<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/">
<rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6838">
    <dcterms:title><![CDATA[<strong>The acute inflammatory potential of particles from the Echinococcus granulosus laminated layer is moderated by its calcium inositol Hexakisphosphate component.</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[EQUINOCOCOSIS QUISTICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[ECHINOCOCCUS GRANULOSUS]]></dcterms:subject>
    <dcterms:subject><![CDATA[INFLAMACI&Oacute;N]]></dcterms:subject>
    <dcterms:subject><![CDATA[MUCINAS]]></dcterms:subject>
    <dcterms:subject><![CDATA[INOSITOL]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2024]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Cystic echinococcosis is caused by the tissue-dwelling larva (hydatid) of Echinococcus granulosus sensu lato. A salient feature is that this larva is protected by the acellular laminated layer (LL). As the parasite grows, the LL sheds abundant particles that can accumulate in the parasite's vicinity. The potential of LL particles to induce inflammation in vivo has not been specifically analysed. It is not known how each of its two major components, namely highly glycosylated mucins and calcium inositol hexakisphosphate (InsP6) deposits, impacts inflammation induced by the LL as a whole. In this work, we show that LL particles injected intraperitoneally cause infiltration of eosinophils, neutrophils and monocytes/macrophages as well as the disappearance of resident (large peritoneal) macrophages. Strikingly, the absence of calcium InsP6 enhanced the recruitment of all the inflammatory cell types analysed. In contrast, oxidation of the mucin carbohydrates caused decreased recruitment of neutrophils. The carbohydrate-oxidised particles caused cell influx nonetheless, which may be explained by possible receptor-independent effects of LL particles on innate immune cells, as suggested by previous works from our group. In summary, LL particles can induce acute inflammatory cell recruitment partly dependent on its mucin glycans, and this recruitment is attenuated by the calcium InsP6 component.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Grezzi, Leticia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Gonz&aacute;lez, Carlos</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>D&iacute;az, Alvaro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Casaravilla, Cecilia</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Parasite Immunology v. 46, n&deg; 5, 2024. -- e13040]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley]]></dcterms:publisher>
    <dcterms:date><![CDATA[2024]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong>&nbsp;de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:extent><![CDATA[6 p.]]></dcterms:extent>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[10.1111/pim.13040]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6647">
    <dcterms:title><![CDATA[<strong>One scaffold, two conformations: the ring-flip of the messenger InsP8 occurs under cytosolic conditions</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[INOSITOL]]></dcterms:subject>
    <dcterms:subject><![CDATA[INTERRUPTOR MOLECULAR]]></dcterms:subject>
    <dcterms:subject><![CDATA[DETECCION DE PH]]></dcterms:subject>
    <dcterms:subject><![CDATA[RESONANCIA MAGNETICA NUCLEAR]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2023]]></dcterms:subject>
    <dcterms:abstract><![CDATA[Inositol poly- and pyrophosphates (InsPs and PP-InsPs) are central eukaryotic messengers. These very highly phosphorylated molecules can exist in two distinct conformations, a canonical one with five phosphoryl groups in equatorial positions, and a &ldquo;flipped&rdquo; conformation with five axial substituents. Using 13C-labeled InsPs/PP-InsPs, the behavior of these molecules was investigated by 2D-NMR under solution conditions reminiscent of a cytosolic environment. Remarkably, the most highly phosphorylated messenger 1,5(PP)2 -InsP4 (also termed InsP8 ) readily adopts both conforma tions at physiological conditions. Environmental factors&mdash;such as pH, metal cation composition, and temperature&mdash;strongly influence the conformational equilibrium. Thermodynamic data revealed that the transition of InsP8 from the equatorial to the axial conformation is, in fact, an exothermic process. The speciation of InsPs and PP-InsPs also affects their interaction with protein binding partners; addition of Mg2+ decreased the binding constant Kd of InsP8 to an SPX protein domain. The results illustrate that PP-InsP speciation reacts very sensitively to solution conditions, suggesting it might act as an environment-responsive molecular switch.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Kurz, Leonie</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Schmieder, Peter</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a href="https://export.cvuy.uy/cv/?5ad3267f4b4cb5190a6d9a3f5877923f528b6603e8a436c2005a31c5f35cd644629532a16ae958823cff6464fe03287baebd3b8724cc14f8d05da74957fe496d" target="_blank"><strong>Veiga, Nicol&aacute;s</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fiedler, Dorothea</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Biomolecules, v.13, 2023. -- e645]]></dcterms:source>
    <dcterms:publisher><![CDATA[MDPI]]></dcterms:publisher>
    <dcterms:date><![CDATA[2023]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong>&nbsp;de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong>&nbsp;La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:extent><![CDATA[20 p.]]></dcterms:extent>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[10.3390/biom13040645]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/6127">
    <dcterms:title><![CDATA[<strong>myo-inositol hexakisphosphate: coordinative versatility of a natural product</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[INOSITOL
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    <dcterms:subject><![CDATA[COMPLEJOS POLINUCLEARES
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    <dcterms:subject><![CDATA[CATIONES-INTERACCION
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    <dcterms:subject><![CDATA[ESTRUCTURA CRISTALINA
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    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA
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    <dcterms:subject><![CDATA[2020
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    <dcterms:abstract><![CDATA[myo-inositol phosphates are an important group of biomolecules that are present in the eukaryotic cells. The most abundant member of this family in nature is InsP6, usually called phytate. The importance of the interaction of InsP6 with cations has been recognized during the last years, and any attempt to know the function of this molecule in eukaryotic cells must include the fact that phytate will be strongly associated with simple inorganic and organic ammonium cations in solution. On the other hand, slightly soluble salts play an important role in phosphorous storage in plant kingdom and organophosphates found in soils. This review compiles the efforts during the last ten years to quantify and understand the interaction of InsP6 with different cations, either in solution or in the formation of solid phases. A coordination chemistry&rsquo;s view is used to describe the interaction of this versatile ligand with cations and organic amines, and how they can determine the self-assembly process in the formation of polynuclear complexes and solid phases
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    <dcterms:creator><![CDATA[<strong>Kremer, Carlos</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Torres, Julia</strong>
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    <dcterms:creator><![CDATA[<strong>Bianchi, Antonio</strong>
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    <dcterms:creator><![CDATA[<strong>Savastano, Matteo</strong>
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    <dcterms:creator><![CDATA[<strong>Bazicaluppi, Carla</strong>
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    <dcterms:source><![CDATA[Coordination Chemistry Reviews v. 419, 2020. -- p. 1-19.--e213403
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    <dcterms:publisher><![CDATA[Elsevier
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    <dcterms:date><![CDATA[2020
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    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong> (Por favor lea este aviso antes de abrir los documentos u objetos)<strong> La legislaci&oacute;n uruguaya protege el derecho de autor </strong>sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>
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    <dcterms:format><![CDATA[Pdf
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    <dcterms:language><![CDATA[Ingl&eacute;s
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    <dcterms:type><![CDATA[Pdf
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    <dcterms:identifier><![CDATA[https://doi.org/10.1016/j.ccr.2020.213403
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</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/4493">
    <dcterms:title><![CDATA[<strong>Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[INOSITOL]]></dcterms:subject>
    <dcterms:subject><![CDATA[REGULADORES CELULARES]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:subject><![CDATA[2016]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The inositol pyrophosphate messengers (PP-InsPs) are emerging as an important class of cellular regulators. These molecules have been linked to numerous biological processes, including insulin secretion and cancer cell migration, but how they trigger such a wide range of cellular responses has remained unanswered in many cases. Here, we show that the PP-InsPs exhibit complex speciation behaviour and propose that a unique conformational switching mechanism could contribute to their multifunctional effects. We synthesised non-hydrolysable bisphosphonate analogues and crystallised the analogues in complex with mammalian PPIP5K2 kinase. Subsequently, the bisphosphonate analogues were used to investigate the protonation sequence, metal-coordination properties, and conformation in solution. Remarkably, the presence of potassium and magnesium ions enabled the analogues to adopt two different conformations near physiological pH. Understanding how the intrinsic chemical properties of the PP-InsPs can contribute to their complex signalling outputs will be essential to elucidate their regulatory functions.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong>Hager, Anastasia</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wu, Mingxuan</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Wang, Huanchen</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Brown, Nathaniel W. Jr.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Shears, Sthepen B.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<a title="Curriculum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=f31ba94f764507db0d42d457038dd734" target="_blank"><strong>Veiga, Nicol&aacute;s</strong></a>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Fiedler, Dorothea</strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Chemistry - A European Journal v. 22, no. 35, 2016. -- p. 12406-12414]]></dcterms:source>
    <dcterms:publisher><![CDATA[Wiley]]></dcterms:publisher>
    <dcterms:date><![CDATA[2016]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho de</strong> autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong> ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingl&eacute;s]]></dcterms:language>
    <dcterms:type><![CDATA[Art&iacute;culo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI:10.1002/chem.201601754]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://riquim.fq.edu.uy/items/show/1564">
    <dcterms:title><![CDATA[<strong>The behaviour of inositol 1,3,4,5,6-pentaleis phosphate in the presence of the major biological metal cations</strong>]]></dcterms:title>
    <dcterms:subject><![CDATA[FOSFATOS]]></dcterms:subject>
    <dcterms:subject><![CDATA[INOSITOL]]></dcterms:subject>
    <dcterms:subject><![CDATA[HIERRO]]></dcterms:subject>
    <dcterms:subject><![CDATA[CALCIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[MAGNESIO]]></dcterms:subject>
    <dcterms:subject><![CDATA[2009]]></dcterms:subject>
    <dcterms:subject><![CDATA[BIBLIOGRAFIA NACIONAL QUIMICA]]></dcterms:subject>
    <dcterms:abstract><![CDATA[The inositol phosphates are ubiquitous metabolites in eukaryotes, of which the most abundant are inositol hexakisphosphate (InsP6) and inositol 1,3,4,5,6-pentakisphosphate [Ins(1,3,4,5,6)P5)]. These two compounds, poorly understood functionally, have complicated complexation and solid formation behaviours with multivalent cations. For InsP6, we have previously described this chemistry and its biological implications (Veiga et al. in J Inorg Biochem 100:1800, 2006; Torres et al. in J Inorg Biochem 99:828, 2005). We now cover similar ground for Ins(1,3,4,5,6)P5, describing its interactions in solution with Na?, K?, Mg2?, Ca2?, Cu2?, Fe2? and Fe3?, and its solid-formation equilibria with Ca2? and Mg2?. Ins(1,3,4,5,6)P5 forms soluble complexes of 1:1 stoichiometry with all multivalent cations studied. The affinity for Fe3? is similar to that of InsP6 and inositol 1,2,3-trisphosphate, indicating that the 1,2,3- trisphosphate motif, which Ins(1,3,4,5,6)P5 lacks, is not absolutely necessary for high-affinity Fe3? complexation by inositol phosphates, even if it is necessary for their prevention of the Fenton reaction. With excess Ca2? and Mg2?, Ins(1,3,4,5,6)P5 also forms the polymetallic complexes [M4(H2L)] [where L is fully deprotonated Ins(1,3,4,5,6)P5]. However, unlike InsP6, Ins(1,3,4,5,6)P5 is predicted not to be fully associated with Mg2? under simulated cytosolic/ nuclear conditions. The neutral Mg2? and Ca2? complexes have significant windows of solubility, but they precipitate as [Mg4(H2L)]23H2O or [Ca4(H2L)]16H2O whenever they exceed 135 and 56 lM in concentration, respectively. Nonetheless, the low stability of the [M4(H2L)] complexes means that the 1:1 species contribute to the overall solubility of Ins(1,3,4,5,6)P5 even under significant Mg2? or Ca2? excesses. We summarize the solubility behaviour of Ins(1,3,4,5,6)P5 in straightforward plots]]></dcterms:abstract>
    <dcterms:creator><![CDATA[<strong><a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=f31ba94f764507db0d42d457038dd734" target="_blank">Veiga, Nicol&aacute;s</a></strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong><a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=b1b8a8c8b1a5835b874ac1994003c38d" target="_blank">Torres, Julia</a></strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Godage, Himali Y.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Riley, Andrew M.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Dom&iacute;nguez, Sixto</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>Potter, Barry V. L.</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong>D&iacute;az, Alvaro</strong>]]></dcterms:creator>
    <dcterms:creator><![CDATA[<strong><a title="Curr&iacute;culum Vitae" href="http://buscadores.anii.org.uy/buscador_sni/exportador/ExportarPdf?hash=6f16399c452f7b13f8a01a148cb38e12" target="_blank">Kremer, Carlos</a></strong>]]></dcterms:creator>
    <dcterms:source><![CDATA[Journal of Biological Inorganic Chemistry 2009 14:1001&ndash;1013]]></dcterms:source>
    <dcterms:publisher><![CDATA[Springer]]></dcterms:publisher>
    <dcterms:date><![CDATA[2009]]></dcterms:date>
    <dcterms:rights><![CDATA[<p><strong>Informaci&oacute;n sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislaci&oacute;n uruguaya protege el derecho</strong> de autor sobre toda creaci&oacute;n literaria, cient&iacute;fica o art&iacute;stica, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeci&oacute;n a lo establecido por el derecho com&uacute;n y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptaci&oacute;n de las siguientes condiciones de uso: Este documento es &uacute;nicamente para usos privados enmarcados en actividades de investigaci&oacute;n y docencia. No se autoriza su reproducci&oacute;n con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilizaci&oacute;n o cita de partes debe indicarse el nombre de la persona autora.</p>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[Ingles]]></dcterms:language>
    <dcterms:type><![CDATA[Artículo]]></dcterms:type>
    <dcterms:identifier><![CDATA[DOI 10.1007/s00775-009-0510-z]]></dcterms:identifier>
</rdf:Description></rdf:RDF>
