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                <text>Previous research has shownthat consumers' sensory and hedonic perceptions could be greatly influenced by the messages highlighted on the front of the packaging, particularly nutrition and health claims for reduced-calorie or functional foods. In food products designed for hunger control, mentioning satiating effects or meal replacement could potentially influence the expected satiety or other perceptions, including those associated with a filling effect. This study investigated the effect of packaging information on consumer perceptions of eleven commercial chocolate-flavoured satiating and meal replacement bars. Projective mapping (Napping&amp;reg;) with a descriptive step was used to profile the expectations elicited by the eleven bars, based on their extrinsic characteristics (without tasting them), with two different groups of consumers in two different scenarios: mapping the samples' packaging and mapping cards with an identical design showing the most important information displayed on the packaging (product name, nutrition information panel and nutrition and health messages or claims). The terms and comments obtained in the two scenarios were analysed and perceptual spaces were generated from the sample location and attributes obtained in the Napping&amp;reg; exercises, using multi factor analysis (MFA). The results showed that when evaluating the real packaging, the consumers mainly focused on the meal replacement- or satiation-related messages and on the images to build up their perception, attaching less or no importance to the nutritional information that was also displayed on the box. When examining the packaging, sensory expectations &amp;ndash; which probably emerged from the images of the bars &amp;ndash; were also a very important factor in placing the samples in the perceptual space.When looking only at the cards, the consumers' grouping and attribute generation focused in great detail on the nutritional information. The calorie content also became a much more important factor in their perceptions of the bars. Interestingly for the product category analysed, messages about &amp;ldquo;satiating&amp;rdquo; and &amp;ldquo;meal replacement&amp;rdquo; effects were clearly distinct and negatively correlated in the consumers' minds.</text>
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                <text>ACEITE DE OLIVA</text>
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                <text>&lt;strong&gt;Raggio, Laura&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Oro&amp;ntilde;o, Mariela&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Feller, Eugene&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Irigaray, B.&lt;/strong&gt;</text>
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                <text>Acta horticulturae v. 1057, 2014. -- p. 643-648</text>
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                <text>ISHS</text>
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                <text>&lt;p align="LEFT"&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p style="margin-bottom: 0cm;"&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>Ingl&amp;eacute;s</text>
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                <text>Art&amp;iacute;culo</text>
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                <text>ISSN : 0567-7572</text>
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        <name>Aceite de Oliva</name>
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        <name>Evaluación sensorial</name>
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      <tag tagId="1056">
        <name>Polifenoles</name>
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          <name>Original Format</name>
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                <text>&lt;strong&gt;Determinaci&amp;oacute;n de la actividad de lipoxigenasa en higados de merluza.&lt;/strong&gt;</text>
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                <text>LIPIDOS</text>
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                <text>HIGADO DE MERLUZA</text>
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                <text>ACEITE DE PESCADO</text>
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                <text>ANALISIS QUIMICO</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2005</text>
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                <text>En el presente trabajo se realizaron estudios para confirmar la existencia de lipoxigenasas activas en los h&amp;iacute;gados de merluza, enzimas que pueden ser las promotoras del deterioro del aceite contenido en los h&amp;iacute;gados. Cuando una soluci&amp;oacute;n conteniendo una mezcla de &amp;aacute;cidos grasos obtenidos a partir del aceite de girasol se incub&amp;oacute; con el agregado de un extracto acuoso obtenido a partir de los h&amp;iacute;gados de merluza, se verific&amp;oacute; un gradual y continuo incremento en la concentraci&amp;oacute;n de hidroper&amp;oacute;xidos en la mezcla. La velocidad de oxidaci&amp;oacute;n de los &amp;aacute;cidos grasos en las incubaciones result&amp;oacute; directamente proporcional a la cantidad de extracto agregado, pudiendo ser eficientemente disminuida por el agregado de antioxidantes. La actividad lipoxigenante encontrada en los h&amp;iacute;gados de merluza es del orden de 100.000 veces menor a la que se determina por el mismo m&amp;eacute;todo para los porotos de soja. El rango &amp;oacute;ptimo de actividad se obtiene en un rango de pH de 8.0 a 8.5.</text>
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                <text>&lt;strong&gt;Margenat, Luc&amp;iacute;a&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=178a48bba0993fb17ba1ac64b40d019c"&gt;&lt;strong&gt;Jachmanian, Ivan&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=6586904caf76687142b8c1917494e201"&gt;&lt;strong&gt;Grompone, Mar&amp;iacute;a Antonia&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Grasas y Aceites v. 56, no. 3, 2005. -- p. 205-208</text>
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            <name>Publisher</name>
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              <elementText elementTextId="281698">
                <text>Instituto de la Grasa</text>
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          </element>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="281699">
                <text>2005</text>
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          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="281700">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora&lt;/p&gt;&#13;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;</text>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
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              <elementText elementTextId="281701">
                <text>PDF</text>
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          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="281702">
                <text>Espa&amp;ntilde;ol</text>
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            <name>Type</name>
            <description>The nature or genre of the resource</description>
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                <text>Art&amp;iacute;culo</text>
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            <name>Identifier</name>
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                <text>ISSN: 1988-4214</text>
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        <name>Aceite de Pescado</name>
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      <tag tagId="167">
        <name>Análisis químico</name>
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        <name>Higado de merluza</name>
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        <name>Lipidos</name>
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              <name>Title</name>
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            <element elementId="41">
              <name>Description</name>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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            <element elementId="37">
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                  <text>Departamento de Documentación y Biblioteca</text>
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                <text>&lt;strong&gt;Correlation range and compressibility of xenon near the critical point&lt;/strong&gt;</text>
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                <text>ESPECTROSCOPIA</text>
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                <text>ESPECTRO DE LA LUZ</text>
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                <text>XENON</text>
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                <text>GASES RAROS</text>
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                <text>1971</text>
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            <name>Creator</name>
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                <text>&lt;strong&gt;Smith, I. W.&lt;/strong&gt;</text>
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora&lt;/p&gt;</text>
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&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>The enzyme penicillin G acylase (PGA) is currently employed at an industrial scale in the hydrolysis of penicillin and cephalosporin G. Here, we describe the preparation of a new immobilized preparation of the enzyme that yields derivatives that are very thermostable and resistant in the presence of organic solvents. The stabilization is obtained via a double strategy. First, using a new epoxy support (Sepabeads), a high degree of multipoint covalent attachment is achieved. A threestep methodology is proposed: (1) immobilization on the support at high ionic strength, (2) promotion of an intense multipoint covalent attachment by incubation for a long time at alkaline pH, and (3) blocking hydrophylization of the support surface. These derivatives are more rigid and therefore more resistant to inactivation by both temperature or organic solvents. Second, the contact of the enzyme with the organic solvent molecules is reduced by generating a highly hydrophilic microenvironment using polymers (polyethylenimine, aldehyde-dextran, and sulfate-dextran). The exact protocol for the production of this environment has been found to be critical to achieve the desired results (final derivatives remain active in 90% of organic solvents). This derivative could be used in the hydrolysis of antibiotics even in media fully saturated with organic solvents, making simpler the current processes of production of 6-aminopenicillanic acid (6-APA) or 7-aminodeacetoxycephalosporanic acid (7-ADCA).</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora&lt;/p&gt;&#13;
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
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                <text>The production, under environmentally benign conditions, of efficient and more cost-effective anti-infective agents (available to the whole mankind) is one of most ambitious dreams of the industrial medicinal chemistry. Semi-synthetic b-lactam antibiotics are very effective anti-infective agents. They are very stable and can be used via oral delivery. They exhibit a very wide spectrum of anti-bacterial activity and minimal side effects after being massively used for a very long time. In this way, we can assume that semi-synthetic b-lactam antibiotics are going to be one of the key anti-infective agents in the next years. The condensation of natural or modified antibiotic nuclei with different acyl donor chains is one of the key steps for the industrial synthesis of these anti-infective agents. Up to now, these condensations are mainly carried out through classical chemical methods and this implies a number of economical, ecological and technological drawbacks (high energy requirements, many protection and deprotection steps, utilization of toxic methylene chloride as solvent, etc). Enzyme biocatalysts may be very useful to catalyse these selective condensations under very mild experimental and environmental conditions. In fact, the possibility of using enzymes to carry out such biotransformations, at laboratory scale, has been discussed and demonstrated a long time ago. However, industrial synthesis of b-lactamic antibiotics is still carried out via unfavorable chemical routes. In fact, enzymes have not been produced in the nature to act in industrial reactors; so they are usually very unstable, inhibited by substrates and products and they may not have ideal catalytic properties for industrial uses (high reaction rates, required selectivity, ability to reach quantitative synthetic yields, stable enough to run a number of reaction cycles, etc). These limitations of enzyme biocatalysis become even more significant mainly when the enzyme is going to be used with non-natural substrates, catalysing non-natural processes and working under non-conventional conditions. However, in the last ten years, a great number of papers have reported substantial improvement of these enzymatic synthetic approaches (new enzymes, better enzyme derivatives, improved reaction designs and so on) and it seems that a massive industrial implementation of enzymes in antibiotic synthesis is approaching. In this review, we would like to make a critical discussion of these very interesting advances in the application of enzyme biocatalysts for the industrial synthesis of semi-synthetic antibiotics.</text>
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                <text>This paper described that glyoxyl activated supports are only able to quantitatively immobilize proteins at alkaline pH values and using highly activated supports (otherwise, immobilization is negligible). Furthermore, the immobilization rate depends on the surface density of glyoxyl groups and not on the total concentration of groups in the suspension. Moreover, the temperature presented a dramatic effect on enzyme immobilization rate and different enzymes become immobilized at very different rates. Finally, it was not possible to detect immobilization of mono aminated compounds at neither alkaline nor neutral pH values. In fact, these supports may be used to purify enzymes due to these great differences in immobilization rate (e.g., glutamate racemase). These special features are not shared with other supports usually utilized for covalent immobilization of enzymes (e.g., glutaraldehyde, cyanogen bromide supports) that are able to immobilize proteins by just one very stable bond and suggesting an unique mechanism for glyoxyl agarose supports. In fact, all these results suggested that each individual amino-glyoxyl bond is very weak. Therefore, the first immobilization of proteins on supports activated with glyoxyl groups, in absence of reducing reagents, needs the simultaneous establishment of, at least, two attachments between the protein and the support. This mechanism promotes that proteins become immobilized by the area/s where the highest lysine residues density is located and explain the high enzyme stabilization usually achieved by using this immobilization technique.</text>
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                <text>Se sintetiz&amp;oacute; y caracteriz&amp;oacute; siete nuevos complejos de vanadio(V) junto a una serie de otros compuestos ya conocidos. Estos compuestos noveles se obtuvieron por modificaci&amp;oacute;n de las t&amp;eacute;cnicas originales. En general, la caracterizaci&amp;oacute;n fisicoqu&amp;iacute;mica y estructural de los compuestos se realiz&amp;oacute; mediante un conjunto de t&amp;eacute;cnicas: an&amp;aacute;lisis elemental, espectroscop&amp;iacute;a electr&amp;oacute;nica UV/Vis y vibracional, difracci&amp;oacute;n de rayos X en polvo microcristalino y monocristal, medida de propiedades magn&amp;eacute;ticas y voltametr&amp;iacute;a c&amp;iacute;clica. En particular, se puso a punto una t&amp;eacute;cnica espectrofotom&amp;eacute;trica de dosificaci&amp;oacute;n de vanadio de uso general, y se realiz&amp;oacute; un estudio vibracional profundo de los compuestos mediante espectroscop&amp;iacute;a IR y Raman, lo que constituye el principal aporte de este Trabajo de Tesis a la Qu&amp;iacute;mica Inorg&amp;aacute;nica B&amp;aacute;sica. Adem&amp;aacute;s, se realiz&amp;oacute; la evaluaci&amp;oacute;n biol&amp;oacute;gica de los compuestos sintetizados en diferentes l&amp;iacute;neas celulares y se estudi&amp;oacute; en detalle los efectos, a nivel celular, de dos compuestos seleccionados. En este Trabajo de Tesis se trabaj&amp;oacute; con tres grupos de compuestos: derivados de vanadio(IV) y vanadio(V) de la tropolona, peroxocompuestos de vanadio(V) y compuestos heterol&amp;eacute;pticos de vanadio(V) hidroxilamido-amino&amp;aacute;cido. Para el caso de los derivados de la tropolona [VIVO(trop)2] y [VVO(trop)2Cl] (trop= ligando tropolonato), se desarroll&amp;oacute; un m&amp;eacute;todo alternativo de s&amp;iacute;ntesis del complejo [VVO(trop)2Cl]; fue analizado su comportamiento electroqu&amp;iacute;mico mediante voltametr&amp;iacute;a c&amp;iacute;clica y las propiedades magn&amp;eacute;ticas del complejo [VIVO(trop)2]. Adem&amp;aacute;s, al igual que para las otras series, se estudi&amp;oacute; en profundidad su espectro vibracional mediante espectroscop&amp;iacute;a IR y Raman. A efectos de facilitar la asignaci&amp;oacute;n de las bandas del espectro vibracional se sintetizaron los complejos [M(trop)2] (donde M = Co, Cu, Zn). Para los complejos de vanadio(V) de ligando peroxo, K3[VO(O2)2CO3]∙H2O y K2[VO(O2)NTA]∙2H2O, se abord&amp;oacute; el estudio de sus propiedades biol&amp;oacute;gicas en las l&amp;iacute;neas celulares osteoblasto-s&amp;iacute;miles MC3T3-E1 (preosteoblasto normal) y UMR196 (c&amp;eacute;lulas derivadas de osteosarcoma de rata). Se evalu&amp;oacute; la capacidad antiproliferativa de los compuestos en ambas l&amp;iacute;neas celulares. Tambi&amp;eacute;n, se estudi&amp;oacute; la acci&amp;oacute;n antiproliferativa del complejo K2[VO(O2)NTA]∙2H2O en c&amp;eacute;lulas derivadas de adenocarcinoma de colon humano (Caco-2) y macr&amp;oacute;fagos de tumor murino RAW264.7. Por ser el ligando hidroxilamido (NH2O) isoelectr&amp;oacute;nico del peroxo, para algunos complejos de f&amp;oacute;rmula general [VO(NH2O)2(aa)]&amp;middot;nH2O (donde aa representa el ligando amino&amp;aacute;cido), ha sido interesante evaluar sus propiedades biol&amp;oacute;gicas en cultivos celulares, utilizando las l&amp;iacute;neas celulares anteriormente mencionadas. En este sentido se ha ensayado inhibici&amp;oacute;n de la fosfatasa alcalina intestinal y proliferaci&amp;oacute;n, alteraciones de morfolog&amp;iacute;a, acci&amp;oacute;n citot&amp;oacute;xica, acci&amp;oacute;n genot&amp;oacute;xica y generaci&amp;oacute;n de estr&amp;eacute;s oxidativo en las l&amp;iacute;neas celulares osteoblasto-s&amp;iacute;miles. Dos de los compuestos fueron evaluados en un modelo in vivo de huevos de pez cebra</text>
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                <text>&lt;strong&gt;Arrambide Brianthe, Gabriel&lt;/strong&gt;</text>
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                <text>Montevideo: UdelaR-Facultad de Qu&amp;iacute;mica</text>
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                <text>2014</text>
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            <description>Information about rights held in and over the resource</description>
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              <elementText elementTextId="282173">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt; La legislaci&amp;oacute;n uruguaya protege el derecho de&lt;/strong&gt; autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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                <text>192 p.</text>
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                <text>Espa&amp;ntilde;ol</text>
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        <name>Vanadio</name>
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            <element elementId="50">
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                  <text>Bibliografía Nacional Química</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="709198">
                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                  <text>Departamento de Documentación y Biblioteca</text>
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                  <text>RIQUIM</text>
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          <description>If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data</description>
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              <text>PDF</text>
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                <text>&lt;strong&gt;Identification of a high molecular weight glyconconjugate from a Uruguayan plant that binds to the tumor associated Tn antigen.&lt;/strong&gt;</text>
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                <text>NEOPLASMAS</text>
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                <text>URUGUAY</text>
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                <text>ANTIGENOS</text>
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                <text>TN-ANTIGENOS</text>
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                <text>BIBLIOGRAFIA NACIONAL QUIMICA</text>
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                <text>2005</text>
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                <text>The Tn determinant (GalNAc-O-Ser=Thr), one of the most specific human carcinoma&amp;ndash;associated structures, can be identified using both monoclonal antibodies and lectins. In this work we have explored, for the first time, the presence of Tn-binding proteins in aqueous extracts of plants collected in Uruguay. A total of 21 extracts from plants belonging to 12 Phanerogam families were screened by an ELISA assay (competitive inhibition of anti-Tn antibody binding) and by hemagglutination (HAG) activity. Five of the extracts displayed binding to Tn residues, although only those extracts prepared from fruit and leaf from Myrsine coriacea (Sw.) R. Br. ex Roem &amp;amp; Schult caused total inhibition of the binding activity of anti-Tn MAb 83D4. Considering that Myrsine coriacea extracts did not display HAG activity against several types of normal red blood cells, we characterized the material with Tn-binding activity from these extracts. We purified this material from Myrsine coriacea leaf extracts using perchloric acid treatment followed by affinity chromatography and reverse-phase high performance liquid chromatography (HPLC), conserving its Tnbinding activity. We found a high-molecular-weight glycoconjugate that has an apparent molecular mass of approximately 670 kDa, as judged by SDS-PAGE.</text>
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                <text>&lt;strong&gt;Medeiros, A&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Pla, A.&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Alonso Paz, Eduardo.&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=8dfa5283acaafc5c73dab5b61b04f9a0"&gt;&lt;strong&gt;Batista-Viera, Francisco.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>&lt;strong&gt;Osinaga, Eduardo.&lt;/strong&gt;</text>
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                <text>&lt;a title="Curriculum" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=729d3d9bb07d7be0ba5e4dc762c01e29"&gt;&lt;strong&gt;Franco, L.&lt;/strong&gt;&lt;/a&gt;</text>
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                <text>Pharmaceutical Biology v. 43, no. 1, 2005. -- p. 26-32</text>
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                <text>Taylor &amp;amp; Francis</text>
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            <name>Date</name>
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                <text>2005</text>
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            <name>Rights</name>
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            <elementTextContainer>
              <elementText elementTextId="286553">
                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
&lt;p&gt;(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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            <description>The file format, physical medium, or dimensions of the resource</description>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>Ingl&amp;eacute;s</text>
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                <text>DOI: 10.1080/13880200590903318</text>
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                <text>Uruguay</text>
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                  <text>Bibliografía Nacional Química</text>
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                  <text>Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.</text>
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                <text>The capacity of yeast to modify anthocyanin concentration during red wine fermentation was studied with the objective of classifying yeast strains according to their capacity for color removal during vinification. A model red grape juice medium was used to better understand yeast-anthocyanin interactions. An anthocyanin extract of Vitis vinifera cv. Tannat was prepared from grape skins and diluted in a white must in order to obtain a red grape juice without solids. Anthocyanin removal was confirmed to be higher for compounds with higher polarity. Acylated anthocyanins (acetyl and p-coumaryl compounds) were differentially removed, and the percentage of removal for each compound was determined. Results showed no correlation between color intensity and total anthocyanin concentration after fermentation, possibly because of the presence of anthocyanin derivatives formed during the process. HPLC-MS analysis allowed identification of anthocyanin derivatives, while the quantification of several derivatives was performed by HPLC-DAD. The sum of these derivatives showed a direct correlation with the color intensity obtained with each strain, thus explaining the color variability observed.</text>
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                <text>&lt;strong&gt;Medina, Karina&lt;/strong&gt;</text>
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                <text>American Journal of Enology and Viticulture v. 56, no. 2, 2005. -- p. 104-109</text>
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                <text>In this paper we report on the magnetic properties of pure bulk ferromagnetic graphite, obtained by a chemical route previously described. This magnetic graphite has been obtained by a vapor reaction consisting of a controlled etching on the graphite structure. By magnetic force microscopy we have verified that its magnetic properties are related to the topographic defects introduced in the pristine material. Also, the magnetic properties have been verified through magnetization measurements as a function of temperature and applied magnetic field. At low temperatures s2 Kd the saturation magnetization reaches a value of 0.58 emu/g, leading to a defect concentration of 1250 ppm. The system is highly irreversible due to the inhomogeneity of the distribution of defects in the material. Two transition temperatures are detected, Tc1=115s5d K and Tc2 =315s5d K. These transitions could be associated to the weak coupling between ferromagnetic regions related to defects and to the ferromagnetism inside the defect regions.</text>
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                <text>&lt;strong&gt;De Lima, O&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Leite, E.&lt;/strong&gt;</text>
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                <text>Physical Review B 71,&amp;nbsp;B: Cond. Matt. Mat. Phys. v. 71, no. 10, 2005. -- p. 100404/1-100404/4</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;</text>
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                <text>DOI: 10.1103/PhysRevB.71.100404</text>
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                <text>As a contribution to the development of novel vanadium complexes with pharmacologically interesting moieties, new dioxovanadium( V) semicarbazone complexes with the formula cis-VO2L, where L = 5-bromosalicylaldehyde semicarbazone and 2-hydroxynaphtalen- 1-carboxaldehyde semicarbazone have been synthesized. and characterized by 1H and 13C NMR, Raman and FTIR spectroscopies. Results were compared with those previously reported for other three analogous complexes of this series. The five complexes were tested in three different human tumor cell lines for bioactivity as potential anti-tumor agents, showing selective cytotoxicity on TK-10 cell line. Results showed that structural modifications on the semicarbazone moiety could have a significant effect on the anti-tumor activity of the vanadium complexes. In addition, the electrochemical behavior of all the complexes was studied. No apparent correlation could be demonstrated between reduction potentials of the complexes and their anti-tumor activities. The molecular structure of the novel [VVO2(5-bromosalicylaldehyde semicarbazone)] complex was solved by X-ray diffraction methods. The vanadium atom shows a distorted square pyramidal coordination sphere. The (VO2)+ cation is coordinated to a nearly planar (L)� anion acting as a tridentate ligand through both oxygen and one nitrogen atoms.</text>
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&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
&lt;p&gt;&lt;strong&gt;La legislaci&amp;oacute;n uruguaya&lt;/strong&gt; protege el derecho de autor sobre toda creaci&amp;oacute;n literaria, cient&amp;iacute;fica o art&amp;iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&amp;oacute;n a lo establecido por el derecho com&amp;uacute;n y las siguientes leyes&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA&lt;/strong&gt; - La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;&#13;
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                <text>&lt;strong&gt;Producci&amp;oacute;n de radiois&amp;oacute;topos y mol&amp;eacute;culas marcadas en el Uruguay&lt;/strong&gt;</text>
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                <text>&lt;strong&gt;Servian, J. L.&lt;/strong&gt;</text>
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                <text>Bolet&amp;iacute;n de la Comisi&amp;oacute;n Nacional de Energ&amp;iacute;a At&amp;oacute;mica (Uruguay) v. 2, 1972. -- p. 21</text>
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                <text>Comisi&amp;oacute;n Nacional de Energ&amp;iacute;a At&amp;oacute;mica (Uruguay)</text>
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                <text>1972</text>
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                <text>&lt;p&gt;&lt;strong&gt;Informaci&amp;oacute;n sobre Derechos de Autor&lt;/strong&gt;&lt;/p&gt;&#13;
&lt;p&gt;(Por favor lea este aviso antes de abrir los documentos u objetos)&lt;/p&gt;&#13;
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&lt;p&gt;&lt;strong&gt;ADVERTENCIA -&lt;/strong&gt; La consulta de este documento queda condicionada a la aceptaci&amp;oacute;n de las siguientes condiciones de uso: Este documento es &amp;uacute;nicamente para usos privados enmarcados en actividades de investigaci&amp;oacute;n y docencia. No se autoriza su reproducci&amp;oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&amp;oacute;n o cita de partes debe indicarse el nombre de la persona autora.&lt;/p&gt;</text>
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            <name>Format</name>
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                <text>In order to assess the utility of mtDNA typing for forensic purposes in Uruguay, a population sample of 120 maternally unrelated individuals were amplified and directly sequenced for the HV1 and for the HV2 segments in the control region of the human mtDNA, following previous international recommendations (1). Blood and saliva samples were taken from 120 unrelated individuals and deposited into FTA cards (FTA card, Whatman WB 12-0205). The DNA was extracted in a 1.2 mm punch according to the manufacturer recommendations. DNA amplification and sequencing was performed according to previously published paper (2). All statistical analysis were calculated using the Arlequin Software ver. 2.000 (3). Results are shown in Table 1. In this population sample, 107 different mtDNA sequences were observed out of 120 individuals. Of these, 97 sequences were observed once (80.8%), 8 sequences were observed twice (13.3%), one sequence was observed three times (2.5%), and another four times (3.3%). The variation of mtDNA HV1 and HV2 regions was confined to 146 positions, of which 99 was observed in the HV1 and 47 in the HV2. Sequence variation consisted of 120 transitions, 21 transversions, and 11 indels. The genetic diversity value for combined HV1 and HV2 regions was 0.998 (&amp;plusmn;0.002) in this Uruguayan population sample, and the nucleotide diversity was 0.068 (&amp;plusmn;0.035). The complete dataset is available to any interested researcher at: http://www.lorgen.com/forense</text>
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                <text>Journal of Forensic Sciences v. 50, no. 5, 2005. -- p. 1239-1242</text>
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              <elementText elementTextId="282624">
                <text>Uruguay</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
    <tagContainer>
      <tag tagId="1449">
        <name>Genética</name>
      </tag>
      <tag tagId="15">
        <name>Uruguay</name>
      </tag>
    </tagContainer>
  </item>
</itemContainer>
