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                <text>&lt;strong&gt;New Pd&amp;ndash;Fe ferrocenyl antiparasitic compounds with bioactive 8-hydroxyquinoline ligands:&amp;nbsp;a comparative study with their Pt&amp;ndash;Fe analogues&amp;dagger;&lt;/strong&gt;</text>
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                <text>&lt;p&gt;In the search for a more effective chemotherapy for the treatment of Human African Trypanosomiasis, a disease caused by the parasite Trypanosoma brucei, the development of ferrocenyl compounds has arisen as a promising strategy. In this work, five new Pd&amp;ndash;Fe heterobimetallic [PdII(L)(dppf)](PF6) compounds, including 8-hydroxyquinolyl derivatives HL1&amp;ndash;HL5 as bioactive ligands and dppf = 1,1&amp;rsquo;-bis(diphenylphosphino)&lt;br /&gt;ferrocene as the organometallic co-ligand, were synthesized and fully characterized in the solid state and in solution. Molecular structures of three compounds were solved by single crystal X-ray diffraction methods. The compounds displayed submicromolar or micromolar IC50 values against bloodstream&lt;br /&gt;T. brucei (IC50: 0.33&amp;ndash;1.2 &amp;mu;M), and good selectivity towards the pathogen (SI: 4&amp;ndash;102) with respect to mammalian macrophages (cell line J774). The new Pd complexes proved to be 2-fold to 45-fold more potent than the drug nifurtimox but most of them are less active than their Pt analogues. Potential molecular&lt;br /&gt;targets were studied. The complexes interact with DNA but they do not alter the intracellular thiolredox homeostasis of the parasite. In order to understand and predict the main structural determinants on the anti-T. brucei activity, a search of quantitative structure&amp;ndash;activity relationships (QSAR) was performed including all the [M(L)(dppf)](PF6) complexes, where M = Pd(II) or Pt(II), currently and previously&lt;br /&gt;developed by us. The correlation obtained shows the relevance of the electronic effects, the lipophilicity and the type of metal. According to the QSAR study, compounds with electron-withdrawing ligands, higher lipophilicity and harboring Pt would result in higher T. brucei cytotoxicity. From the whole series of&lt;br /&gt;[M(L)(dppf)](PF6) compounds developed, where M = Pt(II) or Pd(II) and HL = 8-hydroxyquinolyl derivatives, Pt-dppf-L4 (IC50 = 0.14 &amp;mu;M, SI = 48) was selected to perform an exploratory pre-clinical study in infected mice. This hit compound lacks acute toxicity when applied to animals in the dose/regimen described and exerts an anti-proliferative effect on parasites, which extends animal survival but is not curative.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Rivas, Feriannys&lt;/strong&gt;</text>
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                <text>Dalton Transactions,&amp;nbsp;v. 50, n&amp;deg; 5, 2021.-- pp. 1651-1665.</text>
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                <text>&lt;span&gt;Royal Society of Chemistry&lt;/span&gt;</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;span id="docs-internal-guid-5f57212c-7fff-3d1c-767a-ce955880e4d4"&gt;&lt;span&gt;10.1039/d0dt03963b&amp;nbsp; &lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Application of pillared raw clay-base catalysts and natural solar radiation for water decontamination by the photo-Fenton process&lt;/strong&gt;</text>
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                <text>ARCILLA</text>
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                <text>&lt;p&gt;This study presents a novel application of the heterogeneous solar photo-Fenton process using an iron-pillared clay (Fe-PILC) as a photocatalyst under natural sunlight. The Fe-PILC is characterized by thermogravimetric analysis, EDXRF, SEM and nitrogen adsorption&amp;ndash;desorption isotherms. The solar photo-reactor consists of a tubular borosilicate tube with a compound parabolic collector (CPC) and two different materials as reflective material for performance comparison. Phenol is used as model pollutant. The catalytic tests are monitored by the&lt;br /&gt;concentration of the pollutant, intermediates and the iron leaching, as well as the accumulated energy during the reaction time. Complementary catalytic tests allowed to establish the influence of parallel processes that could contribute to phenol removal. Experimental data proved that the Fe-PILC is active as heterogenous catalyst in photo-Fenton like processes promoted by natural solar radiation. The catalyst showed good stability in the process and allowed a 99%+ removal of the pollutant and its intermediates. Fenton, photolysis and adsorption do not contribute significantly to phenol removal. Finally, when comparing different reflective materials in the CPC, the aluminium sheet proved to be more efficient than the polyester film metallized with aluminium.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Rodr&amp;iacute;guez, Mayra&lt;/strong&gt;</text>
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                <text>Separation and Purification Technology,&amp;nbsp;v. 259, 2021. - e118167</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Muchas industrias generan un gran volumen de aguas residuales que contienen col-orantes, los cuales son compuestos t&amp;oacute;xicos y recalcitrantes. El objetivo principal de este estudiofue examinar la capacidad bioadsortiva de la biomasa de la levadura ant&amp;aacute;rtica Debaryomyceshansenii F39A, en presencia de los colorantes azul reactivo 19 y rojo reactivo 141. Se estudiaronalgunas variables del proceso, incluyendo el pH, la concentraci&amp;oacute;n de colorante y de adsorbenteutilizada y el tiempo de contacto. La capacidad de adsorci&amp;oacute;n se increment&amp;oacute; al aumentar laconcentraci&amp;oacute;n del adsorbato hasta 350 mg/L. Los datos de las isotermas obtenidas experimen-talmente se ajustaron con el modelo de Langmuir, donde la capacidad m&amp;aacute;xima de adsorci&amp;oacute;n(Qm&amp;aacute;x) para ambos colorantes se encuentra dentro del rango 0,0676-0,169 mmol/g de biomasa.A una concentraci&amp;oacute;n inicial de 100 mg/L de adsorbato en presencia de 2 g/L de adsorbente a20 ? 1 ?C y un valor de pH = 6, D. hansenii F39A fue capaz de adsorber aproximadamente un 90%del rojo reactivo 141 y un 50% del azul reactivo 19. Cuando la concentraci&amp;oacute;n de biomasa seincrement&amp;oacute; (6 g/L), la remoci&amp;oacute;n del azul reactivo 19 alcanz&amp;oacute; el 90%. El proceso de adsorci&amp;oacute;npara cada colorante sigue una cin&amp;eacute;tica de pseudo segundo orden. D. hansenii tiene el potencialde remover eficientemente los colorantes estudiados, a trav&amp;eacute;s de un proceso de bioadsorci&amp;oacute;ny puede considerarse una alternativa a otros materiales adsorbentes de mayor costo.</text>
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                <text>Revista Argentina de Microbiologia,&amp;nbsp;v. 53,n&amp;deg; 3, 2021. -- pp. 257-265</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;p&gt;The genus Echinococcus of cestode parasites includes important pathogens of humans and livestock animals.&lt;br /&gt;Transcriptomic and genomic studies on E. granulosus and E. multilocularis uncovered striking expansion of monodomain Kunitz proteins. This expansion is accompanied by the specialization of some family members away from the ancestral protease inhibition function to fulfill cation channel blockade functions. Since cation channels are involved in immune processes, we tested the effects on macrophage physiology of two E. granulosus Kunitztype inhibitors of voltage-activated cation channels (Kv) that are close paralogs. Both inhibitors, EgKU-1 and EgKU-4, inhibited production of the Th1/Th17 cytokine subunit IL-12/23p40 by macrophages stimulated with&lt;br /&gt;the TLR4 agonist LPS. In addition, EgKU-4 but not EgKU-1 inhibited production of the inflammatory cytokine IL-&lt;br /&gt;6. These activities were not displayed by EgKU-3, a family member that is a protease inhibitor without known&lt;br /&gt;activity on cation channels. EgKU-4 potently inhibited macrophage proliferation in response to M-CSF, whereas EgKU-1 displayed similar activity but with much lower potency, similar to EgKU-3. We discuss structural differences, including a heavily cationic C-terminal extension present in EgKU-4 but not in EgKU-1, that may explain the differential activities of the two close paralogs.&lt;/p&gt;</text>
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                <text>&lt;p&gt;Thione S-methylide, parent species of the thiocarbonyl ylide family, is a 1,3-dipolar species on the [C2SH4] potential energy surface, not so much studied as its isomers, thiirane, vinyl thiol, and thioacetaldehyde. The conrotatory ring-closure reaction toward thiirane was studied in the 90s, but no complete analysis of the potential energy surface is available. In this paper, we report a computational study of the reaction scheme linking all species. We employed several computational methods (density functional theory, CCSD(T) composite schemes, and CASSCF/CASPT2 multireference procedures) to find the best description of thione S-methylide, its isomers, and transition states. The barrier from thiirane to thione Smethylide amounts to 52.2 kcal mol&amp;minus;1 (against 17.6 kcal mol&amp;minus;1 for the direct one), explaining why thiocarbonyl ylides cannot be prepared from thiiranes. Conversion of thiirane to vinyl thiol implies a large barrier, supporting why the reaction has been observed only at high temperatures.&lt;br /&gt;Fragmentations of thiirane to S(3P) or S(1D) and ethylene as well as decomposition to hydrogen sulfide plus acetylene were also explored. Triplet and singlet open-shell species were identified as intermediates in the fragmentations, with energies lower than the transition state between thiirane and vinyl thiol, explaining the preference of the latter at low temperatures.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Materiales microporosos basados en tierras raras con potencial aplicaci&amp;oacute;n en dispositivos electr&amp;oacute;nicos&lt;/strong&gt;</text>
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                <text>&lt;p&gt;QUIMICA INORGANICA&lt;/p&gt;</text>
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                <text>MATERIALES POROSOS</text>
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                <text>&lt;p&gt;os pol&amp;iacute;meros de coordinaci&amp;oacute;n metal-org&amp;aacute;nicos (MOFs) son un tipo de material poroso sumamente vers&amp;aacute;til en cuanto al rango de aplicaciones posibles. Los MOFs se forman a partir del ensamblaje entre centros met&amp;aacute;licos y ligandos org&amp;aacute;nicos en una red tridimensional. Las propiedades del MOF en cuesti&amp;oacute;n&lt;br /&gt;dependen del centro met&amp;aacute;lico, el ligando, el tipo de conexi&amp;oacute;n, la estructura tridimensional, la morfolog&amp;iacute;a, entre otros factores. La inmensidad de posibles arreglos ha permitido la utilizaci&amp;oacute;n de&lt;br /&gt;MOFs en diversos campos de aplicaci&amp;oacute;n, desde la adsorci&amp;oacute;n y separaci&amp;oacute;n de gases, hasta la fotocat&amp;aacute;lisis. Siendo los MOFs materiales de elevada cristalinidad, la resoluci&amp;oacute;n de sus estructuras por m&amp;eacute;todos de difracci&amp;oacute;n es accesible, lo que permite aspirar a comprender las bases de su funcionamiento en t&amp;eacute;rmino de arreglos at&amp;oacute;micos. Este trabajo tratar&amp;aacute; de explorar dos aplicaciones en particular y sus relaciones con la estructura at&amp;oacute;mica para una familia de MOFs: la conducci&amp;oacute;n prot&amp;oacute;nica para potenciales electrolitos de celdas de combustible de baja temperatura y la generaci&amp;oacute;n de un material emisor de luz blanca a partir de tres centros lant&amp;aacute;nidos emisores.&lt;br /&gt;La tesis se centra en el estudio de una familia de MOFs heteropolinucleares de f&amp;oacute;rmula general [Ln2M3(oda)6]∙nH2O, formados a partir de un metal lant&amp;aacute;nido trivalente (Ln3+), un metal de transici&amp;oacute;n divalente (M2+) y el ligando oxidiacetato (oda2-). El ensamblaje entre los tres lleva en general a la&lt;br /&gt;formaci&amp;oacute;n de una estructura hexagonal neutra o de una red c&amp;uacute;bica ani&amp;oacute;nica con contraiones intercalados en los poros del material. Se estudiaron principalmente las series que estaban&lt;br /&gt;pr&amp;aacute;cticamente inexploradas de M = Ni y Co, en todo el rango de iones Ln. Se focaliz&amp;oacute; en los aspectos estructurales de los compuestos, sobre todo en las caracter&amp;iacute;sticas geom&amp;eacute;tricas que llevan a la obtenci&amp;oacute;n de un polimorfo preferencial en funci&amp;oacute;n de los metales M y Ln. Se propuso un modelo en el cual se define un factor de tolerancia en funci&amp;oacute;n de los radios i&amp;oacute;nicos de los metales, con el objetivo de explicar y predecir el tipo de estructura esperada. Se puso a prueba el factor definido frente a un sistema binario en la posici&amp;oacute;n M: [Yb2NixCo3-x(oda)6]∙nH2O. Se caracterizaron por medio de difracci&amp;oacute;n&lt;br /&gt;de polvo diferentes muestras con distinto grado de sustituci&amp;oacute;n.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?f284c5114cbe816222524640b6fe6498f8e77a4156c21b45346f284b247d507da1d3fb4ee941523690ad3bf2affed7bd2a35890fc2cad47923e6ac3ed6650237" target="_blank"&gt;&lt;strong&gt;Igoa Salda&amp;ntilde;a, Fernando&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Montevideo : UdelaR-Facultad de Qu&amp;iacute;mica</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>Espa&amp;ntilde;ol</text>
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        <name>Materiales porosos</name>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                <text>&lt;strong&gt;Development of a methodology for the aimultaneous analysis of multiclass contaminants in milk.&lt;/strong&gt;</text>
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                <text>LECHE</text>
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                <text>RESIDUOS DE PESTICIDAS</text>
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                <text>AFLATOXINAS</text>
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                <text>ESPECTROMETRIA DE MASAS</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2021</text>
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                <text>&lt;p&gt;A simple methodology for the simultaneous determination of 67 pesticides, 25 veterinary drugs, and aflatoxin M1 in raw milk&lt;br /&gt;was developed and validated. After evaluating different combinations of sample preparation protocols, an extraction with acetonitrile:water (2:1) with QuEChERS citrate buffer salts and a combination of RP-C18 and anhydrous magnesium sulfate&lt;br /&gt;for the dispersive clean-up, using gas and liquid chromatography couples to mass spectrometry for determination, was selected. Recovery percentages were between 70 and 120%, with relative standard deviations below 20% at 5, 20, and 50 &amp;mu;g kg&amp;minus;1. Aflatoxin M1 was recovered in the range 66 to 88% at 0.05, 0.1, and 0.5 &amp;mu;g kg&amp;minus;1 with relative standard deviation between 8 and 11%. The quantification limits for all the analytes with the exception of diclofenac were below their respective maximum residue&lt;br /&gt;limits. The method was applied for the analysis of 20 commercial samples, some of which showed at least one contaminant below their maximum residue limits.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Souza, Rodrigo&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Fern&amp;aacute;ndez, Paula&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Muela, Agustina&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Heinzen, Horacio&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pareja, Lucia&lt;/strong&gt;</text>
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                <text>Food Analytical Methods,&amp;nbsp;v. 14, n&amp;deg; 6, 2021. -- pp. 1075-1086.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;span id="docs-internal-guid-367f02cd-7fff-907a-653f-9697c6ae8807"&gt;&lt;span&gt;10.1007/s12161-020-01953-7 &lt;/span&gt;&lt;/span&gt;</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                <text>&lt;strong&gt;Light modulates important physiological features of Ralstonia pseudosolanacearum during the colonization of tomato plants&lt;/strong&gt;</text>
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                <text>TOMATES</text>
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                <text>ENFERMEDADES DE LAS PLANTAS</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2021</text>
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                <text>&lt;p&gt;Ralstonia pseudosolanacearum GMI1000 (Rpso GMI1000) is a soil-borne vascular phytopathogen that infects host plants through the root system causing wilting disease in a wide range of agroeconomic interest crops, producing economical losses. Several features contribute to the full bacterial virulence. In this work we study the participation of light, an important environmental factor, in the regulation of the physiological attributes and infectivity of Rpso GMI1000. In silico analysis of the Rpso genome revealed the presence of a Rsp0254 gene, which encodes a putative blue light LOV-type photoreceptor. We constructed a mutant strain of Rpso lacking the LOV protein and found that the loss of this protein and light, influenced characteristics involved in the pathogenicity process such as&lt;br /&gt;motility, adhesion and the biofilms development, which allows the successful host plant colonization, rendering bacterial wilt. This protein could be involved in the adaptive responses to environmental changes. We demonstrated that light sensing and the LOV protein, would be used as a location signal in the host plant, to regulate the expression of several virulence factors, in a time and tissue dependent way. Consequently, bacteria could use an external signal and Rpsolov gene to know their location within plant tissue during the colonization process.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Tano, Josefina&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Ripa, Mar&amp;iacute;a Bel&amp;eacute;n&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Piskulic, Laura&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Orellano, Elena Graciela&lt;/strong&gt;</text>
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                <text>Scientific Reports,&amp;nbsp;&amp;nbsp;v. 11, n&amp;deg; 1, 2021. -- e14531</text>
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                <text>Springer</text>
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                <text>2021</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
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              <elementText elementTextId="619087">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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                <text>PDF</text>
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                <text>Ingl&amp;eacute;s</text>
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            <name>Type</name>
            <description>The nature or genre of the resource</description>
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                <text>Art&amp;iacute;culo</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>&lt;span id="docs-internal-guid-2ea50dbd-7fff-02d5-b45b-77c888238272"&gt;&lt;span&gt;10.1038/s41598-021-93871-9&amp;nbsp; &lt;/span&gt;&lt;/span&gt;</text>
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        <name>Bacterias</name>
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        <name>Enfermedades de las plantas</name>
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        <name>Tomates</name>
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                <name>Height</name>
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                    <text>250</text>
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                    <text>208</text>
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            <element elementId="50">
              <name>Title</name>
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                <elementText elementTextId="709185">
                  <text>Tesis de doctorado, maestría, trabajos de diploma y monografías técnicas</text>
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              <name>Description</name>
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                  <text>Versiones electrónicas de las tesis de doctorado, maestría y trabajos de diploma de la Facultad de Química, Universidad de la República (UdelaR).&#13;
Incluye únicamente trabajos hasta el año 2023. Los trabajos posteriores se encuentran disponibles en el Repositorio Colibrí.</text>
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                  <text>Departamento de Documentación y Biblioteca</text>
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                  <text>RIQUIM</text>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>Papel</text>
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            <name>Title</name>
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                <text>&lt;strong&gt;Strategies to reduce the sugar content of dairy products targeted at children&lt;/strong&gt;</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>TESIS DE DOCTORADO</text>
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                <text>EVALUACION SENSORIAL</text>
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                <text>LACTEOS</text>
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                <text>REDUCCION DE AZUCAR</text>
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                <text>NUTRICION INFANTIL</text>
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                <text>Children&amp;rsquo;s sugar intake has raised concern worldwide as it exceeds nutritional recommendations. Although sugars are naturally present in food, sugars added to foods during industrial processing are currently the main source of sugar in children's diets. In particular, dairy products, which are generally recommended to be part of children diets, have drawn attention due to their high content of sugar. In this context, the main objective of this thesis was to explore different sugar reduction strategies in dairy products targeted at children. Results showed that sugar reduction of dairy products targeted at children available in the Uruguayan marketplace is possible. A direct sugar reduction up to 25% did not have a significant impact on children hedonic perception in three dairy products. Meanwhile the use of taste-odor-texture cross-modal interactions allowed to minimize the impact of sugar reduction on the sensory characteristics of dairy desserts. Co-creation with children was identified as a feasible approach to develop innovative healthy dairy products with high acceptance among children. Finally, package information influenced parent&amp;rsquo;s healthiness perception and choice of snacks for their children, stressing that packaging regulations should play a key role as part of the comprehensive set of strategies that should be implemented to reduce children's sugar intake. Overall, results from this work provide useful insights to food scientists for the development of sugar reduced products targeted at children, as well as valuable information for policy makers to design programs to reduce children&amp;rsquo;s sugar intake at population level.</text>
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                <text>&lt;strong&gt;Vel&amp;aacute;zquez Mendoza, Ana Laura&lt;/strong&gt;</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>&lt;span&gt;Montevideo : UdelaR-Facultad de Qu&amp;iacute;mica&lt;/span&gt;</text>
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                <text>2021</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?e41ee09b825f22635cb8a1e9b42b334d75d1c2be0ccaad4f086d148a0ebac442b4a82cfb05ef977a8fe31965e28ee4bb8889f1ccb549f56f20a9403e2c02a0cf" target="_blank"&gt;&lt;strong&gt;Ares, Gast&amp;oacute;n&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?e13bee77c03cddbef59b397e314055a6622de73c70417f3162757bfad754bfa8ad01125204736ed535ca050230cfa514a6e43d3d2464b7fea2cb77f4995d0c4b" target="_blank"&gt;&lt;strong&gt;Vidal, Leticia&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Varela, Paula&lt;/strong&gt;</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="619211">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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              <elementText elementTextId="619212">
                <text>PDF</text>
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                <text>Papel</text>
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                <text>&lt;strong&gt;Rizobacterias aisladas de Jatropha curcas L.: actividad antagonista de fitopat&amp;oacute;genos y promotora del crecimiento de plantas&lt;/strong&gt;</text>
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                <text>CURVULARIA LUNATA</text>
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                <text>&lt;p&gt;Introducci&amp;oacute;n: Jatropha curcas L. es una especie nativa de M&amp;eacute;xico que recientemente se ha considerado un cultivo importante para la producci&amp;oacute;n de biocombustible.&lt;/p&gt;&#13;
&lt;p&gt;Objetivo: Aislar e identificar rizobacterias de J. curcas con actividad antag&amp;oacute;nica frente a hongos fitopat&amp;oacute;genos (Curvularia lunata y Fusarium equiseti) del cultivo y evaluar la capacidad de estas para promover el crecimiento de plantas de jitomate.&lt;/p&gt;&#13;
&lt;p&gt;Materiales y m&amp;eacute;todos: Las cepas bacterianas se obtuvieron por diluci&amp;oacute;n en serie. La actividad antag&amp;oacute;nica se evalu&amp;oacute; mediante compuestos vol&amp;aacute;tiles y difusibles en medio de cultivo PDA; adem&amp;aacute;s, se determin&amp;oacute; la producci&amp;oacute;n de compuestos antif&amp;uacute;ngicos y metabolitos que promueven el crecimiento de plantas. Las cepas se identificaron mediante la amplificaci&amp;oacute;n de los genes ARNr 16S y sodA; posteriormente, se inocularon en semillas de jitomate para evaluar la germinaci&amp;oacute;n de las plantas y la promoci&amp;oacute;n del crecimiento.&lt;/p&gt;&#13;
&lt;p&gt;Resultados y discusi&amp;oacute;n: Las bacterias antagonistas se identificaron como Bacillus mojavensis, Bacillus subtilis, Bacillus thuringiensis y Pseudomonas aeruginosa. El efecto antif&amp;uacute;ngico sobre el crecimiento micelial de C. lunata y F. equiseti se debi&amp;oacute; a la presencia de compuestos vol&amp;aacute;tiles y difusibles con inhibici&amp;oacute;n de entre 30 % y 79 %. Pseudomonas aeruginosa mostr&amp;oacute; el efecto inhibitorio m&amp;aacute;s fuerte (48.7 a 79.8 %). Bacillus subtilis (A1), B. mojavensis (A4) y B. thuringiensis (A6, A8) mostraron la mayor germinaci&amp;oacute;n (70 % a 88 %). El crecimiento de las plantas de jitomate tratadas con cepas bacterianas fue significativamente mayor (P &amp;lt; 0.05) que el de las plantas testigo.&lt;/p&gt;&#13;
&lt;p&gt;Conclusi&amp;oacute;n: Ocho aislados de rizobacterias de J. curcas mostraron actividad antag&amp;oacute;nica frente a C. lunata y F. equiseti, y demostraron su capacidad para mejorar la germinaci&amp;oacute;n y promover el crecimiento de las plantas de jitomate.&lt;/p&gt;&#13;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Pe&amp;ntilde;a Chora, Guadalupe&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Vel&amp;aacute;zquez del Valle, Miguel G.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Hern&amp;aacute;ndez Lauzardo, Ana N.&lt;/strong&gt;</text>
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                <text>Revista Chapingo, Serie Ciencias Forestales y del Ambiente,&amp;nbsp;v. 27, n&amp;deg; 2, 2021. -- pp. 181-198.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;span id="docs-internal-guid-dcb7463e-7fff-98ec-b979-6f6f547ec0d5"&gt;&lt;span&gt;10.5154/R.RCHSCFA.2020.04.029 &lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;Catalytic oxidation is considered one of the best methods to remove volatile organic compounds. One of the main&lt;br /&gt;advantages of catalytic combustion is the low emissions of minor contaminants released to the atmosphere and low operative cost, followed by high removal properties for pollutants, compared to adsorption and incineration.&lt;br /&gt;The purpose of this paper is to review the behaviour of a group of catalysts extracted mainly from the location of Cerro Largo (Ba&amp;tilde;nado de Medina), Uruguay, through evaluation of the total combustion of toluene. The montmorillonite was pillared with a polycation of Al13, with a Keggin-like structure using conditions to ensure a molar ratio OH&lt;/p&gt;</text>
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Tunable and sizeable band gaps in strained SiC3/hBN vdW heterostructures:&amp;nbsp;a potential replacement for graphene in future nanoelectronics&lt;/strong&gt;</text>
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                <text>&lt;p&gt;In this work, we perform first-principles density functional theory calculations to study siligraphene (SiC3)/ hexagonal boron nitride (hBN) vdW-heterostructures. Siligraphene has comparable electronic properties to graphene, including the presence of a Dirac-like cone, thus we investigate its potential as a replacement for graphene. We find that, when internal strains induced by the high lattice mismatch between the SiC3 and hBN layers are reduced, a very small and non-tunable gap is induced in a hybrid bilayer heterostructure. However, the&lt;br /&gt;picture becomes quite different when structures with higher internal strains are considered. In this scenario, the&lt;br /&gt;compressive strain induces a buckling in the SiC3 sheet, resulting in larger band gaps. Additionally, in many configurations, the gaps are found to be quite tunable by the application of external strains or an electrical field. Such tunability is absent in graphene/hBN heterostructures, thus giving SiC3/hBN heterostructures a clear edge. The origin of this gap and its tunability are discussed in terms of the buckling in the SiC3 layer and the interlayer charge transfer. Finally, the optical properties of these heterostructures were also investigated. Strong absorption peaks in both visible and deep UV regions were found, which could be explored for applications in future optoelectronic devices.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?5838628233fef1a83df67e2235d927c4a69fd08d7b3b2cbd45f825b3b0327f2f869df055be96ee401aec1ab3995b9905c1339dbf8b5b1059582d0221c61fa4ea" target="_blank"&gt;&lt;strong&gt;Denis, Pablo A.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Computational Materials Science,&amp;nbsp;v. 188, 2021. --e110233</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Biocompatibility in ternary fermentations with lachancea thermotolerans, other Non-Saccharomyces and Saccharomyces cerevisiae to control pH and improve the sensory profile of wines from warm areas&lt;/strong&gt;</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2021</text>
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                <text>Global warming is causing serious problems, especially, in warm regions, where musts with excess sugars and high pH produce wines with decreased freshness and unstable evolution. This study aimed to determine biocompatibility between yeast species, the capacity for microbiological acidification, and the aromatic profile produced in ternary fermentations in which Lachancea thermotolerans has been co-inoculated with Hanseniaspora vineae, Torulaspora delbrueckii, or Metschnikowia pulcherrima, and the fermentation process is subsequently completed with sequential inoculation of Saccharomyces cerevisiae. For this purpose, different cell culture media and instruments were used such as infrared spectroscopy, enzymatic autoanalyzer, chromatograph coupled with a flame ionization detector, spectrophotometric analysis, among others. The behavior of these yeasts was evaluated alone and in co-inoculation, always finishing the fermentation with sequential inoculation of S. cerevisiae, at a stable temperature of 16&amp;deg;C and with a low level of sulfites (25 mg/L) in white must. Significant results were obtained in terms of biocompatibility using population counts (CFU/ml) in differential plating media that permitted monitoring. Quantification of the five species was studied. Concerning acidification by L. thermotolerans in co-inoculations, we showed some metabolic interactions, such as the inhibition of acidification when H. vineae/L. thermotolerans were used, generating just over 0.13 g/L of lactic acid and, conversely, a synergistic effect when M. pulcherrima/L. thermotolerans were used, achieving 3.2 g/L of lactic acid and a reduction in pH of up to 0.33. A diminution in alcohol content higher than 0.6% v/v was observed in co-inoculation with the L. thermotolerans/M. pulcherrima yeasts, with total sugar consumption and very slow completion of fermentation in the inoculations with H. vineae and T. delbrueckii. The aromatic composition of the wines obtained was analyzed and a sensory evaluation conducted, and it was found that both L. thermotolerans and co-inoculations&amp;nbsp;retained more aromatic esters over time and had a lower evolution toward the yellow tones typical of oxidation and that the best sensory evaluation was that of the Lt + Mp co-inoculation. Lachancea thermotolerans and co-inoculations produced wines with low levels of volatile acidity (&amp;lt;0.4 g/L). This work shows that good consortia strategies with binary and ternary fermentations of yeast strains can be a powerful bio-tool for producing more complex wines.</text>
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                <text>&lt;strong&gt;Vaquero, Cristian&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Loira, Iris&lt;/strong&gt;</text>
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                <text>Frontiers in Microbiology,&amp;nbsp;v. 12, 2021. -- e656262</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;p&gt;A simple composite scheme is presented and benchmarked against the 38 reactions in Truhlar's HTBH38/08 and NHTBH38/08 databases. Mean unsigned deviation&lt;br /&gt;(MUD) for the complete set of 68 independent barriers is 0.40 kcal mol-1, compared to 1.31 kcal mol-1 for G4 and 1.62 kcal mol-1 for the M06-2X-D3 method. The MUD of the new scheme on the barriers in the DBH24/08 subset (12 out of the 38&lt;br /&gt;reactions in the other sets) is 0.27 kcal mol-1, better than that obtained at the expensive CCSD(T,full)/aug-cc-pCV(T+d)Z level (0.46 kcal mol-1) and comparable to the most exact (and costly) Wn calculations (MUD = 0.14 kcal mol-1). The method was further tested against a subset of reactions, for which the geometry and energies of all species were determined at the much more demanding CCSD(T)-F12//pVQZ-F12 level. The SVECV-f12 procedure on this database results in RMSE and MUD values of only 0.21 and 0.16 kcal mol-1.&lt;/p&gt;</text>
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;p&gt;CATA (check-all-that-apply) questions enjoy high popularity for sensory product characterization with consumers. Amidst extensive methodological characterization, the meaning of term citation frequency has received modest attention only,&lt;br /&gt;possibly hindering further uptake. The present research performed a more detailed exploration of the relationship between CATA responses and perceived intensity of sensory attributes. In addition, the following question was addressed:&lt;br /&gt;How many consumers are necessary to interpret differences in CATA citation proportions as a proxy of differences in perceived intensity? The present research includes new empirical data from four consumer studies conducted in New Zealand and China under central location test conditions and a re-analysis of&lt;br /&gt;one consumer study. When dealing with samples with clear differences, the percentage of consumers selecting a sensory term for describing samples tended to be linearly correlated to average intensity ratings. A median of 15 consumers was&lt;br /&gt;needed for CATA to show good linear correlations with average intensity ratings, and the minimum number of consumers needed to reach the threshold for a good correlation was generally lower than 30.&lt;/p&gt;</text>
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                <text>Journal of Sensory Studies,&amp;nbsp;v. 36, N&amp;deg; 5, 2021. -- pp. 1-8</text>
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;p&gt;Classic acetyl thioester protection/deprotection methodologies are widely used in organic synthesis, but deprotection step usually requires harsh conditions not suitable for labile substrates. In this work, a new method for thioester deprotection using a thiotransesterification approach is described. Firstly, thioglycolic acid (TGA) was identified as a good deprotecting reagent in solution. In order to develop a thiol polymer-supported reagent, TGA was anchored to a PEG-based resin through an amide bond (TG-NCOSH).&lt;br /&gt;Both homogeneous and heterogeneous approaches were conveniently carried out at room temperature, in aqueous buffer at pH 8. The mild conditions were suitable for alkyl and phenyl thioesters. Moreover labile thioesters containing thiazolidine and oxazolidine scaffolds, bearing amine, ester and&lt;br /&gt;acetal functionalities were also deprotected. The polymer-supported TGA gave better deprotection yields compared to TGA in solution, yields ranging from 61 to 90%. The feasibility of the recovery and reuse of TG-NCO-SH reagent was explored, showing it can be reused at least five times without lossing the&lt;br /&gt;activity.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?39341dbccf2067a2ebdf27cd39859aec" target="_blank"&gt;&lt;strong&gt;Villamil, Valentina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Crystal structure and magnetic study of the complex salt [RuCp(PTA)2&amp;ndash;l-CN-1jC:2jN&amp;ndash;RuCp(PTA)2]- [Re(NO)Br4(EtOH)0.5(MeOH)0.5] /&lt;/strong&gt;</text>
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                <text>&lt;p&gt;A new RuII&amp;ndash;ReII complex salt, �-cyanido-�2C:N-bis[(�5-cyclopentadienyl)bis- (3,5,7 triazaphosphaadamantane -�P)ruthenium(II)]tetrabromido(ethanol/methanol-�O)nitrosylrhenate(II), [Ru(CN)(C5H5)2(C6H12N3P)4][ReBr4(NO)-&lt;br /&gt;(CH4O)0.5(C2H6O)0.5] or [RuCp(PTA)2&amp;ndash;�-CN&amp;ndash;1�C:2�2N-RuCp(PTA)2]-[Re(NO)Br4(EtOH)0.5(MeOH)0.5] (PTA = 3,5,7-triazaphosphaadamantane) was obtained and characterized by single-crystal X-ray diffraction, elemental analysis and infrared spectroscopy. The title salt was obtained by liquid&amp;ndash;liquid&lt;br /&gt;diffusion of methanol/DMSO solutions of (NBu4)[Re(NO)Br4(EtOH)] and[(PTA)2CpRu&amp;ndash;�-CN&amp;ndash;1�C:2�2N-RuCp(PTA)2](CF3SO3). The RuII and ReII independent moieties correspond to a binuclear and mononuclear complex ion, respectively. A deep geometrical parameter analysis was performed, and no significant differences were found with earlier reports containing similar molecules. The magnetic properties were investigated in the temperature range 2.0&amp;ndash;300 K, and the complex behaves as a quasi-magnetically isolated spin doublet with weak antiferromagnetic interactions.&lt;/p&gt;</text>
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                <text>Acta Crystallographica Section E: Crystallographic Communications,&amp;nbsp;v. 77, 2021. -- pp. 749-754.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>Medicinal Chemistry Research, 2021</text>
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;p&gt;Antibiotic resistance is a major threat to global public health. &amp;beta;-lactamases, which catalyze breakdown of &amp;beta;-lactam antibiotics, are a principal cause. Metallo &amp;beta;-lactamases (MBLs) represent a particular challenge because they hydrolyze almost all &amp;beta;-lactams and to date no MBL inhibitor has been approved for clinical use. Molecular simulations can aid drug discovery, for example, predicting inhibitor complexes, but empirical&lt;br /&gt;molecular mechanics (MM) methods often perform poorly for metalloproteins. Here we present a multiscale approach to model thiol inhibitor binding to IMP-1, a clinically important MBL containing two catalytic zinc ions, and predict the binding&lt;br /&gt;mode of a 2-mercaptomethyl thiazolidine (MMTZ) inhibitor. Inhibitors were first docked into the IMP-1 active site, testing different docking programs and scoring functions on multiple crystal structures. Complexes were then subjected to molecular&lt;br /&gt;dynamics (MD) simulations and subsequently refined through QM/MM optimization with a density functional theory (DFT) method, B3LYP/6-31G(d), increasing the accuracy of the method with successive steps. This workflow was tested on two IMP-1: MMTZ complexes, for which it reproduced crystallographically observed binding, and applied to predict the binding mode of a third MMTZ inhibitor for which a complex&lt;br /&gt;structure was crystallographically intractable. We also tested a 12-6-4 nonbonded interaction model in MD simulations and optimization with a SCC-DFTB QM/MM approach. The results show the limitations of empirical models for treating these systems and indicate the need for higher level calculations, for example, DFT/MM, for reliable structural predictions. This study demonstrates a reliable computational pipeline that can be applied to inhibitor design for MBLs and other zinc-metalloenzyme systems.&lt;/p&gt;</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;p&gt;One of the biggest problems worldwide is the pollution of natural water bodies by dyes coming from effluents used in the textile industry. In the quest for novel effluent treatment alternatives, the aim of this work was to immobilize Fe(III) complexes in molecularly imprinted polymers (MIPs) to produce efficient Fenton-like heterogeneous catalysts for the green oxidative degradation of the methyl orange (MO) dye pollutant. Different metal complexes bearing commercial and low-cost&lt;br /&gt;ligands were assayed and their catalytic activity levels towards the discoloration of MO by H2O2 were assessed. The best candidates were Fe(III)-BMPA (BMPA = di-(2-picolyl)amine) and Fe(III)-NTP (NTP = 3,30,3&amp;rdquo;-nitrilotripropionic acid), displaying above 70% MO degradation in 3 h. Fe(III)-BMPA&lt;br /&gt;caused the oxidative degradation through two first-order stages, related to the formation of BMPAFe- OOH and the generation of reactive oxygen species. Only the first of these stages was detected for Fe(III)-NTP. Both complexes were then employed to imprint catalytic cavities into MIPs. The polymers showed catalytic profiles that were highly dependent on the crosslinking agent employed, with N,N-methylenebisacrylamide (MBAA) being the crosslinker that rendered polymers with optimal oxidative performance (&amp;gt;95% conversion). The obtained ion-imprinted polymers constitute cheap and robust solid matrices, with the potential to be coupled to dye-containing effluent treatment systems with synchronous H2O2 injection.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?4891bc251f76efde9a01116117d527c1" target="_blank"&gt;&lt;strong&gt;Haller, Paulina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?750e9b353a1a0eefb2ebafb09948ec8ad0aaf80f89b11beeaec5c09b63f96eaba9e18ada7bbd99aa41fb5465563fac0dc417bfd7ca15c0e1b30c90239c1b2ecb" target="_blank"&gt;&lt;strong&gt;Torres, Julia&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?4a66380a391f31c3cebb316911e1ebfd812f0fdb9e1d82ab7b2bdbaf01254ffd7849dfab6b129d8c0ae152068bb656dc52e516bb19f5ec21387308336faad237" target="_blank"&gt;&lt;strong&gt;Vila, Agustina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Polymers, v. 13, n&amp;deg; 18, 2021. -- e3127</text>
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                <text>2021</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;span id="docs-internal-guid-8ef04205-7fff-c253-d515-4c4cc6534016"&gt;&lt;span&gt;10.3390/polym13183127&lt;/span&gt;&lt;/span&gt;</text>
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                  <text>Bibliografía Nacional Química</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                  <text>Departamento de Documentación y Biblioteca</text>
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                <text>&lt;strong&gt;2-Mercaptomethyl thiazolidines (MMTZs) inhibit all Metallo-&amp;beta;- lactamase classes by maintaining a conserved binding mode&lt;/strong&gt;</text>
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                <text>ANTIBIOTICOS-RESISTENCIA</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2021</text>
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                <text>&lt;p&gt;Metallo-&amp;beta;-lactamase (MBL) production in Gram-negative&lt;br /&gt;bacteria is an important contributor to &amp;beta;-lactam antibiotic&lt;br /&gt;resistance. Combining &amp;beta;-lactams with &amp;beta;-lactamase inhibitors (BLIs) is a validated route to overcoming resistance, but MBL inhibitors are not available in the clinic. On the basis of zinc utilization and sequence, MBLs are divided into three subclasses, B1, B2, and B3, whose differing active-site architectures hinder development of BLIs capable of &amp;ldquo;crossclass&amp;rdquo; MBL inhibition. We previously described 2-mercaptomethyl thiazolidines (MMTZs) as B1 MBL inhibitors (e.g., NDM-1) and here show that inhibition extends to the clinically relevant B2 (Sfh-I) and B3 (L1) enzymes. MMTZs inhibit purified MBLs in vitro (e.g., Sfh-I, Ki 0.16 &amp;mu;M) and potentiate &amp;beta;-lactam activity against producer strains. X-ray crystallography reveals that inhibition involves direct&lt;br /&gt;interaction of the MMTZ thiol with the mono- or dizinc centers of Sfh-I/L1, respectively. This is further enhanced by sulfur-&amp;pi;&lt;br /&gt;interactions with a conserved active site tryptophan. Computational studies reveal that the stereochemistry at chiral centers is critical, showing less potent MMTZ stereoisomers (up to 800-fold) as unable to replicate sulfur-&amp;pi; interactions in Sfh-I, largely through steric constraints in a compact active site. Furthermore, in silico replacement of the thiazolidine sulfur with oxygen (forming an oxazolidine) resulted in less favorable aromatic interactions with B2 MBLs, though the effect is less than that previously observed for the subclass B1 enzyme NDM-1. In the B3 enzyme L1, these effects are offset by additional MMTZ interactions with the protein main chain. MMTZs can therefore inhibit all MBL classes by maintaining conserved binding modes through different routes.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Hinchliffe, Philip&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Moreno, Diego M.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Rossi, Maria Agustina&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Mojica, Maria F.&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cvsni/?urlId=42fe119c34983a789c36c408f562cd5f77d193c08040c24e2c0dcd69721abe8668e45b666fbf9beae3ffd8a615c89500897f4f8242fac3b393c1234a61254446&amp;amp;convocatoria=21&amp;amp;formato=html" target="_blank"&gt;&lt;strong&gt;Martinez, Veronica&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?39341dbccf2067a2ebdf27cd39859aec" target="_blank"&gt;&lt;strong&gt;Villamil, Valentina&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Spellberg, Brad&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Drusano, George L.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Banchio, Claudia&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?11f116dbdcd0917430c764781820c3ae07133f652f4972256dc46f54fda1a3fcf8ce8ef0955ba2079acd7eb19d1ee52d88035eacfdec3666f5e20b2b35381b70" target="_blank"&gt;&lt;strong&gt;Mahler, Graciela&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Bonomo, Robert A.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Vila, Alejandro J.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Spencer, James&lt;/strong&gt;</text>
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                <text>ACS Infectious Diseases,&amp;nbsp;v. 7, n&amp;deg; 9, 2021. -- pp. 2697-2706.</text>
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                <text>American Chemical Society</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&lt;span&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;</text>
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                <text>&lt;span id="docs-internal-guid-9b5a01a0-7fff-dbe8-dcb6-45516e3cf435"&gt;&lt;span&gt;&amp;nbsp;&lt;/span&gt;&lt;span&gt;10.1021/acsinfecdis.1c00194&lt;/span&gt;&lt;/span&gt;</text>
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