237</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Using the flexible ligand oxydiacetic acid (H2oda), ten new heteropolynuclear compounds with general formula [Ln2Zn3(oda)6]&amp;middot;xH2O (Ln = lanthanide ion, oda = oxydiacetate) were synthesized and structurally characterized. They were prepared by the direct reaction of oda in aqueous solution with stoichiometric amounts of Zn and Ln salts, followed by slow organic solvent diffusion. Two different structures were obtained: the larger lanthanides Pr, Nd, Eu and Tb gave compounds belonging to the hexagonal system, space group P6/mcc; whereas, the smaller ones, Ho, Er, Yb and Y formed cubic systems, space group Fd[3 with combining macron]c. In the case of Dy, the two polymorphs were obtained by slight variations in the synthetic conditions. The phase change observed is discussed in comparison with previously reported [Ln2M3(oda)6]&amp;middot;xH2O compounds (M = bivalent metal ion). Luminescence studies were also carried out. Compounds containing Eu and Tb showed the most intense luminescence, also bearing relatively long lifetimes for the excited state deactivation. The luminescence profiles of both Dy systems are independent of the hexagonal or cubic arrangements, due to the similar environment of the Ln having the same point symmetry.</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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            <element elementId="37">
              <name>Contributor</name>
              <description>An entity responsible for making contributions to the resource</description>
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                <elementText elementTextId="709199">
                  <text>Departamento de Documentación y Biblioteca</text>
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                  <text>RIQUIM</text>
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          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>PDF</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>&lt;strong&gt;Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling&lt;/strong&gt;</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496123">
                <text>PEPTIDOS</text>
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              <elementText elementTextId="496124">
                <text>PEQUE&amp;Ntilde;AS MOLECULAS</text>
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              <elementText elementTextId="496125">
                <text>OXIGENO LUMINISCENTE</text>
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              <elementText elementTextId="496126">
                <text>NANOPEPTAMER</text>
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              <elementText elementTextId="496127">
                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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              <elementText elementTextId="496128">
                <text>2018</text>
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          <element elementId="87">
            <name>Abstract</name>
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              <elementText elementTextId="496129">
                <text>Our group has previously developed immunoassays for noncompetitive detection of small molecules based on the use of phage borne anti-immunocomplex peptides. Recently, we substituted the phage particles by biotinylated synthetic anti-immunocomplex peptides complexed with streptavidin and named these constructs nanopeptamers. In this work, we report the results of combining AlphaLisa, a commercial luminescent oxygen channeling bead system, with nanopeptamers for the development of a noncompetitive homogeneous assay for the detection of small molecules. The signal generation of AlphaLisa assays relies on acceptor-donor bead proximity induced by the presence of the analyte (a macromolecule) simultaneously bound by antibodies immobilized on the surface of these beads. In the developed assay, termed as nanoAlphaLisa, bead proximity is sustained by the presence of a small model molecule (atrazine, MW = 215) using an antiatrazine antibody captured on the acceptor bead and an atrazine nanopeptamer on the donor bead. Atrazine is one of the most used pesticides worldwide, and its monitoring in water has relevant human health implications. NanoAlphaLisa allowed the homogeneous detection of atrazine down to 0.3 ng/mL in undiluted water samples in 1 h, which is 10-fold below the accepted limit in drinking water. NanoAlphaLisa has the intrinsic advantages for automation and high-throughput, simple, and fast homogeneous detection of target analytes that AlphaLisa assay provides.</text>
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              <elementText elementTextId="496130">
                <text>&lt;strong&gt;Lassabe, Gabriel&lt;/strong&gt;</text>
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              <elementText elementTextId="496131">
                <text>&lt;strong&gt;Kramer, Karl&lt;/strong&gt;</text>
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              <elementText elementTextId="496132">
                <text>&lt;strong&gt;Hammock, Bruce D.&lt;/strong&gt;</text>
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              <elementText elementTextId="496133">
                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=7ee0def1187be47e0710e877d9768b5a" target="_self"&gt;&lt;strong&gt;Gonz&amp;aacute;lez Sapienza, Gualberto&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=67c04f6a200d5de027ddb6804d7bae5f" target="_self"&gt;&lt;strong&gt;Gonz&amp;aacute;lez Techera, Andr&amp;eacute;s.&lt;/strong&gt;&lt;/a&gt;</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="496135">
                <text>Analytical Chemistry v. 90, no. 10, 2018. -- p. 6187-6192</text>
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            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="496136">
                <text>American Chemical Society</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496137">
                <text>2018</text>
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            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496138">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496139">
                <text>PDF</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496140">
                <text>Ingl&amp;eacute;s</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496141">
                <text>Art&amp;iacute;culo</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="496142">
                <text>DOI: 10.1021/acs.analchem.8b04536</text>
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            </elementTextContainer>
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      <tag tagId="6040">
        <name>Nanopeptamer</name>
      </tag>
      <tag tagId="6039">
        <name>Oxigeno Luminiscente</name>
      </tag>
      <tag tagId="329">
        <name>Péptidos</name>
      </tag>
      <tag tagId="6038">
        <name>Pequeñas Moleculas</name>
      </tag>
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        <src>https://riquim.fq.edu.uy/files/original/1690aca413b6f21dae766e71b7d065c6.jpg</src>
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            <name>Omeka Image File</name>
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            <elementContainer>
              <element elementId="74">
                <name>Bit Depth</name>
                <description/>
                <elementTextContainer>
                  <elementText elementTextId="496176">
                    <text>8</text>
                  </elementText>
                </elementTextContainer>
              </element>
              <element elementId="75">
                <name>Channels</name>
                <description/>
                <elementTextContainer>
                  <elementText elementTextId="496177">
                    <text>3</text>
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              <element elementId="73">
                <name>Height</name>
                <description/>
                <elementTextContainer>
                  <elementText elementTextId="496180">
                    <text>84</text>
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                <name>Width</name>
                <description/>
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                    <text>146</text>
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      <name>Document</name>
      <description>A resource containing textual data.  Note that facsimiles or images of texts are still of the genre text.</description>
      <elementContainer>
        <element elementId="7">
          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
          <elementTextContainer>
            <elementText elementTextId="496192">
              <text>Papel</text>
            </elementText>
          </elementTextContainer>
        </element>
      </elementContainer>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496182">
                <text>&lt;strong&gt;Piracetam : an&amp;aacute;lisis&lt;/strong&gt;</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496183">
                <text>&lt;strong&gt;PIRACETAM&lt;/strong&gt;</text>
              </elementText>
              <elementText elementTextId="496184">
                <text>&lt;strong&gt;QUIMICA ANALITICA&lt;/strong&gt;</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="496185">
                <text>Biblioteca-FQ</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496186">
                <text>1989</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496187">
                <text>Papel</text>
              </elementText>
              <elementText elementTextId="496188">
                <text>PDF</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496189">
                <text>Ingl&amp;eacute;s</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496190">
                <text>Bibliograf&amp;iacute;a</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="116">
            <name>Temporal Coverage</name>
            <description>Temporal characteristics of the resource.</description>
            <elementTextContainer>
              <elementText elementTextId="496191">
                <text>1984-1989</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
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    <tagContainer>
      <tag tagId="5907">
        <name>Piracetam</name>
      </tag>
      <tag tagId="3978">
        <name>Química  analítica</name>
      </tag>
    </tagContainer>
  </item>
  <item itemId="5459" public="1" featured="1">
    <fileContainer>
      <file fileId="13012">
        <src>https://riquim.fq.edu.uy/files/original/a6c8697507a1139bd848fde3a56b0e48.jpg</src>
        <authentication>0b26cd280b1337ed5c1b2e50566bda7c</authentication>
        <elementSetContainer>
          <elementSet elementSetId="5">
            <name>Omeka Image File</name>
            <description>The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files.</description>
            <elementContainer>
              <element elementId="74">
                <name>Bit Depth</name>
                <description/>
                <elementTextContainer>
                  <elementText elementTextId="496234">
                    <text>8</text>
                  </elementText>
                </elementTextContainer>
              </element>
              <element elementId="75">
                <name>Channels</name>
                <description/>
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                    <text>3</text>
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                </elementTextContainer>
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              <element elementId="73">
                <name>Height</name>
                <description/>
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                    <text>84</text>
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                </elementTextContainer>
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              <element elementId="72">
                <name>Width</name>
                <description/>
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                    <text>146</text>
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      <name>Document</name>
      <description>A resource containing textual data.  Note that facsimiles or images of texts are still of the genre text.</description>
      <elementContainer>
        <element elementId="7">
          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
          <elementTextContainer>
            <elementText elementTextId="496253">
              <text>Papel</text>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
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                <text>&lt;strong&gt;Clorofluorocarbonos : utilizaci&amp;oacute;n en aerosoles, da&amp;ntilde;os ecol&amp;oacute;gicos&lt;/strong&gt;</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>&lt;strong&gt;CLOROFLUOROCARBONOS&lt;/strong&gt;</text>
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              <elementText elementTextId="496242">
                <text>&lt;strong&gt;AEROSOLES&lt;/strong&gt;</text>
              </elementText>
              <elementText elementTextId="496243">
                <text>&lt;strong&gt;EFECTOS AMBIENTALES&lt;/strong&gt;</text>
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          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="496244">
                <text>Biblioteca-FQ</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
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                <text>1989</text>
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            </elementTextContainer>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496246">
                <text>Papel</text>
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              <elementText elementTextId="496247">
                <text>PDF</text>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="496248">
                <text>Ingl&amp;eacute;s</text>
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              <elementText elementTextId="496249">
                <text>Franc&amp;eacute;s</text>
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              <elementText elementTextId="496250">
                <text>Espa&amp;ntilde;ol</text>
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            <description>The nature or genre of the resource</description>
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                <text>Bibliograf&amp;iacute;a</text>
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            <name>Temporal Coverage</name>
            <description>Temporal characteristics of the resource.</description>
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                <text>1969-1992</text>
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        <name>Aerosoles</name>
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      <tag tagId="6041">
        <name>Clorofluorocarbonos</name>
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      <tag tagId="1301">
        <name>Efectos ambientales</name>
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  </item>
</itemContainer>
