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                <text>&lt;strong&gt;Facing diseases caused by Trypanosomatid parasites: rational design of Pd and Pt complexes with bioactive ligands&lt;/strong&gt;</text>
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                <text>&lt;p&gt;Human African Trypanosomiasis (HAT), Chagas disease or American Trypanosomiasis (CD), and leishmaniases are protozoan infections produced by trypanosomatid parasites&lt;br /&gt;belonging to the kinetoplastid order and they constitute an urgent global health problem. In fact, there is an urgent need of more efficient and less toxic chemotherapy for these&lt;br /&gt;diseases. Medicinal inorganic chemistry currently offers an attractive option for the rational design of new drugs and, in particular, antiparasitic ones. In this sense, one of the main&lt;br /&gt;strategies for the design of metal-based antiparasitic compounds has been thecoordination of an organic ligand with known or potential biological activity, to a metal centre or an organometallic core. Classical metal coordination complexes or organometallic compounds could be designed as multifunctional agents joining, in a single molecule, different chemical species that could affect different parasitic targets. This review is focused on the rational design of palladium(II) and platinum(II) compounds with bioactive ligands as prospective drugs against trypanosomatid parasites that has been conducted by our group during the last 20 years.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?6bb5dcce3e2559101357796ca4a2b2d4c9ba6b3a978a0bd4c5dab0107081b73e1ff46dcf49a7de2b571ff7980c4a01789f09f1d7eac1b879a8553641f940b9a5" target="_blank"&gt;&lt;strong&gt;Gambino, Dinorah&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Frontiers in chemistry v.9, 2022. -- e816266</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Unraveling post-translational modifications in Echinococcus granulosus sensu lato&lt;/strong&gt;</text>
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                <text>ECHINOCOCCUS GRANULOSUS</text>
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                <text>&lt;p&gt;Echinococcus granulosus sensu lato (s.l.) is the helminth parasite responsible for cystic echinococcosis, a neglected&lt;br /&gt;tropical disease currently affecting millions of people worldwide. Incomplete knowledge on the parasite biochemistry contributes, at least partially, to the limited development of useful biotechnological advances for the infection control. In this sense, little information is available regarding post-translational modifications (PTMs) occurring in E. granulosus s.l. proteins, which ultimately may affect the performance of biotechnological products to be developed. Therefore, we report here a proteomic analysis of the parasite PTMs identified through FindMod software applied to a set of tegumental proteins previously characterized by mass spectrometry&lt;br /&gt;(MALDI-TOF/TOF) analysis of protein spots from a 2D electrophoresis gel. Manual searches for already annotated&lt;br /&gt;proteins exhibiting such PTMs were also performed within proteome databases of E. granulosus s.l. and other platyhelminthes. In addition, key enzymes involved in PTMs modifications were searched for within E. granulosus s.l. proteome. Finally, the presence of selected PTMs was further confirmed by a high-resolution proteomic approach (nanoLC-MS/MS). A set of 22 different PTMs most likely to be present in the parasite was suggested, 9 of them with high confidence as they were identified in the same m/z fragment by both proteomic techniques (acetylation, deamidation, deamidation followed by methylation, mono- and dihydroxylation,&lt;br /&gt;mono- and di-methylation, S-nitrosylation and phosphorylation). Interestingly, 5 PTMs were herein identified for the first time in E. granulosus s.l. proteins. Our results expand the scarcely studied topic of PTMs in platyhelminthes.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Miles, Sebasti&amp;aacute;n&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?9c62cf59e616c46dd2e5eb33841818f4" target="_blank"&gt;&lt;strong&gt;Magnone, Javier&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Acta Tropica v. 230, 2022. -- 106410</text>
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                <text>Elsevier</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
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                <text>&lt;p&gt;Potential use of metal complexes in medicine is an area of&lt;br /&gt;bioinorganic chemistry that has gained much interest. Highthroughput omics approaches can provide in-depth insights&lt;br /&gt;into the mechanism of action of new metal-based compounds.&lt;br /&gt;Discovering new metallodrugs against Trypanosoma cruzi is&lt;br /&gt;an emerging field. Combining metallomics, proteomics, and&lt;br /&gt;transcriptomics allows the identification of multiple molecular&lt;br /&gt;targets and several parasitic metabolic pathways affected by&lt;br /&gt;V(IV), Pt(II), and Pd(II) potential antiparasitic drugs. Specifically, metallomics studies with Pd(II) and Pt(II) analogous compounds show higher parasite uptake of the Pt(II) than Pd(II), and both accumulate similarly in the parasite DNA&lt;br /&gt;fraction. Unexpectedly, vanadium did not associate with DNA.&lt;br /&gt;The studies reviewed illustrate the use of omics techniques for&lt;br /&gt;determining molecular targets of potential therapeutic agents.&lt;/p&gt;</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;p&gt;An experimental investigation of the structure and crystal-chemistry of the triple perovskite BaSr2MgTa2O9 is reported. Polycrystalline BaSr2MgTa2O9 was synthesized via solid-state reaction and its structure quantitatively probed at 10 and 300 K using neutron diffraction. Monoclinic (A2/m, a0 b&amp;ndash; b&amp;ndash;) and trigonal structural models (P3c1, a&amp;ndash;a&amp;ndash;a&amp;ndash;) were fit to diffraction data. The former was found to correctly reproduce experimental intensities, while the latter failed to do so. This difference is attributed to the ability of the monoclinic model to accurately reflect octahedral tilting. BaSr2MgTa2O9 features corner-sharing MgO6 and TaO6 octahedra with barium and strontium cations occupying cubooctahedral holes. Barium and strontium are disordered over the A site, whereas B site cations magnesium and tantalum are ordered. Chemical substitution of strontium for barium in Ba3MgTa2O9 induces tilting of MgO6 and TaO6 octahedra in two directions and geometric distortions&lt;br /&gt;of MgO6 octahedra.&lt;/p&gt;</text>
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                <text>&lt;p&gt;The aim of this work was to develop nanomaterials that can be used as sensitizers in radiotherapy treatment. The synthesis of bismuth sulfide (Bi2S3) particles with nanometer size by the hot injection method was studied as well as their behavior&lt;br /&gt;when coated with a biocompatible agent. The hot injection method allowed us to synthesize Bi2S3 nanorods measuring in average 4.2 &amp;plusmn; 1.4 nm in width and 27.5 &amp;plusmn; 16.3 nm in length. Moreover, to improve their biocompatibility, these nanorods were coated with polyvinylpyrrolidone with the purpose of studying the behavior of nanorods in the bloodstream. The results indicated that the suspensions were more stable when the media had protein components which may facilitate the blood circulation of the particles. The toxicity of the nanorods and their radiosensitization potential were evaluated and determined in breast cancer cells (MCF7). These results show that the synthesized nanorods did not evidence cytotoxicity up to a concentration of 2500 &amp;mu;g/mL, over 72 h of incubation. On the other hand, the sensitivity of MCF7 cells with and without nanorods in the culture medium, afterward irradiating them with a dose of 2 Gy 60Co gamma radiation source, showed a 38% increase in cell death when compared to cells that were only irradiated. Our results show that Bi2S3 nanorods are very promising as anticancer agents improving the efficiency of radiotherapy.&lt;/p&gt;</text>
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                <text>&lt;p&gt;The impact of the crystal size of the template zeolite on the textural properties of resulting Zeolite Templated Carbons was studied using nano- (20 nm) and micron-sized (5 &amp;mu;m) zeolite beta crystals. ZTCs were obtained for both nano- and micron-sized zeolite beta crystals, yet for the micron-sized sample the presence of supermicropores and small mesopores was detected, indicating a higher degree of structural defects during the templating process and hence in the final ZTC. The insights gained from nitrogen physisorption were confirmed by TEM, TGA and XPS. Despite, long range structural order, evidenced by X-ray powder diffraction (XRD) for both, nano- and micron-sized ZTCs was inferred. These results suggests that XRD patterns allow to evidence the well-ordered part of the sample but might not be the method of choice for characterizing the structural quality of ZTCs. Simulated XRD powder patterns allowed to propose a graphene-based nanoribbon structure grown in the zeolite pores as a satisfactory model for ZTCs in beta zeolite.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Improving the in vitro dissolution rate and pharmacokinetic performance of fenbendazole in sheep using drug nanocrystals&lt;/strong&gt;</text>
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                <text>NANOTECNOLOGIA</text>
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                <text>FARMACOCINETICA</text>
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                <text>&lt;p&gt;Benzimidazole methylcarbamate anthelmintics, including fenbendazole (FBZ), have only limited water solubility and small differences in drug solubility may have a major influence on their absorption, pharmacokinetic behavior and anthelmintic efficacy. To improve FBZ water solubility and dissolution rate, novel self-dispersible nanocrystals (SDNCs) of FBZ were recently described. In this work, the pharmacokinetic behavior of the SDNCs of FBZ and Poloxamer 188 was compared against a physical mixture (PM) of its components. The experiment was&lt;br /&gt;conducted following a crossover design with two different experimental phases. In phase I, sheep were treated with the SDNC (n = 3) or the PM (n = 3) formulations by the intraruminal route at the same dose rate (5 mg/kg). The treatment groups were reversed after a 7-days washout period. A non-compartmental analysis of the concentration in plasma versus time results showed that the calculated Cmax and AUC0-T were significantly higher (p &amp;lt; 0.05) for FBZ and its metabolites after the SDNC treatment compared to the PM (for FBZ: Cmax 0.346 &amp;mu;g/mL and AUC0-T 10.1 &amp;mu;g.h/mL after the SDNC vs Cmax 0.157 &amp;mu;g/mL and AUC0-T 5.1 &amp;mu;g.h/mL after the PM treatment). Additionally, population pharmacokinetic parameters of FBZ were estimated for the first time in sheep. In conclusion, the formulation of FBZ as SDNCs is a promising approach to improve FBZ dissolution reaching a higher drug plasma exposure in ruminants.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?c796a20192b2b46a2361c3b5a830c6221a1f182b4ef1ffe3563c016e66d3b47286e0a43700e2124a421846375f6ac4526255297b0590c3038b9f7b5a958b1dd2" target="_blank"&gt;&lt;strong&gt;Melian, Mar&amp;iacute;a Elisa&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?2cbeb610a8f7236c6663ee91a783afc1d6e6b222ee8d36e75a340aa3c35ca2a48ab84575006e6be42be95f4754e33e6154a54467413609e73cc060f451d018b8" target="_blank"&gt;&lt;strong&gt;Ibarra, Manuel&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Ceballos, Laura&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Paredes, Alejandro J.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Palma, Santiago&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;&amp;Aacute;lvarez, Luis Ignacio&lt;/strong&gt;</text>
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                <text>Research in Veterinary Science v. 142, 2022. -- pp. 110&amp;ndash;116</text>
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                <text>Elsevier</text>
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                <text>2022</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
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              <elementText elementTextId="639458">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>Ingl&amp;eacute;s</text>
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                <text>10.1016/j.rvsc.2021.12.001</text>
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        <name>Biodisponibilidad</name>
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        <name>Nanotecnología</name>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Bibliografía Nacional Química</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                  <text>Departamento de Documentación y Biblioteca</text>
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          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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                <text>&lt;strong&gt;Biterm topic modelling of responses to open-ended questions: a study with US consumers about vertical farming&lt;/strong&gt;</text>
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                <text>AGRICULTURA</text>
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                <text>CONSUMIDORES</text>
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                <text>COMPORTAMIENTO DEL CONSUMIDOR</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2022</text>
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                <text>&lt;p&gt;The aim of the present work was to explore the potential of Biterm Topic Modelling (BTM) for analysing responses to open-ended survey questions in the pursuit of consumer insights. The selection of BTM was based on its suitability to the analysis of short texts compared to other approaches such as Latent Dirichlet Allocation. The empirical context was vertical farming (VF), which participants read a short text about and then answered a question about interest in buying fruits and vegetables from VF. The data came from US consumers (n = 1803) who provided answers with a median length of 9 words. Results were promising about the potential of BTM to uncover latent topics from responses to open-ended questions. The models predicted coherent and consistent topics relating to VF, including buying VF produce or not and year-round fruit and vegetable supply. Two variants of the text about VF were used (n ~ 900 per variant), and BTM models trained on responses to the variant which emphasised the possibility of using genetic engineering in VF consistently predicted topics related&lt;br /&gt;to genetic engineering. Models trained on responses to the variant which emphasized urban production and reduction of carbon emissions linked to product transportation, consistently revealed topics associated to production, environment, and local farming. The major limitation was not taking account of sentiment in consumers&amp;rsquo;responses, an issue that BTM shares with other topic models. This is a significant hindrance in the efforts to rely on machine learning for consumer insights.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?e13bee77c03cddbef59b397e314055a6622de73c70417f3162757bfad754bfa8ad01125204736ed535ca050230cfa514a6e43d3d2464b7fea2cb77f4995d0c4b" target="_blank"&gt;&lt;strong&gt;Vidal, Leticia&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?e41ee09b825f22635cb8a1e9b42b334d75d1c2be0ccaad4f086d148a0ebac442b4a82cfb05ef977a8fe31965e28ee4bb8889f1ccb549f56f20a9403e2c02a0cf" target="_blank"&gt;&lt;strong&gt;Ares, Gast&amp;oacute;n&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Jaeger, Sara R.&lt;/strong&gt;</text>
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            <name>Source</name>
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                <text>Food Quality and Preferencev . 100, 2022. -- e104611</text>
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                <text>Elsevier</text>
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              <elementText elementTextId="639594">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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            <name>Language</name>
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                <text>Ingl&amp;eacute;s</text>
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                <text>10.1016/j.foodqual.2022.104611</text>
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                <text>&lt;strong&gt;The non-direct band gap in borate glasses: a brief discussion on analysis methodologies and its interpretation&lt;/strong&gt;</text>
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                <text>&lt;p&gt;There is great interest in the study of the optical properties of materials such as glasses, due to their possible technological applications and from a fundamental point of view. For this reason, an attempt has been made to advance the understanding of the existence of optical band gap in this type of material. In recent times, several ways of analyzing the dependence of the absorption coefficient with energy have been proposed. Using lead, strontium, and barium borate glasses as a model, this dependence has been analyzed. For this, we considered the glass structure and the corresponding crystal structure, and the value of the optical band gap energy has been discussed considering the theory of Mott and Davis and comparing with values of crystals and glasses of similar composition. Here, we used a correction method, that takes into account intrinsic defects, to obtain the values of optical band gap energies in the framework of a non-direct transition. We also include DFT simulations of the corresponding crystalline compounds and the band gap was evaluated. The absorption coefficient obtained from simulations shows the same trend that the experimental one.&lt;/p&gt;</text>
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                <text>Optical Materials v. 123, 2022. -- e111890</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;strong&gt;Hydrogen production via steam reforming of small organic compounds present in the aqueous fraction of bio-oil over Ni-La-Me catalysts (Me = Ce, Ti, Zr)&lt;/strong&gt;</text>
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                <text>&lt;p&gt;Biofuel production from biomass sources emerges as a promising alternative to solve the actual environmental crisis and lead to a transition to a carbon-free future. In this sense, hydrogen produced through steam reforming of a biomass-derived biofuel, such as bio-oil, appears as an interesting energetic vector. The aim of this work is the hydrogen production through steam reforming of small organic model compounds present in the aqueous fraction of bio-oil (ethanol, acetic acid, acetone) and, for a better approximation to a real system, emulate such aqueous fraction by a representative mixture of these. Ternary mixed oxides Ni-La-Me catalysts (Me = Ce, Ti, Zr) were prepared, characterized through X-ray diffraction, N2 adsorption&amp;ndash;desorption isotherms, thermogravimetric analysis, cyclic voltammetry, and scanning electron microscopy, and tested in the steam reforming reactions. Results indicate that, due to the intrinsic H2O&lt;br /&gt;adsorption capacity of ZrO2 as well to a higher number of oxygen vacancies in the catalyst structure, Ni-La-Zr presents interesting properties for its potential applicability as industrial catalyst for hydrogen production through steam reforming. On the other hand, the strong metal-support interactions on Ni-La-Ti led to a lower catalytic activity caused by a lower segregation of Ni crystallites from the mixed oxide structure.&lt;/p&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?bfc3c2407ee71cba96a714bc4de043bcbd738bacff47d0ffee4710265364e98f367f7bb9bc050f3040c58585fc26636a2c6424bf0dde8f79afb5f97e7bb680f1" target="_blank"&gt;&lt;strong&gt;Musso, Mauricio&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Mazzei, Natalia&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Decarlini, Bianca&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?5d188b2fefb96a1651cdc0802a7ed5ee5fa2dbbce24829056dd1ca7f595542893ac71231ed2ca03922171c0bef50d13345570f6eb86a1fcb3f4ff54232ef81c0" target="_blank"&gt;&lt;strong&gt;Portugau, Patrice&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Biomass Conversion and Biorefinery, 2022</text>
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            <elementTextContainer>
              <elementText elementTextId="639866">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;p&gt;A hydride generation nitrogen microwave induced plasma optical emission spectrometry (HG-MIP OES) system was developed for lead determination. Plumbane chemical generation was performed using 0.045 mol L�1 K3Fe(CN)6 as the additive in acidic medium and 2.0% w/v NaBH4 in 1% w/v NaOH as the reductant. The additivated sample and the reductant were pumped towards a cyclonic chamber where&lt;br /&gt;hydride generation and separation from the solution occurred. Operating conditions such as the additive and reductant concentration, sample, reductant and nitrogen flow-rate, the cyclonic chamber stabilization time and the viewing position in the torch were optimized. A meticulous study of the variation of the nitrogen plasma response as a function of the hydrochloric acid concentration was carried out. The analytical performance of the method was studied and its applicability evaluated in&lt;br /&gt;a Trace Element in Water Certified Reference Material and a Soil Reference Material. The method performance in terms of limits of detection and quantification (0.54 mg L�1 and 1.8 mg L�1 Pb, respectively) was found comparable to other atomic spectrometry techniques. This is to our knowledge the first research on the analytical performance of lead determination by PbH4 generation and determination by MIP OES.&lt;/p&gt;</text>
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                <text>Journal of Analitical Atomic Spectrometry, v.37, 2022. -- pp. 89-94</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;p&gt;Prostate and bladder cancers are commonly diagnosed malignancies in men. Several nitric oxide donor compounds with strong antitumor activity have been reported. Thus, continuing with our efforts to explore the chemical space around bioactive furoxan moiety, multicomponent reactions&lt;br /&gt;were employed for the rapid generation of molecular diversity and complexity. We herein report the use of Ugi and Groebke&amp;ndash;Blackburn&amp;ndash;Bienaym&amp;eacute; multicomponent reactions under efficient, safe, and environmentally friendly conditions to synthesize a small collection of nitric-oxide-releasing molecules. The in vitro antiproliferative activity of the synthesized compounds was measured against two different human cancer cell lines, LNCaP (prostate) and T24 (bladder). Almost all compounds displayed antiproliferative activity against both cancer cell lines, providing lead compounds with nanomolar GI50 values against the cancer bladder cell line with selectivity indices higher than 10.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Ingold, Mariana&lt;/strong&gt;</text>
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                <text>Molecules, 27(6)v. 27, n&amp;deg;6, 2022. --e1756</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;strong&gt;New C9-polyacetylenes from the essential oil of the highly endangered species Baccharis palustris Heering (Asteraceae)&lt;/strong&gt;</text>
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                <text>&lt;p&gt;The essential oil composition of the aerial parts from Baccharis palustris Heering (Asteraceae), a highly endangered species, was analyzed by GC/qMS, GC/HRMS-TOF, FT-IR, UV&amp;ndash;vis and NMR spectroscopy using 1D and 2D techniques. To our knowledge, this is the first report on the essential oil composition of B. palustris, as well as the first phytochemical study on this plant species. The volatile extracts were obtained from different phenologicals stages of plant, at flowering stage (FS) and vegetative stage (VS), where 51 components were identified accounting for 96.3 % and 99.0 % of the oil, respectively. The oil was rich in polyacetylene compounds (&amp;gt; 75 %), being the main components identified the new natural C9-polyacetylenes 1-nonene-3,5-diyne (1, here named as&lt;br /&gt;baccharisdiyne) (52.7&amp;ndash;65.0 %), 1,7(Z)-nonadiene-3,5-diyne [2, 7(Z)-dehydro-baccharisdiyne] (14.4&amp;ndash;17.8 %), and 1,7(E)-nonadiene-3,5-diyne [3, 7(E)-dehydro-baccharisdiyne] (1.5&amp;ndash;2.4 %). In addition, the known polyacetylenic compounds (Z)-lachnophyllum acid methyl ester (4) (4.3&amp;ndash;5.3 %) and (E)-lachnophyllum acid methyl ester (5) (0.2 %) were also identified. Moreover, GC/qMS analysis allowed the identification of other 46 components in the essential oil samples, mainly mono- and sesquiterpenoids. In B. palustris, C9-polyacetylenes&lt;br /&gt;probably derive biogenetically from a C10 precursor: baccharisdiyne (1) would be derived from either or both&lt;br /&gt;lachnophyllum methyl ester geometric isomers (4 or 5), by enzymatic hydrolysis followed by decarboxylation. Dehydro-baccharisdiynes (2 and 3) could be produced by a similar&amp;nbsp; pathway starting from the corresponding matricaria acid methyl ester isomers, one of which was tentatively identified at trace-level in B. palustris essential oil.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Umpierrez, Noelia&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Andr&amp;eacute;s Gonz&amp;aacute;lez&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?5a728c53379ba11edafc6029548ce29d65b0e495e64982b067a2707fc9d44e90fa33fc21f214f2d552656809bf896fdbcfece552c850bab35f4d18fc3812ebd9" target="_blank"&gt;&lt;strong&gt;Dellacassa, Eduardo&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Catal&amp;aacute;n, C&amp;eacute;sar A. N.&lt;/strong&gt;</text>
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                <text>Phytochemistry Letters, v. 48, 2022. -- pp. 106&amp;ndash;113</text>
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              <elementText elementTextId="640208">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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        <name>Baccharis palustris</name>
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                  <text>Bibliografía Nacional Química</text>
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                <text>&lt;strong&gt;Synthesis and antiplasmodial assessment of nitazoxanide and analogs as new antimalarial candidates&amp;nbsp;&lt;/strong&gt;</text>
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                <text>NITAZOXANIDA</text>
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                <text>TIAZOL</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2022</text>
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                <text>&lt;p&gt;During the last years, the progression to control malaria disease seems to be slowed and WHO (World Health Organization) reported a modeling analysis with the prediction of the increase in malaria morbidity and mortality in sub-Saharan Africa during the COVID-19 pandemic. A rapid way to the discovery of new drugs could be carried out by performing&lt;br /&gt;investigations to identify drugs based on repurposing of &amp;ldquo;old&amp;rdquo; drugs. The 5-nitrothiazole drug, Nitazoxanide was shown to&lt;br /&gt;be active against intestinal protozoa, human helminths, anaerobic bacteria, viruses, etc. In this work, Nitazoxanide and&lt;br /&gt;analogs were prepared using two methodologies and evaluated against P. falciparum 3D7. A bithiazole analog, showed&lt;br /&gt;attractive inhibitory activity with an EC50 value of 5.9 &amp;mu;M, low propensity to show toxic effect against HepG2 cells at&lt;br /&gt;25 &amp;mu;M, and no cross-resistance with standard antimalarials.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Irabuena, Camila&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?67d1215857f6fed1d955cefed7ee251375e8f6ebcf6c48a8320823d1f623bbe5e483326ddb2d7280e563920c8af7187a2ab8df988b943af686bc184248cd6820" target="_blank"&gt;&lt;strong&gt;Scarone, Laura&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;de Souza, Guilherme Eduardo&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Campos Aguiar, Anna Caroline&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Rossi Mendes, Giovana&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Carvalho Guido, Rafael Victorio&lt;/strong&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?ce3355fb23e003850e4fa1f06c5342b918dfd64cda25912cab59933f806ac0b8e59fe24423e4d254d567d26b057887c43b50474a1c989777b54ad95d60ba9790" target="_blank"&gt;&lt;strong&gt;Serra, Gloria&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Medicinal Chemistry Researchv. 31, 2022. -- pp. 426&amp;ndash;435</text>
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                <text>Springer</text>
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                <text>2022</text>
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            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="640337">
                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;p&gt;Despite being a preventable and curable disease, Tuberculosis (TB) is the world's top infectious killer. Development of new drugs is urgently needed. In this work, the synthesis and characterization of new silver(I) complexes, that include N&amp;prime; -[(E)-(pyridine-2-ylmethylene)pyrazine-2-carbohydrazide, HPCPH, as main ligand and substituted aryl-phosphines as auxiliary ligands, is reported. HPCPH was synthesized from pyrazinoic acid, the active metabolite of the first-line antimycobacterial drug pyrazinamide. Complexes [Ag(HPCPH)(PPh3)2]OTf (1), [Ag(HPCPH)((P(p-tolyl)3)2]OTf (2) and [Ag(HPCPH)(P(p-anisyl)3)2]OTf (3) were characterized in solid state and in solution by elemental analysis and FTIR and NMR spectroscopies (OTf&amp;ndash;&amp;ndash;triflate). Crystal structures of (1,2) were determined by XRD. The Ag atom is coordinated to azomethine and pyridine nitrogen atoms of HPCPH ligand and to the phosphorous atom of each aryl-phosphine co-ligand. Although HPCPH did not show activity, the Ag(I) compounds demonstrated activity against Mycobacterium tuberculosis (MTB), H37Rv strain, and multidrug resistant clinical isolates (MDR-TB). Globally, results showed that the compounds are not only effective against the sensitive strain, but are more potent against MDR-TB than antimycobacterial drugs used in therapy.&lt;br /&gt;The compounds showed low to moderate selectivity index values (SI) towards the bacteria, using MRC-5 cells (ATCC CCL-171) as mammalian cell model. Interaction with DNA was explored to get insight into the potential mechanism of action against the pathogen. No significant interaction was detected, allowing to discard this biomolecule as a potential molecular target. Compound 1 was identified as a hit compound (MIC90 2.23 &amp;mu;M; SI 4.4) to develop further chemical modifications in the search for new drugs.&lt;/p&gt;</text>
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                <text>Journal of Inorganic Biochemistry v. 227, 2022. -- e111683</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;p&gt;Attitude measurement occupies a central position in consumer research. Concerns over the validity and reliability of traditional measures have motivated the development of alternative approaches. The present research introduces text highlighting as a method for measurement of explicit attitudes using a case study on vertical farming (VF) with 837 UK consumers. They participated in an online survey, where they read a text about VF and used highlighting functions to mark text as &amp;lsquo;like&amp;rsquo; and &amp;lsquo;dislike.&amp;rsquo; Consumers approached the task in a systematic&lt;br /&gt;and logical way and desirable aspects of VF were frequently highlighted as &amp;lsquo;like&amp;rsquo;, whereas undesirable aspects were more frequently highlighted as &amp;lsquo;dislike&amp;rsquo;. The text highlighting responses were summarised using word clouds, frequency tables and through sentiment scores to reveal an overall positive attitude to VF among participants.&lt;br /&gt;Sentiment scores enabled the identification of consumer segments with interpretable differences in their attitude towards VF. Two approaches to method validation &amp;ndash; comparison with direct attitude questions and consumer profiling &amp;ndash; further confirmed the potential of the text highlighting method. The sentiment of specific sentences in the text highlighting task matched results from self-reported attitudinal based on Likert scales. Consumer segments with different sentiment in the text highlighting task also differed in their food technology neophobia scores in the expected direction. Future research should investigate methodological aspects of text highlighting and explore its suitability to other applications.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Jaeger, Sara R.&lt;/strong&gt;</text>
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                <text>Food Quality and Preference v. 95, 2022. -- e104356</text>
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&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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                <text>Biodiesel generated by transesterification of triglycerides from renewable sources is a clean form of energy that is currently used in many countries in blends with petrodiesel. It is mainly produced from food-grade vegetable oils obtained from oleaginous crops. High prices of these oils have made the sustainability of biodiesel production questionable. The use of nonedible feedstocks, such as intracellular triglycerides accumulated by oleaginous yeasts, appears as a feasible alternative. However, it has been demonstrated that an economically sustainable production of yeast oil could only be possible if lowcost media based on industrial subproducts, or wastes are used. In this work, we propose intracellular lipids production by a previously selected oleaginous yeast strain in a medium composed only by sugar cane vinasse and crude glycerol. Different culture strategies were studied. The highest biomass and lipid yields were obtained when the yeast R. graminis S1/2R was cultivated in batch without control of dissolved oxygen. The fatty acid methyl esters obtained under these conditions met the specification of international biodiesel standards.</text>
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                <text>World Journal of Microbiology and Biotechnology. v.38, 2022. --</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Iboga inspired N-Indolylethyl-Substituted isoquinuclidines as a bioactive scaffold: chemoenzymatic synthesis and&amp;nbsp;characterization as GDNF releasers and antitrypanosoma agents&lt;/strong&gt;</text>
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                <text>&lt;p&gt;The first stage of the drug discovery process involves the identification of small compounds with biological activity. Iboga alkaloids are monoterpene indole alkaloids (MIAs) containing a fused isoquinuclidine-tetrahydroazepine ring. Both the natural products and the iboga-inspired synthetic analogs have shown a wide variety of biological activities. Herein, we describe the chemoenzymatic preparation of a small library of novel N-indolylethyl-substituted isoquinuclidines as iboga-inspired&lt;br /&gt;compounds, using toluene as a starting material and an imine Diels&amp;ndash;Alder reaction as the key step in the synthesis. The new iboga series was investigated for its potential to promote the release of glial cell line-derived neurotrophic factor (GDNF) by C6 glioma cells, and to inhibit the growth of infective trypanosomes. GDNF is a neurotrophic factor widely recognized by its crucial role in development, survival, maintenance, and protection of dopaminergic neuronal circuitries affected in&lt;br /&gt;several neurological and psychiatric pathologies. Four compounds of the series showed promising activity as GDNF releasers, and a leading structure (compound 11) was identified for further studies. The same four compounds impaired the growth of bloodstream Trypanosoma brucei brucei (EC50&lt;br /&gt;1&amp;ndash;8 uM) and two of them (compounds 6 and 14) showed a good selectivity index.&lt;/p&gt;</text>
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&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Electronic structure properties of boron&amp;ndash;doped and carbon&amp;ndash;boron&amp;ndash;codoped TiO2(B) for photocatalytic applications&lt;/strong&gt;</text>
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                <text>A path to enhance the efficiency of photocatalytic devices is by doping the active semiconductor in order to maximize the light absorption. However, impurities could increase the recombination of photoinduced charge carriers, in order that a careful analysis on the effects of those impurities it is necessary. On this research, density functional theory calculations were applied to analyze the structure and electronic characteristics of B&amp;ndash;doped and C+B&amp;ndash;codoped TiO2(B) considering the lowest formation energy of substitutional impurities. Our calculations suggest that the swapping of a boron or carbon atom for an oxygen atom (B@O or C@O) is energetically more favorable than the replacement of titanium atoms. The obtained results seem to indicate that the boron substitution into O2C and O3C1 sites leads to its migration towards interstitial sites in both mono and codoping, thus causing a great geometrical distortion compared to pure TiO2(B). Furthermore, impurity states in the band gap were obtained after B@O doping and C+B&amp;ndash;codoping, producing an improvement of the optical properties, so it can be assumed that this nanomaterial might act as a photoelectrode after an adequate design optimization that facilitates the charge carrier separation.</text>
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&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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                <text>&lt;div&gt;Alternate bearing in citrus trees has been extensively studied as a key feature for citrus growers. Although the genetic and the biochemical process occurring during alternate bearing has been studied extensively, there is a lack of information identifying the presence of metabolic indicators during &amp;ldquo;on&amp;rdquo; and &amp;ldquo;off&amp;rdquo; years. In citrus plants, leaves play a central role in the metabolic pathway triggering the flflowering induction process. To investigate the changes during this transition, a liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) analysis of the leaf profifiles of 20 compounds (17 polyphenols, two limonoids, and one furanocoumarin), in bearing and non-bearing branches arising from four different mandarin genotypes, was performed. The same metabolites were found in all the genotypes at both stages: both limonoids and 11 polyphenols.&lt;/div&gt;&#13;
&lt;div&gt;Using these compounds, the chemotaxonomic differentiation between cultivars was assessed. The levels of flflavanones and limonoids showed differences in both bearing stages and the transition from vegetative to flflowering could be shown by the activation of the polyphenol biosynthetic pathway, from precursors like naringenin to metabolic end-points such as narirutin and polymethoxyflflavones.&lt;/div&gt;&#13;
&lt;div&gt;Narirutin levels showed signifificant differences between both stages, suggesting it as a possible marker of the physiological status of the branch.&lt;/div&gt;</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;</text>
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&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/strong&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;span id="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;strong&gt;ADVERTENCIA:&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;p style="margin-bottom: 0cm;" align="LEFT"&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-size: small;"&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;em&gt;Zingiber officinale &lt;/em&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;Rosc.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;em&gt;, &lt;/em&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: STIX, STI Extra, sans-serif;"&gt;&lt;em&gt;&amp;ldquo;&lt;/em&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;ginger&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: STIX, STI Extra, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;&amp;rdquo;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;, is widely cropped for its use as a spice and raw material for phytotherapeuticals. During cropping or post-harvest, different phytosanitary products are used, whose residues can be found in the final product, lowering the, quality and safety of the raw material. To detect those residues, a multi-contaminant methodology for GC&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: STIX, STI Extra, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;&amp;ndash;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;MS/MS analysis was developed and validated. For the selection of most suitable methodology, the performance of three methods in the determination of 39 analytes were compared: QuEChERS, QuEChERS AOAC 2007.01, and a modification of the AcOEt method, based on the inclusion of Al&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;sub&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;2&lt;/span&gt;&lt;/span&gt;&lt;/sub&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;(SO&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;sub&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;4&lt;/span&gt;&lt;/span&gt;&lt;/sub&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;)&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;sub&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;3&lt;/span&gt;&lt;/span&gt;&lt;/sub&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt; in the extraction step to form stable and ethyl acetate insoluble Aluminum- (gingerols and/or polyphenols) complexes, lowering the co-extractives load injected in the instrument. Compared to the Acetonitrile based methods, the AcOEt method showed the best performance as 95% of the targeted analytes yielded recoveries between 70 and 120 and 80% of them between 90 and 110%). The method was validated for 57 contaminant residues by GC&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: STIX, STI Extra, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;&amp;ndash;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;MS/MS. The figures of merit (media of recoveries 96% and RSD 16%, back calculated concentration &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span&gt;&lt;em&gt;&amp;lt; &lt;/em&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;20%, matrix effects &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span&gt;&lt;em&gt;&amp;gt; &lt;/em&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;100%, linearity 5&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: STIX, STI Extra, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;&amp;ndash;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;300 &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: STIX, STI Extra, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;&amp;mu;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;kg-&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;sup&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;1&lt;/span&gt;&lt;/span&gt;&lt;/sup&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;) of the method accomplished the SANTE guidelines and the LOQs for all compounds (10-25&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: STIX, STI Extra, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;&amp;mu;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;kg&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;sup&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;-1&lt;/span&gt;&lt;/span&gt;&lt;/sup&gt;&lt;/span&gt;&lt;span style="color: #000000;"&gt;&lt;span style="font-family: Charis SIL, Charis SIL, sans-serif;"&gt;&lt;span style="font-style: normal;"&gt;) were below the ginger MRLs defined by food and medicinal herbs regulations, to ensure its safe consumption. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;</text>
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                <text>Microchemical Journal. v. 175, 2022. -- e107349</text>
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&lt;p&gt;&lt;span style="font-family: Arial, sans-serif;"&gt;&lt;span style="font-size: small;"&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;&lt;span style="font-family: Arial, sans-serif;"&gt;&lt;span style="font-size: small;"&gt;La legislaci&amp;oacute;n uruguaya protege el derecho de autor&lt;/span&gt;&lt;/span&gt;&lt;/strong&gt;&lt;span style="font-family: Arial, sans-serif;"&gt;&lt;span style="font-size: small;"&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a name="docs-internal-guid-9d2103f7-7fff-c813-00c7-2528fd4891ff"&gt;&lt;/a&gt; &lt;strong&gt;&lt;span style="font-family: Arial, sans-serif;"&gt;&lt;span style="font-size: small;"&gt;ADVERTENCIA:&lt;/span&gt;&lt;/span&gt;&lt;/strong&gt;&lt;span style="font-family: Arial, sans-serif;"&gt;&lt;span style="font-size: small;"&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Consumer perspectives on the inclusion of nutritional warnings in retail food establishments&amp;nbsp;&lt;/strong&gt;</text>
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                <text>ADVERTENCIAS NUTRICIONALES</text>
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                <text>&lt;div&gt;El presente trabajo tuvo como objetivo evaluar la percepci&amp;oacute;n de los consumidores uruguayos en relaci&amp;oacute;n a la implementaci&amp;oacute;n de advertencias nutricionales en cuatro puntos de venta de comida y generar ideas sobre c&amp;oacute;mo podr&amp;iacute;a implementarse esta medida. Se realiz&amp;oacute; un estudio online con una muestra no probabil&amp;iacute;stica de 547 participantes, reclutados utilizando publicidad en redes sociales. Los participantes indicaron su grado de acuerdo con la implementaci&amp;oacute;n de advertencias nutricionales en panader&amp;iacute;as, rotiser&amp;iacute;as, lugares de venta de comida r&amp;aacute;pida y sitios de pedidos online, y proporcionaron ideas sobre c&amp;oacute;mo incluir esta inforamci&amp;oacute;n en cada punto de venta. Los resultados sugieren que la poblaci&amp;oacute;n tiene una perecpeci&amp;oacute;n positiva sobre la inclusi&amp;oacute;n de advertencias nutricionales en puntos de venta de comida. Los participantes destacaron la importancia de incluir esta informaci&amp;oacute;n en un lugar visible al momento de elegir los productos, de forma que pueda ser tenida en cuenta al tomar las decisiones. En particular, las vitrinas y la carteler&amp;iacute;a/pizarras fueron identificados como lugaresestat&amp;eacute;gicos para la inclusi&amp;oacute;n de advertencias nutricionales en panader&amp;iacute;as/rotiser&amp;iacute;as y puntos de venta de comida r&amp;aacute;pida, respectivamente. Los resultados proporcionan valiosa informaci&amp;oacute;n para extender la inclusi&amp;oacute;n de advertencias nutricionales a puntos de venta de comida.&lt;/div&gt;</text>
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                <text>&lt;a href="https://exportcvuy.anii.org.uy/cv/?7dd276e2441870ffa17f20a0b26e1c6d1f5d2bf6d0e6bdc40832dca4787f1ea7e26c717086e07a5df1b47e258b828694cf34bd7bd13348216c403d4897e7969e" target="_blank"&gt;&lt;strong&gt;Ant&amp;uacute;nez, Luc&amp;iacute;a&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Revista chilena de nutrici&amp;oacute;n v. 49, n&amp;deg;1. -- pp. 43-52</text>
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