Drinking water lead, iron and zinc concentrations as predictors of blood lead levels and urinary lead excretion in school children from Montevideo, Uruguay

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Título

Drinking water lead, iron and zinc concentrations as predictors of blood lead levels and urinary lead excretion in school children from Montevideo, Uruguay

Tema

PLOMO
BIOMARCADORES
URUGUAY
EXPOSICION AL PLOMO
BIBLIOGRAFIA NACIONAL QUIMICA
2018

Abstract

The global burden of water-based lead (Pb) exposure on children is largely unknown; however, the importance of water sources as a path of Pb exposure is receiving increased attention due to recent prominent exposure events related to corroded plumbing infrastructure in the US. This study investigated the contribution of Pb in household drinking and cooking water to Pb levels in blood (PbB) and urine (PbU) within 353 early school-aged children from Montevideo, Uruguay. Additionally, the analysis considered the child's iron status and the water content of iron (WFe) and zinc (WZn) in relation to water Pb and blood/urine Pb concentrations. Lead concentrations for both PbB and PbU were fairly low (M ± SD: 4.2 ± 2.1 μg/dL; Median [5%, 95%]: 1.9 [0.6, 5.1 μg/L, respectively]); however 21% of the sample had a PbB >5 μg/dL but ≤ 10 μg/dL. Overall, there was little evidence of an association between water metal concentrations and children's PbB/PbU. However, when the sample was stratified by children's iron status, WPb was positively related to PbU, but negatively related to PbB in iron-replete children, even after adjusting for WFe and WZn. In iron-deficient children, there was no elevation in PbU with increasing WPb. In this sample of children with low Pb levels, there were no overwhelming relationships between WPb and either PbB or PbU, however, there was some evidence that iron-replete status promotes excretion of WPb.

Autor

Ravenscroft, Julia
Roy, Aditi
Queirolo, Elena I.
Martínez, Gabriela.
Peregalli, Fabiana
Kordas, Katarzyna

Fuente

Chemosphere v. 212, 2018. -- p. 694-704

Editor

Elsevier

Fecha

2018

Derechos

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PDF

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Tipo

Artículo

Identificador

DOI: 10.1016/j.chemosphere.2018.07.154

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PDF
Fecha de agregación
May 8, 2019
Colección
Bibliografía Nacional Química
Tipo de Elemento
Document
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Citación
Ravenscroft, Julia, “Drinking water lead, iron and zinc concentrations as predictors of blood lead levels and urinary lead excretion in school children from Montevideo, Uruguay,” RIQUIM - Repositorio Institucional de la Facultad de Química - UdelaR, accessed July 23, 2019, http://riquim.fq.edu.uy/items/show/5756.
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