1
25
4
-
https://riquim.fq.edu.uy/files/original/03c97088eb0d2d0964a66b2a6a94bec8.PNG
f6df4c7534d8bae0169a5dbabddc08e8
https://riquim.fq.edu.uy/files/original/fd2b44ba9dcf95c109954a9002dc210d.pdf
c845c1000b6329c094a98acfecd6b7ea
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Bibliografía Nacional Química
Description
An account of the resource
Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.
Contributor
An entity responsible for making contributions to the resource
Departamento de Documentación y Biblioteca
RIQUIM
Document
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Original Format
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PDF
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Title
A name given to the resource
<strong>Chitosan double-stranded RNA nanocomplexes for Piezodorus guildinii control</strong>
Subject
The topic of the resource
ARNi
ARN DE INTERFERENCIA
CHINCHES
HEMIPTEROS
SILENCIAMIENTO GENICO
QUITOSANO
BIBLIOGRAFIA NACIONAL QUIMICA
2025
Abstract
A summary of the resource.
BACKGROUND: Piezodorus guildinii (Westwood, Hemiptera: Pentatomidae) causes economic losses in soybean crops by diminishing productivity, impacting grain size, oil content, and germination power. RNA interference (RNAi), a conserved gene regulation process initiated by double-stranded RNA (dsRNA), may be used as a safe technique in integrated pest management strategies. Conjugating dsRNA with cationic polymers, which protect dsRNA from degradation has shown to enhance this response. This study aims to assess the impact of dsRNA administration on the viability of P. guildinii and evaluate dsRNAchitosan nanocomplexes as a pest control strategy. RESULTS: Ten target genes were selected, dsRNAs were designed and synthesized. In injection assays, significant mortality exceeding 76% was observed, while mortality from ingestion also showed significant differences, reaching 49%. The dsRNA targeting Srp54k gene was selected and a chitosan-dsRNA nanocomplex was synthesized. These nanocomplexes demonstrated enhanced stability under RNase treatment in vitro, and, in in vivo assays, a cumulative corrected mortality rate of 66% was reported. Consistent with these findings, RT-qPCR analysis revealed that gene expression levels in treated insects were significantly reduced compared to control at 24, 48, and 72 h post treatment for targeted genes. CONCLUSION: In this work, we evaluated the effect of dsRNA administration by injection and ingestion on the viability of P. guildinii and determined its molecular silencing effects. Additionally, we synthesized and characterized chitosan-dsRNA nanoparticles, which demonstrated improved efficacy in terms of stability. These findings are promising for the development of new integrated management strategies for stink bugs control.
Creator
An entity primarily responsible for making the resource
<strong>Schvartzman, Claudia</strong>
<strong>Murchio, Sara</strong>
<a href="https://export.cvuy.uy/cvsni/?urlId=941db2fb37d37b9ad1d5d5076b50e2d3434e0c811b1525d45f4d28e6502cd7023186b4c4f48a6fa014b6e7015df5fb7104e161a1e4aeb4d7788dfe84a9596fc1&convocatoria=21&formato=html"><strong>Castro, Analía</strong></a>
<a href="https://export.cvuy.uy/cvsni/?urlId=9364ac87c2ec6c8d9758118d5259215a7ee81b13f851bb0a6f93fd28b63c50a05744d23e624729067c77ddf36abbec16e5e9efe430647b46c12697dda2ac26c3&convocatoria=21&formato=html"><strong>Cibils, Ximena</strong></a>
<strong>Miranda, Pablo</strong>
<strong>Mujica, María Valentina</strong>
<a href="https://export.cvuy.uy/cv/?90f8063f5d45d26487d94d93e9a22f454ec683bc1f137c80f0fce2ce741c123056026e93ea9c7f332f3a3d817c4c3ccd5a917070aab1f3fed4529ecff28b5dc4"><strong>Pardo, Helena</strong></a>
<strong>Dalla-Rizza, Marco</strong>
Source
A related resource from which the described resource is derived
Pest Management Science, v. 81, n°7, 2025. -- pp. 3774-3785
Publisher
An entity responsible for making the resource available
Society of Chemical Industry
Date
A point or period of time associated with an event in the lifecycle of the resource
2025
Rights
Information about rights held in and over the resource
<p><strong>Información sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislación uruguaya protege el derecho</strong> de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.</p>
Format
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PDF
Extent
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12 p.
Language
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Inglés
Type
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Artículo
Identifier
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10.1002/ps.8744
ARN de interferencia
ARNi
Chinches
Hemípteros
Quitosano
Silenciamiento génico
-
https://riquim.fq.edu.uy/files/original/5ee215507074d4191b209f754a0287ac.pdf
c845c1000b6329c094a98acfecd6b7ea
https://riquim.fq.edu.uy/files/original/4070ca55a30f7817f7beb1addb328ce4.jpg
ba5c789a5713d3bab8add50f972b3e11
Omeka Image File
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8
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3
Height
155
Width
116
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Bibliografía Nacional Química
Description
An account of the resource
Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.
Contributor
An entity responsible for making contributions to the resource
Departamento de Documentación y Biblioteca
RIQUIM
Document
A resource containing textual data. Note that facsimiles or images of texts are still of the genre text.
Original Format
If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data
PDF
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
<strong><span data-sheets-formula-bar-text-style="font-size:13px;color:#000000;font-weight:normal;text-decoration:none;font-family:'Arial';font-style:normal;text-decoration-skip-ink:none;">Formulating a TMEM176B blocker in chitosan nanoparticles uncouples its paradoxical roles in innate and adaptive antitumoral immunity</span></strong>
Subject
The topic of the resource
NANOPARTICULAS
QUITOSANO
TMEM176B
INFLAMASOMA
INMUNIDAD TUMORAL
NANOENCAPSULACION
BIBLIOGRAFIA NACIONAL QUIMICA
2024
Abstract
A summary of the resource.
The immunoregulatory cation channel TMEM176B plays a dual role in tumor immunity. On the one hand, TMEM176B promotes antigen cross-presentation to CD8+ T cells by regulating phagosomal pH in dendritic cells (DCs). On the other hand, it inhibits NLRP3 inflammasome activation through ionic mechanisms in DCs, monocytes and macrophages. We speculated that formulating BayK8644 in PEGylated chitosan nanoparticles (NP-PEG-BayK8644) should slowly release the compound and by that mean avoid cross-presentation inhibition (which happens with a fast 30 min kinetics) while still triggering inflammasome activation. Chitosan nanocarriers were successfully obtained, exhibiting a particle size within the range of 200 nm; they had a high positive surface charge and a 99 % encapsulation efficiency. In in vitro studies, NP-PEG-BayK8644 did not inhibit antigen cross-presentation by DCs, unlike the free compound. The NP-PEG-BayK8644 activated the inflammasome in a Tmem176b-dependent manner in DCs. We administered either empty (eNP-PEG) or NP-PEGBayK8644 to mice with established tumors. NP-PEG-BayK8644 significantly controlled tumor growth and improved mice survival compared to both eNP-PEG and free BayK8644 in melanoma and lymphoma models. This effect was associated with enhanced inflammasome activation by DCs in the tumor-draining lymph node and infiltration of the tumor by CD8+ T cells. Thus, encapsulation of BayK8644 in chitosan NPs improves the anti-tumoral properties of the compound by avoiding inhibition of antigen cross-presentation.
Creator
An entity primarily responsible for making the resource
<strong>Victoria, Sabina</strong><br /><br />
<strong>Castro, Analía</strong><br /><br />
<strong>Pittini, Alvaro</strong><br /><br />
<strong>Olivera, Daniela</strong><br /><br />
<strong>Russo, Sofía</strong><br /><br />
<strong>Cebrian, Ignacio</strong><br /><br />
<strong>Mombru, Alvaro W.</strong><br /><br />
<strong>Osinaga, Eduardo</strong><br /><br />
<strong>Pardo, Helena</strong><br /><br />
<strong>Segovia, Mercedes</strong><br /><br />
<strong>Hill, Marcelo</strong>
Source
A related resource from which the described resource is derived
<span data-sheets-formula-bar-text-style="font-size:13px;color:#000000;font-weight:normal;text-decoration:none;font-family:'Arial';font-style:normal;text-decoration-skip-ink:none;">International Journal of Biological Macromolecules, v. 279, nº 3, 2024. -- e135327</span>
Publisher
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Elsevier
Date
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2024
Rights
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<div class="element-text">
<p><strong>Información sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislación uruguaya protege el derecho</strong> de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.</p>
</div>
Format
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PDF
Extent
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11 p.
Language
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Inglés
Type
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Artículo
Identifier
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<span data-sheets-formula-bar-text-style="font-size:13px;color:#000000;font-weight:normal;text-decoration:none;font-family:'Arial';font-style:normal;text-decoration-skip-ink:none;">10.1016/j.ijbiomac.2024.135327</span>
Inflamasoma
Inmunidad tumoral
Nanoencapsulación
Nanopartículas
Quitosano
TMEM176B
-
https://riquim.fq.edu.uy/files/original/fdfde5b75733f47008523d98d5becb1d.pdf
c845c1000b6329c094a98acfecd6b7ea
https://riquim.fq.edu.uy/files/original/fc2d16cfa4ea818458573962b411c0bc.jpg
906b61b2c205608ce7ea7d25cec3007f
Omeka Image File
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8
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3
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155
Width
115
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Title
A name given to the resource
Bibliografía Nacional Química
Description
An account of the resource
Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.
Contributor
An entity responsible for making contributions to the resource
Departamento de Documentación y Biblioteca
RIQUIM
Document
A resource containing textual data. Note that facsimiles or images of texts are still of the genre text.
Original Format
If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data
PDF
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
<strong>Development and characterization of chitosan-silver nanohybrids with potential application in the control of fungal phytopathogens</strong>
Subject
The topic of the resource
QUITOSANO
FITOPATOGENOS
NANOPARTICULAS DE PLATA
AGENTES ANTIFUNGICOS
ACTIVIDAD ANTIMICROBIANA
PLANTAS
INFECCIONES MICROBIANAS
BIBLIOGRAFIA NACIONAL QUIMICA
2023
Abstract
A summary of the resource.
In the agricultural field, chitosan (CS) is of great interest due to their broad antimicrobial activity and their ability to induce resistance mechanisms in plants against phytopathogens. Likewise, the potential of silver nanoparticles in preventing microbial infections has been demonstrated, including their broad antimicrobial activity against phytopathogens. In this study, the synthesis and characterization of chitosan-silver nanohybrids were performed. Firstly, mycosynthesis of biogenic silver nanoparticles (PchNPs) was carried out. Subsequently, the nanohybrid (CS-PchNHs) synthesis involved the addition of PchNPs, with continuous stirring, into a CS solution. For the first-time stable CS-Pch NHs were produced using biogenic silver nanoparticles from the fungus Phanerochaete chrysosporium, characterized by UV-visible spectroscopy (UV-Vis), Dynamic Light Scattering, (DLS), ζ-Potential, and X- ray diffraction (XRD). Additionally, CS-PchNHs exhibited high antifungal activity at low concentrations against four phytopathogens, suggesting that these nanosystems may be used as an alternative to the current hazardous antifungal agents in the integrated disease management.
Creator
An entity primarily responsible for making the resource
<strong>Vásquez, Noheilly</strong>
<strong>Elizalde, Valeria</strong>
<strong>Castro, Analía</strong>
<strong>Miraballes, Iris</strong>
<strong>Pardo, Helena</strong>
<strong>Alborés, Silvana</strong>
Source
A related resource from which the described resource is derived
MRS Advances, 2023. --
Publisher
An entity responsible for making the resource available
Springer
Date
A point or period of time associated with an event in the lifecycle of the resource
2023
Rights
Information about rights held in and over the resource
<div class="element-text">
<p><strong>Información sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislación uruguaya protege el derecho</strong> de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.</p>
</div>
Format
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PDF
Extent
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6 p.
Language
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Inglés
Type
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Artículo
Identifier
An unambiguous reference to the resource within a given context
10.1557/s43580-023-00650-x
Actividad antimicrobiana
Agentes antifúngicos
Fitópatogenos
Infecciones microbianas
Nanopartículas de plata
Plantas
Quitosano
-
https://riquim.fq.edu.uy/files/original/93e8221e7830427b68bd8a3e8411a2b4.pdf
381081c6197b4d45a931a88b922a3eeb
https://riquim.fq.edu.uy/files/original/39f1e0e6d4f039d3cc63fc7a5c84f5f1.gif
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Omeka Image File
The metadata element set that was included in the `files_images` table in previous versions of Omeka. These elements are common to all image files.
Bit Depth
8
Channels
3
Height
150
Width
113
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Bibliografía Nacional Química
Description
An account of the resource
Contiene la producción científica nacional de los profesionales químicos e investigadores, durante el período 1929 hasta la fecha.
Contributor
An entity responsible for making contributions to the resource
Departamento de Documentación y Biblioteca
RIQUIM
Document
A resource containing textual data. Note that facsimiles or images of texts are still of the genre text.
Original Format
If the image is of an object, state the type of object, such as painting, sculpture, paper, photo, and additional data
PDF
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
<strong>Physico-chemical and antilisterial properties of nisin-incorporated chitosan/ carboxymethyl chitosan films</strong>
Subject
The topic of the resource
POLIMEROS NATURALES
PROPIEDADES FISICOQUIMICAS
QUITOSANO
LISTERIA
BIBLIOGRAFIA NACIONAL QUIMICA
2019
Abstract
A summary of the resource.
The objective of this work was to investigate the effect of the addition of carboxymethyl chitosan on the structural properties and antilisterial activity of nisin-incorporated chitosan films. Chitosan and carboxymethyl chitosan solutions were prepared with different mass ratios and bacteriocin nisin was added (0, 1000 and 6000 IU/ml). Filmogenic solutions were cast, dried and their physico-chemical and antimicrobial properties were investigated. For the same chitosan/carboxymethyl chitosan mass ratio, the addition of NIS at 6000 IU/ml led to changes in the macro- and microstructure, as well as in physico-chemical properties of films. On the other hand, carboxymethyl chitosan had a plasticizing effect and enhanced the distribution of the bacteriocin within the biopolymer matrix. Moreover, nisin-incorporated blend films of chitosan and carboxymethyl chitosan were more effective against Listeria monocytogenes than their pure chitosan counterparts. This study showed that different formulations of nisin-incorporated composite films of chitosan and carboxymethyl chitosan may provide options for developing bioactive packaging to improve food safety.
Creator
An entity primarily responsible for making the resource
<strong>Zimet, Patricia</strong>
<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=2ahUKEwiVtLys47_mAhXwI7kGHSpbBwoQFjAAegQIBBAH&url=https%3A%2F%2Fexportcvuy.anii.org.uy%2Fpdf%2F%3F1b0a087e3c87093cbc890b5bf91c399442e82cecc6f88c2cf9bc2d893c994b60b23ca38b16378acce4a04af7b21e8aad8d2952e078de5c23f190942588f4006c&usg=AOvVaw1cgmLYl82PH1jNuQyaHyI0" target="_self"><strong>Mombrú, Álvaro W.</strong></a>
<strong>Mombrú, Dominique</strong>
<strong>Castro, Analía.</strong>
<strong>Villanueva, Juan Pablo</strong>
<a title="Curriculum Vitae" href="https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=2ahUKEwjfjr3D5b_mAhUPK7kGHamgDVoQFjAAegQIBxAH&url=https%3A%2F%2Fexportcvuy.anii.org.uy%2FCvEstatico%2F%3FurlId%3D90f8063f5d45d26487d94d93e9a22f454ec683bc1f137c80f0fce2ce741c123056026e93ea9c7f332f3a3d817c4c3ccd5a917070aab1f3fed4529ecff28b5dc4%26formato%3Dpdf%26convocatoria%3D21&usg=AOvVaw07fmaw4SxSWCo3MfsVfmVT" target="_self"><strong>Pardo, Helena</strong></a>
<strong>Rufo, Caterina</strong>
Source
A related resource from which the described resource is derived
Carbohydrate Polymers v. 219, 2019. -- p. 334-343
Publisher
An entity responsible for making the resource available
Elsevier
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
Rights
Information about rights held in and over the resource
<p><strong>Información sobre Derechos de Autor</strong></p>
<p>(Por favor lea este aviso antes de abrir los documentos u objetos)</p>
<p><strong>La legislación uruguaya</strong> protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)</p>
<p><strong>ADVERTENCIA -</strong> La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.</p>
Format
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Pdf
Language
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Inglés
Type
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Artículo
Identifier
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DOI:10.1016/j.carbpol.2019.05.013
Listeria
Polimeros Naturales
Propiedades fisicoquímicas
Quitosano