RIQUIM - Repositorio Institucional de la Facultad de Química - UdelaR

High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi

Tags: Antitripanosomas, Enfermedad de chagas, Vanadio

A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes

Tags: Antitripanosomas, Productos farmacéuticos, Tripanosomiasis

Exploring oxidovanadium (IV) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents

Tags: Antitripanosomas, Leishmaniasis, Trypanosoma cruzi, Vanadio

New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents

Tags: Antitripanosomas, Enfermedad de chagas, Tripanosomiasis

New heterobimetallic ferrocenyl derivatives : Evaluation of their potential as prospective agents against trypanosomatid parasites and Mycobacterium tuberculosis

Tags: Antitripanosomas, Leishmaniasis, Tuberculosis

Trypanothione reductase : A target for the development of anti-Trypanosoma cruzi drugs

Tags: Antiparasitarios, Antitripanosomas, Productos farmacéuticos

Synthesis, crystal structure, catalytic and anti-Trypanosoma cruzi activity of a new chromium(III) complex containing bis(3,5- dimethylpyrazol-1-yl)methane

Tags: Antitripanosomas, Catálisis, Cromo, Estructura Cristalina, Síntesis

Activity on Trypanosoma cruzi, erythrocytes lysis and biologically relevant physicochemical properties of Pd(II) and Pt(II) complexes of thiosemicarbazones derived from 1-indanones

Tags: Antitripanosomas, Enfermedad de chagas, Palladio, Tripanosomiasis, Trypanosoma cruzi

Expanding the family of heteroleptic oxidovanadium(IV) compounds with salicylaldehyde semicarbazones and polypyridyl ligands showing anti-Trypanosoma cruzi activity

Tags: Antitripanosomas, G. Tripanosomiasis, Scalese, Semicarbazonas

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites

Tags: Antitripanosomas, Rutenio

Macrocycles as potential therapeutic agents in neglected diseases

Tags: Antitripanosomas, Leishmaniasis, Macrociclos

Synthetic modifications of lead compounds as antitrypanosomal drugs

Tags: Antitripanosomas, Plomo

Mass spectrometry of 1,2,5-oxadiazole N-oxide derivatives. Use of deuterated analogues in fragmentation pattern studies.

Tags: Antitripanosomas, Espectroscopía, Química

Novel antiprotozoal products : imidazole and benzimidazole N-oxide derivatives and related compounds.

Tags: Antitripanosomas, Citotoxinas, Metronidazol, Trypanosoma cruzi

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5 nitrofuryl containing thiosemicarbazones.

Tags: Antiparasitarios, Antitripanosomas, Nifurtimox

Design : synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione bindingsite of trypanothione reductase as target for rational design.

Tags: Antitripanosomas

Anti-T. cruzi activities and QSAR studies of 3-arylquinoxaline-2-carbonitrile di-N-oxides.

Tags: Antiparasitarios, Antitripanosomas, Enfermedad de chagas, Productos farmacéuticos, Trypanosoma cruzi

Theoretical EPR study of Nitroindazoles: 3-Alkoxy, 3-Hydroxy and 3-Oxo Derivatives.

Tags: Antitripanosomas, Espectroscopía, Trypanosoma cruzi

Coordination of nitro-thiosemicarbazones to ruthenium(II) as a strategy for anti-trypanosomal activity improvement.

Tags: Antitripanosomas, Complejos, Rutenio, Tiosemicarbazonas

Homology modeling of T. cruzi and L. major NADH-dependent fumarate reductases: ligand docking, molecular dynamics validation, and insights on their binding modes

Tags: Antitripanosomas, Leishmaniasis, Tripanosomiasis, Trypanosoma cruzi

Synthesis and biological characterization of new aryloxyindole-4,9-diones as potent trypanosomicidal agents

Tags: Antitripanosomas, Citotoxicidad, Tripanosomiasis

Naftifine-analogues as anti-Trypanosoma cruzi agents.

Tags: Antitripanosomas, Tripanosomiasis

In Vivo Anti-Trypanosoma cruzi Activity of Hydro-Ethanolic Extract and Isolated Active Principles from Aristeguietia glutinosa and Mechanism of Action Studies

Tags: Antitripanosomas, Aristiguietia glutinosa, Tripanosomiasis

Effect of the Metal Ion on the anti T. cruzi Activity and Mechanism of Action of 5-Nitrofuryl-Containing Thiosemicarbazone Metal Complexes

Tags: ADN, Antitripanosomas, Complejos de metales, Diseño de drogas, Metales, Paladio, Platino

Optimization of Antitrypanosomatid Agents : dentification of Nonmutagenic Drug Candidates with in Vivo Activity

Tags: Antitripanosomas, Tripanosomiasis

Browse Items (51 total)

Featured Item

Thermal analysis of the combustion of charcoals from Eucalyptus dunii obtained at different pyrolysis temperatures.

High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi

A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes

Exploring oxidovanadium (IV) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents

New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents

New heterobimetallic ferrocenyl derivatives : Evaluation of their potential as prospective agents against trypanosomatid parasites and Mycobacterium tuberculosis

Trypanothione reductase : A target for the development of anti-Trypanosoma cruzi drugs

Synthesis, crystal structure, catalytic and anti-Trypanosoma cruzi activity of a new chromium(III) complex containing bis(3,5- dimethylpyrazol-1-yl)methane

Activity on Trypanosoma cruzi, erythrocytes lysis and biologically relevant physicochemical properties of Pd(II) and Pt(II) complexes of thiosemicarbazones derived from 1-indanones

Expanding the family of heteroleptic oxidovanadium(IV) compounds with salicylaldehyde semicarbazones and polypyridyl ligands showing anti-Trypanosoma cruzi activity

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites

Macrocycles as potential therapeutic agents in neglected diseases

Synthetic modifications of lead compounds as antitrypanosomal drugs

Mass spectrometry of 1,2,5-oxadiazole N-oxide derivatives. Use of deuterated analogues in fragmentation pattern studies.

Novel antiprotozoal products : imidazole and benzimidazole N-oxide derivatives and related compounds.

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5 nitrofuryl containing thiosemicarbazones.

Design : synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione bindingsite of trypanothione reductase as target for rational design.

Anti-T. cruzi activities and QSAR studies of 3-arylquinoxaline-2-carbonitrile di-N-oxides.

Theoretical EPR study of Nitroindazoles: 3-Alkoxy, 3-Hydroxy and 3-Oxo Derivatives.

Coordination of nitro-thiosemicarbazones to ruthenium(II) as a strategy for anti-trypanosomal activity improvement.

Homology modeling of T. cruzi and L. major NADH-dependent fumarate reductases: ligand docking, molecular dynamics validation, and insights on their binding modes

Synthesis and biological characterization of new aryloxyindole-4,9-diones as potent trypanosomicidal agents

Naftifine-analogues as anti-Trypanosoma cruzi agents.

In Vivo Anti-Trypanosoma cruzi Activity of Hydro-Ethanolic Extract and Isolated Active Principles from Aristeguietia glutinosa and Mechanism of Action Studies

Effect of the Metal Ion on the anti T. cruzi Activity and Mechanism of Action of 5-Nitrofuryl-Containing Thiosemicarbazone Metal Complexes

Optimization of Antitrypanosomatid Agents : dentification of Nonmutagenic Drug Candidates with in Vivo Activity