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                <text>&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/5cdfc2a74236523967ff331970f38489.pdf" target="_blank"&gt;1 - Disposiciones repglamentarias relativas a la elaboraci&amp;oacute;n, venta e importaci&amp;oacute;n de sustancias alimenticias. -IComunicaci&amp;oacute;n del Consejo Nacional de Higiene. -IIDecreto del Consejo Nacional de Administraci&amp;oacute;n por el que se apprueban las disposiciones de referencia.&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/42be2f67f28577026ad35b5636670066.pdf" target="_blank"&gt;2 -Dereto del Poder Ejecutivo, por el que de acuerdo con lo solicitado por el Consejo N. de Higiene, se modifica el art&amp;iacute;culo 1&amp;ordm; del Decreto de 28 de julio de 1920, sobre funcionamiento de las casas denominadas &amp;ldquo;Pensiones de Artistas&amp;rdquo;.&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/3e4714eed75c6447143357ea371e7aca.pdf" target="_blank"&gt;3 - Memoria anual de los M&amp;eacute;dicos del Servicio Publico de los Departamentos de Soriano y Treinta y Tres, correspondientes al a&amp;ntilde;o 1921.&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/641513c6175c8726bdfa3d2e9b5426b3.pdf" target="_blank"&gt;4-El programa del curso de Higiene en 1922, del Profesor doctor Justo. F. Gonz&amp;aacute;lez.&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/b0fb8681df75e20fb894bed959d6346c.pdf" target="_blank"&gt;5 - &amp;lt;De la Siligraf&amp;iacute;a a la Sifilimetr&amp;iacute;a&amp;gt;, por el doctor Arthur Vernes, Director del Insitituto Profil&amp;aacute;ctico de Par&amp;iacute;s (Extracto).&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/4931c1e5fc444668cf0f47d115360749.pdf" target="_blank"&gt;6 - Necrol&amp;oacute;gica. -Farmac&amp;eacute;utico Juan Fonseca..&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/2e0329a691aaadd4fd29bc4678f1477f.pdf" target="_blank"&gt;7 - Bibliogr&amp;aacute;ficas. - Nuevo compuesto bism&amp;uacute;tico para el tratamiento de la s&amp;iacute;filis.-Sobre tuberculinizaci&amp;oacute;n de las vacas lecheras: &amp;iquest;Es necesario sacrificar las que reaccionan a la tuberculina?.- Hidatidosis, profilaxis.&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/4ae92808d8dc228a7ee5f14f6f7df6c1.pdf" target="_blank"&gt;8 - Publicaciones recibidas.&lt;/a&gt;&lt;/p&gt;&#13;
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&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/4c65d36cea77f3e59a6b4a38710a3b5d.pdf" target="_blank"&gt;10 - Consejo de Administraci&amp;oacute;n Departamental de Montevideo. - Direcci&amp;oacute;n de Salubridad. -Casa de Desinfecci&amp;oacute;n Dr. Gabriel Honor&amp;eacute;. -Servicio Bacteriolog&amp;iacute;a y Vacuna.&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/54ae9282967cf7a80f8ad481d48b4a03.pdf" target="_blank"&gt;11 - Balance del Caja del Consejo Nacional de Higiene, correspondientes al mes de agosto.&lt;/a&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;a href="http://riquim.fq.edu.uy/archive/files/b38d44d8d62d990c225031cbb31cfa07.pdf" target="_blank"&gt;12 - Cuenta complementaria de la Caja del Consejo N. de Hiegiene, correspondiente al Ejercicio econ&amp;oacute;mico 1921-922.&lt;/a&gt;&lt;/p&gt;</text>
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                <text>El trastorno por uso de sustancias es una enfermedad cr&amp;oacute;nica de graves consecuencias. Actualmente, los tratamientos farmacol&amp;oacute;gicos no apuntan a corregir los cambios neurobiol&amp;oacute;gicos generados en el cerebro por el uso cr&amp;oacute;nico de sustancias de abuso, sino que se enfocan principalmente en la atenuaci&amp;oacute;n de algunos de los s&amp;iacute;ntomas que padece el consumidor. La iboga&amp;iacute;na es un psicod&amp;eacute;lico at&amp;iacute;pico que, tanto en estudios observacionales como en ensayos cl&amp;iacute;nicos abiertos, ha mostrado una propiedad antiadictiva que perdura en el tiempo. Sin embargo, su delicado perfil de toxicidad card&amp;iacute;aca, as&amp;iacute; como su uso en entornos sin adecuadas medidas de seguridad, han limitado su progresi&amp;oacute;n en las investigaciones cl&amp;iacute;nicas. Los efectos antiadictivos de iboga&amp;iacute;na han disparado diversas l&amp;iacute;neas de investigaci&amp;oacute;n b&amp;aacute;sica, precl&amp;iacute;nica y cl&amp;iacute;nica, que buscan confirmar su efectividad, entender sus mecanismos de acci&amp;oacute;n y delimitar su perfil de seguridad. Dada la poca informaci&amp;oacute;n disponible para los profesionales de salud sobre esta sustancia, esta revisi&amp;oacute;n busca aportar informaci&amp;oacute;n acerca de su potencial terap&amp;eacute;utico, posibles mecanismos de acci&amp;oacute;n y riesgos asociados a su administraci&amp;oacute;n.</text>
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                <text>Revista de Psiquiatr&amp;iacute;a del Uruguay v.87, n&amp;deg; 1, 2023</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>The iboga alkaloids scaffold shows great potential as a pharmacophore in drug candidates for the treatment of neuropsychiatric disorders. Thus, the study of the reactivity of this type of motif is particularly useful for the generation of new analogs suitable for medicinal chemistry goals. In this article, we analyzed the oxidation pattern of ibogaine and voacangine using dioxygen, peroxo compounds, and iodine as oxidizing agents. Special focus was placed on the study of the regio- and stereochemistry of the oxidation processes according to the oxidative agent and starting material. We found that the C16-carboxymethyl ester present in voacangine stabilizes the whole molecule toward oxidation in comparison to ibogaine, especially in the indole ring, where 7- hydroxy- or 7-peroxy-indolenines can be obtained as oxidation products. Nevertheless, the ester moiety enhances the reactivity of the isoquinuclidinic nitrogen to afford C3-oxidized products through a regioselective iminium formation. This differential reactivity between ibogaine and voacangine was rationalized using computational DFT calculations. In addition, using qualitative and quantitative NMR experiments combined with theoretical calculations, the absolute stereochemistry at C7 in the 7- hydroxyindolenine of voacangine was revised to be S, which corrects previous reports proposing an R configuration.</text>
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                <text>Journal of Natural Products v. 86, n&amp;deg; 6, 2023. -- pp. 1500&amp;ndash;1511</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>The combined use of metallic nanoparticles with protective systems has made it possible to manufacture new materials with the desired properties and besides, are a class of nanostructured materials that have recently received attention due to their interesting properties and wide range of applications in catalysis, biology, materials chemistry, sensors, among others. Silver (Ag)-coated iron (Fe) nanoparticles as functional antimicrobial agents have become an important research topic. However, there are synthesis methods and important properties and characteristics that still need to be investigated. In this study, a simple synthesis route for Fe2O3-Ag nanoparticles is presented using the microemulsion reaction (MR) technique, since these systems can be applied as antimicrobial agents in biological processes and subsequently recovered through the use of a magnet. The results obtained to date demonstrate the ability to use the MR method to design and synthesize nanoparticles composed of metals that synergize their properties.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Tautomerism and rotamerism of favipiravir and halogenated analogues in solution and in the solid state&lt;/strong&gt;</text>
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                <text>Favipiravir is an important selective antiviral against RNA-based viruses, and currently, it is being repurposed as a potential drug for the treatment of COVID-19. This type of chemical system presents different carboxamide-rotameric and hydroxyl-tautomeric states, which could be essential for interpreting its selective antiviral activity. Herein, the tautomeric 3-hydroxypyrazine/3-pyrazinone pair of favipiravir and its 6-substituted analogues, 6-Cl, 6-Br, 6-I, and 6-H, were fully investigated in solution and in the solid state through ultraviolet&amp;ndash;visible, 1H nuclear magnetic resonance, infrared spectroscopy, and X-ray diffraction techniques. Also, a study of the gas phase was performed using density functional theory calculations. In general, the keto&amp;ndash;enol balance in these 3-hydroxy-2-pyrazinecarboxamides is finely modulated by external and internal electrical variations via changes in solvent polarity or by replacement of substituents at position 6. The enol tautomer was prevalent in an apolar environment, whereas an increase in the level of the keto tautomer was favored by an increase in solvent polarity and, even moreso, with a strong hydrogen-donor solvent. Keto tautomerization was favored either in solution or in the solid state with a decrease in 6-substituent electronegativity as follows: H ≫ I &amp;asymp; Br &amp;gt; Cl &amp;ge; F. Specific rotameric states based on carboxamide, &amp;ldquo;cisoide&amp;rdquo; and &amp;ldquo;transoide&amp;rdquo;, were identified for the enol and keto tautomer, respectively; their rotamerism is dependent on the tautomerism and not the aggregation state.</text>
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                <text>The Journal of Organic Chemistry v.88, n&amp;deg;15, 2023. -- pp. 10735&amp;ndash;10752</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>TRANSISTORES ELECTROQUIMICOS ORGANICOS</text>
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                <text>&lt;p&gt;Recent studies are being focused on establishing a link between structural and mixed ionic-electronic transport properties based on the characterization of organic mixed ionic-electronic conductors (OMIECs) under operation conditions in organic electrochemical transistor (OECT) devices. Here, we report the simultaneous access to microstructural, chemical, and physical information using impedance spectroscopy and micro-Raman imaging techniques to address the mixed ionic-electronic transport mechanisms in PEDOT:PSS-based OMIECs working as OECT channel materials. We focused on the out-of-plane and inplane mixed ionic-electronic transport mechanisms and complement our experimental studies with computational simulations using molecular dynamics (MD) and density functional theory (DFT) methodologies. Our studies revealed that the out-of-plane transport is based on ionic injection and diffusion mainly associated with the formation of nanopore channels in PEDOT:PSS exhibiting sulfonic groups toward the aqueous media. Thus, we also evidenced that the dedoping is not only due to the direct interaction of positive ions with PEDOT:PSS bulk region but also indirectly by the rearrangements of sulfonic groups from PSS toward the aqueous media. The in-plane transport in the OECT channel was properly described as a mixed ionic-electronic transport, with not only ionic transport of sodium (Na+) but also hydronium (H3O+) species mainly through nanopores and PEDOT:PSS bulk regions and with electronic transport mainly through the PEDOT:PSS bulk region. Although it is shown that the electronic transport monotonically declines with increasing ionic concentration, the Na+ diluted regime (1 mM) exhibits weak selectivity compared to H3O+ species, and the Na+ concentrated regime (100 mM) induces extreme porosity in PEDOT:PSS yielding to the destruction of the device. These results introduce some particular features for PEDOT:PSS-based OECT channel materials that need to be considered not only for ionic concentration and selectivity but also other related stability issues.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Mombr&amp;uacute;, Dominique&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pignanelli, Fernando&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Faccio, Ricardo&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Mombr&amp;uacute;, &amp;Aacute;lvaro W.&lt;/strong&gt;</text>
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                <text>Applied Electronic Materials, v.5. n&amp;deg;9, 2023. --</text>
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                <text>ACS Publications</text>
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                <text>&lt;div class="element-text"&gt;&#13;
&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
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                <text>Background: The body mass index (BMI) &amp;ge;30 kg/m2 is the universally accepted cut-off point for defining obesity; however, its accuracy in classifying obesity in older adults is poorly understood. Objectives: To assess the performance of the BMI cut-off point &amp;ge;30 kg/m2 in classifying obesity in older adults, using the fat mass index (FMI) and fat mass percentage (FM%) as reference criteria; and to establish region- and sex-specific BMI-based cut-off points to classify obesity in older adults. Methods: The present study is a secondary analysis derived from a cross-sectional project that included a sample of 1463 older adults from ten Latin American and Caribbean countries. Volunteers underwent total body water measurements using the deuterium dilution technique to determine FMI and FM%. Accuracy of the BMI and derived cutoff points was assessed by the area under the receiver operating characteristic curve (AUC).Results: The BMI cut-off point &amp;ge;30 kg/m2 had low sensitivity for classifying obesity in these older adults compared to the FMI and FM%. The AUC values for the optimal BMI-derived cut-off points showed an acceptable-to-outstanding discriminatory capacity in diagnosing obesity defined by the FMI. There was also a better balance between sensitivity and specificity than with the values obtained by a BMI &amp;ge;30 kg/m2 in older subjects in both regions. Conclusion: The BMI cut-off point &amp;ge;30 kg/m2 had poor sensitivity for accurately diagnosing obesity in older adults from two regions. The region- and sex-specific BMI-derived cut-off points for defining obesity using the FMI are more accurate in classifying obesity in older men and women subjects from both regions.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Sn-based nanocomposites attract extensive attention as a new generation of photoelectric hybrid materials due to their high photoelectric conversion efficiency. In this work we synthesized SnS2 nanoparticles by a hydrothermal method employing citric acid (capping agent) and performed a capping agent exchange by pyridine to improve their solution processing and final properties. We fabricated layers with pyridine-capped nanoparticles and poly (3-hexylthiophene-2,5-diyl) (P3HT), employing the classical partial film sequence of a solar cell (ITO/PEDOT: PSS/P3HT:Nps). We found a &amp;ldquo;coupling" between the nanoparticles and the polymer and highly ordered structures within the layers. The addition of nanoparticles improved the UV&amp;ndash;vis absorption of P3HT and allowed the exploitation of the photoluminescence emission to promote extra charge carrier generation. Moreover, we found that SnS2_py nanoparticles form a nanoscopic mixture with the P3HT. Our pyridine-capped SnS2 nanoparticles are good candidates for fabricating hybrid materials, employing P3HT as the organic compound for application in polymeric-inorganic solar cells.</text>
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                <text>&lt;strong&gt;Bethencourt, Loengrid&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Aguiar, Ivana&lt;/strong&gt;</text>
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                <text>Polymer v. 296, 2024. -- e126832</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>A fraction of rice bran (RB), generated during the brown rice polishing, is utilized to extract oil, resulting in defatted RB (DRB). The aim of this study was to optimize the emulsification conditions to enhance the value of this byproduct by formulating potential vegan dressings and characterizing them. Enzymatic hydrolysis of the starch present in DRB yields the DRB concentrate (DRBC). A central composite design was applied and the results were analyzed using response surface methodology to select optimal conditions for an oil-in-water emulsion formula. Two formulations were chosen: one corresponds to the optimal conditions, with 26.5% of oil and 73.5% of DRBC dispersion (eoptimal), and the other one with 21.7% of oil and 78.3% of dispersion (eED8). The eoptimal formulation exhibited significantly lowermean De Brouckere diameter (D4,3) value and higher viscosity when compared with eED8. For both emulsions, the particle size distribution and D4,3 remained unchanged during storage, whereas viscosity decreased, and backscattering (BS) increased. Initially, both emulsions exhibited solid viscoelastic behavior, whichwas partially lost during quiescent storage. The increase in BS was attributed to particle disaggregation, ultimately leading to the aforementioned change in rheological behavior. In conclusion, although the designed emulsions underwent microstructural changes, they were stable against gravitational separation. To improve stability during quiescent storage, it is suggested to incorporate a thickening agent. Hence, it is propose to procced with the development of a vegan dressing based on the eoptimal emulsion, as it exhibits superior physicochemical properties.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Coping strategies of food insecure households with children and adolescents in Uruguay, a high-income Latin American country: a qualitative study through the lens of Bourdieu&amp;rsquo;s theories of capitals and practice&lt;/strong&gt;</text>
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                <text>Food insecurity has been associated with negative short, medium, and long-term health consequences, which are more detrimental for children and adolescents. These effects may depend on the coping strategies developed to deal with food shortages. The present research aimed at exploring coping strategies in food insecure households with children and adolescents in Uruguay, incorporating sociological theoretical insights from Bourdieu. A qualitative approach based on individual semi-structured interviews was used. A total of 40 interviews were conducted with adults who had parental responsibilities of children and adolescents and who received different types of food assistance, between July and December 2022, in four cities. Results showed that adults tend to develop a wide range of coping strategies aimed at: reducing food expenditure, increasing the availability of money for purchasing food, increasing food availability and/or rationing the food available in the household. Some of the strategies were implemented regardless of the severity of food insecurity, whereas others were characteristic of the moderate and severe levels of the construct. Evidence to support the mediation effect of coping strategies on health outcomes was found. Discourses suggested that lower accumulation of economic and cultural capital may be aligned with the adoption of less socially accepted mechanisms to access to food. Expressions of a specific habitus aimed at securing food were identified among participants with more deprivations. Taken together, the findings suggest that coping strategies may not be a universal or invariant sequence according to the severity of food insecurity and stress the importance of considering households&amp;rsquo; resources and local context for the development of strategies to improve access to food.</text>
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                <text>&lt;strong&gt;Brunet, Ger&amp;oacute;nimo&lt;/strong&gt;</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;p&gt;&lt;strong&gt;Unexpected high yield of acrolein underlies the importance of the&lt;/strong&gt;&lt;br /&gt;&lt;strong&gt;hydrogen-abstraction mechanism in photooxidation of allyl methyl&lt;/strong&gt;&lt;br /&gt;&lt;strong&gt;sulfide (AMS).&lt;/strong&gt;&lt;/p&gt;</text>
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                <text>This work explores theoretically the gas phase oxidation of allyl methyl sulfide (AMS, H2C&amp;ndash;&amp;ndash; CHCH2SCH3) initiated by &amp;bull;OH radicals, focusing on the H-abstraction pathway at the M06-2X-D3/aug-cc-pVTZ and MN15/ aug-cc-pVTZ levels of theory (m06Tz and mn15Tz). The formation of a prereactive complex (PRC) is involved in H-abstraction processes with two potential directions of approach for the OH radical, denoted as &amp;ldquo;&amp;alpha;&amp;rdquo; and &amp;ldquo;&amp;beta;&amp;rdquo;. The PRCs, demonstrate increased reactivity, primarily due to the interaction between the sulfur atoms and the hydroxyl hydrogen. A scheme for the H-abstraction mechanism that supports the experimentally identified products and predicts the formation of some S-containing low volatility products is proposed. The comparison of the potential energy surface (PES) between the double bond addition and H-abstraction paths in the AMS molecule shows that at the m06Tz level of theory, the H-abstraction on C3 and the addition to C1 have nearly the same profile of energy, while at the mn15Tz level, the minimum energy channel is the addition to C1. The theoretical rate coefficient for each reaction channel was calculated, considering the formation of a PRC prior to reaching the transition state of each channel and assuming thermal equilibrium between reactants and the PRC. The rate constants were calculated in a multi-TS/multi-conformer way at the SVECV-f12/m06Tz and SVECVf12/ mn15Tz levels of theory. The SVECV-f12 method is consistent in its predictions in both systems and exhibits only minor deviations from the experimental rate constants. Despite some specific differences due to the DFT method supporting the SVECV-f12 calculations, both methodologies predict a significant H-abstraction contribution in the AMS + OH gas phase reaction, which explains the high formation yield for acrolein determined experimentally.</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Noribogaine (noribo) is the primary metabolite from ibogaine, an atypical psychedelic alkaloid isolated from the root bark of the African shrub Tabernanthe iboga. The main objective of this study was to test the hypothesis that molecular, electrophysiological, and behavioral responses of noribo are mediated by the 5-HT2A receptor (5-HT2AR) in mice. In that regard, we used male and female, 5-HT2AR knockout (KO) and wild type (WT) mice injected with a single noribo dose (10 or 40 mg/kg; i.p.). After 30 min., locomotor activity was recorded followed by mRNA measurements by qPCR (immediate early genes; IEG, glutamate receptors, and 5-HT2AR levels) and electrophysiology recordings of layer V pyramidal neurons from the medial prefrontal cortex. Noribo 40 decreased locomotion in male, but not female WT. Sex and genotype differences were observed for IEG and glutamate receptor expression. Expression of 5-HT2AR mRNA increased in the mPFC of WT mice following Noribo 10 (males) or Noribo 40 (females). Patch-clamp recordings showed that Noribo 40 reduced the NMDA-mediated postsynaptic current density in mPFC pyramidal neurons only in male WT mice, but no effects were found for either KO males or females. Our results highlight that noribo produces sexually dimorphic effects while the genetic removal of 5HT2AR blunted noribo-mediated responses to NMDA synaptic transmission.</text>
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                <text>International Journal of Molecular Sciences, v.25. n&amp;deg;2, 2024. --</text>
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                <text>&lt;strong&gt;&amp;lsquo;It's not something I really think about&amp;rsquo;: Parents' perspectives and practices about how much food to offer in early childhood&lt;/strong&gt;</text>
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                <text>Children are born with an innate capacity to self-regulate their energy intake, but cues from the food environment can undermine children's self-regulation, promoting overconsumption, and challenging energy balance. The size of the portion offered by parents and caregivers has been shown to be correlated with how much food children consume, which is known as the portion size effect. Furthermore, some parental feeding practices may interfere with children's ability to self-regulate. The present research explored parents' perspectives and practices about how much food they offer to their children in Uruguay. Forty-two in-depth interviews with parents of children between 6 months and 5 years old were conducted. Results showed that parental decisions about portion sizes for their children were mostly unconscious and intuitive. Parents were unconcerned about portion sizes, mainly due to the belief that children are able to self-regulate. Although parents identified themselves as mainly responsible for deciding how much food to serve their children, the majority reported to be responsive when their child refuses to eat or finish their meal, or when they request to eat more. Coercive feeding practices were only mentioned by a minority of parents.</text>
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                <text>&lt;strong&gt;Vidal, Leticia&lt;/strong&gt;</text>
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                <text>Journal of Sensory Studies, v.39, 2024. -- e12917.</text>
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                <text>Wiley</text>
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&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
&lt;/div&gt;</text>
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              <description>An account of the resource</description>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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            <name>Title</name>
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                <text>&lt;strong&gt;Influence of the emulsion type on phenytoin bioavailability&amp;nbsp;&lt;/strong&gt;</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>1994</text>
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                <text>To study the influence of the emulsion sign in phenytoin bioavailability two emulsions (w/o and o/w) were prepared. Bioavailability studies were carried out with both emulsions in Wistar male rats. The study was of a randomized two-way cross over design. A radiotracer technique was chosen as analytical procedure due to the small blood sample collected. 14C-phenytoin was synthesized with a high yield and suitable radiochemical purity. It is concluded from a biopharmaceutic point of view that the emulsion sign does not seem to affect the amount of phenytoin absorbed as it is shown through the comparison of the areas under curve up to 24 h. An emulsion with oil as an external phase is responsible of a longer absorption taking into account the apparent elimination constant rates.</text>
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            <name>Creator</name>
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                <text>&lt;strong&gt;Savio, E.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Fagiolino, Pietro&lt;/strong&gt;</text>
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                <text>Bollettino Chimico Farmaceutico v. 133, no. 4, 1994. -- p. 239-245</text>
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            <name>Publisher</name>
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              <elementText elementTextId="696653">
                <text>Societa editoriale farmaceutica</text>
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            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="696655">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Impact of phenylalanine on Hanseniaspora vineae aroma metabolism during wine fermentation&lt;/strong&gt;</text>
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                <text>CULTURAS MIXTAS</text>
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                <text>2024</text>
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                <text>Hanseniaspora vineae exhibits extraordinary positive oenological characteristics contributing to the aroma and texture of wines, especially by its ability to produce great concentrations of benzenoid and phenylpropanoid compounds compared with conventional Saccharomyces yeasts. Consequently, in practice, sequential inoculation of H. vineae and Saccharomyces cerevisiae allows to improve the aromatic quality of wines. In this work, we evaluated the impact on wine aroma produced by increasing the concentration of phenylalanine, the main amino acid precursor of phenylpropanoids and benzenoids. Fermentations were carried out using a Chardonnay grape juice containing 150 mg N/L yeast assimilable nitrogen. Fermentations were performed adding 60 mg/L of phenylalanine without any supplementary addition to the juice. Musts were inoculated sequentially using three different H. vineae strains isolated from Uruguayan vineyards and, after 96 h, S. cerevisiae was inoculated to complete the process. At the end of the fermentation, wine aromas were analysed by both gas chromatography– mass spectrometry and sensory evaluation through a panel of experts. Aromas derived from aromatic amino acids were differentially produced depending on the treatments. Sensory analysis revealed more floral character and greater aromatic complexity when compared with control fermentations without phenylalanine added. Moreover, fermentations performed in synthetic must with pure H. vineae revealed that even tyrosine can be used in absence of phenylalanine, and phenylalanine is not used by this yeast for the synthesis of tyrosine derivatives.</text>
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                <text>&lt;strong&gt;Valera, María José&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Olivera, Valentina&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pérez, Gabriel&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Boido, Eduardo&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Dellacassa, Eduardo&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Carrau, Francisco&lt;/strong&gt;</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>International Journal of Food Microbiology, v.415, 2024. -- e110631</text>
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                <text>Elsevier</text>
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            <name>Rights</name>
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                <text>&lt;div class="element-text"&gt;
&lt;p&gt;&lt;strong&gt;Información sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;La legislación uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;
&lt;/div&gt;</text>
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                <text>Inglés</text>
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                <text>10.1016/j.ijfoodmicro.2024.110631</text>
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                  <text>Bibliografía Nacional Química</text>
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            <element elementId="41">
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              <description>An account of the resource</description>
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          <name>Original Format</name>
          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>PDF</text>
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          <element elementId="50">
            <name>Title</name>
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                <text>&lt;strong&gt;Colesterol total y fracciones en mujeres embarazadas normales&lt;/strong&gt;</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>DIABETES GESTACIONAL</text>
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              <elementText elementTextId="696816">
                <text>RESISTENCIA INSULINICA</text>
              </elementText>
              <elementText elementTextId="696817">
                <text>EMBARAZO</text>
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              <elementText elementTextId="696818">
                <text>COLESTEROL</text>
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                <text>INDICE DE CASTELLI</text>
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              <elementText elementTextId="696820">
                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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              <elementText elementTextId="696821">
                <text>1995</text>
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          <element elementId="87">
            <name>Abstract</name>
            <description>A summary of the resource.</description>
            <elementTextContainer>
              <elementText elementTextId="696822">
                <text>&lt;p&gt;Se reportan laws variaciones del colesterol total y del HDL y no HDL colesterol, as&amp;iacute; como el &amp;Iacute;ndice de Castelli, en un estudio transversal realizado en intervalos de tiempo similares en mujeres embarazadas normales. Los datos provenientes de 210 mujeres embarazadas normales en diferentes estadios, se compararon con los de una poblaci&amp;oacute;n de referencia de 30 mujeres normales no gr&amp;aacute;vidas con edades similares. El colesterol HDL fue aislado con &amp;aacute;cido fosfot&amp;uacute;ngstico/cloruro de magnesio, el colesterol se determin&amp;oacute; enzim&amp;aacute;ticamente y el &amp;Iacute;ndice de Castelli as&amp;iacute; como el no HDL colesterol fueron calculados en cada caso. Nuestro objetivo es estudiar los cambios lip&amp;iacute;dicos en esta poblaci&amp;oacute;n de embarazadas con el prop&amp;oacute;sito de establecer los valores de referencia e investigar si la gestaci&amp;oacute;n podr&amp;iacute;a estar relacionada a situaciones de riesgo cardiovascular. El HDL colesterol decreci&amp;oacute; significativamente entre las semanas 24a y 28a, al tiempo que el &amp;Iacute;ndice de Castelli alcanz&amp;oacute; el m&amp;aacute;ximo valor de riesgo. Desde este punto de vista se puede deducir que este proceso puede estar relacionado con el comienzo de la resistencia a la insulina y el mayor riesgo de aparici&amp;oacute;n de diabetes gestacional.&lt;/p&gt;</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="696823">
                <text>&lt;strong&gt;Raymondo, S.&lt;/strong&gt;</text>
              </elementText>
              <elementText elementTextId="696824">
                <text>&lt;strong&gt;Demiczlo, V.&lt;/strong&gt;</text>
              </elementText>
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                <text>&lt;strong&gt;Pintos, C.&lt;/strong&gt;</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="696826">
                <text>Acta Bioqu&amp;iacute;mica Cl&amp;iacute;nica Latinoamericana v. 29, no. 1, 1995. -- p. 85-91</text>
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          <element elementId="45">
            <name>Publisher</name>
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              <elementText elementTextId="696827">
                <text>Federaci&amp;oacute;n Bioqu&amp;iacute;mica de la Provincia de Buenos Aires</text>
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                <text>1995</text>
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          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="696829">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>A study of 99mTc-adenosine-5'-diphosphate (99mTc-ADP) as a radiopharmaceutical for tumour diagnosis is presented. Two different labelling methods, using SnCl2 in alkaline solution and Zn as reducing agents, were developed. Reduction with Sn(II) alkaline solution was the selected method because a lower concentration of ADP (0.5 mg/mL) could be used and a higher radiochemical yield was achieved. A labelled molecule with a radiochemical purity higher than 95%, in vitro stability of at least 6 hours and an over all negative charge was obtained Biodistribution studies carried out in normal mice and rats revealed rapid urinary excretion and no specific accumulation of activity in any other particular organ. This behaviour was similar to that reported for 99mTc-adenosine-5'-triphosphate (99mTc-ATP). Rapid blood clearance, that could be fitted to a bicompartimental model, was also verified. No evidence of in vivo instability was observed. Studies in mice and rats bearing spontaneous mammary adenocarcinomas were performed and the results were compared to those from the 99mTc-ATP studies. Although the tumour models used were not the same, the incorporation of both labelled compounds was very similar. Radioactivity uptake in the tumour and the tumour-to-blood ratio were not notably high. However, a significant increment was observed in the tumour-to-muscle ratio (1.0 +/- 0.2 at 30 minutes to 2.7 +/- 0.4 at 240 minutes). Whole-body autoradiography enabled tumour visualization. Further investigations, including scintigraphic imaging, must be carried to complete the clinical evaluation of 99mTc-ADP as a tumour seeking agent.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>This research focuses on the identification and quantification of lithium-ion battery degradation indicators at low temperatures. We studied the cycling aging of 18,650 commercial NMC lithium-ion batteries at 10 ◦C. For this purpose, we carried out life cycle tests and performed Galvanostatic Intermittent Titration Technique (GITT) tests in the voltage range for the charge and discharge processes for different States of Health (SoH). The diffusion time constant and the ohmic overpotential were determined from GITT for different SoH. As the batteries degrade both parameters increase. A degradation mechanism associated with faradaic effects (increase in ohmic drop overpotential) and a thermodynamic effect associated with changes in the active material (diffusional time constant) is observed. Furthermore, we performed Electrochemical Voltage Spectroscopy studies through Incremental Capacity (IC) curves. IC curves peaks and valleys are associated with battery phase transformations due to aging phenomena. Each peak has a unique peak height, area, and position associated with a degradation mode. This research focuses on the IC curves derived from the discharge capacities at 3A and OCP (Open Circuit Potential) to study the thermodynamic and faradaic effects separately. The peak at 3.6 V and 3.4 V for the 3A and OCP studies, respectively, is the main feature for the detection of the degradation mechanism. The valley in the OCP curves intensifies with the decrease in SoH and is shifted to lower potentials, an effect that is not observed in the 3A curves. So, we could associate this with thermodynamic effects, Loss of Lithium Inventory (LLI) and Loss of Active Material (LAM) of both the positive electrode and the negative electrode.</text>
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                <text>Two motile, rod-shaped, Gram-stain-negative bacterial strains, TNT11T and TNT19T, were isolated from soil samples collected at Deception Island, Antarctica. According to the 16S rRNA gene sequence similarity, both strains belong to the genus Pseudomonas. Further genomic analyses based on ANI and dDDH suggested that these strains were new species. Growth of strain TNT11T is observed at 0&amp;ndash;30 ℃ (optimum, 20 ℃), pH 4.0&amp;ndash;9.0 (optimum, pH 6.0) and in the presence of 0&amp;ndash;5.0% NaCl (optimum, 1% NaCl), while for TNT19T is observed at 0&amp;ndash;30 ℃ (optimum between 15 and 20 ℃), pH 5.0&amp;ndash;9.0 (optimum, pH 6.0) and in the presence of 0&amp;ndash;5.0% NaCl (optimum between 0 and 1% NaCl). The fatty acid profile consists of the major compounds; C16: 0 and C16: 1 &amp;omega;6 for TNT11T, and C16: 0 and C12: 0 for TNT19T. Based on the draft genome sequences, the DNA G + C content for TNT11T is 60.43 mol% and 58.60 mol% for TNT19T. Based on this polyphasic study, TNT11T and TNT19T represent two novel species of the genus Pseudomonas, for which the proposed names are Pseudomonas violetae sp. nov. and Pseudomonas emilianonis sp. nov., respectively. The type strains are Pseudomonas violetae TNT11T (= RGM 3443T = LMG 32959T) and Pseudomonas emilianonis TNT19T (= RGM 3442T = LMG 32960T). Strains TNT11T and TNT19T were deposited to CChRGM and BCCM/LMG with entry numbers RGM 3443/LMG 32959 and RGM 3442/LMG 32960, respectively.</text>
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                <text>Archives of Microbiology v. 206, 2024</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Ibogaine is a potent atypical psychedelic that has gained considerable attention due to its antiaddictive and antidepressant properties in preclinical and clinical studies. Previous research from our group showed that ibogaine suppresses sleep and produces an altered wakefulness state, which resembles natural REM sleep. However, after systemic administration, ibogaine is rapidly metabolized to noribogaine, which also shows antiaddictive effects but with a distinct pharmacological profile, making this drug a promising therapeutic candidate. Therefore, we still ignore whether the sleep/wake alterations depend on ibogaine or its principal metabolite noribogaine. To answer this question, we conducted polysomnographic recordings in rats following the administration of pure noribogaine. Our results show that noribogaine promotes wakefulness while reducing slow-wave sleep and blocking REM sleep, similar to our previous results reported for ibogaine administration. Thus, we shed new evidence on the mechanisms by which iboga alkaloids work in the brain.</text>
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                <text>We investigated the oxidation and sulfurization of the graphenylene monolayer. Although this structure is unstable when it is 100 % covered with oxygen, obtaining a stable form of oxidized graphenylene is possible for 50 % of coverage. In this structure, the oxygen atoms are added on alternating sides of the monolayer, adopting an epoxy-like structure. It is stable up to 1635 K and is a minimum on the potential surface energy. It is an insulator with an indirect band gap of 5.3 eV, a value much larger than the band gap of the pristine graphenylene. Its sulfur counterpart is stable up to 1256 K, presenting a smaller indirect band gap of 3.5 eV.</text>
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                <text>Context: Finding catalysts that do not rely on the use of expensive metals is one of the requirements to achieve sustainable production. The reactivity of graphene doped with 3d transition metals was studied. All dopants enhanced the reactivity of graphene and performed better than Stone&amp;ndash;Wales defects and divacancies, but were inferior to monovacancies. For hydrogenation of doped-monovacancies, Sc, Ti, Cr, Co, and Ni induced more prominent reactivity on the carbon atoms. However, the metals were the most reactive center for V, Mn, and Fe-doped graphene. Cu and Zn turned the four neighboring carbon atoms into the preferred sites for hydrogenation. The addition of oxygen to doped graphene with Ti, V, Cr, Mn, Fe, Co, and Ni on a monovacancy revealed a more uniform pattern since the metal, preferred to react with oxygen. However, Sc induced a larger reactivity on the carbon atoms. The affinity of the 3d metal-doped graphene systems towards oxygen was inferior to that observed for single-vacancies. Therefore, vacancy engineering is the most favorable and least expensive method to enhance the reactivity of graphene. Methods: We applied Truhlar&amp;rsquo;s M06-L method accompanied by the 6-31G* basis sets to perform periodic boundary conditions calculations as implemented in Gaussian 09. The ultrafine grid was employed and the unit cells were sampled employing 100 k-points. Results were visualized employing Gaussview 5.0.1.</text>
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                <text>&lt;strong&gt;Processing methods for human amniotic membrane as scaffold for tissue engineering with mesenchymal stromal human cells&lt;/strong&gt;</text>
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                <text>CELULAS MADRE</text>
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                <text>CELULA ESTROMAL</text>
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                <text>2024</text>
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                <text>Tissue engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function. The aims of this work were to compare chemically and physically processed human Amniotic Membranes (hAM) and analyze the cytocompatibility and proliferation rate (PR) of two primary human mesenchymal stromal cell lines, from different sources and donor conditions seeded over these scaffolds. The evaluated hAM processes were: cold shock to obtain a frozen amniotic membrane (FEAM) with remaining dead epithelial cells, denudation of hAM with trypsin for 20/10 min (DEAM20/10) or treatment with sodium dodecyl sulfate to decellularized hAM (DAM). All samples were sterilized with gamma radiation. The selection of the treated hAM to then generate composites was performed by scanning and transmission electron microscopy and characterization by X-ray diffraction, selecting DEAM10 and FEAM as scaffolds for cell seeding. Two sources of primary human stromal cells were used, both developed by our researchers, human Dental Pulp Stem Cells (hDPSC) from living donors and human Mesenchymal Stromal Cells (hMSC) from bone marrow isolated from brain dead donors. This last line of cells conveys a novel source of human cells that, to our knowledge, have not been tested as part of this type of construct. We developed four in vitro constructs without cytotoxicity signs and with different PR depending on the scaffolds and cells. hDPSC and hMSC grew over both FEAM and DEAM10, but DEAM10 allowed higher PR.</text>
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                <text>&lt;strong&gt;Echarte, L.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Grazioli, G.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pereira, L.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Francia, A.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;P&amp;eacute;rez, H.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Kuzuian, W.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Vicentino, W.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pardo, H.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Mombr&amp;uacute;, A.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Maglia, &amp;Aacute;.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Touri&amp;ntilde;o, C.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;&amp;Aacute;lvarez, I.&lt;/strong&gt;</text>
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                <text>Cell and Tissue Banking v. 25, n&amp;deg; 1, 2024. -- pp. 269-283</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Ingl&amp;eacute;s</text>
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                <text>10.1007/s10561-022-10014-8</text>
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