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https://riquim.fq.edu.uy/files/original/306999913918dd7887244eed5cd3220e.pdf
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Omeka Image File
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Bit Depth
8
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200
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Dublin Core
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Title
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Bibliografía Nacional Química
Description
An account of the resource
Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.
Contributor
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Departamento de Documentación y Biblioteca
RIQUIM
Document
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Original Format
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PDF
Dublin Core
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Title
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<p><strong>Heterocyclic-2-carboxylic acid (3-cyano-1,4-di-N-oxidequinoxalin-2-yl)amide derivatives as hits for the development of neglected disease drugs</strong></p>
Subject
The topic of the resource
TRYPANOSOMA CRUZI
TUBERCULOSIS
COMPUESTOS HETEROCICLICOS
QUINOXALINA
BIBLIOGRAFIA NACIONAL QUIMICA
2009
Abstract
A summary of the resource.
Neglected diseases represent a major health problem. It is estimated that one third of the world population is infected with tuberculosis (TB). Besides TB, Chagas disease, affects approximately 20 million people. Quinoxalines display great activities against TB and Chagas. Forty new quinoxaline 1,4-di-N-oxide derivatives have been prepared and tested against M. tuberculosis and T. cruzi. Carboxylic acid quinoxaline 1,4-di-N-oxides (CAQDOs) 5 and 17 showed MIC values on the same order as the reference antituberculosis drug, rifampicin. Meanwhile, CAQDOs 12 and 22 presented IC50 values in the same order as the anti-chagasic drug, nifurtimox.
Creator
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<strong>Ancizu, Saioa</strong>
<strong>Moreno, Elsa</strong>
<strong>Torres, Enrique</strong>
<strong>Burguete, Asunción</strong>
<strong>Pérez-Silanes, Silvia</strong>
<strong>Benítez, Diego</strong>
<strong>Villar, Raquel</strong>
<strong>Solano, Beatriz</strong>
<strong>Marín, Adoración</strong>
<strong>Aldana, Ignacio</strong>
<strong>Cerecetto, Hugo</strong>
<strong>González Hormaizteguy, María Mercedes</strong>
<strong>Monge, Antonio</strong>
Source
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Molecules (Basel, Switzerland) v.14, no. 6, 2009. -- p.2256-2272
Publisher
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MDPI
Date
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2009
Type
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Artículo
Identifier
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doi: 10.3390/molecules14062256.
Química
Quinoxalina
-
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Omeka Image File
The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files.
Bit Depth
8
Channels
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https://riquim.fq.edu.uy/files/original/b29d3174defdb21dc1d65919795edb70.pdf
00856400ed20b3ff9ad90ff1d68f3dcc
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Bibliografía Nacional Química
Description
An account of the resource
Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.
Contributor
An entity responsible for making contributions to the resource
Departamento de Documentación y Biblioteca
RIQUIM
Document
A resource containing textual data. Note that facsimiles or images of texts are still of the genre text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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<strong>Quinoxaline derivatives : A patent review (2006 present)</strong>
Subject
The topic of the resource
HETEROCICLOS
QUINOXALINA
BIBLIOGRAFIA NACIONAL QUIMICA
2012
Abstract
A summary of the resource.
Introduction: Quinoxaline scaffold is included in a large number of therapeutic agents because of its physicochemical properties that make the difference between them and the carbono analogue, naphthalene. Areas covered: This review of patented products presents the quinoxaline 10 heterocycle as part of the structural patent claims from a medicinal chemistry perspective. Expert opinion: We centred our discussion in the various drug patent applications of the quinoxaline and its derivatives. The applications are based firstly in the specific enzyme target with very low development in the disease 15 treatment. Only for cancer and antimicrobial agents they were specifically determined but little is mentioned in order to insight in the last development activities.
Creator
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<strong>González Hormaizteguy, María Mercedes</strong>
<strong>Cerecetto, Hugo</strong>
Source
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Expert Opinion on Therapeutic Patents . v.12, no. 11, 2012. -- p.1289-1302
Publisher
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Informa Healthcare
Date
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2012
Rights
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<p><strong>Información sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislación uruguaya</strong> protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes</p>
<p>(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA</strong> - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.</p>
<p> </p>
Format
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PDF
Language
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Inglés
Type
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Artículo
Identifier
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ISSN 1354-3776
Heterociclos
Quinoxalina