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Saredo.&lt;/a&gt; &lt;br /&gt;&lt;a href="https://riquim.fq.edu.uy/files/original/cf76eb6e97d55c18af3137a82d0d12de.pdf" target="_blank" rel="noreferrer noopener"&gt;7 - Marcha sistemática simultánea de aniones y cationes 3era parte: estudio del grupo lateral y 2do grupo.. Juan F. Saredo y José D. Lema..&lt;/a&gt; &lt;br /&gt;&lt;a href="https://riquim.fq.edu.uy/files/original/4e6a76100afd766b49d219c5dd56b909.pdf" target="_blank" rel="noreferrer noopener"&gt;8 - Marcha sistemática simultánea de aniones y cationes 4ta. Parte: Estudio del 3er grupo. José F. Saredo y varios colaboradores.&lt;/a&gt; &lt;br /&gt;&lt;a href="https://riquim.fq.edu.uy/files/original/b4393f71890e8890beda47efa42b6cd3.pdf" target="_blank" rel="noreferrer noopener"&gt;9 - Marcha sistemática simultánea de aniones y cationes 5ta Parte : Estudio del 4to y 5to grupos. Juan F. Saredo; José D. 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Oehninger&lt;/a&gt; &lt;br /&gt;&lt;a href="https://riquim.fq.edu.uy/files/original/6446557bf0fc42a057e6e75dd4d9e1e1.pdf" target="_blank" rel="noreferrer noopener"&gt;24 – Estudio geoquímico orgánico de los niveles calcareos asociados a las lutitas pirobituminosas en la formación Mangrullo, Uruguay. Nilda Medina; Ruben W. Martres; Juan J. Burastero.&lt;/a&gt; &lt;br /&gt;&lt;a href="https://riquim.fq.edu.uy/files/original/63ea32c096eb9b2a161ee69d19ddd98d.pdf" target="_blank" rel="noreferrer noopener"&gt;25 – Lombardochloa, nuevo género de gramineae. B. Rossengurtt; B. R. Arrillaga de Maffei.&lt;/a&gt; &lt;br /&gt;&lt;a href="https://riquim.fq.edu.uy/files/original/190a6757f560b70827364048325a5a95.pdf" target="_blank" rel="noreferrer noopener"&gt;26 – Caracterización de lípidos en lombardochloa rufa (Presl) Roseng. Et Arr. (gramineae). B. Arrillaga de Maffei; M. Bigo de Grosso.&lt;/a&gt;</text>
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                <text>The present study describes the analgesic activity of extracts and some fractions obtained from Erythrina crista-galli leaves in different in vivo analgesic models, using mice as experimental animals. The results showed that extract E2 was the most active, inhibiting 48% of the abdominal constrictions when evaluated against the writhing test at 10 mg kg�1, intraperitoneal. It also caused dose-dependent inhibition in the same model, with a calculated ID50 value and respective confidence interval of 10 (9&amp;ndash;14)mg kg�1, and was more potent than reference drugs. Administered orally, E2 caused potent antinociceptive action, with a calculated ID50 value of 35 (26&amp;ndash;47) mgkg�1. The fractions F1 and F2 obtained from E2 were evaluated against the writhing test at 10 mg kg�1, causing inhibitions of 41 and 88%, respectively. The most active fraction, F2, presented ID50 calculated value of 3 (2&amp;ndash;4) mg kg�1, being about 7-fold more active than the reference drugs (acetyl salicylic acid and acetaminophen). In the formalin test, F2 inhibited both phases of pain (44%, first phase; 58%, second phase). However, in contrast to the results observed for E2, it was not active against the hot-plate test. The phytochemical results showed that at least four main components are present in F2, which show a positive reaction of terpenes with TLC spray reagents.</text>
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                <text>&lt;strong&gt;Natural Product Research, Part A. : Structure and Synthesis v.21, no. 8, 2007. -- p.759-766&lt;/strong&gt;</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege&lt;/strong&gt; el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Analysis of an immunoadjuvant saponin fraction from Quillaja brasiliensis leaves by electrospray ionization ion trap multiple-stage mass spectrometry&lt;/strong&gt;</text>
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                <text>An immunoadjuvant saponin fraction from Quillaja brasiliensis leaves was investigated by direct infusion and liquid chromatography/electrospray ionization ion trap multiple-stage mass spectrometry in negative ion mode (DI-ESI-IT-MSn and LC-ESI-IT-MSn). The aglycone and the sequence of the oligosaccharide residues at C-3 and C-28 were characterized based on MS2 and MS3 experiments of the [MH]&amp;minus; ions. According to their [MH]&amp;minus; ions, characteristic product ions and retention times, 27 bidesmosidic saponins, bearing four types of triterpenic aglycones, were tentatively identified.</text>
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                <text>&lt;strong&gt;Wallace, Federico&lt;/strong&gt;</text>
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                <text>Phytochemistry Letters |g v. 20, 2017. -- p. 228-233</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Cyclophilins (CyPs) are enzymes involved in protein folding. In Trypanosoma cruzi (T. cruzi), the most abundantly expressed CyP is the isoform TcCyP19. It has been shown that TcCyP19 is inhibited by the immunosuppressive drug cyclosporin A (CsA) and analogs, which also proved to have potent trypanosomicidal activity in vitro. In this work, we continue and expand a previous study on the molecular interactions of CsA, and a set of analogs modeled in complexes with TcCyP19. The modeled complexes were used to evaluate binding free energies by molecular dynamics (MD), applying the Linear Interaction Energy (LIE) method. In addition, putative binding sites were identified by molecular docking. In our analysis, the binding free energy calculations did not correlate with experimental data. The heterogeneity of the non-bonded energies and the variation in the pattern of hydrogen bonds suggest that the systems may not be suitable for the application of the LIE method. Further, the docking calculations identified two other putative binding sites with comparable scoring energies to the active site, a fact that may also explain the lack of correlation found. Kinetic experiments are needed to confirm or reject the multiple binding sites hypothesis. In the meantime, MD simulations at the alternative sites, employing other methods to compute binding free energies, might be successful at finding good correlations with the experimental data.</text>
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                <text>&lt;p align="LEFT"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p style="margin-bottom: 0cm;"&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>We studied in vitro cytokine production by peripheral blood mononuclear cells (PBMC) from patients with primary and recurrent hydatid disease when cells were incubated with mitogen (PHA) and antigen from hydatid cyst fluid (HCFAg); levels of specific IgE, IgG4 and eosinophil counts were also measured in sera. When specifically stimulated, PBMC from patients produced higher levels of IL-2 (P &amp;lt; 0&amp;middot;02), IFN- g (P &amp;lt; 0&amp;middot;0028) and IL-5 (P &amp;lt; 0&amp;middot;01) than those from uninfected donors, whereas IL-10 levels were comparable. Notably, IL-5 was also produced in higher levels (P &amp;lt; 0&amp;middot;01) by PBMC from patients when incubated with PHA. The IL-5:IFN- g ratio was significantly greater (P &amp;lt; 0&amp;middot;02) when measured in response to specific stimulation than it was for PHA-stimulated cultures. These cytokine data suggest a bias towards a Th2-response which is in agreement with the high levels of IgG4 and IgE observed. The polarized response appears to be related to clinical status, as differences between patients with primary infec- tion and those with relapse of disease were demonstrated, with significantly higher levels of IgE (P &amp;lt; 0&amp;middot;003), IgG4 (P &amp;lt; 0&amp;middot;04) titres and eosinophil counts (P &amp;lt; 0&amp;middot;04) in the latter; in addition a tendency to an increased production of IL-5 buy lower IFN- g was also observed in this group. These results merit further study as they are suggestive of a putative role of Th2-like responses in susceptibility to reinfection by E. granulosus</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Mate (MT) is a popular South American beverage that has been used as a traditional medicine for centuries, spurring recent interest in its nutraceutical properties.MT is prepared as an infusion of leaves fromthe Yerba Mate (llex paraguriensis) tree. MT has been reported to have antioxidant properties in vitro and in vivo, but these have not been fully characterized in terms of effects against specific radicals. Accordingly, we examined the antioxidant effects of an MT infusion against hydroxyl and superoxide radicals in both chemical and cell culture assays. MT infusions were prepared at 3.10 g/L in boiling water and diluted to experimental dilutions from this stock. Electron spin resonance (ESR) experiments indicated that MT scavenged hydroxyl radicals (produced via the Fenton reaction) and superoxide radicals (produced via the xanthine/xanthine oxidase enzymatic reaction) at all concentrations tested (P &amp;lt;0.05). Further controls indicated that superoxide radical scavengingwas not due to xanthine oxidase inhibition. MT scavenged hydroxyl radicals and decreased cellular oxygen consumption in a dose-dependent manner in Cr(VI)-stimulated RAW 264.7 cells, based on ESR and oxygraph measurements (P &amp;lt; 0.05). Similarly, MT also inhibited hydroxyl-radical-induced lipid peroxidation and DNA damage in a dose-dependent manner in RAW 264.7 cells, based on malondialdehyde and Comet assay data (P &amp;lt; 0.05). This study indicates thatMT possesses potent antioxidant effects against hydroxyl and superoxide radicals in both chemical and cell culture systems, as well as DNA-protective properties. These data further clarify the reported antioxidant effects of YerbaMate infusions. Keywords: antioxidants, DNA damage, free radicals, lipid peroxidation, YerbaMate Introduction Mate (pronounced m&amp;uml;a&amp;rsquo;t&amp;macr;a) is a popular beverage in South American countries, including Paraguay, Argentina, southern Brazil, and Uruguay. Mate (MT) is an infusion brewed from dried leaves and stemlets of the Yerba Mate (llex paraguriensis) holly tree that grows in the southern portion of the Paraguay and Parana River basins (Filip and others 2001). The use of MT as a traditional medicine by the native peoples of Paraguay and Brazil predates the arrival of Spanish and Portuguese explorers. MT is used as a traditional medicine to treat conditions ranging from arthritis to digestive disorders (Bixby and others 2005; Bastos and others 2007). More recent studies have reported that MT has antioxidant and antiobesity properties in humans, while DNA-protective and cholesterol-lowering properties have been reported in animal studies. (Heck and de Mejia 2007; Moraes-de-Souza and others 2008; Matsumoto and others 2009). The chemical composition of MT has been studied extensively and includes xanthines, tannins, chlorogenic and neochlorogenic MS 20090563 Submitted 6/18/2009, Accepted 9/20/2009. Authors Leonard and Hogans are with Health Effects Laboratory Div., Natl. Inst. for Occupational Safety and Health, Morgantown, WV, U.S.A. Author Coppes- Petricorena is with Nutrition &amp;amp; Cancer Laboratory, Dept. of Biochemistry, Faculty of Chemistry,Montevideo,Uruguay. Author Peer is withDept. of Basic Pharmaceutical Sciences, West Virginia Univ., Morgantown, WV, U.S.A. Author Vining is with Auroratrek, Billerica, MA, U.S.A. Author Fleming is with Davenport Univ., Livonia, MI, U.S.A. Author Harris is with Dept. of Food Science, North Carolina State Univ., Raleigh, NC, U.S.A. Direct inquiries to author Leonard (E-mail: SEL5@CDC.GOV). The findings</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Yerba mate infusions are highly consumed and increasingly popular in the world. The evaluation of their chemi cal profiles representing the actual dietary intake may present analytical and interpretation challenges due to the diversity of available products, their drinking procedures, and transfer rates of the compounds into the infusions. There is a general interest in assessing the amounts of polyphenols in human diets to evaluate their potential health-promoting benefits. Thus, the objective of this work was to provide a fast and robust method for the analysis of infusions of yerba mate to evaluate teas with different particle sizes, degree of processing and type. A simple extraction using an espresso machine and ultra-high performance liquid chromatography with diode array detection (UHPLC-DAD) was developed and validated for the determination of theobromine, caffeine, caf feoylquinic and dicaffeoylquinic acids in yerba mate infusions. The chemical profiles of twenty-six yerba mate samples reflected their industrial processes. The dietary intake and the ratio of chlorogenic acids to caffeine of yerba mate was evaluated for different products (aged, green, and roasted yerba mate). The new method proved to be a fast, simple, and fit-for-purpose procedure for the aqueous extraction and determination of bioactive compounds in yerba mate products.</text>
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                <text>Applied Food Research v.2, n&amp;deg;2, 2022. -- e100192</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Temporal Check-All-That-Apply (TCATA) Fading is a variant of TCATA where selected terms gradually and automatically become unselected over a predefined period of time and assessors are asked to re-select the terms if they still apply. Gaps in the temporal profile for a TCATA term may arise if assessors do not immediately re-select a fully faded term, making it difficult to ascertain whether a term did apply continuously over a broken interval or if it did not apply for a period of time. In this context, the aim of the present work was to evaluate the influence of using data imputation to fill the gaps on results from TCATA fading. Eight studies were conducted with consumers or trained assessors using different product categories. Gaps were identified in all of the studies, lasting 0.1&amp;ndash;72.2 s and representing 1&amp;ndash;9% of the raw data. Imputation of gaps from an unselected to a selected state occurred in two ways: imputation of 75% of the gaps with the shortest duration, or imputation of all gaps. Compared to the analysis of the raw data, data imputation provided smoother TCATA curves and slightly increased the duration of the significant differences among samples. Furthermore, the results were more coherent from a sensory point of view, as the evolution of the sensory characteristics during the evaluation period fitted expectations. The present work suggests that data imputation should be considered in the analysis of TCATA Fading data, but further research is required to optimise imputation approaches.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Semiempirical AM1, MNDO-PM3, and MNDO/M, as well as ab initio Hartree&amp;ndash;Fock and M&amp;ouml;ller&amp;ndash;Plesset calculations using the 4-31G, 6-31G(d,p), and 6-31 +G(d,p) basis sets have been done on the water-assisted addition of water to formaldehyde. ab initio methods predict a reduction of 30% of the bimolecular &amp;Delta;G0,&amp;Dagger; (from 48 to 33 kcal/mol) when an ancillary water molecule is used as catalyst. AM1 and MNDO-PM3 predict anticatalysis instead; &amp;Delta;G0,&amp;Dagger; for the termolecular addition is larger than the one for the bimolecular reaction. MNDO/M predicts a modest decrease, from 42 to 39 kcal/mol. We conclude that, as predicted by the ab initio calculations, there is a bifunctional catalysis caused by the ancillary water. Two of the semiempirical methods are qualitatively (and all of them quatitatively) in disagreement with this conclusion</text>
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                <text>Journal of Chemical Theory and Computation v. 13, , 1992. -- p. 1037</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt; ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>There is increasing interest in the use of non-Saccharomyces yeasts in winemaking due to their positive attributes. The non-Saccharomyces yeast Hanseniaspora vineae is an apiculate yeast that has been associated with the production of wine with good fermentation capacity and an increase in aromatic properties. However, this yeast represents a concern in mixed culture fermentation because of its nutrient consumption, especially nitrogen, as its mechanisms of regulation and consumption are still unknown. In this study, we analyzed the nitrogen consumption, as well as the nitrogen catabolism repression (NCR) mechanism, in two genome-sequenced H. vineae strains, using synthetic must fermentations. The use of synthetic must with an established nitrogen content allowed us to study the NCR mechanism in H. vineae, following the amino acid and ammonia consumption, and the expression of genes known to be regulated by the NCR mechanism in S. cerevisiae, AGP1, GAP1, MEP2, and PUT2. H. vineae exhibited a similar amino acid consumption and gene expression profile to S. cerevisiae. However, the wine strain of S. cerevisiae QA23 consumed ammonia and valine more quickly and, in contrast, tyrosine and tryptophan more slowly, than the H. vineae strains. Our results showed a similar behavior of nitrogen regulation in H. vineae and S. cerevisiae, indicating the presence of the NCR mechanism in this Hanseniaspora yeast differentiated before the whole genome duplication event of the Saccharomyces complex. Future study will elucidate if the NCR mechanism is the only strategy used by H. vineae to optimize nitrogen consumpti</text>
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              <elementText elementTextId="534814">
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt; de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Objective: To analyse the process for the development and implementation of&amp;nbsp;mandatory nutritional warning labels inUruguay, in order to inform future nutrition&amp;nbsp;policy making and strategic engagement by public health actors.&lt;br /&gt;Design: The study design drew on policy analysis methodology&amp;nbsp; and case study&amp;nbsp;research methodology. Two main sources of information were selected and analysed&amp;nbsp;for the current study: eighteen official documents from the Uruguayan government&lt;br /&gt;and 259 news reports, published between June 2017 and February 2021.&lt;br /&gt;Setting: Uruguay, Latin America.&lt;br /&gt;Results: The Uruguayan Ministry of Public Health led a cross-sectoral working&amp;nbsp;group composed of diverse governmental stakeholders, international organisations&amp;nbsp;and the academia to develop the front-of-package nutrition labelling policy.&lt;br /&gt;A robust evidence-based approach, based on rigorous scientific knowledge generated&amp;nbsp;in the country, was followed. However, changes in the systemic governing&amp;nbsp;coalition as a consequence of a change in government led to a delay in the entry into force and changes in the regulation. The food industry was the main opponent&amp;nbsp;to the warning label regulation and relied on widely reported corporate political&amp;nbsp;activities to influence the policy process: information and messaging, legal action,&amp;nbsp;policy substitution, opposition, fragmentation and destabilisation.&lt;br /&gt;Conclusions: Key insights to inform future policy action in Uruguay and other jurisdictions&amp;nbsp;were derived. Results stressed the importance of an evidence-based&amp;nbsp;approach for policy design and the early engagement with actors from all the political&lt;br /&gt;system.</text>
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                <text>&lt;p dir="ltr"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p dir="ltr"&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derechode autor&lt;/strong&gt;&lt;span&gt;&amp;nbsp;sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/span&gt;&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
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                <text>The aroma profile of five premium red wines has been studied by sensory descriptive analysis, quantitative gas chromatography-olfactometry (GC-O), and chemical quantitative analysis. The most relevant findings have been confirmed by sensory analysis. Forty-five odorants, including the most intense, were identified. At least 37 odorants can be found at concentrations above their odor threshold. A satisfactory agreement between GC-O and quantitative data was obtained in most cases. Isobutyl- 2-methoxypyrazine, (E)-whiskey lactone, and guaiacol were responsible for the veggie, woody, and toasted characters of the wines, respectively. The sweet-caramel notes are related to the presence of at least five compounds with flowery and sweet notes. The phenolic character can be similarly related to the presence of 12 volatile phenols. The berry fruit note of these wines is related to the additive effect of nine fruity esters. Ethanol exerts a strong suppression effect on fruitiness, whereas norisoprenoids and dimethyl sulfide enhance fruity notes.</text>
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                <text>Journal of Agricultural and Food Chemistry v.55, no. 11, 2007. -- p.4501-4510</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>A bibliographic review of the production of the Uruguayan scientifi c community in Analytical Chemistry and related fi elds, during the period 2000 &amp;ndash; 2012 was performed. The search was carried out using the TIMBO portal (www.timbo.org.uy) available in Uruguay as a universal access to online scientifi c literature and international technology patents banks. A total of 38 journals were selected taking into account the publications of the considered period in Analytical Chemistry and from this search a total of 90 publications were obtained. It was found that 51% of the papers published in this period exhibit cooperation with other countries, mainly with Spain and Brazil. This review shows that Uruguayan scientifi c production in Analytical Chemistry has been increasing and also that there are contributions of Uruguayan researchers groups in high impact journals.</text>
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                <text>&lt;p align="LEFT"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
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&lt;p style="margin-bottom: 0cm;"&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="248057">
                <text>PDF</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="248058">
                <text>Ingl&amp;eacute;s</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="248059">
                <text>Art&amp;iacute;culo</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="248060">
                <text>ISSN 2179-3425</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="248061">
                <text>Uruguay</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
    <tagContainer>
      <tag tagId="1537">
        <name>Producción científica</name>
      </tag>
      <tag tagId="347">
        <name>Química analítica</name>
      </tag>
      <tag tagId="15">
        <name>Uruguay</name>
      </tag>
    </tagContainer>
  </item>
</itemContainer>
