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                <text>Volumen I: Se re&amp;uacute;ne la experiencia y el trabajo de diferentes grupos de investigaci&amp;oacute;n de las principales zonas oliv&amp;iacute;colas del mundo y de nuestro pa&amp;iacute;s en las &amp;uacute;ltimas d&amp;eacute;cadas. Se inicia con un cap&amp;iacute;tulo sobre el desarrollo de la olivicultura en Iberoam&amp;eacute;rica, en el que se recoge informaci&amp;oacute;n sobre la llegada del olivo a Am&amp;eacute;rica y se pretende mostrar su importancia en cada uno de los pa&amp;iacute;ses que lo cultivan. Asimismo presenta una apreciaci&amp;oacute;n de sus fortalezas y debilidades, vistas desde fuera, con las ventajas e inconvenientes que ello representa. Este libro pretende adem&amp;aacute;s llenar un hueco importante en la literatura nacional y regional sobe el desarrollo de este cultivo en zonas templadas y h&amp;uacute;medas; incluye la informaci&amp;oacute;n agroclim&amp;aacute;tica como una herramienta m&amp;aacute;s, que contribuya a la toma de decisiones relativas a la producci&amp;oacute;n de olivos de manera econ&amp;oacute;mica, ambiental y socialmente sostenible. Las personas interesadas en conocer los aspectos t&amp;eacute;cnicos del cultivo podr&amp;aacute;n acceder a informaci&amp;oacute;n sobre el comportamiento local de variedades, plantaci&amp;oacute;n, poda, suelos, nutrici&amp;oacute;n, riego, enfermedades, plagas, olivicultura ecol&amp;oacute;gica y fisiolog&amp;iacute;a de fructificaci&amp;oacute;n y producci&amp;oacute;n. Volumen II: Se re&amp;uacute;ne la experiencia y el trabajo de diferentes grupos de investigaci&amp;oacute;n de las principales zonas oliv&amp;iacute;colas del mundo y de nuestro pa&amp;iacute;s en las &amp;uacute;ltimas d&amp;eacute;cadas. Se inicia con un cap&amp;iacute;tulo sobre la historia del olivo y de su aceite, en el que se recoge informaci&amp;oacute;n acerca de su importancia en las civilizaciones antiguas (en particular, en la mitolog&amp;iacute;a griega), su evoluci&amp;oacute;n en los imperios bizantico y romano, en &amp;eacute;pocas como la Edad Media y el Renacimiento, hasta llegar a la Moderna. Tambi&amp;eacute;n aporta datos sobre su presencia en la Biblia, en el islam as&amp;iacute; como en la literatura universal. Este libro pretende adem&amp;aacute;s llenar un hueco importante en la literatura nacional y regional sobre la tecnolog&amp;iacute;a del aceite de oliva virgen: incluye informaci&amp;oacute;n sobre las etapas de su elaboraci&amp;oacute;n, su composici&amp;oacute;n qu&amp;iacute;mica, los controles anal&amp;iacute;ticos exigidos por normativas internacionales. Un cap&amp;iacute;tulo completo se dedica a su calidad sensorial, al entrenamiento de jueces y caracter&amp;iacute;sticas de su cata. Otros cap&amp;iacute;tulos incluyen informaci&amp;oacute;n sobre la refinaci&amp;oacute;n del aceite de oliva y sobre la tecnolog&amp;iacute;a del aceite de orujo de oliva, de modo que el lector pueda adquirir los conocimientos necesarios para diferenciar todos los tipos de aceites provenientes de las aceitunas que existen en los mercados. En este libro tampoco se descuidan los aspectos vinculados con la nutrici&amp;oacute;n y salud humanas y su uso en diferentes cosm&amp;eacute;ticos, lo que le da una relevancia que va m&amp;aacute;s all&amp;aacute; de la qu&amp;iacute;mica y la tecnolog&amp;iacute;a. Las personas interesadas en conocer los aspectos relacionados con sus aplicaciones gastron&amp;oacute;micas encontrar&amp;aacute;n informaci&amp;oacute;n sobre su maridaje con diferentes tipos de alimentos as&amp;iacute; como novedosas recetas culinarias. Por ello, los coordinadores cient&amp;iacute;ficos de este libro lo pensaron como una obra colectiva en la que participan investigadores locales y extranjeros relacionados con el tema de cada cap&amp;iacute;tulo. La informaci&amp;oacute;n incluida puede ser utilidad tanto para el productor como para el industrial, para los t&amp;eacute;cnicos asesores, los estudiantes, el p&amp;uacute;blico interesado en la olivicultura y los usuarios de aceites de oliva.&lt;br /&gt;&lt;br /&gt;</text>
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                <text>Plant-herbivore interactions have been extensively studied in tomato plants and their most common pests. Tomato plant chemical defenses, both constitutive and inducible, play a role in mediating these interactions. Damaged tomato plants alter their volatile profiles, affecting herbivore preferences between undamaged and damaged plants. However, previous studies on tomato volatiles and herbivore preferences have yielded conflicting results, both in the volatile chemistry itself as well as in the attraction/repellent herbivore response. This study revisits the volatile-mediated interactions between tomato plants and two of their main herbivores: the leafminer Tuta absoluta and the whitefly Trialeurodes vaporariorum. Tomato plant volatiles were analyzed before and after damage by each of these herbivores, and the preference for oviposition (T. absoluta) and settling (T. vaporariorum) on undamaged and damaged plants was assessed both after conspecific and heterospecific damage. We found that both insects consistently preferred damaged plants over undamaged plants. The emission of herbivore-induced plant volatiles (HIPVs) increased after T. absoluta damage but decreased after T. vaporariorum damage. While some of our findings are in line with previous reports, T. absoluta preferred to oviposit on plants damaged by conspecifics, which differs from earlier studies. A comparison of HIPVs emitted after damage by T. absoluta and T. vaporariorum revealed differences in up- or down-regulation, as well as significant variations in specific compounds (12 for T. absoluta and 26 for T. vaporariorum damaged-plants). Only two compounds, &amp;beta;-caryophyllene and tetradecane, significantly varied because of damage by either herbivore, in line with the overall variation of the HIPV blend. Differences in HIPVs and herbivore preferences may be attributed to the distinct feeding habits of both herbivores, which activate different defensive pathways in plants. The plant&amp;rsquo;s challenge in simultaneously activating both defensive pathways may explain the preference for heterospecific damaged plants found in this study, which are also in line with our own observations in greenhouses.</text>
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                <text>Journal of Chemical Ecology, v.49, 2023. --</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
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                <text>While Cannabis sativa L. varieties have been traditionally characterized by their major cannabinoid profile, it is now well established that other plant metabolites can also have physiological effects, including minor cannabinoids, terpenes, and flavonoids. Given the multiple applications of cannabis in the medical field, it is therefore critical to characterize it according to its chemical composition (i.e., its metabolome) and not only its botanical traits. With this in mind, the cannabinoid and metabolomic profiles from inflorescences of two C. sativa varieties with either high D9 -tetrahydrocannabinolic acid (THCA) or high cannabidiolic acid (CBDA) contents harvested at different times were studied. According to results from HPLC and NMR-based untargeted metabolomic analyses of organic and aqueous plant material extracts, we show that in addition to expected variations according to cannabinoid profiles, it is possible to distinguish between harvests of the same variety. In particular, it was possible to correlate variations in the metabolome with presence of powdery mildew, leading to the identification of molecular markers associated with this fungal infection in C. sativa.</text>
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                <text>Frontiers in Plant Science, v.14, 2023.</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Distortion of polyhedra is frequently used in the structure&amp;ndash;property analysis of inorganic materials. The commonly used Baur distortion index (BDI) loses efficacy in dealing with equi-length polyhedra. This work provides an online calculator to characterize the polyhedral distortion on the basis of the best fitted idealized polyhedron (BFIP) method. This method can determine any subtle change between distorted and corresponding idealized polyhedra. It works by fitting an idealized oriented polyhedron of user-selected type to a collection of center and vertex coordinates on an orthonormal basis. The input only needs the coordinates of the center and ligand atoms. It can be accessed at http:// bfip.crystalstructure.cn. The function is demonstrated using a distorted MgO6 octahedron. Examples of the application and comparison with the BDI are given, including a tetrahedron, octahedron, eight-vertex triangular dodecahe dron/cube and cuboctahedron.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya protege el derecho&lt;/strong&gt;&amp;nbsp;de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt;&amp;nbsp;La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>&lt;p&gt;Bi2S3 is a promising solid lubricant for demanding applications, such as oil extraction, heavy mining, and aerospace components. However, its tribological behavior has not been studied in depth. Burnished Bi2S3 soft coatings were evaluated utilizing reciprocating sliding tests under different levels of relative humidity level, normal load, and sliding speed and the results were benchmarked against MoS2 coatings. In addition, ab initio calculations using density functional theory modeling were employed for studying the interaction between the sulfides and the steel substrates and the effect of water intercalation at an atomic level. It was found that Bi2S3 coatings present excellent environmental adaptability and substrate protection over a wide range of testing conditions, thanks to their characteristic crystal structure.&lt;/p&gt;</text>
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                <text>&lt;strong&gt;Pilotti, B.&lt;/strong&gt;</text>
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&lt;p dir="ltr"&gt;&lt;span&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/span&gt;&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Bignoniaceae metabolites as semiochemicals&lt;/strong&gt;</text>
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                <text>Members of the family Bignoniaceae are mostly found in tropical and neotropical regions in America, Asia and Africa, although some of them are cultivated in other regions as ornamentals. Species belonging to this family have been extensively studied in regard to their pharmacological properties (as extracts and isolated compounds). The aim of this review is to summarize the reported scientific evidence about the chemical properties as well as that of the extracts and isolated compounds from species of this family, focusing mainly in insect-plant interactions. As it is known, this family is recognized for the presence of iridoids which are markers of oviposition and feeding preference to species which have became specialist feeders. Some herbivore species have also evolved to the point of been able to sequester iridoids and use them as defenses against their predators. However, iridoids also exhibit anti-insect properties, and therefore they may be good lead molecules to develop botanical pesticides. Other secondary metabolites, such as quinones, and whole extracts have also shown potential as anti-insect agents.</text>
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                <text>Molecules v. 15, 2010. -- p. 7090-7105</text>
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                <text>Four novel alkali&amp;minus;manganese(II) trifluoroacetates were synthesized, and their potential as self-fluorinating precursors to layered perovskites A2MnF4 (A = K, Rb, and Cs) was demonstrated. Na2Mn(tfa)4, K4Mn2(tfa)8, Rb4Mn2(tfa)8&amp;middot;0.23H2O, and Cs3Mn2(tfa)7(tfaH) (tfa = CF3COO&amp;minus; and tfaH = CF3COOH) were grown as single crystals, and their crystal structures solved using X-ray diffraction. Chemically pure K4Mn2(tfa)8, Rb4 Mn2(tfa)8&amp;middot;0.23H2O, and Cs3Mn2(tfa)7(tfaH) were also prepared in polycrystalline form as confirmed by thermal analysis and powder X-ray diffraction. Thermolysis of these powders yielded the isostructural series K2MnF4, Rb2MnF4, and Cs2MnF4 at low temperatures (&amp;asymp;200&amp;minus;300 &amp;deg;C). Trifluoromethyl groups belonging to the trifluoroacetato ligands served as the fluorine source, thereby eliminating the need for external fluorinating agents. K2MnF4 and Rb2MnF4 were obtained as single-phase powders, whereas Cs2MnF4 crystallized along with CsMnF3. Access to polycrystalline Cs2MnF4 coupled to Rietveld analysis enabled elucidation of the crystal structure of this ternary fluoride, which had remained elusive. Findings presented in this article expand the synthetic accessibility of polycrystalline A2MnF4 fluorides, for which a scarce number of routes is available in the literature.&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>A bioactive-guided investigation of the hydro-ethanolic extract of aerial parts of Aristeguietia glutinosa Lam. resulted in the isolation of two diterpenoids, (+)-15-hydroxy-labd-7-en-17-al (1) and (+)-13,14,15,16-tetranor-labd-7-en-17,12-olide (2), as the anti-Trypanosoma cruzi active principles. The structures of 1 and 2 were determined by spectroscopic analysis. The hydro-ethanolic extract showed anti-T. cruzi activity (IC50 = 19.6 microg/mL) whereas the isolated compounds 1 and 2 were near to seven- and one and a half-fold (IC50 = 3.0 and 15.6 microg/mL), respectively more active than the original extract. Labdene 1, equipotent as the reference compound (Nifurtimox), displayed low hemolytic activity, low toxicity against murine macrophages, and absence of mutagenicity. These results support the vernacular medicinal use of this plant as an anti-T. cruzi agent.&lt;br /&gt;&lt;br /&gt;</text>
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                <text>In the search for new therapeutic tools against tuberculosis and to further address the therapeutic potential of pyridine-2-thiol 1-oxide (Hmpo) metal complexes, two new octahedral [M(III)(mpo)3] complexes, with M = Ga or Bi, were synthesized and characterized in the solid state and in solution. Attempts to crystallize [Ga(III)(mpo)3] in CH2Cl2 led to single crystals of the reaction product [GaCl(mpo)2], where the gallium(III) ion is in a square basis pyramidal environment, trans-coordinated at the basis to two pyridine-2-thiolato 1-oxide anions acting as bidentate ligands through their oxygen and sulfur atoms. The biological activity of the new [M(III)(mpo)3] complexes together with that of the previously reported Fe(III) analogous compound and the pyridine-2-thiol 1-oxide sodium salt (Na mpo) was evaluated on Mycobacterium tuberculosis. The compounds showed excellent activity, both in the standard strain H37Rv ATCC 27294 (pan-susceptible) and in five clinical isolates that are resistant to the standard first-line anti-tuberculosis drugs isoniazid and rifampicin. These pyridine-2-thiol 1-oxide derivatives are promising compounds for the treatment of resistant tuberculosis.</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Synopsis&lt;br /&gt;Introduction&lt;br /&gt;&lt;br /&gt;The use of bioadhesive hydrogels for skin care presents important advantages such as long residence times on the application site and reduced product administration frequency.&lt;br /&gt;Object&lt;br /&gt;&lt;br /&gt;The aim of the present work was to develop bioadhesive hydrogels for skin application, using caffeine as a model active ingredient.&lt;br /&gt;Methods&lt;br /&gt;&lt;br /&gt;Eight hydrogels were formulated using binary combinations of a primary polymer (carbomer homopolymer type C (Carbopol&amp;reg; 980) or kappa carrageenan potassium salt (Gelcarin&amp;reg; GP-812 NF)) and a secondary polymer (carbomer copolymer type B (Pemulen&amp;trade; TR-1), xanthan gum or guar gum). Hydrogels were characterized by means of physico-chemical (dynamic rheological measurements, spreadability and adhesion measurements) and sensory methods (projective mapping in combination with a check-all-that-apply (CATA) question). Caffeine hydrogels were formulated using two of the most promising formulations regarding adhesion properties and sensory characteristics. In vitro active ingredient release studies were carried out.&lt;br /&gt;Results&lt;br /&gt;&lt;br /&gt;Hydrogel formulations showed a prevalently elastic rheological behaviour. Complex viscosity of carbomer homopolymer type C hydrogels was higher than that of the kappa carrageenan hydrogels. Besides, complex viscosity values were dependent on the secondary polymer present in the formulation. Significant differences among hydrogels were found in detachment force, work of adhesion and spreading diameter results. Association of projective mapping with CATA allowed to determine similarities and dissimilarities among samples. Cluster analysis associated the samples in two groups. Two hydrogels were selected to study the release of caffeine. Both hydrogels presented similar release profiles which were well described by the Higuchi model. Caffeine release was exclusively controlled by a diffusive process.&lt;br /&gt;Conclusion&lt;br /&gt;&lt;br /&gt;Physico-chemical and sensory techniques enabled the identification of bioadhesive hydrogel formulations with positive characteristics for cosmetic applications. Formulations which combined carbomer homopolymer type C with xanthan gum or with carbomer copolymer type B were the most promising for bioadhesive skin products. Caffeine release profiles of selected formulations were not statistically different. Both hydrogels gradually released the active ingredient, reaching approximately 80% within the first 5 h, and their profiles were well described by the Higuchi model. In this context, it could be concluded that the selected hydrogels are suitable bioadhesive hydrogel formulations for cosmetic application on the skin.&lt;br /&gt;&lt;br /&gt;</text>
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                <text>International Journal of Cosmetic Science v. 37, 2015. -- p. 511-518</text>
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                <text>Albendazole (ABZ) is a broad spectrum anthelmintic benzimidazole with very low bioavailability, and its activity is due to its main metabolite, Albendazole sulphoxide (ABZS). This work demonstrates the improvement of bioavailability when the ABZS is directly administered, compared with the ABZ administration, both orally given. This observation may be used as an interesting target in the design of new drugs with antihelmintic activity in systemic diseases, using ABZS as a parent drug.</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.</text>
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