1
25
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https://riquim.fq.edu.uy/files/original/0a0423dd481d2e901798bd37dec61d08.pdf
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https://riquim.fq.edu.uy/files/original/7783050194e036a111071ca515a0e22a.jpeg
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Omeka Image File
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8
Channels
3
Height
155
Width
117
Dublin Core
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Title
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Bibliografía Nacional Química
Description
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Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.
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Departamento de Documentación y Biblioteca
RIQUIM
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PDF
Dublin Core
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Title
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<strong>Immunology of a unique biological structure : the Echinococcus laminated laye</strong>
Subject
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MUCINAS
ECHINOCOCCUS
MACROFAGO
CELULA DENDRITICA
BIBLIOGRAFIA NACIONAL QUIMICA
2023
Abstract
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The larval stages of the cestode parasites belonging to the genus Echinococcus grow within internal organs of humans and a range of animal species. The resulting diseases, collectively termed echinococcoses, include major neglected tropical diseases of humans and livestock. Echinococcus larvae are outwardly protected by the laminated layer (LL), an acellular structure that is unique to this genus. The LL is based on a fibrillar meshwork made up of mucins, which are decorated by galactose-rich O-glycans. In addition, in the spe cies cluster termed E. granulosus sensu lato, the LL features nano-deposits of the calcium salt of myo-inositol hexakisphosphate (Insp6 ). The main purpose of our article is to update the immunobiology of the LL. Major recent advances in this area are (i) the demonstra tion of LL “debris” at the infection site and draining lymph nodes, (ii) the characterization of the decoy activity of calcium Insp6 with respect to complement, (iii) the evidence that the LL mucin carbohydrates interact specifically with a lectin receptor expressed in Kupffer cells (Clec4F), and (iv) the characterization of what appear to be receptor-independent effects of LL particles on dendritic cells and macrophages. Much information is missing on the immunology of this intriguing structure: we discuss gaps in knowledge and propose possible avenues for research.
Creator
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<a href="https://export.cvuy.uy/cv/?c855a45b7dae1af50c961a96b5eb15c26a7b943e53f84d972caa0f9ce21ec5f03ef21e57ce461b5656b60c7a13dbc71dbc1dad52a109e231d5b638ac5639067d" target="_blank"><strong>Díaz, Alvaro</strong></a>
<strong>Barrios, Anabella A.</strong>
<a href="https://export.cvuy.uy/cv/?2ca18030e9df5796c4b407a15ce6bd9131cb2651efe6590bfdf2e8c713c104e026f3235f1dfeca349bb1ecb305bb490c48d0b7ac0cdd6a12e0ab8cb8ea7ea4b6" target="_blank"><strong>Grezzi, Leticia</strong></a>
<strong>Mouhape, Camila</strong>
<strong>Jenkins, Stephen J.</strong>
<strong>Allen, Judith E.</strong>
<a href="https://export.cvuy.uy/cv/?046921b42c1ed550abf30bd7a1f80ffab5fb2cb68c5100d528e93daa2c688f6380e00f810c1886d7b4ed07b6d4508805ccf319462c06ee1e232df9f5f9d0da88" target="_blank"><strong>Casaravilla, Cecilia</strong></a>
Source
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Protein Cell v.14, n°2, 2023. -- pp. 87-104
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<p><strong>Información sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislación uruguaya protege el derecho</strong> de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.</p>
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PDF
Extent
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18 p.
Language
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Inglés
Type
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Artículo
Identifier
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10.1093/procel/pwac023
Célula Dendrítica
Echinococcus
Macrógafo
Mucinas