RIQUIM - Repositorio Institucional de la Facultad de Química - UdelaR

Syntesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives.

Tags: Antichagásicos, Semicarbazonas, Síntesis, Trypanosoma cruzi

Synthesis and Antichagasic Properties of New 1,2,6-Thiadiazin-3,5-dione 1,1-Dioxides and Related compounds.

Tags: Antichagásicos, Trypanosoma cruzi

New thiadizine derivatives with activity against Trypanosoma cruzi amastigotes.

Tags: Trypanosoma cruzi

Synthesis and anti-trypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivates. Structure-activity relationships.

Tags: Actividad Atiripanosoma, Antichagásicos, Trypanosoma cruzi

Novel antiprotozoal products : imidazole and benzimidazole N-oxide derivatives and related compounds.

Tags: Antitripanosomas, Citotoxinas, Metronidazol, Trypanosoma cruzi

Quinoxaline NNï-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi. Structure activity relationships.

Tags: Antiparasitarios, Estructura cristalina, Fenotiazinas, Trypanosoma cruzi

ESR spin trapping studies of free radicals generated from nitrofuran derivative analogues of nifurtimox by electrochemical and Trypanosoma cruzi reduction

Tags: Estres Oxidativo, Nitrofuranos derivados, Radicales libres, Trypanosoma cruzi

Sialyl-Tn antigen expression and O-linked GalNac-Thr synthesis by Trypanosoma cruzi

Tags: Antígenos, Trypanosoma cruzi

Specific cleavage sites on human IgG subclasses by cruzipain the major cysteine proteinase from Trypanosoma cruzi

Tags: Inmunoglobulina-IgG, Trypanosoma cruzi

New potent 5 substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth : quantitative structure activity relationship studies.

Tags: Trypanosoma cruzi

Benzo [1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosmal drugs. Part 3 : Substituents clustering methodology in the search for new active compounds.

Tags: Agentes tripanocidas, Benceno, Estructura Molecular, Nifurtimox, Oxadiazoles, Oxidación, Productos farmacéuticos, Trypanosoma cruzi

Anti-T. cruzi activities and QSAR studies of 3-arylquinoxaline-2-carbonitrile di-N-oxides.

Tags: Antiparasitarios, Antitripanosomas, Enfermedad de chagas, Productos farmacéuticos, Trypanosoma cruzi

Theoretical EPR study of Nitroindazoles: 3-Alkoxy, 3-Hydroxy and 3-Oxo Derivatives.

Tags: Antitripanosomas, Espectroscopía, Trypanosoma cruzi

Development of second generation amidinohydrazones, thio- and semicarbazones as Trypanosoma cruzi-inhibitors bearing benzofuroxan and benzimidazole 1,3-dioxide core scaffolds.

Tags: Antiparasitarios, Enfermedad de chagas, Productos farmacéuticos, Trypanosoma cruzi

Homology modeling of T. cruzi and L. major NADH-dependent fumarate reductases: ligand docking, molecular dynamics validation, and insights on their binding modes

Tags: Antitripanosomas, Leishmaniasis, Tripanosomiasis, Trypanosoma cruzi

Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth : synthesis, biological evaluation, and structure–activity relationships

Tags: Citotoxicidad, Compuestod Heterociclicos, Trypanosoma cruzi

Synthesis and in vitro activity of limonene derivatives against Leishmania and Trypanosoma.

Tags: Leishmaniasis, Síntesis Química, Trypanosoma cruzi

Imidazolium compounds are active against all stages of Trypanosoma cruzi

Tags: Enfermedad de chagas, Trypanosoma cruzi

Trypanosoma cruzi chemical proteomics using immobilized benznidazole

Tags: Trypanosoma cruzi

Risedronate metal complexes potentially active against Chagas disease.

Tags: Complejos, Enfermedad de chagas, Metales, Parasitología, Productos farmacéuticos, Trypanosoma cruzi

Synthetic medicinal chemistry in chagas´disease : Compounds at the final stage of "hit-to-lead" phase

Tags: Enfermedad de chagas, Trypanosoma cruzi

Mode of action of Nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi : is oxidative stress involved?

Tags: Enfermedad de chagas, Estres Oxidativo, Nifurtimox, Tripanosomiasis, Trypanosoma cruzi

New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors : a deeper insight into the mechanism of inhibition.

Tags: Enfermedad de chagas, Trypanosoma cruzi

Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite specific fumarate reductase

Tags: Antitripanosomas, Complejos, Enfermedad de chagas, Paladio, Parasitología, Platino, Trypanosoma cruzi

Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity

Tags: Antiparasitarios, Productos farmacéuticos, Trypanosoma cruzi

Browse Items (77 total)

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Separación de fracciones de "butter oil" y su aplicación en formulaciones cosméticas

Syntesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives.

Synthesis and Antichagasic Properties of New 1,2,6-Thiadiazin-3,5-dione 1,1-Dioxides and Related compounds.

New thiadizine derivatives with activity against Trypanosoma cruzi amastigotes.

Synthesis and anti-trypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivates. Structure-activity relationships.

Novel antiprotozoal products : imidazole and benzimidazole N-oxide derivatives and related compounds.

Quinoxaline NNï-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi. Structure activity relationships.

ESR spin trapping studies of free radicals generated from nitrofuran derivative analogues of nifurtimox by electrochemical and Trypanosoma cruzi reduction

Sialyl-Tn antigen expression and O-linked GalNac-Thr synthesis by Trypanosoma cruzi

Specific cleavage sites on human IgG subclasses by cruzipain the major cysteine proteinase from Trypanosoma cruzi

New potent 5 substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth : quantitative structure activity relationship studies.

Benzo [1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosmal drugs. Part 3 : Substituents clustering methodology in the search for new active compounds.

Anti-T. cruzi activities and QSAR studies of 3-arylquinoxaline-2-carbonitrile di-N-oxides.

Theoretical EPR study of Nitroindazoles: 3-Alkoxy, 3-Hydroxy and 3-Oxo Derivatives.

Development of second generation amidinohydrazones, thio- and semicarbazones as Trypanosoma cruzi-inhibitors bearing benzofuroxan and benzimidazole 1,3-dioxide core scaffolds.

Homology modeling of T. cruzi and L. major NADH-dependent fumarate reductases: ligand docking, molecular dynamics validation, and insights on their binding modes

Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth : synthesis, biological evaluation, and structure–activity relationships

Synthesis and in vitro activity of limonene derivatives against Leishmania and Trypanosoma.

Imidazolium compounds are active against all stages of Trypanosoma cruzi

Trypanosoma cruzi chemical proteomics using immobilized benznidazole

Risedronate metal complexes potentially active against Chagas disease.

Synthetic medicinal chemistry in chagas´disease : Compounds at the final stage of "hit-to-lead" phase

Mode of action of Nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi : is oxidative stress involved?

New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors : a deeper insight into the mechanism of inhibition.

Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite specific fumarate reductase

Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity