Study of the effects of operational parameters on multiresidue pesticide analysis by LC-MS/MS

Dublin Core

Título

Study of the effects of operational parameters on multiresidue pesticide analysis by LC-MS/MS

Tema

PLAGUICIDAS
ESPECTROSCOPIA DE MASA
RESIDUOS DE PLAGUICIDAS
ANALISIS DE ALIMENTOS
CROMATOGRAFIA LIQUIDA
BIBLIOGRAFIA NACIONAL QUIMICA
2011

Abstract

In this paper, the influence of several operational parameters on a well established multiresidue LC–MS/MS method has been studied in relation to the analysis of 150 pesticides commonly present in vegetable samples. The operational parameters investigated are: (i) the influence of different modifiers (0.1% formic acid; 5mMammonium formiate; 5mMammonium acetate in aqueous phase) – both on the retention time and on the analytical response of the studied compounds; (ii) the effect of the analytical column’s temperature on the retention time and on the analytical response of the pesticides investigated; (iii) the effects of co-elution in mixture containing 150 pesticides and, additionally, (iv) the carrying out of a study about the common transitions obtained by LC–MS/MS. Various common transitions were found among the 150 pesticides, but there were only two problematic cases, the pairs diuron–fluometuron and prometryn–terbutryn, which have common scanned transitions and have very close retention times. The use of ammonium salts as modifier instead of formic acid reports enhancement or suppression of the response depending on the pesticides. No great influence on the retention time or on the response of the pesticides and commodities studied was observed with relation to the column temperature. Two different columns: an HPLC (5m particle size) and an UHPLC analytical column (1.8m particle size) have been used. As was expected, shorter run times and lower peak width was achieved with the UHPLC column. In this paper, the effect of the compounds on each other in the MS analysis when the number of coeluting compounds is quite high is also described. Mainly small suppression or enhancement co-elution effect was observed, but some particular pesticides presented high sensitivity (>±60% effect) when they elute together with others. This is an important factor and it has to be taken into account when performing multiresidue pesticide analysis.

Autor

Kmellár, B.
Ferrer, C.
Fodor, P.
Fernández-Alba, A. R.

Fuente

Talanta v. 84, no 2, 2011. --p. 262-273

Editor

Elsevier

Fecha

2011

Derechos

Información sobre Derechos de Autor

(Por favor lea este aviso antes de abrir los documentos u objetos)

La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes

(LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006)

ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.

Formato

PDF

Idioma

Inglés

Tipo

Artículo

Identificador

doi:10.1016/j.talanta.2010.12.006
Fecha de agregación
September 2, 2013
Colección
Bibliografía Nacional Química
Tipo de Elemento
Document
Etiquetas
, , , ,
Citación
Kmellár, B., “Study of the effects of operational parameters on multiresidue pesticide analysis by LC-MS/MS,” RIQUIM - Repositorio Institucional de la Facultad de Química - UdelaR, accessed September 15, 2019, http://riquim.fq.edu.uy/items/show/874.
Archivos