Low level arsenic exposure, B-vitamins, and achievement among Uruguayan
school children

Dublin Core

Título

Low level arsenic exposure, B-vitamins, and achievement among Uruguayan
school children

Tema

TOXICOLOGIA
ARSENICO
VITAMINAS-B
BIBLIOGRAFIA NACIONAL QUIMICA
2020
URUGUAY
NIÑOS

Abstract

Objectives: Millions of children globally, including the U.S., are exposed to low levels of arsenic from water and food. Arsenic is a known neurotoxicant at high levels but its effects at lower exposure levels are understudied.
Arsenic methylation capacity, influenced by B-vitamin intake and status, potentially influences arsenic toxicity.
In a cross-secitonal study of 5–8 year-old children from Montevideo, we assessed the relationship between urinary arsenic (U–As) and academic achievement, and tested for effect modification by B-vitamin intake, status, and arsenic methylation capacity.
Methods: Broad math and reading scores were calculated based on six subtests (calculation, math facts fluency, applied problems, sentence reading fluency, letter word identification, passage comprehension) from the Woodcock-Muñoz Achievement Battery. B-vitamin intake was assessed from two non-consecutive 24-h dietary
recalls, serum folate and vitamin B-12 levels were measured in a subset of participants. Arsenic methylation capacity was measured as the proportion of urinary monomethylarsonic acid (%MMA). Multiple imputation using chained equations was conducted to account for missing covariate and exposure data. Ordinal regressions
assessed associations between U–As and achievement score tertiles in the complete case and imputed samples. A “B-vitamin index” was calculated using principal component analysis. Interactions by urinary %MMA and the Bvitamin
index were assessed.
Results: Median specific gravity adjusted U–As was 11.7 μg/L (range: 2.6, 50.1). We found no association between U–As and broad math and reading scores, nor effect modification by %MMA or B-vitamins.
Conclusion: At low-levels of exposure, U–As does not appear to affect children's academic achievement

Autor

Desai, Gauri

Barg, Gabriel

Vahther, Marie

Queirolo, Elena I.

Peregalli, Fabiana

Mañay, Nelly

Millen, Amy E.

Yu, Jihnhee

Browne, Richard W.

Kordas, Katarzyna

Fuente

International Journal of Hygiene and Environmental Health v. 223, 2020. --p. 124-131

Editor

Elsevier

Fecha

2020

Derechos

Información sobre Derechos de Autor (Por favor lea este aviso antes de abrir los documentos u objetos) La legislación uruguaya protege el derecho de autor sobre toda creación literaria, científica o artística, tanto en lo que tiene que ver con sus derechos morales, como en lo referente a los derechos patrimoniales con sujeción a lo establecido por el derecho común y las siguientes leyes (LEY 9.739 DE 17 DE DICIEMBRE DE 1937 SOBRE PROPIEDAD LITERARIA Y ARTISTICA CON LAS MODIFICACIONES INTRODUCIDAS POR LA LEY DE DERECHO DE AUTOR Y DERECHOS CONEXOS No. 17.616 DE 10 DE ENERO DE 2003, LEY 17.805 DE 26 DE AGOSTO DE 2004, LEY 18.046 DE 24 DE OCTUBRE DE 2006 LEY 18.046 DE 24 DE OCTUBRE DE 2006) ADVERTENCIA - La consulta de este documento queda condicionada a la aceptación de las siguientes condiciones de uso: Este documento es únicamente para usos privados enmarcados en actividades de investigación y docencia. No se autoriza su reproducción con fines de lucro. Esta reserva de derechos afecta tanto los datos del documento como a sus contenidos. En la utilización o cita de partes debe indicarse el nombre de la persona autora.

Formato

Pdf

Idioma

Inglés

Tipo

Artículo

Identificador

https://doi.org/10.1016/j.ijheh.2019.09.011

Document Item Type Metadata

Original Format

Pdf
Fecha de agregación
September 17, 2020
Colección
Bibliografía Nacional Química
Tipo de Elemento
Document
Etiquetas
, ,
Citación
Desai, Gauri, “Low level arsenic exposure, B-vitamins, and achievement among Uruguayanschool children,” RIQUIM - Repositorio Institucional de la Facultad de Química - UdelaR, accessed October 21, 2020, http://riquim.fq.edu.uy/items/show/6129.
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