97 25 6757 https://riquim.fq.edu.uy/files/original/d55fb627decac154aabfc36873f0f3cc.pdf 47a04f8f934ca1a865868e503e4e507f https://riquim.fq.edu.uy/files/original/0ee8cfc185c8447f63f39f338bad1bbc.jpg a2f4d45ccb9250a42fc27fc7f2ec282f Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 153 IPTC Array a:4:{s:7:"caption";s:81:"no spine minimum. full size. Editor: Mark Livingston JEM: Diane RTP: Erin Dalton";s:6:"byline";s:15:"wardsdesign.com";s:12:"byline_title";s:6:"jmcmar";s:11:"object_name";s:30:"Journal of Medicinal Chemistry";} IPTC String caption:no spine minimum. full size. Editor: Mark Livingston JEM: Diane RTP: Erin Dalton byline:wardsdesign.com byline_title:jmcmar object_name:Journal of Medicinal Chemistry Width 115 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Optimization of Antitrypanosomatid Agents :&nbsp; dentification of Nonmutagenic Drug Candidates with in Vivo Activity</strong> Subject The topic of the resource TRIPANOSOMIASIS ANTITRIPANOSOMAS BIBLIOGRAFIA NACIONAL QUIMICA 2014 Abstract A summary of the resource. Chagas disease, caused by Trypanosoma cruzi parasite, was described thousands of years ago. Currently, it affects millions of people, mostly in Latin America, and there are not suitable drugs for treating it. As an attempt to find appropriate drugs to deal with this problem, we report here on the design, synthesis, and characterization of 82 new compounds. Trypanosomicidal behavior in vitro showed more than 20 outstanding derivatives with anti-Trypanosoma cruzi activity. Furthermore, we studied the nonspecific toxicity against mammalian cells determining their selectivity and also performed mutagenicity studies. Proof of concept, in vivo studies, was conducted with two of the most promising derivatives (77 and 80). They were identified as candidates because they have (i) very simple and cost-effective syntheses; (ii) activity against different stages and strains of the parasite showing excellent in vivo behavior during the acute phase of Chagas disease; and (iii) neither nonspecific toxicity nor mutagenic activity. Creator An entity primarily responsible for making the resource <strong>Alvarez, Guzman</strong> <strong>Varela, Javier</strong> <strong>Marquez, Pablo</strong> <strong>Gabay, Mart&iacute;n</strong> <strong>Arias Rivas, Carmen Elena</strong> <strong>Cuchilla, Karina</strong> <strong>Echeverria, Gustavo A.</strong> <strong>Piro, Oscar E.</strong> <strong>Chorilli, Marlus</strong> <strong>Leal, Sandra M.</strong> <strong>Escobar, Patricia</strong> <strong>Serna, Elva</strong> <strong>Torres, Susana</strong> <strong>Yaluff, Gloria</strong> <strong>Vera de Bilbao, Ninfa I.</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Cerecetto, Hugo</strong> Source A related resource from which the described resource is derived Journal of Medicinal Chemistry&nbsp; v. 57, no. 10, 2014. -- p. 3984-3999 Publisher An entity responsible for making the resource available American Chemical Society Date A point or period of time associated with an event in the lifecycle of the resource 2014 Rights Information about rights held in and over the resource <p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi: 10.1021/jm500018m Antitripanosomas Tripanosomiasis https://riquim.fq.edu.uy/files/original/6de194dabec4e6eab0bd43f7f25d55a0.pdf 00856400ed20b3ff9ad90ff1d68f3dcc https://riquim.fq.edu.uy/files/original/b9de5ab8423913147ab39796fcc92e10.gif f76ca94bc073edb8c7beeccb3c84468e Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 150 Width 112 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Second generation of alfa-tocopherol analogs-nitric oxide donors : synthesis, physicochemical, and biological characterization </strong> Subject The topic of the resource TOCOFEROL SINTESIS QUIMICA ORGANICA 2007 BIBLIOGRAFIA NACIONAL QUIMICA Abstract A summary of the resource. Synthesis, physicochemical, and biological characterization of a series of a-tocopherol mimetics with NO-releasing capacity are reported. The selected NO-donor moieties were nitrooxy and furoxan. All products were tested for their in vitro NO-releasing capacities, vasodilating properties and mammal cytotoxic activities. The lipophilic–hydrophilic balance of all products was also evaluated. A new hybrid furoxan, phenol derivative 17, possesses adequate profile of the studied properties. Creator An entity primarily responsible for making the resource <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=8abd84ccbe579b144b1677ae3d4f1405"><strong>López, Gloria V</strong></a> <strong>Blanco, Fabiana</strong> <strong>Hernández, Paola</strong> <strong>Ferreira, Ana</strong> <strong>Piro, Oscar E</strong> <strong>Batthyáni, Carlos</strong> <strong>González, Mercedes.</strong> <strong>Rubbo, Homero</strong> <strong>Cerecetto, Hugo</strong> Source A related resource from which the described resource is derived Bioorganic and Medicinal Chemistry v. 15, no. 18, 2007. -- p. 6262-6272 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2007 Rights Information about rights held in and over the resource <p><strong>Información sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislación uruguaya protege el derecho</strong> de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingles Type The nature or genre of the resource Artículo Identifier An unambiguous reference to the resource within a given context DOI:10.1016/j.bmc.2007.06.019 Química orgánica Síntesis Tocoferol https://riquim.fq.edu.uy/files/original/792366536ea24cd48df1dc30fa5d0a76.pdf c9fd68dc2b74824b156151d0b8664119 https://riquim.fq.edu.uy/files/original/2a00222ca8aed9a7563c0cf247c75241.gif 1bf0af653e9f8d14c6437fada5391037 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 200 Width 153 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors : a deeper insight into the mechanism of inhibition.</strong> Subject The topic of the resource ENFERMEDAD DE CHAGAS TRIPANOSOMA CRUZI BIBLIOGRAFIA NACIONAL QUIMICA 2014 Abstract A summary of the resource. CONTEXT: Triosephosphate isomerase (TIM) is a ubiquitous enzyme that has been targeted for the discovery of new small molecular weight compounds used against Trypanosoma cruzi, the causative agent of Chagas disease. We have identified phenazine and 1,2,6-thiadiazine chemotypes as novel inhibitors of TIM from T. cruzi (TcTIM). OBJECTIVE: Study the mechanism of TcTIM inhibition by a phenazine derivative and by a 1,2,6-thiadiazine derivative. METHODS: We performed biochemical and theoretical molecular docking studies to characterize the interaction of the derivatives with wild-type and mutant TcTIM. RESULTS AND CONCLUSION: At low micromolar concentrations, the compounds induce highly selective irreversible inactivation of parasitic TIM. The molecular docking simulations indicate that the phenazine derivative likely interferes with the association of the two monomers of the dimeric enzyme by locating at the dimer interface, while 1,2,6-thiadiazine could act as an inhibitor binding to a region surrounding Cys-118. Creator An entity primarily responsible for making the resource <strong>Alvarez, Guzman</strong> <strong>Mart&iacute;nez, Jennyfer</strong> <strong>Aguirre L&oacute;pez, Beatriz</strong> <strong>Cabrera, Nallely</strong> <strong>P&eacute;rez-D&iacute;az, Leticia</strong> <strong>Tuena de G&oacute;mez-Puyou, Marietta</strong> <strong>G&oacute;mez-Puyou, Armando</strong> <strong>P&eacute;rez Montfort, Ruy</strong> <strong>Garat Bizzozero, Beatriz Maria</strong> <strong>Merlino Mellognio, Alicia Beatriz</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Cerecetto, Hugo</strong> Source A related resource from which the described resource is derived Journal of enzyme inhibition and medicinal chemistry&nbsp; v. 29, no. 2, 2014. -- p. 198-204 Publisher An entity responsible for making the resource available Taylor &amp; Francis Date A point or period of time associated with an event in the lifecycle of the resource 2014 Rights Information about rights held in and over the resource <p align="LEFT"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p style="margin-bottom: 0cm;"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi: 10.3109/14756366.2013.765415 Enfermedad de chagas Trypanosoma cruzi https://riquim.fq.edu.uy/files/original/a7dfdbde8f08d3ea5c45d54c6711d9e8.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/dfadb16213f37a963621bd33c68a127c.bmp 84c4150aaa571f0f96485d38f5bd513f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>New heteroaryl nitrones with spin trap properties: Identification of a 4-furoxanyl derivative with excellent properties to be used in biological systems.</strong> Subject The topic of the resource RESONANCIA DE SPIN ELECTRONICO TRIPANOSOMIASIS COMPUESTOS HETEROCICLICOS CINETICA BIOLOGIA EXPERIMENTOS CON ANIMALES BIBLIOGRAFIA NACIONAL QUIMICA 2010 Abstract A summary of the resource. their free radical-trapping properties. The physicochemical characterization by electron paramagnetic resonance (EPR) demonstrated its capability to trap and stabilize oxygen-, carbon-, sulfur-, and nitrogen- centered free radicals. The 4-furoxanyl nitrone 3 (FxBN), a(Z)-(3-methylfuroxan-4-yl)-N-tert-butylnitrone, showed appropriate solubility in aqueous solution and taking into account that this physicochemical property is very important for biological applications, we studied it deeply in terms of its trapping and kinetic behaviors. For this, kinetic studies of the hydroxyl adduct decay gave rate constants kST of 1.22 � 1010 dm3 mol�1 s�1 and half-live up to 7200 s at physiological pH, without any artifactual signals. The ability of FxBN to directly traps and stabilizes superoxide free radical, with a half-life of 1620 s at physiological pH, was also demonstrated. Besides, FxBN-hydroxyl and -superoxide adducts exhibited distinct and characteristic EPR spectral patterns. Finally, we confirmed the ability of FxBN to act as spin trap in a specific biological system, that is, in the free radical production of experimental anti-trypanosomatid drugs using Trypanosoma cruzi microsomes as biological system. Moreover, previous observations of low FxBN toxicity transform it in a good candidate for in vivo spin trapping Creator An entity primarily responsible for making the resource <strong>Barriga, Germ&aacute;n</strong> <strong>Olea-Azar, Claudio</strong> <strong>Norambuena, Ester</strong> <strong>Castro, Ana</strong> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=01ded1b48a793797e49a8cb9b67aecea"><strong>Porcal, Williams</strong></a> <strong>Gerpe, Alejandra</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Cerecetto, Hugo</strong> Source A related resource from which the described resource is derived Bioorganic and Medicinal Chemistry v. 18, no. 2, 2010. -- p. 795-802 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2010 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi:10.1016/j.bmc.2009.11.053 Cinetica Compuestos heterociclicos Experimentos con animales Resonancia de spin electrónico Tripanosomiasis https://riquim.fq.edu.uy/files/original/f560835b1d95498094a6411f151fed47.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/e5182a36f701b6188debdbbfa200d7ff.bmp 35c15efae8c8a46ce20bdc29e9508688 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Identification of chalcones as in vivo liver monofunctional phase II enzymes inducers.</strong> Subject The topic of the resource ANTINEOPL&Aacute;SICOS CHALCONAS BIBLIOGRAF&Iacute;A NACIONAL QU&Iacute;MICA 2010 Abstract A summary of the resource. the formation of ultimate carcinogens. CPA could act through various molecular mechanisms, for example by interfering with the action of procarcinogen. This could be attained by increasing the phase II enzymes levels of quinone reductase (QR) and glutathione S-transferase (GST). New flavonoids, especially chalcones, have been identified as in vivo monofunctional phase II enzymes inducers. Oral administration of chalcone, 4, and both p-methoxy-substituted chalcones, 6 and 14, increased hepatic QR activity with concomitant decrease in CYP1A1 activity, a member of the most important group of phase I enzymes cytochrome P450. Among them, 4 also increased GST activity. While p-bromo-substituted chalcone 8 was the best inducer of QR it decreased hepatic GST expression and cytochrome P450, being the most effective decreasing cytochrome P450-expression. Thienyl-chalcone 20 being the bioisostere of chalcone 4 did not display the same in vivo profile in the phase I level modification. As chalcone 4 its bioisostere, chalcone 20, displayed low DNA strand breakage and absence of mutagenicity. Also, in our preliminary in vivo tumourigenesis/chemopreventive and acute-toxicity studies, chalcones 4, 6 and 8 showed the best behaviours as CPA justifying additional studies that are ongoing Creator An entity primarily responsible for making the resource <strong>Cabrera, Mauricio</strong> <strong>Lavaggi Destro, Mar&iacute;a Laura</strong> <strong>Croce, Fiorela</strong> <strong>Celano Jorc&iacute;n, Laura</strong> <strong>Thomson, Leonor</strong> <strong>Fern&aacute;ndez, Marcelo</strong> <strong>Pintos, Cristina</strong> <strong>Raymondo, Stella</strong> <strong>Bollati, Mariela</strong> <strong>Monge, Antonio</strong> <strong>L&oacute;pez de Cer&aacute;in, Adela</strong> <strong>Piro, O.E.</strong> <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes</strong> Source A related resource from which the described resource is derived Bioorganic and Medicinal Chemistry v. 18, no. 14, 2010. -- p. 5391-5399 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2010 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi:10.1016/j.bmc.2010.05.033 Antineoplásicos Chalconas https://riquim.fq.edu.uy/files/original/c8331fd36fa8be3cc0a68758ef4dd7b8.pdf 9409af6c7f305fe8a96381be17603e71 https://riquim.fq.edu.uy/files/original/53a01bb37fedd06c818edd62e637c4f6.png 9537e3a83f7f6cbb66be287d1d9f4f21 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Height 140 Width 438 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Synthetic medicinal chemistry in chagas&acute;disease : Compounds at the final stage of "hit-to-lead" phase</strong> Subject The topic of the resource ENFERMEDAD DE CHAGAS TRIPANOSOMA CRUZI BIBLIOGRAF&Iacute;A NACIONAL 2010 Abstract A summary of the resource. Chagas&rsquo; disease, or American trypanosomosiasis, has been the most relevant illness produced by protozoa in Latin America. Synthetic medicinal chemistry efforts have provided an extensive number of chemodiverse hits at the &ldquo;active-to-hit&rdquo; stage. However, only a more limited number of these have been studied in vivo in models of Chagas&rsquo; disease. Herein, we survey some of the cantidates able to surpass the &ldquo;hit-to-lead&rdquo; stage discussing their limitations or merit to enter in clinical trials in the short term. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes</strong> Source A related resource from which the described resource is derived Pharmaceuticals v.3, no. 4, 2010. -- p. 810 - 838 Publisher An entity responsible for making the resource available Mdpi Date A point or period of time associated with an event in the lifecycle of the resource 2010 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi:10.3390/ph3040810 Enfermedad de chagas Trypanosoma cruzi https://riquim.fq.edu.uy/files/original/24613a46debfc7c35466689f54de768d.doc 0f4e6b73dad25df0b61ca80a92a78d89 https://riquim.fq.edu.uy/files/original/6517f33686eb4c61acb8749ed3413c06.gif 844842e78beec65175c44db71eff508b Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 172 Width 133 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Chemotherapy of Chagas&iuml;s disease : status a new developments</strong> Subject The topic of the resource CHAGAS - ENFERMEDAD QUIMIOTERAPIA 2002 BIBLIOGRAF&Iacute;A NACIONAL QU&Iacute;MICA Abstract A summary of the resource. Chagas disease is a major parasitic problem in developing countries in Central and South America. Chemotherapy for such disease is still insufficient and not effective in its chronic part. Many efforts have been made in recent years to know more about possible new biochemical targets to design new selective drugs. This paper reviews old therapeutic approaches -Nifurtimox, Benznidazole and related compounds- and the latest rationally developed drugs that prove to be active against different parasitic forms - See more at: http://www.eurekaselect.com/81290/article#sthash.7gT0TsBL.dpuf Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes</strong> Source A related resource from which the described resource is derived Current Topics in Medicinal Chemistry v. 2, 2002. -- p. 1187-213 Publisher An entity responsible for making the resource available Bentham Science Date A point or period of time associated with an event in the lifecycle of the resource 2002 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /> <br /> (Por favor lea este aviso antes de abrir los documentos u objetos)<br /> <br /> <strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /> <br /> (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /> <br /> <strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context DOI: 10.2174/1568026023393066 Chagas - Enfermedad Quimioterapia https://riquim.fq.edu.uy/files/original/dc4d45d018a38bedddf65f19fdb892f0.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/0cf0326dc5c8842aeb938a759a8e5387.bmp a32e170823d764e1e12f9f2cf925103f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Naftifine-analogues as anti-Trypanosoma cruzi agents.</strong> Subject The topic of the resource TRIPANOSOMIASIS ANTITRIPANOSOMAS BIBLIOGRAFIA NACIONAL QUIMICA 2010 Abstract A summary of the resource. Chagas disease represents a relevant health problem in Central and South America. The first line of treatment is Nifurtimox and Benznidazole which have a great deal of disadvantages that demands the rapid generation of therapeutic alternatives. Based in our research on aza-thiaheterocycles as anti-Trypanosoma cruzi agents we identified pharmacophores that act through oxidative stress. Here, we describe the synthesis and the activity of new containing bioactive-heterocycles analogues of naftifine as potential T. cruzi membrane sterol biosynthesis inhibitors. Benzimidazole 1,3-dioxides (11 and 13) and quinoxaline 1,4-dioxides (22 and 23) displayed excellent parasite/mammal selectivity indexes. Analysis of the free sterols from parasite incubated with the compounds showed that any of them are able to accumulate squalene suggesting that in the anti-T. cruzi mechanism of action is not involved the inhibition of sterol biosynthesis. Some derivatives were also tested as antifungal agents. The results obtained in the present work open potential therapeutic possibilities of new compounds for these infectious diseases. Creator An entity primarily responsible for making the resource <strong>Gerpe, Alejandra</strong> <strong>Boiani Santurio, Luc&iacute;a</strong> <strong>Hern&aacute;ndez, Paola</strong> <strong>Sortino, Maximiliano</strong> <strong>Zacchino, Susana</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Cerecetto, Hugo</strong> Source A related resource from which the described resource is derived European Journal of Medicinal Chemistry v. 45, no. 6, 2010. -- p. 2154 - 2164 Publisher An entity responsible for making the resource available Elsevier Date A point or period of time associated with an event in the lifecycle of the resource 2010 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> <p>&nbsp;</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi:10.1016/j.ejmech.2010.01.052 Antitripanosomas Tripanosomiasis https://riquim.fq.edu.uy/files/original/647b9b955ca014b0859032230fbcf04c.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/5fa25154b67b9759b2a6927eedc3eb2f.jpg 79e86b133057d7d2f2973e56bc4a2f84 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 205 Width 153 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Structural relationships in the solid state of the anti-chagas agent (E)-phenylethenylbenzofuroxan.</strong> Subject The topic of the resource ENFERMEDAD DE CHAGAS ANTICHAGASICOS BIBLIOGRAFIA NACIONAL QUIMICA 2010 Abstract A summary of the resource. The crystal structure and the vibrational spectrum of a potential drug for Chagas&lsquo;s disease treatment, the (E)-isomer of phenylethenylbenzofuroxan 1 (5(6)(E)- [(2-phenylethenyl)]benzo[1,2-c]1,2,5-oxadiazole N-oxide), are reported. In order to provide insights into structural relationships, quantum mechanical calculations were employed starting from crystal structure. These results have given theoretical support to state interesting structural features, such as the effect of some intermolecular contacts on the molecule conformation and the electronic delocalization decreasing through atoms of the benzofuroxan moiety. Furthermore, the MOGUL comparative analysis in the Cambridge Structural Database provided additional evidences on these structural behaviors of compound 1. Intermolecular contacts interfere on the intramolecular geometry, as, for instance, on the phenyl group orientation, which is twisted by 12.32(6)◦ from the ethenylbenzofuroxan plane. The experimental Raman spectrum of compound 1 presents unexpected frequency shift and also anomalous Raman activities. At last, the molecule skeleton deformation and the characteristic vibrational modes were correlated by matching the experimental Raman spectrum to the calculated one. Creator An entity primarily responsible for making the resource <strong>Martins, F. T.</strong> <strong>Ayala, A. P.</strong> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=01ded1b48a793797e49a8cb9b67aecea"><strong>Porcal, Williams</strong></a> <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez Hormaiztegui, Mar&iacute;a Mercedes</strong> <strong>Ellena, J.</strong> Source A related resource from which the described resource is derived Molecular Diversity v. 14, no. 4, 2010. -- p. 643-652 Publisher An entity responsible for making the resource available Springer Date A point or period of time associated with an event in the lifecycle of the resource 2010 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> <p>&nbsp;</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Inglés Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context DOI 10.1007/s11030-009-9202-4 Antichagásicos Enfermedad de chagas https://riquim.fq.edu.uy/files/original/a202fb5065fd59104b2217e0bd717245.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/526a444f5d241bd95eaa5e4c6591f741.gif 67cef732a8de031a9e75cea6ad570118 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 172 Width 133 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>2-Imidazolone derivatives obtained as unexpected products thtroughout imidazole N3-oxide rearrangement.</strong> Subject The topic of the resource QUIMICA ORGANICA IMIDAZOLONA BIBLIOGRAFIA NACIONAL QUIMICA 2005 Abstract A summary of the resource. 3-Alkyl(aryl)-2,3-dihydro-1H-2-imidazolone derivatives as unexpected product of the reaction between ethyl 3-alkyl(aryl)amino-2-oximinobutanoate and methyl orthoformate is described. These imidazolones are generated by an intramolecular attack and a migration of N3-oxide oxygen from the imidazole N3-oxide intermediates. This proposed mechanism is supported by the results of theoretical studies (DFT). Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gerpe, Alejandra</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Piro, Oscar E</strong> <strong>Castellano, Eduardo E</strong> Source A related resource from which the described resource is derived Letters in Organic Chemistry v. 2, no. 6, 2005. -- p. 501-506 Publisher An entity responsible for making the resource available Bentham Date A point or period of time associated with an event in the lifecycle of the resource 2005 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context DOI: 10.2174/1570178054640778 imidazolona Química orgánica https://riquim.fq.edu.uy/files/original/d74014b9da65f176c2a4c5f1ac454c66.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/16449c0bbc57cc78f0a272ef2a4db48a.gif 326cf12f8f21c3d48ba16b865ba1ab74 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 152 Width 115 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Phenazine 5,10-Dioxide derivatives as hypoxic selective cytotoxins.</strong> Subject The topic of the resource CITOTOXINAS BIBLIOGRAFIA NACIONAL QUIMICA 2005 Abstract A summary of the resource. The synthesis and evaluation as hypoxic selective cytotoxins of 2-amino- or 2-hydroxyphenazine 5,10-dioxide derivatives and reduced analogues are reported. In vitro cytotoxicities on V79 cells under hypoxic and aerobic conditions were determined. Some derivatives, such as 7(8)-bromo-2-hydroxyphenazine 5,10-dioxide, showed selective toxicity toward hypoxic cells and along with derivatives 7(8)-bromo-2-aminophenazine 5,10-dioxide and 7(8)-chloro-2-aminophenazine 5,10-dioxide behave as hypoxic trigger cytotoxins. These compounds represent interesting leads for further chemical modifications and biological studies. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Lavaggi Destro, Mar&iacute;a Laura</strong> <strong>Azqueta, Amaia</strong> <strong>Lopez de Cerain, Adela</strong> <strong>Monge, Antonio</strong> Source A related resource from which the described resource is derived Journal of Medicinal Chemistry v. 48, no. 1, 2005. -- p. 21-23 Publisher An entity responsible for making the resource available American Chemical Society Date A point or period of time associated with an event in the lifecycle of the resource 2005 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> <p>&nbsp;</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi: 10.1021/jm0492150 Citotoxinas https://riquim.fq.edu.uy/files/original/83dbb38dd72446f1477cdc8105ab875d.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/322ff46f578b1117519c43064af76bd6.jpg 5ac07fe910eda96b8132844dd1a74fa0 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 123 Width 96 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Pharmacological properties of furoxans and benzofuroxans : recent developments.</strong> Subject The topic of the resource ANTINEOPLASICOS ANTIINFECCIOSOS FUROXAN BENZOFUROXAN VASODILATADORES BIBLIOGRAFIA NACIONAL QUIMICA 2005 Abstract A summary of the resource. The chemistry of furoxans (1, 2, 5-oxadiazole-2-oxides) and benzofuroxans (benzo[1, 2-c]1, 2, 5- oxadiazole-1-oxides) is very well known. These systems are widely used in organic chemistry as intermediate compounds for the synthesis of numerous heterocycles. In the other hand, furoxan and benzofuroxan derivatives were extensively studied as bioactive compounds. They possess remarkable biological activities, such as anti-microbial and anti-parasitic properties, mutagenic, immunosuppressive and anticancer effects, anti-aggregating and vasorelaxant activity, among others. In some cases, molecular mode of action was proposed. Recently, the research and development in the medicinal chemistry of these systems have produced hybrid compounds in which furoxan or benzofuroxan moieties together with a classical drug moieties are present in a single molecule. So, new anti-ulcer drugs, calcium channel modulators and vasodilator derivatives were described and they are currently in study. In this presentation recent developments in the medicinal chemistry of furoxans and benzofuroxans will be reviewed. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=01ded1b48a793797e49a8cb9b67aecea"><strong>Porcal, Williams</strong></a> Source A related resource from which the described resource is derived Mini-Reviews in Medicinal Chemistry v. 5, no. 1, 2005. -- p. 57-71 Publisher An entity responsible for making the resource available Bentham Date A point or period of time associated with an event in the lifecycle of the resource 2005 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> <p>&nbsp;</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi: 1389-5575/05 Antiinfecciosos Antineoplásicos Benzofuroxan Furoxan Vasodilatadores https://riquim.fq.edu.uy/files/original/56a1252aa70d5951cdc46a15ff9cd235.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/c31059c952796e203da241cf87365c7d.jpg 8035427299b1212b113dc2f86051a05c Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 228 Width 171 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>New synthetic approach for the preparation of imidazole N3-oxide.</strong> Subject The topic of the resource SINTESIS ORGANICA IMIDAZOL BIBLIOGRAFIA NACIONAL QUIMICA 2004 Abstract A summary of the resource. A new synthetic procedure of 1-alkyl(aryl)-1H-4-methylimidazole N 3-oxide derivatives by cyclocondensation of &alpha;-amine&shy;oximes and orthoesters was studied. Low yields in the cyclization process were the result of predominant Z-stereoisomer around the oxime moiety of &alpha;-amineoxime reactants. Different attempts to improve these yields were assayed, mild conditions being those that produce the best results. Also, the special acidity of hydrogen-2 in the imidazole N 3-oxide system was studied in solution by NMR spectroscopy. This property provides a convenient intermediate to access 2-substituted analogues. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gerpe, Alejandra</strong> <strong>Gonz&aacute;lez, Mercedes.</strong> <strong>Fern&aacute;ndez Sainz, Yolanda</strong> <strong>Piro, Oscar E</strong> <strong>Castellano, E</strong> Source A related resource from which the described resource is derived Synthesis no. 16, 2004. -- p. 2678-2684 Publisher An entity responsible for making the resource available Thieme Date A point or period of time associated with an event in the lifecycle of the resource 2004 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context DOI: 10.1055/s-2004-831212 Imidazol Síntesis orgánica https://riquim.fq.edu.uy/files/original/9b769651eacd0f01cfcd07e5d3957107.pdf 24c274ba3d511b97d4d00fdd34605394 https://riquim.fq.edu.uy/files/original/746ef588ad243f7642c68bc2f958c2eb.gif 959d5403f949fb47c6fc66415c2648d7 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 201 Width 300 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Mass spectrometry of 1,2,5-oxadiazole N-oxide derivatives. Use of deuterated analogues in fragmentation pattern studies.</strong> Subject The topic of the resource ANTITRIPANOSOMAS QUIMICA ESPECTROSCOPIA BIBLIOGRAFIA NACIONAL QUIMICA 2004 Abstract A summary of the resource. This paper reported on the study of fragmentation pattern in mass spectrometry of 1,2,5-oxadiazole N-oxide derivatives involving deuterium-labeled analogues to identify some critical fragmentations. A neutral CH2O loss from 3-hydroxymethyl-N2-oxide-4-phenyl-1,2,5-oxadiazole was confirmed with the corresponding mono-deuterated analogue. An OH loss, involving the oxygen of N-oxide, via b-H and d-H rearrangement, was clearly revealed from 3-(4-methylpiperazine-1-ylmethyl)-N2 -oxide-4-phenyl-1,2,5-oxadiazole using the adequate tetra-deuterated analogue. N-oxide isomer and deoxygenated analogues were also used to confirm the participation of the oxide moiety in the fragmentation process. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes.</strong> <a title="Curiculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=502f70a0642a910f5abf0e0d5c853b61"><strong>Seoane, Gustavo</strong></a> <strong>Stanko, C</strong> <strong>Piro, Oscar E</strong> <strong>Castellano, Eduardo E</strong> Source A related resource from which the described resource is derived Journal of the Brazilian Chemical Society v. 15, no. 2, 2004. -- p. 232-40 Publisher An entity responsible for making the resource available Sociedade Brasileira de Qu&iacute;mica Date A point or period of time associated with an event in the lifecycle of the resource 2004 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> <p>&nbsp;</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi.org/10.1590/S0103-50532004000200012 Antitripanosomas Espectroscopía Química https://riquim.fq.edu.uy/files/original/9ff455cbc7c26f57537bf1e2cfdfef02.jpg 973ae29648b073330598e152346df890 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 215 Width 153 https://riquim.fq.edu.uy/files/original/6e51d1337cc49fbb8b14dc9a4b664a4e.pdf 53a840b87c1cb26c75320b931b711bdf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>1,2,4 triazine N-oxide and di-N-oxide derivatives. Studies as potential hypoxic cytotoxins and DNA binder</strong> Subject The topic of the resource CITOTOXINAS BIBLIOGRAFIA NACIONAL QUIMICA 2001 Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Onetto, S</strong> <strong>Risso Lavignasse, Mariela</strong> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=f4e5f5966e2f949cc6ad308da8978be6"><strong>S&aacute;enz, Patricia</strong></a> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=502f70a0642a910f5abf0e0d5c853b61"><strong>Seoane, Gustavo</strong></a> <strong>Bruno, A. M</strong> <strong>Alarcon, J</strong> <strong>Olea-Azar, C</strong> <strong>L&oacute;pez de Cerain, A</strong> <strong>Ezpeleta, O</strong> <strong>Monge, A</strong> Source A related resource from which the described resource is derived Medicinal Chemistry Research v. 10, no. 5, 2001. -- p. 328-337 Publisher An entity responsible for making the resource available Springer Date A point or period of time associated with an event in the lifecycle of the resource 2001 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context ISSN: 1054-2523 Citotoxinas https://riquim.fq.edu.uy/files/original/494f7b8fc189990306e9e89368b02af3.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/83e5f4312f2a2d24c4d36f0d2ffca053.gif 9fca20c647df4ff8bb67c9cab2d3a164 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 129 Width 100 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>N-oxides as hypoxia selective cytotoxins.</strong> Subject The topic of the resource CITOTOXINAS BIBLIOGRAFIA NACIONAL QUIMICA 2001 Abstract A summary of the resource. N-Oxide-containing compounds have been developed as prodrugs that are selectively bioactivated in the hypoxic cells in tumors. This selectivity is based on the net reduction of the N-oxide moiety in the absence of oxygen, in a one or two-electron process, by reductive enzymes. A wide range of N-oxides have been studied and some of them are currently in clinical use. This review covers the principal families of compounds under study and in clinical trials. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes</strong> Source A related resource from which the described resource is derived Mini reviews in medicinal chemistry v. 1, 2001. -- p. 219-31 Publisher An entity responsible for making the resource available Bentham Date A point or period of time associated with an event in the lifecycle of the resource 2001 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context DOI: http://dx.doi.org/10.2174/1389557013406891 Citotoxinas https://riquim.fq.edu.uy/files/original/1432360cc22d8eecfb38d1f8f3ce0e05.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/dba2780afcdeee86ca26de9fbaebb0de.jpg 12f52e4ab56d94917a25a04cf6e5aabd Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 151 IPTC Array a:1:{s:11:"object_name";s:7:"Unknown";} IPTC String object_name:Unknown Width 115 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>1,2,5-Oxadiazole N-Oxide derivatives and related compounds as potential antitrypanosomal drugs : structure-activity relationships.</strong> Subject The topic of the resource TRIPANOSOMIASIS OXIDACION ENFERMEDADES INFECCIOSAS ANIONES BIBLIOGRAFIA NACIONAL QUIMICA 1999 Abstract A summary of the resource. The syntheses of a new series of derivatives of 1,2,5-oxadiazole N-oxide, benzo[1,2-c]1,2,5-oxadiazole N-oxide, and quinoxaline di-N-oxide are described. In vitro antitrypanosomal activity of these compounds was tested against epimastigote forms of Trypanosoma cruzi. For the most effective drugs, derivatives IIIe and IIIf, the 50% inhibitory dose (ID50) was determined as well as their cytotoxicity against mammalian fibroblasts. Electrochemical studies and ESR spectroscopy show that the highest activities observed are associated with the facile monoelectronation of the N-oxide moiety. Lipophilic-hydrophilic balance of the compounds could also play an important role in their effectiveness as antichagasic drugs. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Di Maio, Rossanna</strong> <strong>Gonz&aacute;lez, Mercedes</strong> <strong>Risso, Mariela</strong> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=f4e5f5966e2f949cc6ad308da8978be6"><strong>S&aacute;enz, Patricia</strong></a> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=502f70a0642a910f5abf0e0d5c853b61"><strong>Seoane, Gustavo</strong></a> <strong>Denicola Creci, Ana Beatriz</strong> <strong>Peluffo, Gonzalo</strong> <strong>Quijano Herrera, Celia L&iacute;a</strong> <strong>Olea-Azar, Claudio</strong> Source A related resource from which the described resource is derived Journal of Medicinal Chemistry v.42, 1999. -- p. 1941-1950 Publisher An entity responsible for making the resource available ACS Date A point or period of time associated with an event in the lifecycle of the resource 1999 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context DOI: 10.1021/jm9805790 Aniones Enfermedades infecciosas Oxidación Tripanosomiasis https://riquim.fq.edu.uy/files/original/7625e0d8415cc978de2ad9a101b3c482.pdf e178036d9674f251826713e8851bbff2 https://riquim.fq.edu.uy/files/original/9758eb13e6e5aa4a4b85a6d0e5ddbe1f.gif 6bb65baf18f94a85f0bfc5abdc645905 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 150 Width 113 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Syntesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives.</strong> Subject The topic of the resource ANTICHAGASICOS TRYPANOSOMA CRUZI SINTESIS SEMICARBAZONAS BIBLIOGRAFIA NACIONAL QUIMICA 1998 Abstract A summary of the resource. Several novel semicarbazones derivatives were prepared from 5-nitro-2-furaldehyde or 5-nitrothiophene-2-carboxaldehyde, and tested in vitro as potential anti-trypanosomal agents. The compounds were prepared in good to excellent yields in 2&ndash;3 steps from readily available starting materials. Some derivatives were found to be active against Trypanosoma cruzi with an activity similar to that of Nifurtimox. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Di Maio, Rossanna</strong> <strong>Ibaurri, Gerardo</strong> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=502f70a0642a910f5abf0e0d5c853b61"><strong>Seoane, Gustavo</strong></a> <strong>Denicola, Ana</strong> <strong>Peluffo, G</strong> <strong>Quijano, Cecilia</strong> <a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=2e3c62395a54ce79c86b7e4fa4b5c3f9"><strong>Paulino, Margot</strong></a> Source A related resource from which the described resource is derived Il Farmaco v. 53, , 1998. -- p. 89-94 Publisher An entity responsible for making the resource available Elservier Date A point or period of time associated with an event in the lifecycle of the resource 1998 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context doi:10.1016/S0014-827X(97)00011-6 Antichagásicos Semicarbazonas Síntesis Trypanosoma cruzi https://riquim.fq.edu.uy/files/original/2ff8646ee91ce33b6847fdca724cef82.pdf 47a04f8f934ca1a865868e503e4e507f https://riquim.fq.edu.uy/files/original/5d811472877e3c0a9ae24d1a50a836a4.jpg ee4dafbd98102d1c80bd527823421f81 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 150 Width 113 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Formal potentials of new analogues of nifurtimox: relationship to activity</strong> Subject The topic of the resource NIFURTIMOX ELECTROQUIMICA SUSTANCIAS ANALOGAS BIBLIOGRAFIA NACIONAL QUIMICA URUGUAY 1992 Abstract A summary of the resource. Electrochemical studies (Formal Potentials and Coulometry) were performed on several analogues of Nifurtimox, in order to gain insight on the proposed mechanism of action of these drugs. It is thought that Nifurtimox shows part of its trypanocidal activity via an electron transfer process, leading to the production of active oxygen species that kill the parasite. Formal potentials provide relevant data about the feasibility of electron transfer in vivo. All analogues tested contained the nitro group, which is the most easily reducible group in the parent drug Nifurtimox. The formal potentials values determined ranged from -1.86 to -0.46 V. Coulometric runs were carried out to study the one-electron transfer process. A good correlation between formal potentials and biological activity was found. Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Mester, Brenda</strong> <strong>Onetto, Silvia</strong> <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=502f70a0642a910f5abf0e0d5c853b61" target="_blank"><strong>Seoane, Gustavo</strong></a> <strong>Gonz&aacute;lez, M.</strong> <strong>Zinola, Fernando</strong> Source A related resource from which the described resource is derived Il Farmaco v. 47, no. 9, 1992. -- p. 1207-1213 Publisher An entity responsible for making the resource available Societ&agrave; chimica italiana Date A point or period of time associated with an event in the lifecycle of the resource 1992 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /> <br /> (Por favor lea este aviso antes de abrir los documentos u objetos)<br /> <br /> <strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /> <br /> (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /> <br /> <strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context ISSN: 0014-87X Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Uruguay https://riquim.fq.edu.uy/files/original/7643dff483b8fa2ac3caa7d18713bc6d.pdf 0ebebc2e46cd599f97051dd7aefd7031 https://riquim.fq.edu.uy/files/original/1c01ec6fdcd73ea2ef1fbc3428af7c91.jpg a41e94739fea0755a6246b6d46e14bfd Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 208 Width 150 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Sobre la N-metilaci&oacute;n selectiva de &iacute;ndoles potencialmente &uacute;tiles en imagenolog&iacute;a molecular en enfermedad de Alzheimer : Estudios con "C</strong> Subject The topic of the resource ENFERMEDAD DE ALZHEIMER RADIOQUIMICA CICLOTRON BIBLIOGRAFIA NACIONAL QUIMICA 2015 Abstract A summary of the resource. En la b&uacute;squeda de f&aacute;rmacos para la enfermedad de Alzheimer fueron desarrollados una serie de indoles inhibidores de la enzima GSK-3. El radiomarcado de los mismos resulta de gran inter&eacute;s para estudios radiofarmac&eacute;uticos. En este trabajo se presentan los resultados obtenidos al intentar generar an&aacute;logos portadores de 11C. Creator An entity primarily responsible for making the resource <strong>Fern&aacute;ndez, Soledad</strong> <a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=9b0f413dec677697679ef0eb972502e2" target="_blank"><strong>Rey, Ana</strong></a> <strong>Engler, Henry</strong> <strong>Cerecetto, Hugo</strong> Source A related resource from which the described resource is derived Revista de ADEQ v. 3, no. especial, 2015. -- p. 45-51 Publisher An entity responsible for making the resource available Asociaci&oacute;n de Educadores en Qu&iacute;mica Date A point or period of time associated with an event in the lifecycle of the resource 2015 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong> La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context ISSN: 2301-0991 Ciclotron Enfermedad de Alzheimer Radioquímica https://riquim.fq.edu.uy/files/original/138b036f000bcbed863a6e1e8b56ac53.pdf 0ebebc2e46cd599f97051dd7aefd7031 https://riquim.fq.edu.uy/files/original/ad4253186f09bf220cfa8e133803aae7.jpg de453069d275299474816df0a063b93d Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 262 Width 200 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Investigaci&oacute;n y desarrollo de agentes activos frente a Trypanosoma cruzi : Identificaci&oacute;n de potenciales f&aacute;rmacos antichag&aacute;sicos</strong> Subject The topic of the resource TRIPANOSOMIASIS ENFERMEDADES PARASITARIAS ENFERMEDAD DE CHAGAS LIBROS-ANALITICA BIBLIOGRAFIA NACIONAL QUIMICA 2009 Creator An entity primarily responsible for making the resource <strong>Cerecetto, Hugo</strong> <strong>Gonz&aacute;lez, Mercedes</strong> Source A related resource from which the described resource is derived A 100 a&ntilde;os del descubrimiento de la enfermedad de Chagas contribuciones desde Uruguay Organizaci&oacute;n Panamericana de la Salud Montevideo : OPS 2009. -- p. 73-90 Publisher An entity responsible for making the resource available Organizaci&oacute;n Panamericana de la Salud Date A point or period of time associated with an event in the lifecycle of the resource 2009 Rights Information about rights held in and over the resource <p class="western" style="margin-bottom: 0cm; line-height: 100%;"><strong>Informaci&oacute;n sobre Derechos de Autor</strong><br /> <br /> (Por favor lea este aviso antes de abrir los documentos u objetos)<br /> <br /> <strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes<br /> <br /> (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)<br /> <br /> <strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Español Type The nature or genre of the resource Cap&iacute;tulo de Libro Enfermedad de chagas Enfermedades parasitarias Libros-Analítica Tripanosomiasis https://riquim.fq.edu.uy/files/original/9fdcd1c7f2f51e23dac2504fe9c8fe36.pdf 26eae7e0c2a58a43c61fe0694186c6ec https://riquim.fq.edu.uy/files/original/5ebbe90f4c9857d67afa0bf76322cca6.jpg 5ab218b66d8948b730f5a5f206b291c2 Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 146 Width 118 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data Pdf <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>The social representations of complementary feeding</strong> Subject The topic of the resource ALIMENTOS <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> ALIMENTOS COMPLEMENTARIOS <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> INVESTIGACION CUALITATIVA <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> ASOCIACION DE PALABRAS <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> BIBLIOGRAFIA NACIONAL QUIMICA <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> 2021 <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Abstract A summary of the resource. The social representations of complementary feeding are expected to shape parents&rsquo; decisions and to provide justification or legitimization for their practices. The aims of the present work were: i) to explore the social representations of complementary feeding in parents and health professionals, ii) to evaluate if the onset of complementary feeding modify social representations in parents, and iii) to compare the representations of parents and pediatricians. Three groups of participants were considered: 170 parents of children who had not started complementary feeding (1&ndash;4 months old), 170 parents of children who had started complementary feeding (7&ndash;10 months old) and 212 pediatricians. Parents were recruited in health facilities in Montevideo (Uruguay), whereas pediatricians were recruited at the National Pediatrics Conference. Participants were asked to complete a word association task with &ldquo;the first meals of a baby&rdquo;. All the responses provided by participants were grouped into categories using content analysis. The structure of the social representations was assessed considering the frequency of mention and the average rank of appearance of the categories. Results showed that the social representations of complementary feeding for both parents and pediatricians were extremely narrow and mainly focused on specific foods: puree and a small set of vegetables and fruits. None of the categories showed high frequency of mention and low rank of appearance, indicating that the structure of the social representations did not include any element in the first periphery. According to the theory of social representations, results from the present work suggest that the social representations of complementary feeding for Uruguayan parents and pediatricians are deeply rooted and resistant to change. <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Creator An entity primarily responsible for making the resource <strong>Brunet, Ger&oacute;nimo</strong> <strong>Vidal, Leticia</strong> <strong>Bove, Isabel</strong> <strong>Girona, Alejandra</strong> <strong>Iragola, Valentina</strong> <strong>Ceriani, Florencia</strong> <strong>Rodr&iacute;guez, Raquel</strong> <strong>Mart&iacute;nez, Andrea</strong> <strong>Fuletti, Dar&iacute;o</strong> <strong>Gast&oacute;n, Ares</strong> Source A related resource from which the described resource is derived Appetite v. 165, 2021.-- p. 1-9, e105324 <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Publisher An entity responsible for making the resource available Elsevier <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Date A point or period of time associated with an event in the lifecycle of the resource 2021 <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Format The file format, physical medium, or dimensions of the resource Pdf <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Language A language of the resource Ingl&eacute;s <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Type The nature or genre of the resource Art&iacute;culo <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Identifier An unambiguous reference to the resource within a given context https://doi.org/10.1016/j.appet.2021.105324 <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> <div id="sconnect-is-installed" style="display: none;">2.11.0.0</div> Alimentos Alimentos complementarios Asociación de palabras Investigación cualitativa https://riquim.fq.edu.uy/files/original/8e4a60a89ad230d13f887123f51952ed.pdf ebc40d6f34d69d904c84d520837a57e1 https://riquim.fq.edu.uy/files/original/a0794a0cecb8fbd7a0d5919daa51d7a9.jpg 95b623e43a2f57cf362065dd5f921d6d Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 178 Width 137 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Glucose 6-phosphate dehydrogenase deficiency in pleiotropic carbohydrate-negative mutant strains of Rhizobium meliloti</strong> Subject The topic of the resource ENZIMAS RHIZOBIUM MELILOTI CARBOHIDRATOS BIBLIOGRAFIA NACIONAL QUIMICA 1984 Abstract A summary of the resource. Several mutant strains of Rhizobium meliloti isolated after nitrosoguanidine mutagenesis were selected as unable to grow on mannose. Some of them also failed to grow on glucose, fructose, ribose, and xylose but grew on L-arabinose, galactose, and many other carbon sources. Biochemical analysis demonstrated that the mutants lacked NAD- and NADP-linked glucose-6-phosphate dehydrogenase activities that reside on a single enzyme species. One such mutant was found to accumulate glucose-6-phosphate, and this could partially explain the inhibition of growth observed on mixtures of permissive and&nbsp; nonpermissive carbon sources. Symbiotic properties remained unaffected in all these mutants. Creator An entity primarily responsible for making the resource <strong>Cerve&ntilde;ansky, Carlos</strong> <strong>Arias, Alicia</strong> Source A related resource from which the described resource is derived Journal of Bacteriology v. 160, no. 3, 1984. -- p. 1027-1030 Publisher An entity responsible for making the resource available American Society for Microbiology Date A point or period of time associated with an event in the lifecycle of the resource 1984 Rights Information about rights held in and over the resource <p class="western" lang="es-ES" align="left"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p class="western" lang="es-ES">(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p class="western" lang="es-ES"><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p class="western" lang="es-ES">(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p class="western" style="margin-bottom: 0cm;" lang="es-ES"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context <dl class="rprtid"><dt>PMCID:<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC215813/">PMC215813</a></dt></dl> 1984 Bibliografía Nacional Química Carbohidratos Enzimas Rhizobium meliloti https://riquim.fq.edu.uy/files/original/2822fa06937cbdae7d8df09480a7dcbc.pdf 18051a6a3eee618754d8e0a42d6c7ca5 https://riquim.fq.edu.uy/files/original/d142f390aec4c6a00dc1a5fd688a10f6.jpg fe04cc8d5084e845d2b450547f623b5d Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 188 Width 130 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <p><strong>Dosificaci&oacute;n de microcantidades de nitrato y amon&iacute;aco</strong></p> Subject The topic of the resource MICROAN&Aacute;LISIS 1964 BIBLIOGRAF&Iacute;A NACIONAL QU&Iacute;MICA NITRATO AMON&Iacute;ACO Creator An entity primarily responsible for making the resource <strong>Cerve&ntilde;ansky, W. E.</strong> Source A related resource from which the described resource is derived COR : Comunicaciones Originales Cortas y Res&uacute;menes v. 1, no. 5-6, 1964. -- p. 366-369 com. 201 Publisher An entity responsible for making the resource available Asociaci&oacute;n de Estudiantes de Qu&iacute;mica (Uruguay) Date A point or period of time associated with an event in the lifecycle of the resource 1964 Rights Information about rights held in and over the resource <p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p><strong>La legislaci&oacute;n uruguaya protege el derecho de autor</strong> sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource Papel PDF Language A language of the resource Espa&ntilde;ol Type The nature or genre of the resource Art&iacute;culo 1964 Amoniaco Bibliografía Nacional Química Microanálisis Nitrato https://riquim.fq.edu.uy/files/original/7f2dd120de97a485e8175999cde7a9b3.pdf 6936ce8042500562425f6986d13de2a7 https://riquim.fq.edu.uy/files/original/e255d41fa5f1c9d3bc39edbe430c6acf.jpg 95b623e43a2f57cf362065dd5f921d6d Omeka Image File The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files. Bit Depth 8 Channels 3 Height 178 Width 137 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bibliografía Nacional Química Description An account of the resource Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha. Contributor An entity responsible for making contributions to the resource Departamento de Documentación y Biblioteca RIQUIM Document A resource containing textual data. Note that facsimiles or images of texts are still of the genre text. Original Format If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data PDF Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource <strong>Succinate dehydrogenase mutant of Rhizobium meliloti</strong> Subject The topic of the resource BACTERIAS ENZIMAS RHIZOBIUM MELILOTI BIBLIOGRAFIA NACIONAL QUIMICA 1982 Abstract A summary of the resource. A succinate dehydrogenase mutant strain of Rhizobium meliloti was isolated after nitrosoguanidine mutagenesis. It failed to grow on succinate, glutamate, acetate, pyruvate, or arabinose but grew on glucose, sucrose, fructose, and other carbohydrates. The mutant strain showed delayed nodulation of lucerne plants, and the nodules were white and ineffective. A spontaneous revertant strain of normal growth phenotype induced red and effective nodules. Creator An entity primarily responsible for making the resource <strong>Gardiol, A.</strong> <strong>Arias, A.</strong> <strong>Cervenansky, C.</strong> <strong>Mart&iacute;nez-Drets, G.</strong> Source A related resource from which the described resource is derived Journal of Bacteriology v. 151, no. 3, 1982. -- p. 1621-1623 Publisher An entity responsible for making the resource available American Society for Microbiology Date A point or period of time associated with an event in the lifecycle of the resource 1982 Rights Information about rights held in and over the resource <p class="western" lang="es-ES" align="left"><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p> <p class="western" lang="es-ES">(Por favor lea este aviso antes de abrir los documentos u objetos)</p> <p class="western" lang="es-ES"><strong>La legislaci&oacute;n uruguaya</strong> protege el derecho de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes</p> <p class="western" lang="es-ES">(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p> <p class="western" style="margin-bottom: 0cm;" lang="es-ES"><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p> Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource Ingl&eacute;s Type The nature or genre of the resource Art&iacute;culo Identifier An unambiguous reference to the resource within a given context <div class="inline_block four_col va_top show-overflow align_right"> <div class="fm-citation-ids"> <div class="fm-citation-pmcid"><span class="fm-citation-ids-label">PMCID: </span><span>PMC220449</span></div> </div> </div> 1982 Bacterias Bibliografía Nacional Química Enzimas Rhizobium meliloti